GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Detoxification of Reactive Oxygen Species	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] Catalase Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytochrome c ERO1-like protein alpha Glutathione S-transferase Glutathione S-transferase Glutathione peroxidase 1 Glutathione peroxidase 3 Glutathione peroxidase 7 Glutathione peroxidase Glutathione peroxidase Glutathione reductase NADPH oxidase 4 NADPH oxidase 5 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peroxiredoxin-1 Peroxiredoxin-2 Peroxiredoxin-5, mitochondrial Peroxiredoxin-6 Probable glutathione peroxidase 8 Protein disulfide-isomerase Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Superoxide dismutase [Cu-Zn] Superoxide dismutase [Mn], mitochondrial Superoxide dismutase copper chaperone Thioredoxin reductase 1, cytoplasmic Thioredoxin reductase 2, mitochondrial Thioredoxin, mitochondrial Thioredoxin-dependent peroxide reductase, mitochondrial Thioredoxin	A0A3Q1LMV5 A0A3Q1M7E3 A0A3Q1MKI4 A0A3Q1MTW8 A0A452DHY1 A0A452DHY4 A5PJN2 A6QLY2 E1BE86 E1BHL1 E1BKZ1 F1MCF5 F1MNQ4 F1MQX5 F6PZE4 F6Q9Q9 F6R4N7 O46521 O46522 O62768 O77834 O97680 P00432 P00435 P00442 P35705 P37141 P62894 Q29RJ1 Q2NL01 Q5E947 Q95108 Q9BGI1 Q9BGI3 Q9N2I8	AOP1 AOP2 CAT CCS CYBA CYBB CYC CYCS ERO1A ERO1L GPX GPX1 GPX3 GPX5 GPX7 GPX8 GSR GSTP1 NCF1 NCF2 NCF4 NOX4 NOX5 NUDT2 P4HB PHGPX PRDX1 PRDX2 PRDX3 PRDX5 PRDX6 SOD1 SOD2 SOD3 TRXR2 TXN TXN2 TXNRD1 TXNRD2	Bos taurus (cattle)
G alpha (12/13) signalling events	A-kinase anchoring protein 13 Active breakpoint cluster region-related protein Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor FGD1 family, member 3 FGD1 protein FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 4 G protein subunit alpha 12 G protein subunit alpha 13 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Intersectin 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G5 Plexin B1 Proto-oncogene vav Rac/Cdc42 guanine nucleotide exchange factor 6 Ras protein specific guanine nucleotide releasing factor 2 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 33 Rho guanine nucleotide exchange factor 37 Rho guanine nucleotide exchange factor 38 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rho/Rac guanine nucleotide exchange factor 18 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 TIAM Rac1 associated GEF 2 Thromboxane A2 receptor Transforming protein RhoA Tyrosine-protein kinase Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A3Q1LFQ5 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUW4 A0A3Q1LXW7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA22 A0A3Q1MA88 A0A3Q1MA97 A0A3Q1MAT2 A0A3Q1MD11 A0A3Q1MIT6 A0A3Q1MN47 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N5H1 A0A3Q1N6F4 A0A3Q1NGS8 A0A3S5ZPL0 A4IFL6 A5D7I5 A5PKD6 A6QNS3 E1B7F6 E1B7M1 E1B7W0 E1B8Q3 E1B9G8 E1BBD2 E1BDY4 E1BH05 E1BIL1 E1BIM5 E1BKY4 E1BP14 E1BQ24 F1MBM9 F1MF50 F1MGA6 F1MJ96 F1MLS2 F1MM93 F1MPJ6 F1MSU8 F1MYW8 F1N0Q1 F1N1J9 F1N1Q7 F1N2G5 F1N7C3 G5E6P3 P02698 P11017 P30671 P50154 P61585 P62871 P63212 P63214 P63217 Q08DA6 Q08DN7 Q0P5E3 Q1RMJ6 Q28024 Q3SZ98 Q3ZC95 Q58CS5 Q5E9F0 Q95125	ABR ADRA1A ADRA1B ADRA1D AKAP13 ARHA ARHC ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF26 ARHGEF3 ARHGEF33 ARHGEF37 ARHGEF38 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BTK FGD1 FGD2 FGD3 FGD4 GNA12 GNA13 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 ITSN1 L2HGDH MCF2L NET1 NGEF PLEKHG2 PLEKHG5 PLXNB1 PREX1 RASGRF2 RHO12 RHOA RHOC ROCK1 ROCK2 SOS1 SOS2 TBXA2R TIAM2 TRIO VAV1 VAV2 VAV3	Bos taurus (cattle)
Glycerophospholipid catabolism	Glycerophosphocholine choline phosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	E1BMJ5 F1N5C8 Q3T0T0	ENPP6 GDE1 MIR16 PNPLA6	Bos taurus (cattle)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	F1MGG8 F1MJE0 F1MYE0 G1K218 P07455 P07456	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Bos taurus (cattle)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 FAD synthase Riboflavin transporter Solute carrier family 52, riboflavin transporter, member 3 Tartrate-resistant acid phosphatase type 5 riboflavin kinase	A0A3Q1MPJ2 A0A3Q1N6I5 E1B8A0 F1MNS5 F6R223 Q5E9R1	ACP5 ENPP1 FLAD1 RFK RFT2 SLC52A2 SLC52A3	Bos taurus (cattle)
Rhesus glycoproteins mediate ammonium transport.	Ammonium transporter Rh type A Ammonium transporter Rh type B Ammonium transporter Rh type C	A0A3Q1M0T1 F1MKX8 Q95M77	RHAG RHBG RHCG	Bos taurus (cattle)
Adenylate cyclase inhibitory pathway	Adenylate cyclase type 1 Adenylate cyclase type 2 Adenylate cyclase type 3 Adenylate cyclase type 4 Adenylate cyclase type 5 Adenylate cyclase type 6 Adenylate cyclase type 8 G protein subunit alpha L Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein G(t) subunit alpha-3 adenylate cyclase	A0A3Q1M3D6 A0A3Q1MA58 A7MBH9 E1B9K3 E1BHU9 E1BM79 E1BQ12 F1MJV4 F1MPC9 P0C7Q4 P19754 P63097 Q3ZCA7	ADCY1 ADCY2 ADCY3 ADCY4 ADCY5 ADCY6 ADCY8 ADCY9 GNAI1 GNAI2 GNAI3 GNAL GNAT3	Bos taurus (cattle)
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Checkpoint kinase 2 M-phase inducer phosphatase 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A452DI44 A0A452DIY4 A7MBA2 A7MBD1 E1BD83 F1MBI1 F1MLV1 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 F6R5E4 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CDC25A CHEK2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
TP53 Regulates Transcription of Death Receptors and Ligands	Insulin-like growth factor-binding protein 3 receptor Insulin-like growth factor-binding protein 3	P20959 Q1JQE1	IGFBP3 TMEM219	Bos taurus (cattle)
Role of phospholipids in phagocytosis	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma 5'-3' exonuclease PLD3 Fc fragment of IgG receptor IIb Fc fragment of IgG receptor Ia Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Immunoglobulin V-set domain-containing protein Low affinity immunoglobulin gamma Fc region receptor III-A Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phospholipase D family member 4 Phospholipase Phospholipase Phospholipid phosphatase 4 Phospholipid phosphatase 5 Protein kinase C delta type T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phospholipase A2	A0A3Q1LJY0 A0A3Q1LKV0 A0A3Q1LPG0 A0A3Q1M3L6 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MHG9 A0A3Q1MMD9 A0A3Q1MRR6 A0A3S5ZP99 E1BB89 F1MH11 F1MHH9 F1MXQ6 F1MYF9 F1MYM3 G3N0V0 G8JL01 P23726 P23727 P32871 P79107 Q0VCU4 Q2KJJ8	CD247 CD3G FCGR1A FCGR2B FCGR3 FCGR3A FCGRIII PIK3CA PIK3CB PIK3R1 PIK3R2 PLA2G6 PLCG1 PLCG2 PLD1 PLD2 PLD3 PLD4 PLPP4 PLPP5 PRKCD SYK	Bos taurus (cattle)
Stabilization of p53	Cellular tumor antigen p53 Checkpoint kinase 2 E3 ubiquitin-protein ligase Mdm2 Serine-protein kinase ATM	E1BEI6 F1MYE6 F6R5E4 P67939	ATM CHEK2 MDM2 TP53	Bos taurus (cattle)
Adrenaline signalling through Alpha-2 adrenergic receptor	Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor	A0A3Q1LQ48 G3X6S2 Q28838	ADRA2A ADRA2B ADRA2C	Bos taurus (cattle)
Metabolism of steroid hormones	Steroid sulfatase	A0A3Q1LZ44	STS	Bos taurus (cattle)
Maturation of TCA enzymes and regulation of TCA cycle	Acetyl-CoA acetyltransferase, mitochondrial Aconitate hydratase, mitochondrial Citrate synthase lysine methyltransferase Citrate synthase, mitochondrial Frataxin, mitochondrial Iron-sulfur cluster assembly 1 homolog, mitochondrial Iron-sulfur cluster assembly 2 homolog, mitochondrial Iron-sulfur cluster assembly enzyme Isocitrate dehydrogenase [NADP], mitochondrial LYR motif-containing protein 4 NAD-dependent protein deacetylase Succinate dehydrogenase [ubiquinone] cytochrome b small subunit Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase assembly factor 1, mitochondrial Succinate dehydrogenase assembly factor 2, mitochondrial Succinate dehydrogenase assembly factor 3, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial Succinate dehydrogenase cytochrome b560 subunit, mitochondrial cysteine desulfurase	A0A3Q1LZ07 A0A3Q1M728 A5PKG4 A8PU71 E1BE08 G5E521 G5E6M7 P20004 P35720 Q04467 Q05B87 Q0P574 Q0VCG0 Q17QE6 Q29RK1 Q29RZ0 Q2TBG7 Q3SZG8 Q3ZBC2 V6F7N8	ACAT1 ACN9 ACO2 CS CSKMT CYB560 FRDA FXN HBLD1 HBLD2 IDH2 ISCA1 ISCA2 ISCU ISD11 LYRM4 LYRM8 NFS1 PGL2 SDH5 SDHA SDHAF1 SDHAF2 SDHAF3 SDHB SDHC SDHD SIRT3	Bos taurus (cattle)
Miscellaneous transport and binding events	ANKH inorganic pyrophosphate transport regulator Adducin 1 Adducin 2 Adducin 3 Alpha-2-glycoprotein 1, zinc-binding Cystinosin Dematin LRRC8D protein Leucine rich repeat containing 8 VRAC subunit A Leucine rich repeat containing 8 VRAC subunit B Magnesium transporter NIPA2 Magnesium transporter protein 1 Magnesium transporter NIPA like domain containing 1 NIPA like domain containing 2 NIPA like domain containing 3 NIPA like domain containing 4 NIPA magnesium transporter 1 Prolactin-induced protein Prolactin-inducible protein homolog Solute carrier family 66 member 1 Tumor suppressor candidate 3 Volume-regulated anion channel subunit LRRC8C Volume-regulated anion channel subunit LRRC8E	A0A3Q1N598 A0A3Q1NDE1 A0A452DK44 A4IFE5 A5PK13 A6QR45 A7MB63 E1BD04 E1BDX2 E1BDX3 E1BHG8 E1BHK2 E1BLE7 F1MAW1 F1MCV8 F1MFE0 F1MII2 F1MXA4 F1N136 F6PRJ0 G3MY77 Q08DM1 Q08E42 Q3SWX0	ADD1 ADD2 ADD3 ANKH AZGP1 CTNS DMT DMTN EPB49 LLRC8A LOC104972276 LRRC8A LRRC8B LRRC8C LRRC8D LRRC8E MAGT1 MRS2 NIPA1 NIPA2 NIPAL1 NIPAL2 NIPAL3 NIPAL4 PIP SLC66A1 TUSC3	Bos taurus (cattle)
Receptor Mediated Mitophagy	Autophagy protein 5 Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta FUN14 domain-containing protein 1 Microtubule-associated proteins 1A/1B light chain 3A Microtubule-associated proteins 1A/1B light chain 3B Serine/threonine-protein phosphatase PGAM5, mitochondrial Tyrosine-protein kinase Ubiquitin-like protein ATG12 Unc-51 like autophagy activating kinase 1	E1BIE7 E1BIM8 F1MFB2 F1MJ55 F1MZE2 F1N5S9 O41515 P67868 P68399 Q2HJ23 Q3MQ24	ATG12 ATG5 CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B FUNDC1 MAP1ALC3 MAP1LC3 MAP1LC3A MAP1LC3B PGAM5 SRC ULK1	Bos taurus (cattle)
PI-3K cascade:FGFR2	Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GRB2-associated-binding protein 1 Growth factor receptor-bound protein 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Tyrosine-protein phosphatase non-receptor type	A0A3Q1LRU7 A0A3Q1M3Q3 A0A3Q1NAV6 A0MTF4 A6QLU3 D8KXU9 E1B7I9 E1BGY3 E1BHC1 E1BJU2 E1BP37 F1MHC6 F1N339 F1N6G8 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 P23727 P32871 Q3T0F9	AFGF FGF1 FGF10 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF9 FGFA FGFR2 FRS2 Fgf4 GAB1 GRB2 HBGF-1 PIK3CA PIK3R1 PTPN11	Bos taurus (cattle)
Ion channel transport	V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit	A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 E1BGJ7 E1BMV6 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q28029 Q2KJB6 Q2TA24 Q32LB7	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H LOC101904667 TCIRG1 VATC VATF VPATPD	Bos taurus (cattle)
Insulin receptor recycling	Cathepsin D Insulin-degrading enzyme Insulin Receptor-type tyrosine-protein phosphatase F Tyrosine-protein kinase receptor Tyrosine-protein phosphatase non-receptor type V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit S1 V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit	A0A3Q1MS24 A0A452DI38 A0A452DJ67 A4IFJ9 A5PJB2 A6QQN2 A7MBJ4 E1BGJ7 E1BMV6 F1MMR6 F1MV64 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P40682 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q24K02 Q28029 Q2KJB6 Q2TA24 Q32LB7	ATP6A1 ATP6AP1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6IP1 ATP6N1B ATP6S1 ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CTSD IDE INS INSR LOC101904667 PTPN1 PTPRF TCIRG1 VATC VATF VPATPD	Bos taurus (cattle)
Ion transport by P-type ATPases	ATPase 13A1 ATPase cation transporting 13A2 Calcium-transporting ATPase type 2C member 1 Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like Cardiac phospholamban Cation-transporting ATPase Cation-transporting ATPase EF-hand domain-containing protein FXYD domain-containing ion transport regulator 6 FXYD domain-containing ion transport regulator 7 FXYD domain-containing ion transport regulator FXYD domain-containing ion transport regulator P-type Ca(2+) transporter Phospholemman Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Phospholipid-transporting ATPase Plasma membrane calcium-transporting ATPase 4 Probable phospholipid-transporting ATPase IIB Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 Sodium/potassium-transporting ATPase subunit alpha-1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit alpha Sodium/potassium-transporting ATPase subunit beta-3 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Sorcin calcium/calmodulin-dependent protein kinase	A0A3Q1LHA5 A0A3Q1LQ26 A0A3Q1LWV7 A0A3Q1LYD6 A0A3Q1M082 A0A3Q1M0A4 A0A3Q1M1C8 A0A3Q1M288 A0A3Q1M9U0 A0A3Q1MCF3 A0A3Q1MGH8 A0A3Q1MKC7 A0A3Q1MR28 A0A3Q1ND98 A1A4J6 A2VDL6 A6QLL5 D3K0R6 E1B8N5 E1BLX8 E1BMQ6 E1BNB9 E1BPC3 F1MF00 F1MFC4 F1MLH6 F1MMX5 F1MN60 F1MR06 F1MS16 F1MW32 F1MXW4 F1MYA8 F1MZ89 F1N272 F1N3G6 F1N7C2 F2Z4I4 F6QQY9 G3MWR4 P57709 Q08DA1 Q0VCY0 Q2HJF7 Q3MHJ9 Q3MHZ5 Q3SZX0 Q3T0C6 Q3ZBJ3	ATP10A ATP10B ATP10D ATP11A ATP11B ATP11C ATP12A ATP13A1 ATP13A2 ATP13A4 ATP13A5 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 ATP2C1 ATP2C2 ATP4A ATP4B ATP8A1 ATP8A2 ATP8B1 ATP8B2 ATP8B3 ATP8B4 ATP9A ATP9B CALM CAMK2A CAMK2B CAMK2D FXYD1 FXYD2 FXYD4 FXYD6 FXYD7 PLM PLN SPCA SRI	Bos taurus (cattle)
GABA B receptor activation	Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2	F1MF15 F1MIZ5	GABBR1 GABBR2	Bos taurus (cattle)
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits	ATP-sensitive inward rectifier potassium channel 12 G protein subunit beta 3 G protein subunit gamma 13 G protein-activated inward rectifier potassium channel 1 G protein-activated inward rectifier potassium channel 2 G protein-activated inward rectifier potassium channel 4 GNB4 protein Gamma-aminobutyric acid type B receptor subunit 1 Gamma-aminobutyric acid type B receptor subunit 2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Inward rectifier potassium channel 2 KCNJ10 protein KCNJ15 protein Potassium inwardly rectifying channel subfamily J member 16 Potassium inwardly rectifying channel subfamily J member 4	A0A3Q1M4V6 A0A3Q1NGS8 A0A3S5ZPL0 A2VDQ4 A4IFL6 A5PJL2 A5PKD6 E1B8Q3 E1BNE9 F1MF15 F1MIZ5 F1MUD1 F1MYR9 F1MYW8 O19182 P02698 P11017 P30671 P50154 P62871 P63212 P63214 P63217 Q0VD28 Q28024 Q3SZ98 Q4TZY1 Q5E9F0	GABBR1 GABBR2 GIRK1 GIRK4 GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 IRK1 KCNJ10 KCNJ12 KCNJ15 KCNJ16 KCNJ2 KCNJ3 KCNJ4 KCNJ5 KCNJ6	Bos taurus (cattle)
GLI3 is processed to GLI3R by the proteasome	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase I isoform alpha Cullin 1 GLI family zinc finger 3 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase	A0A3Q1MDV1 A0A452DI44 A0A452DIY4 A0A452DJE2 A7MBA2 E1BD83 F1MBI1 F1MIC3 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N215 F1N6Z0 G5E589 P00517 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 P67827 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CSNK1A1 CUL1 GLI3 GSK3B PRKACA PRKACB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SKP1 SKP1A SUFU SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Molecules associated with elastic fibres	Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphotic protein 10 Bone morphotic protein 7 EGF containing fibulin extracellular matrix protein 2 Fibulin-5 Growth differentiation factor 5 Integrin beta-6 Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 2 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Microfibril associated protein 3 Microfibril associated protein 5 Microfibril-associated glycoprotein 4 Transforming growth factor beta-1 proprotein Transforming growth factor beta-2 proprotein Transforming growth factor beta Vitronectin	A0A140T828 A0A140T8D2 A0A3Q1LJU9 A0A3Q1M1V6 A0A3Q1MN12 A0A3Q1MXS2 A0A3Q1N449 A5PJI9 A6QP91 E1B8X7 F1MF86 F1MGZ1 F1MLT0 F1MT44 F1MTN1 F1MVW3 F1N444 G3MZT8 P21214 P55918 Q2KJH1 Q3ZBS7 Q8SQB8 Q8SQB9	BMP10 BMP2 BMP4 BMP7 EFEMP2 FBLN5 GDF5 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP2 LTBP3 LTBP4 MFAP3 MFAP4 MFAP5 TGFB1 TGFB2 TGFB3 VTN	Bos taurus (cattle)
The canonical retinoid cycle in rods (twilight vision)	Cytochrome P450 family 4 subfamily V member 2 Cytosolic fatty-acid binding proteins domain-containing protein Dehydrogenase/reductase SDR family member 9 Hydroxysteroid (17-beta) dehydrogenase 6 Lecithin retinol acyltransferase Microsomal NAD+-dependent retinol dehydrogenase 4 Myosin VIIA Plasma retinol-binding protein Receptor for retinol uptake STRA6 Retinal-specific phospholipid-transporting ATPase ABCA4 Retinaldehyde-binding protein 1 Retinol binding protein 1 Retinol binding protein 3 Retinol dehydrogenase 10 Retinol dehydrogenase 11 Retinol dehydrogenase 12 Retinol dehydrogenase 5 Rhodopsin Short-chain dehydrogenase/reductase family 9C member 7 Transthyretin	A0A3Q1LG56 A0A3Q1LU75 A0A3Q1MJ64 A0A3Q1MSW9 A0A452DJ95 A4IFM3 E1BM93 F1MD39 F1MG20 F1MLW4 F1MWM0 F1N3Z7 F6RLW9 O46375 P02699 P10123 Q0V8D0 Q27979 Q8HYR6 Q8HZT6	ABCA4 ABCR CRALBP CYP4V2 DHRS9 HSD17B6 LOC101906939 LRAT MYO7A RBP1 RBP3 RBP4 RDH1 RDH10 RDH11 RDH12 RDH16 RDH5 RDHS RHO RLBP1 SDR9C7 SDRO STRA6 TTR	Bos taurus (cattle)

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