Mitochondrial protein degradation

Summary
Species
Rattus norvegicus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TfamADPATPQ91ZW1LONP1 hexamerLONP1:substrate protein (mitochondrial matrix)Substrate of LONP1 (mitochondrial matrix)H2OPiLONP1:substrate protein (mitochondrial inner membrane)Substrate of LONP1 (mitochondrial inner membrane)CLPXPCLPXP:substrate protein (mitochondrial matrix)Substrate of CLPXP (mitrochondrial matrix)Substrate of AFG3L2 (mitochondrial matrix)AFG3L2:substrate protein (mitochondrial matrix)AFG3L2:Zn2+ hexamerAFG3L2:substrate protein (mitochondrial inner membrane)Substrate of AFG3L2 (mitochondrial inner membrane)AFG3L2:Zn2+:SPG7:Zn2+ heterohexamerAFG3L2:SPG7:SMDT1Smdt1Homologues of NDUFA13HTRA2:NDUFA13HTRA2 trimerHomologues of NDUFA13(20-40)Homologues of NDUFA13(109-144)H2OHomologues of NDUFA13(41-49)Homologues of NDUFA13(50-68)Homologues of NDUFA13(2-19)Homologues of NDUFA13(69-99)Homologues of NDUFA13(100-108)P08592APP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025