GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **276 - 300** of **557** in total

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Pathway Name ▲	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Keratan sulfate degradation	Aggrecan core protein Beta-galactosidase Beta-galactosidase Beta-hexosaminidase subunit alpha Beta-hexosaminidase Fibromodulin Galactosidase beta 1 like Keratocan Lumican N-acetylglucosamine-6-sulfatase Osteomodulin Proline and arginine rich end leucine rich repeat protein	A0A140T890 A0A3Q1NDQ7 A6QQQ3 E1BCP9 F1MXZ0 F1MY73 F1N368 G3X6Y4 H7BWW2 P13605 Q05443 Q0V8R6	ACAN FMOD GLB1 GLB1L GLB1L2 GNS HEXA HEXB KERA LDC LUM OMD PRELP	Bos taurus (cattle)	G09546QO G20239CJ G27025MB G50451AA G80016QC G82768YB G85384LV
Keratinization	DSC1 protein Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoplakin IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein Junction plakoglobin KRT15 protein KRT32 protein KRT4 protein KRT82 protein KRTAP1-1 protein KRTAP4-7 protein Keratin 14 Keratin 16 Keratin 17 Keratin 18 Keratin 23 Keratin 24 Keratin 2 Keratin 31 Keratin 31 Keratin 33A Keratin 36 Keratin 36 Keratin 36 Keratin 37 Keratin 39 Keratin 3 Keratin 6A Keratin 6A Keratin 6A Keratin 77 Keratin 79 Keratin 83 Keratin 84 Keratin 85 Keratin 86 Keratin 9 Keratin associated protein 19-5 Keratin associated protein 3-1 Keratin associated protein 8-1 Keratin associated protein 9-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 17 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 26 Keratin, type I cytoskeletal 27 Keratin, type I cytoskeletal 28 Keratin, type I cytoskeletal 40 Keratin, type II cuticular Hb1 Keratin, type II cytoskeletal 1 Keratin, type II cytoskeletal 5 Keratin, type II cytoskeletal 72 Keratin, type II cytoskeletal 73 Keratin, type II cytoskeletal 74 Keratin, type II cytoskeletal 75 Keratin, type II cytoskeletal 78 Keratin, type II cytoskeletal 7 Keratin, type II cytoskeletal 80 Keratin, type II cytoskeletal 8 Keratin-associated protein 10-8 Keratin-associated protein 12-1-like Keratin-associated protein 12-1-like Keratin-associated protein 12-2 Keratin-associated protein 3-3 Keratin-associated protein 3-3 Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein LOC618938 protein LOC787225 protein Plakophilin 1 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A140T867 A0A140T8B6 A0A3Q1LFA4 A0A3Q1LJB2 A0A3Q1LP03 A0A3Q1LQD4 A0A3Q1LSL9 A0A3Q1LUM3 A0A3Q1LYD7 A0A3Q1LZF2 A0A3Q1M0F6 A0A3Q1M0W3 A0A3Q1M139 A0A3Q1M4F4 A0A3Q1M8D5 A0A3Q1MB50 A0A3Q1MDN1 A0A3Q1MEE6 A0A3Q1MFR3 A0A3Q1MLT3 A0A3Q1MN32 A0A3Q1MPF8 A0A3Q1MQC4 A0A3Q1MYR8 A0A3Q1N0A2 A0A3Q1N1L4 A0A3Q1N3D2 A0A3Q1NF50 A0A3Q1NHC3 A0A452DI61 A0A452DIJ6 A0JND2 A3KMY1 A3KN27 A4IFP2 A5D7M6 A5PJJ0 A5PJJ4 A6H712 A6QNX5 A6QNZ7 A6QP35 A6QP90 A6QR67 A7E345 A7YWJ9 A7YWK3 A7YWM2 E1B898 E1B9D7 E1BAH7 E1BFG1 E1BIW5 E1BKT9 E1BM91 F1MC11 F1MFC2 F1MFW9 F1MI65 F1MI98 F1MIW8 F1MJ11 F1MKE7 F1MPK1 F1MTA9 F1MU12 F1MUY2 F1MXJ3 F1MZF2 F1N362 F1N3T1 F1N566 F6RZX2 F6S1Q0 G3MX57 G3MX98 G3MYE1 G3MZ71 G3N073 G3N0V2 G3N156 G3N2U6 G3X7W8 M0QVY0 P08728 Q05B44 Q05B46 Q08D91 Q0P5J4 Q0P5J6 Q0VD04 Q148H4 Q148H6 Q148H8 Q148I8 Q17QL7 Q24JX9 Q29S21 Q8SPJ1	DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP KRT1 KRT10 KRT13 KRT14 KRT15 KRT16 KRT17 KRT18 KRT19 KRT2 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33A KRT33B KRT35 KRT36 KRT37 KRT39 KRT4 KRT40 KRT5 KRT6B KRT7 KRT72 KRT73 KRT74 KRT75 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT84 KRT85 KRT86 KRT9 KRTAP1-1 KRTAP10-8 KRTAP11-1 KRTAP12-2 KRTAP19-5 KRTAP24-1 KRTAP27-1 KRTAP3-1 KRTAP3-3 KRTAP4-7 KRTAP8-1 LOC100294937 LOC100300014 LOC101902114 LOC112442669 LOC112446672 LOC112446673 LOC112446984 LOC112448008 LOC507184 LOC616413 LOC618359 LOC618938 LOC787051 LOC787225 LOC787600 PKP1 PKP4	Bos taurus (cattle)
Ketone body catabolism	Acetyl-CoA acetyltransferase, mitochondrial D-beta-hydroxybutyrate dehydrogenase, mitochondrial Succinyl-CoA	A0A3Q1LIX4 Q02337 Q29RZ0	ACAT1 BDH BDH1 OXCT1	Bos taurus (cattle)
LDL clearance	AP-1 complex subunit beta-1 AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma Apolipoprotein B Carboxylic ester hydrolase Clathrin heavy chain 1 Clathrin light chain A LDLRAP1 protein Low-density lipoprotein receptor NPC intracellular cholesterol transporter 2 Neutral cholesterol ester hydrolase 1 O-acyltransferase O-acyltransferase	A0A3Q1LVF9 A4IFV0 E1BNR0 F1MI11 F1N277 P01131 P04973 P49951 P79345 Q08DS7 Q0VCK5 Q17QC5 Q1JQE6 Q3T0N9 Q3ZC13	AADACL1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 APOB CES3 CLTA CLTC LDLR LDLRAP1 NCEH1 NPC2 SOAT1 SOAT2	Bos taurus (cattle)
LGI-ADAM interactions	ADAM metallopeptidase domain 22 ADAM metallopeptidase domain 23 Discs large MAGUK scaffold protein 4 LGI4 protein Leucine rich repeat LGI family member 2 Leucine rich repeat LGI family member 3 Leucine-rich glioma-inactivated protein 1 Syntaxin-1A Syntaxin-1B Voltage-dependent calcium channel gamma-2 subunit Voltage-dependent calcium channel gamma-3 subunit Voltage-dependent calcium channel gamma-4 subunit Voltage-dependent calcium channel gamma-8 subunit	A0A3Q1LKG2 A0A3Q1MVZ5 A0A3Q1NF99 A0JNG9 A6QLD0 E1BFY8 F1MM66 F1MV40 F1MZT1 P32850 P61267 Q0VD05 Q5E9T6	ADAM22 ADAM23 CACNG2 CACNG3 CACNG4 CACNG8 DLG4 LGI1 LGI2 LGI3 LGI4 STX1A STX1B STX1B2	Bos taurus (cattle)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	Catenin beta-1 Interferon regulatory factor 3 histone acetyltransferase histone acetyltransferase	E1B8D6 F1MD32 Q0VCX4 Q4JF28	CREBBP CTNNB1 EP300 IRF3	Bos taurus (cattle)
Lactose synthesis	Beta-1,4-galactosyltransferase 1 Solute carrier family 2, facilitated glucose transporter member 1	P08037 P27674	B4GALT1 GALT GGTB2 GLUT1 SLC2A1	Bos taurus (cattle)	G58161NS G74621DY
Laminin interactions	Integrin alpha-3 Integrin beta Integrin beta Integrin subunit alpha 6 Integrin subunit alpha 7 Laminin subunit alpha 4 Multiple EGF like domains 6 NID1 protein	A0A140T8D2 A0A3Q1M8K4 A0A3Q1MJT5 A0A3Q1MRM3 A0A3Q1N9E9 A6QNS6 E1BGA0 F1MMS9	ITGA3 ITGA6 ITGA7 ITGB1 ITGB4 LAMA4 MEGF6 NID1	Bos taurus (cattle)
Lectin pathway of complement activation	Collectin subfamily member 10 Collectin-11 Ficolin-2 MBL associated serine protease 1 MBL associated serine protease 2 Mannose-binding protein C	A0A3Q1MLF4 E1BJ49 F1MVS9 O02659 Q17QH6 Q5I2E5	COLEC10 COLEC11 FCN2 MASP1 MASP2 MBL	Bos taurus (cattle)	G49108TO G57321FI
Leukotriene receptors	CYSLTR2 protein Cysteinyl leukotriene receptor 1 G protein-coupled receptor 17 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2	A2VEA2 A5PKG3 A7MBH4 F1MRY8 Q3T181	CYSLTR1 CYSLTR2 GPR17 LTB4R LTB4R2	Bos taurus (cattle)
Lewis blood group biosynthesis	Alpha-(1,3)-fucosyltransferase 7 Alpha-(1,3)-fucosyltransferase Alpha-(1,3)-fucosyltransferase Beta-1,4-N-acetyl-galactosaminyltransferase 2 Fucosyltransferase Fucosyltransferase Fucosyltransferase Hexosyltransferase Hexosyltransferase L-Fucosyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 Type 2 lactosamine alpha-2,3-sialyltransferase	A0A3Q1LUC6 A0A3Q1MGH3 A0A452DJH9 E1BIT9 F1MBS8 F1MDG4 F1MUS1 F1MWE7 F1N557 F1N751 G3MZR2 Q2HJA3 Q3T0R9 Q6H8M7	B3GALT2 B3GALT4 B4GALNT2 FUT10 FUT11 FUT2 FUT4 FUT6 FUT7 FUT9 SIAT10 ST3GAL3 ST3GAL4 ST3GAL6 ST6GALNAC6	Bos taurus (cattle)	G39211DH G81971FM G83633HB G90387AM G98173LG
Lysosomal oligosaccharide catabolism	Alpha-mannosidase Beta-mannosidase Lysosomal alpha-mannosidase alpha-mannosidase	A0A3Q1MEZ5 A0A3S5ZPJ9 F1MWT0 Q29451	LOC528518 MAN2B1 MAN2C1 MANB MANBA	Bos taurus (cattle)	G00027MO G25577BM G28233ME G70323CJ G90333CG
Lysosome Vesicle Biogenesis	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit beta AP complex subunit sigma AP-1 complex subunit gamma AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-4 complex subunit mu-1 AP-4 complex subunit sigma-1 Adaptor related protein complex 4 subunit epsilon 1 Amyloid-beta A4 protein Beta-arrestin-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 Cathepsin Z Cation-dependent mannose-6-phosphate receptor Charged multivesicular body protein 2a Clathrin heavy chain 1 Clathrin light chain A Clathrin light chain B Clavesin-1 Clavesin-2 Deoxyribonuclease-2-alpha Hepatocyte growth factor-regulated tyrosine kinase substrate N-acetylglucosamine-6-sulfatase SH3 domain containing GRB2 like 2, endophilin A1 Thioredoxin domain containing 5 Vesicle-associated membrane protein 2 Vesicle-associated membrane protein 8	A0A3Q1LMK0 A0A3Q1LUG2 A0A3Q1LUG9 A0A3Q1LWC6 A0A3Q1M481 A0A3Q1M952 E1BE20 E1BHP4 E1BNA3 F1MXZ0 F1MZ33 F6QYT8 P04973 P04975 P05689 P11456 P17870 P49951 P63026 P84080 Q08DX1 Q0V8S0 Q1JQ98 Q29RY8 Q2KJ81 Q2NKW0 Q3SYW1 Q3T0U5 Q3T0Y8 Q3ZBB6 Q3ZBS3	AP1B1 AP1G1 AP1G2 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP4B1 AP4E1 AP4M1 AP4S1 APP ARF1 ARRB1 BLOC1S1 CHMP2A CLTA CLTB CLTC CLTLB CLVS1 CLVS2 CTSZ DNASE2 GNS HGS M6PR SH3GL2 SYB2 TXNDC5 VAMP2 VAMP8	Bos taurus (cattle)
Lysosphingolipid and LPA receptors	Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Phospholipid phosphatase related 2 Phospholipid phosphatase related 3 Phospholipid phosphatase related 4 Phospholipid phosphatase related 5 Phospholipid phosphatase-related protein type 1 S1PR3 protein Sphingosine 1-phosphate receptor 1 Sphingosine-1-phosphate receptor 2 Sphingosine-1-phosphate receptor 5	A0A3Q1LQD3 A0A3Q1M4L7 A0A3Q1M9C6 A2VDV6 A6QR17 E1BJF3 E1BLD8 F1MJ26 F1MU59 F1MV28 F1MX11 Q3ZC80 Q5E9P3	EDG1 GPR92 LPAR1 LPAR2 LPAR3 LPAR5 PLPPR1 PLPPR2 PLPPR3 PLPPR4 PLPPR5 S1PR1 S1PR2 S1PR3 S1PR5	Bos taurus (cattle)
MAPK1 (ERK2) activation	Dual specificity mitogen-activated protein kinase kinase 2 Interleukin 6 cytokine family signal transducer Interleukin 6 receptor Interleukin-6 Mitogen-activated protein kinase 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A3S5ZPX3 E1BCP6 E1BD36 E1BJQ3 F1MCX4 F1N0D6 F1N339 P26892 P46196	ERK2 IL6 IL6R IL6ST JAK1 JAK2 MAP2K2 MAPK1 PRKM1 PTPN11 TYK2	Bos taurus (cattle)
MAPK3 (ERK1) activation	Cyclin-dependent kinase 1 Dual specificity mitogen-activated protein kinase kinase 1 Interleukin 6 cytokine family signal transducer Interleukin 6 receptor Interleukin-6 Mitogen-activated protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	E1B8P9 E1BCP6 E1BD36 E1BJQ3 F1MCX4 F1N0D6 F1N339 P26892 P48734 Q0VD16	CDC2 CDK1 CDKN1 IL6 IL6R IL6ST JAK1 JAK2 MAP2K1 MAPK3 PTPN11 TYK2	Bos taurus (cattle)
MAPK6/MAPK4 signaling	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDC42 effector protein (Rho GTPase binding) 3 CDC42 effector protein 5 Cdc42 effector protein 2 Cell division control protein 42 homolog Cyclin D3 Cyclin-dependent kinase 1 DnaJ homolog subfamily B member 1 ETS variant transcription factor 4 Exportin 1 Forkhead box O3 Forkhead box protein O1 Heat shock protein beta-1 MAPK activated protein kinase 5 Mitogen-activated protein kinase 6 Nuclear receptor coactivator Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Septin-7 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase mitogen-activated protein kinase non-specific serine/threonine protein kinase protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A3Q1LSY0 A0A3Q1M0G8 A0A3Q1M3S4 A0A3Q1MTC5 A0A452DI44 A0A452DIY4 A0A452DJE2 A0A452DJI7 A7MBA2 E1BD83 E1BE98 E1BFS7 E1BLR2 F1MBI1 F1MH23 F1MLV1 F1MV86 F1MVD0 F1MVV5 F1MWE0 F1MXE4 F1MYH8 F1N4K5 F1N6Z0 G3N010 G5E577 G5E589 P00517 P0CG53 P0CH28 P33672 P48734 P56701 P62194 P62992 P63048 Q08DN6 Q08E52 Q17QP9 Q2KI42 Q2KI46 Q2KJ25 Q2KJ46 Q2KJ93 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3MI00 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3T149 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	BORG1 CCND3 CDC14A CDC14B CDC2 CDC42 CDC42EP2 CDC42EP3 CDC42EP5 CDK1 CDKN1 CEP2 DNAJB1 ETV4 FOXO1 FOXO3 HSP27 HSPB1 MAPK4 MAPK6 MAPKAPK5 NCOA3 PAK1 PAK2 PAK3 PRKACA PRKACB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SEPTIN7 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 XPO1	Bos taurus (cattle)
MET activates PTK2 signaling	Focal adhesion kinase 1 Hepatocyte growth factor receptor Hepatocyte growth factor Integrin alpha-3 Integrin beta Integrin subunit alpha 2 Laminin subunit alpha 4 Multiple EGF like domains 6 Tyrosine-protein kinase	A0A140T8D2 A0A3Q1MJT5 A0A3Q1N508 A0A3Q1N9E9 E1BIM8 F1MBA3 F1MMS9 F1MZD6 Z4YHD9	HGF ITGA2 ITGA3 ITGB1 LAMA4 MEGF6 MET PTK2 SRC	Bos taurus (cattle)
MHC class II antigen presentation	ADP-ribosylation factor 1 AP complex subunit beta AP complex subunit sigma AP-1 complex subunit beta-1 AP-1 complex subunit gamma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-1 complex subunit sigma-1A AP-1 complex subunit sigma-2 AP-2 complex subunit alpha-2 AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma Actin-related protein 10 Alpha-centractin BOLA-DQA1 protein Beta-centractin BoLA-DR-alpha CD74 molecule Calnexin Carboxypeptidase Cathepsin B Cathepsin D Cathepsin F Cathepsin K Cathepsin O Cathepsin S Centromere protein E Clathrin heavy chain 1 Clathrin light chain A Cytoplasmic dynein 1 intermediate chain 1 Dipeptidyl peptidase 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynamin-1 Dynein cytoplasmic 1 heavy chain 1 Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-1 F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha Gamma-interferon-inducible lysosomal thiol reductase Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Kinesin family member 11 Kinesin family member 15 Kinesin family member 23 Kinesin family member 5A Kinesin light chain Kinesin light chain Kinesin light chain Kinesin light chain Kinesin-like protein KIF20A Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Legumain Lymphocyte activating 3 MHC class II DO-beta chain MHC class II antigen MHC class II antigen MHC class II antigen Major histocompatibility complex, class II, DM alpha Major histocompatibility complex, class II, DO alpha Major histocompatibility complex, class II, DQ alpha 5 Major histocompatibility complex, class II, DY alpha Oxysterol-binding protein Pro-cathepsin H Procathepsin L Protein SEC13 homolog Protein transport protein SEC23 Protein transport protein Sec24A Protein transport protein Sec31A Rab interacting lysosomal protein Rac GTPase activating protein 1 SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SH3 domain containing GRB2 like 2, endophilin A1 Small COPII coat GTPase SAR1B Spectrin beta chain dynamin GTPase	A0A140T8D4 A0A3Q1LMK0 A0A3Q1LVF9 A0A3Q1LYZ8 A0A3Q1M088 A0A3Q1M3Y3 A0A3Q1M481 A0A3Q1M952 A0A3Q1MEG8 A0A3Q1MG61 A0A3Q1MIC9 A0A3Q1MR65 A0A3Q1MUW5 A0A3Q1MWH8 A0A3Q1MXL6 A0A3Q1NEU9 A0A452DJ87 A4FUA8 A4IFE3 A6H6Y1 A6H7H2 A6QNT8 A6QPN6 A6QQE7 A7Z066 E1B8X6 E1BBI8 E1BC41 E1BF29 E1BG49 E1BIU0 E1BJP2 E1BKE3 E1BLV1 E1BLZ1 E1BMN5 E1BMP2 E1BPI9 E1BPR4 F1MBQ0 F1MHT7 F1MJU5 F1ML60 F1MLV2 F1MMR6 F1MV07 F1MVW5 F1MWR7 F1N0X9 F1N0Y3 F1N455 F2Z4F0 F6RPS1 G3MWT2 P04973 P07688 P25326 P25975 P49951 P61285 P84080 Q08DF4 Q08DH4 Q08DS7 Q08DX1 Q0P5A1 Q0VCK5 Q0VCU3 Q148G7 Q17QC5 Q1JQ98 Q29RQ3 Q29RT6 Q2KII9 Q2KJ81 Q30309 Q32KS3 Q3MHR3 Q3SYW1 Q3T0I2 Q3T0T7 Q3ZBD2 Q3ZBS3 Q3ZC13 Q3ZCC9 Q3ZCF0 Q58DW7 Q5E968 Q5E997 Q5KTP6 Q70IB5	ACTR10 ACTR1A ACTR1B AP1B1 AP1G1 AP1M1 AP1M2 AP1S1 AP1S2 AP1S3 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 ARP10 BLA-DQB BOLA-DMA BOLA-DMB BOLA-DOA BOLA-DQA1 BOLA-DQA2 BOLA-DQA5 BOLA-DRA BOLA-DRB2 BOLA-DRB3 BOLA-DYA BOLA-DYB BoLA-DIB BoLA-DOB BoLA-DRA BoLA-DYB CANX CAPZA1 CAPZA2 CAPZA3 CD74 CENPE CLTA CLTC CTSA CTSB CTSC CTSD CTSF CTSH CTSK CTSL CTSL1 CTSO CTSS DCTN1 DCTN2 DCTN3 DCTN4 DCTN5 DCTN6 DMB DNCL1 DNM1 DNM3 DYB DYNC1H1 DYNC1I1 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HLA-DMB HLA-DRA IFI30 KIF11 KIF15 KIF20A KIF22 KIF23 KIF2B KIF3A KIF5A KIF5B KLC1 KLC2 KLC3 KLC4 LAG3 LGMN LOC100848815 OSBPL1A RACGAP1 RILP SAR1B SEC13 SEC13L1 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SH3GL2 SPTBN2 canx	Bos taurus (cattle)
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 5'-AMP-activated protein kinase subunit gamma-3 Acetyl-CoA carboxylase kinase Autophagy and beclin 1 regulator 1 Autophagy protein 5 Autophagy related 14 Autophagy related 16 like 1 Autophagy-related protein 101 Autophagy-related protein 13 Autophagy-related protein 9 Autophagy-related protein 9A Beclin-1 CHMP4B protein Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 7 Chromatin modifying protein 4C Chromatin modifying protein 6 Cysteine protease ATG4B Cysteine protease Cysteine protease Cysteine protease Dynein light chain 1, cytoplasmic Dynein light chain 2, cytoplasmic Gamma-aminobutyric acid receptor-associated protein-like 1 Gamma-aminobutyric acid receptor-associated protein-like 2 Gamma-aminobutyric acid receptor-associated protein MAP1LC3C protein Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Myotubularin related protein 14 Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein kinase AMP-activated non-catalytic subunit beta 2 Protein kinase AMP-activated non-catalytic subunit gamma 2 RB1 inducible coiled-coil 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein A Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 Serine/threonine-protein kinase mTOR TSC complex subunit 1 Target of rapamycin complex subunit LST8 UV radiation resistance associated Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 Unc-51 like autophagy activating kinase 1 WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4 WD repeat domain, phosphoinositide interacting 1 non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1LXA9 A0A3Q1LYC8 A0A3Q1LZ59 A0A3Q1MME8 A0A3Q1MSS5 A0A3Q1MUP4 A0A3Q1MVT8 A2VDY3 A4FUE9 A6H704 A6QLW1 A7MB94 E1B986 E1BAQ5 E1BFB4 E1BGS8 E1BH45 F1MBG5 F1MFB2 F1MG06 F1MJ23 F1MM99 F1MPW0 F1MQ92 F1MQV7 F1MW27 F1MZE2 F1N3U6 F1N5L1 F2Z4I1 G5E5G3 O41515 P58108 P60519 P61285 Q08DY8 Q08E32 Q0IIH0 Q0VCL3 Q0VD29 Q148L0 Q17QQ1 Q17QU5 Q2HJ23 Q2HJ35 Q2HJE0 Q2KJ60 Q2LL38 Q2M2U3 Q3MHR3 Q3MQ24 Q3SX42 Q3SX43 Q3SZ68 Q3T0D8 Q3T0U5 Q3T132 Q3T904 Q4A1L4 Q58CS7 Q5BIS9 Q6PZ03 Q8HYB6 Q9GJW7	AMBRA1 APG4B ATG10 ATG101 ATG12 ATG13 ATG14 ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9 ATG9A ATG9B AUT2B BECN1 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 DNCL1 DYNLL1 DYNLL2 GABARAP GABARAPL1 GABARAPL2 GBL GEF2 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 LST8 MAP1ALC3 MAP1LC3 MAP1LC3A MAP1LC3B MAP1LC3C MGC138057 MLST8 MTMR14 MTOR PIK3C3 PIK3R4 PRKAA1 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RB1CC1 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 TSC1 ULK1 UVRAG VPS24 WDR45 WDR45B WIPI1 WIPI2	Bos taurus (cattle)
Malate-aspartate shuttle	Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Malate dehydrogenase, cytoplasmic Malate dehydrogenase, mitochondrial Mitochondrial 2-oxoglutarate/malate carrier protein Mitochondrial glutamate carrier 1 Solute carrier family 25 member 12	A0A3Q1M9V5 P12344 P22292 P33097 Q08DK4 Q32LG3 Q3T145	GC1 GOT1 GOT2 MDH1 MDH2 SLC20A4 SLC25A11 SLC25A12 SLC25A22	Bos taurus (cattle)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Citrate synthase lysine methyltransferase Citrate synthase, mitochondrial Frataxin, mitochondrial Iron-sulfur cluster assembly 1 homolog, mitochondrial Iron-sulfur cluster assembly 2 homolog, mitochondrial Iron-sulfur cluster assembly enzyme Isocitrate dehydrogenase [NADP], mitochondrial LYR motif-containing protein 4 NAD-dependent protein deacetylase Succinate dehydrogenase [ubiquinone] cytochrome b small subunit Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase assembly factor 1, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial Succinate dehydrogenase assembly factor 3, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial cysteine desulfurase	A0A3Q1LZ07 A0A3Q1M728 A5PKG4 A8PU71 E1BE08 G5E521 G5E6M7 P20004 P35720 Q04467 Q05B87 Q0P574 Q0VCG0 Q17QE6 Q29RK1 Q29RZ0 Q2TBG7 Q3SZG8 Q3ZBC2 V6F7N8	ACAT1 ACN9 ACO2 CS CSKMT CYB560 FRDA FXN HBLD1 HBLD2 IDH2 ISCA1 ISCA2 ISCU ISD11 LYRM4 LYRM8 NFS1 PGL2 SDH5 SDHA SDHAF1 SDHAF2 SDHAF3 SDHB SDHC SDHD SIRT3	Bos taurus (cattle)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensinogen Carboxylic ester hydrolase Carboxypeptidase A3 Carboxypeptidase B2 Carboxypeptidase B Cathepsin D Cathepsin Z Neprilysin Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Renin receptor renin	A0A3Q1LTF9 A0A3Q1MQJ1 A0A452DJE0 E1B8U1 E1BAD2 E1BIP7 E1BK06 E1BPL8 F1MEM5 F1MMR6 F1MZL4 P00732 P01017 P05689 P81134 Q2KIG3	ACE2 AGT ATP6AP2 ATP6IP2 CES1 CPA3 CPB CPB1 CPB2 CTSD CTSZ ENPEP LOC100139881 LOC509956 LOC540321 LOC617313 MME REN SERPINA8	Bos taurus (cattle)
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase 10-formyltetrahydrofolate dehydrogenase 5-formyltetrahydrofolate cyclo-ligase C-1-tetrahydrofolate synthase, cytoplasmic Dihydrofolate reductase Folate receptor 2 (Fetal) Folylpolyglutamate synthase Methylenetetrahydrofolate reductase Monofunctional C1-tetrahydrofolate synthase, mitochondrial Proton-coupled folate transporter Reduced folate transporter Serine hydroxymethyltransferase, mitochondrial Serine hydroxymethyltransferase Solute carrier family 25 member 32 methenyltetrahydrofolate cyclohydrolase methenyltetrahydrofolate cyclohydrolase	A0A140T872 A0A140T896 A0A3Q1MU29 A0A3Q1NGK6 A0A452DI11 A4FUD0 E1BDG9 E1BMG9 E1BNJ2 F1MWN5 G3X7X2 Q05B81 Q0VCN9 Q0VCR7 Q1RMT3 Q3SZ20	ALDH1L1 ALDH1L2 DHFR FOLR2 FPGS HCP1 MTHFD1 MTHFD1L MTHFD2 MTHFD2L MTHFR MTHFS PCFT SHMT1 SHMT2 SLC19A1 SLC25A32 SLC46A1	Bos taurus (cattle)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase	E1BM12 P27117 P50243 Q3SZA5	AMD1 ODC ODC1 SMS SRM	Bos taurus (cattle)

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