GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **501 - 525** of **557** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase Tyrosine-protein kinase	E1BCP6 F1MEQ7 F1MJE0 F1N261	EPOR IRS2 JAK2 LYN	Bos taurus (cattle)
Costimulation by the CD28 family	Inducible T cell costimulator ligand Inducible T-cell costimulator Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3	E1BCU8 F1MDQ5 P23726 P23727 P32871 Q58DF9	ICOS ICOSLG PIK3CA PIK3R1 PIK3R2 PIK3R3	Bos taurus (cattle)
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium channel subfamily K member Potassium two pore domain channel subfamily K member 16	E1BEH1 Q8HZT2	KCNK16 KCNK17	Bos taurus (cattle)
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53	Bos taurus (cattle)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 5 RPE-retinal G protein-coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1	E1BEK2 E1BNN4 F1MR98 P02699 P47803 P51490 Q9BGI7	BCP OPN1LW OPN1SW OPN4 OPN5 RCP RGR RHO RRH	Bos taurus (cattle)
Glucocorticoid biosynthesis	11-beta-hydroxysteroid dehydrogenase type 2 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase Corticosteroid-binding globulin Pro-opiomelanocortin Steroid 17-alpha-hydroxylase/17,20 lyase Steroid 21-hydroxylase steroid 11beta-monooxygenase steroid 11beta-monooxygenase steroid 11beta-monooxygenase	E1BF81 F1MG97 F1MU47 F1MWH3 F1N3U0 P00191 P01190 P05185 P14893	CBG CYP11B1 CYP17 CYP17A1 CYP21 CYP21A1 CYP21A2 HSD11B2 HSD3B LOC112449566 POMC SERPINA6	Bos taurus (cattle)
Digestion of dietary carbohydrate	Alpha-amylase Lactase Maltase-glucoamylase 2 (putative) Sucrase-isomaltase chitinase	E1BGH5 E1BK89 F1MH27 F1MP21 G3N3S2	CHIA LCT LOC539383 MGAM2 SI	Bos taurus (cattle)	G58161NS G74621DY G93924TT G96370VA
Activation of C3 and C5	Complement C2 Complement C3 Complement C5 Complement component 4A Complement factor B Uncharacterized protein	E1BH06 F1MVK1 F1MY85 P81187 Q2UVX4 Q3SYW2	BF C2 C3 C4A C5 CFB LOC107131209	Bos taurus (cattle)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pro-FMRFamide-related neuropeptide FF Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide	E1BHL6 F1MG23 F1MXG2 F1MXG7 F1N1Y7 Q0GBZ5 Q9TUX7	HCRTR1 HCRTR2 NPFF NPFFR1 NPFFR2 QRFP QRFPR	Bos taurus (cattle)
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Serine/threonine-protein phosphatase PGAM5, mitochondrial Tyrosine-protein kinase Ubiquitin-like protein ATG12 Unc-51 like autophagy activating kinase 1	E1BIE7 E1BIM8 F1MFB2 F1MJ55 F1MZE2 F1N5S9 O41515 P67868 P68399 Q2HJ23 Q3MQ24	ATG12 ATG5 CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B FUNDC1 MAP1ALC3 MAP1LC3 MAP1LC3A MAP1LC3B PGAM5 SRC ULK1	Bos taurus (cattle)
Activated NTRK3 signals through PI3K	Neurotrophin-3 Tyrosine-protein kinase receptor Tyrosine-protein kinase	E1BIM8 G3N3T6 Q08DT3	NTF3 NTRK3 SRC	Bos taurus (cattle)
Cytosolic sensors of pathogen-associated DNA	Double-strand break repair protein	E1BIN9	MRE11	Bos taurus (cattle)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Procathepsin L Serpin family B member 13	E1BIP8 P25975 Q5E968	CTSK CTSL CTSL1 SERPINB13	Bos taurus (cattle)
Synthesis of 12-eicosatetraenoic acid derivatives	Arachidonate 12-lipoxygenase, 12R type Arachidonate 12-lipoxygenase, 12S type Arachidonate lipoxygenase 3 Glutathione peroxidase 1 Phospholipid hydroperoxide glutathione peroxidase Polyunsaturated fatty acid lipoxygenase ALOX15	E1BIT6 F1MFA8 F1MXD8 P00435 P27479 Q9N2J2	ALOX12 ALOX12B ALOX15 ALOXE3 GPX1 GPX4	Bos taurus (cattle)
Ficolins bind to repetitive carbohydrate structures on the target cell surface	Ficolin-2 MBL associated serine protease 1 MBL associated serine protease 2	E1BJ49 F1MVS9 Q5I2E5	FCN2 MASP1 MASP2	Bos taurus (cattle)	G49108TO G57321FI
Adenosine P1 receptors	Adenosine receptor A1 Adenosine receptor A2 Adenosine receptor A2b Adenosine receptor A3	E1BKU0 P28190 Q0VC81 Q1LZD0	ADORA1 ADORA2A ADORA2B ADORA3	Bos taurus (cattle)
Metabolism of polyamines	Ornithine decarboxylase S-adenosylmethionine decarboxylase proenzyme Spermidine synthase Spermine synthase	E1BM12 P27117 P50243 Q3SZA5	AMD1 ODC ODC1 SMS SRM	Bos taurus (cattle)
Glycerophospholipid catabolism	Glycerophosphocholine choline phosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	E1BMJ5 F1N5C8 Q3T0T0	ENPP6 GDE1 MIR16 PNPLA6	Bos taurus (cattle)
Condensation of Prometaphase Chromosomes	Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Condensin complex subunit 1 Condensin complex subunit 2 Non-SMC condensin I complex subunit G Structural maintenance of chromosomes protein Structural maintenance of chromosomes protein	E1BMZ9 F1MH70 F1MJ55 F1MUI7 F1MY41 F1N3G4 P67868 P68399	CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B NCAPD2 NCAPG NCAPH SMC2 SMC4	Bos taurus (cattle)
Scavenging by Class H Receptors	Apolipoprotein B SPARC Stabilin 1 Stabilin 2	E1BNJ1 E1BNR0 F1MYW1 P13213	APOB SPARC STAB1 STAB2	Bos taurus (cattle)
Attachment of GPI anchor to uPAR	GPAA1 protein GPI inositol-deacylase GPI-anchor transamidase Phosphatidylinositol glycan anchor biosynthesis class S Phosphatidylinositol glycan anchor biosynthesis class T Phosphatidylinositol glycan anchor biosynthesis class U Urokinase plasminogen activator surface receptor	E1BNQ0 F1MSF3 F1N4W0 F1N7F8 Q05588 Q3MHZ7 Q3T0N7	GPAA1 PGAP1 PIGK PIGS PIGT PIGU PLAUR	Bos taurus (cattle)
Scavenging by Class B Receptors	Apolipoprotein A-I Apolipoprotein B Platelet glycoprotein 4 Scavenger receptor class B member 1	E1BNR0 O18824 P15497 P26201	APOA1 APOB CD36 PAS4 SCARB1	Bos taurus (cattle)
Alternative complement activation	Complement C3 Complement factor B Complement factor D Granzyme M	E1BP32 P81187 Q2UVX4 Q3T0A3	BF C3 CFB CFD GZMM	Bos taurus (cattle)
CREB3 factors activate genes	CREB3 regulatory factor Cyclic AMP-responsive element-binding protein 3-like protein 3 Cyclic AMP-responsive element-binding protein 3 MBTPS1 protein Membrane-bound transcription factor site-2 protease	E1BPS0 Q08E55 Q0III2 Q3SYZ3 Q8SQ19	CREB3 CREB3L3 CREBRF MBTPS1 MBTPS2	Bos taurus (cattle)
Intracellular metabolism of fatty acids regulates insulin secretion	Platelet glycoprotein 4 long-chain-fatty-acid--CoA ligase long-chain-fatty-acid--CoA ligase	F1MBW3 F1MEX9 P26201	ACSL3 ACSL4 CD36 PAS4	Bos taurus (cattle)

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