GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **126 - 150** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Effects of PIP2 hydrolysis	Diacylglycerol kinase alpha Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Diacylglycerol kinase Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Protein kinase C delta type Protein kinase C eta type Protein kinase C Short transient receptor potential channel 6 Transient receptor potential cation channel subfamily C member 3 Transient receptor potential cation channel subfamily C member 7	A0A3Q1LTG6 A0A3Q1M4W2 A0A3Q1MRR6 A0A3Q1N4W0 A0A3Q1N7P8 A0A3Q1NJA6 A0JN54 E1B7K6 E1B7U7 E1BGA9 E1BKE7 E1BMG4 F1MCG9 F1MX21 F1MY82 G5E5G8 Q9MYW0	DGKA DGKB DGKD DGKE DGKI DGKK DGKQ DGKZ ITPR1 ITPR2 ITPR3 PRKCD PRKCH PRKCQ TRP6 TRPC3 TRPC6 TRPC7	Bos taurus (cattle)
Hedgehog ligand biogenesis	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Derlin Endoplasmic reticulum lectin Endoplasmic reticulum lectin Hedgehog acyltransferase Hedgehog protein Hedgehog protein Hedgehog protein Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein disulfide-isomerase RING-type E3 ubiquitin transferase SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1NEJ8 A0A452DI44 A0A452DIY4 A7MBA2 E1BAK9 E1BD83 F1MBI1 F1MFP2 F1MGJ5 F1MGK3 F1MLV1 F1MM97 F1MWE0 F1MX65 F1MXE4 F1MYH8 F1N6Z0 F6PVF9 F6Q9Q9 F6QA78 G3X757 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	DERL2 DHH ERLEC1 HHAT IHH OS9 P4HB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SEL1L SHH SUG1 SYVN1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 VCP	Bos taurus (cattle)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Deoxyribose-phosphate aldolase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase ribose-5-phosphate isomerase	A0A3Q1MM55 A0A3S5ZPM3 A0A3S5ZPP1 A5D7P1 A7Z014 E1BJH7 F1MM83 F6QEU6 G5E534 G5E5C8 Q3T0V9	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT	Bos taurus (cattle)	G31080DL
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK protein Transcription factor AP-2-alpha	A1A4R9 A5PJQ1	DEK TFAP2A	Bos taurus (cattle)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production	ATP-dependent DNA/RNA helicase DHX36 ATP-dependent RNA helicase A Myeloid differentiation primary response protein MyD88 NF-kappaB transcription factor p65 subunit NFKB2 protein Nuclear factor NF-kappa-B p105 subunit	A0A452DHW6 A1XG22 A7MBB7 F1MKW9 Q05B79 Q28141	DDX9 DHX36 DHX9 MYD88 NDH2 NFKB1 NFKB2 RELA	Bos taurus (cattle)
Non-integrin membrane-ECM interactions	Tyrosine-protein kinase receptor receptor protein-tyrosine kinase	E1BBP4 F1MIE0	DDR1 DDR2	Bos taurus (cattle)
Dopamine receptors	D(1A) dopamine receptor D(1B) dopamine receptor D(2) dopamine receptor D(3) dopamine receptor	F1N454 F1N4I3 G3X8D2 Q95136	D1AR DRD1 DRD2 DRD3 DRD5	Bos taurus (cattle)
Leukotriene receptors	CYSLTR2 protein Cysteinyl leukotriene receptor 1 G protein-coupled receptor 17 Leukotriene B4 receptor 1 Leukotriene B4 receptor 2	A2VEA2 A5PKG3 A7MBH4 F1MRY8 Q3T181	CYSLTR1 CYSLTR2 GPR17 LTB4R LTB4R2	Bos taurus (cattle)
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein S100-A8 Protein S100-A9 Protein kinase C beta type Protein kinase C delta type Protein kinase C Ras-related C3 botulinum toxin substrate 2 mitogen-activated protein kinase non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1LTT9 A0A3Q1MKI4 A0A3Q1MRR6 A0A3Q1MSP9 A0A3Q1MTW8 A0A452DHY1 A6QLW1 E1B8P9 E1BAA4 E1BFF3 E1BPJ7 F1MHS5 G3X793 O46521 O46522 P05126 P28782 P46196 Q5BIN5 Q9TU25	CYBA CYBB ERK2 MAPK1 MAPK11 MAPK14 MAPK3 NCF1 NCF2 NCF4 NOX1 NOX3 NOXO1 PIK3C3 PIK3R4 PIN1 PRKCB PRKCB1 PRKCD PRKCZ PRKM1 RAC2 S100A8 S100A9	Bos taurus (cattle)
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glutathione S-transferase omega Glutathione-dependent dehydroascorbate reductase NADH-cytochrome b5 reductase 3 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 23 member 1 Solute carrier family 23 member 2	A2VDL2 E1BED9 E1BI45 E1BJ08 E1BP61 P00171 P07514 P27674	CYB5 CYB5A CYB5R3 DIA1 GLUT1 GSTO2 SLC23A1 SLC23A2 SLC2A1 SLC2A3	Bos taurus (cattle)
Signaling by ROBO receptors	C-X-C chemokine receptor type 4 Glypican-1 Roundabout guidance receptor 1 Slit guidance ligand 2 Slit guidance ligand 3 Stromal cell-derived factor 1	A0A3Q1LZ29 A0A3Q1M085 F1MLJ7 F1MMM6 F1N739 P25930	CXCL12 CXCR4 GPC1 ROBO1 SLIT2 SLIT3	Bos taurus (cattle)
KEAP1-NFE2L2 pathway	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 3 E3 ubiquitin-protein ligase TRIM21 Kelch-like ECH-associated protein 1 Microtubule-associated proteins 1A/1B light chain 3B NFE2 like bZIP transcription factor 2 NPL4 homolog, ubiquitin recognition factor Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein kinase C RING-type E3 ubiquitin transferase SESN1 protein Sequestosome 1 Sestrin-2 Transitional endoplasmic reticulum ATPase UBX domain-containing protein 7 Ubiquitin recognition factor in ER associated degradation 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LRK0 A0A3Q1LVE4 A0A3Q1N3E8 A0A452DI44 A0A452DIY4 A7MBA2 A7MBG4 A7MBI2 E1BD83 E1BGD5 E1BIN5 F1MBI1 F1MLV1 F1MQ96 F1MUA8 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 F1N7U2 G3X757 G5E589 O41515 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58CN8 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0 Q7YRV4	CUL3 KEAP1 MAP1ALC3 MAP1LC3 MAP1LC3B MUL1 NFE2L2 NPLOC4 PRKCI PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SESN1 SESN2 SQSTM1 SUG1 TRAP2 TRIM21 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBXN7 UFD1 VCP	Bos taurus (cattle)
Degradation of DVL	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 3 Dishevelled binding antagonist of beta catenin 1 Dishevelled segment polarity protein 1 Dishevelled segment polarity protein 2 Dishevelled segment polarity protein 3 HECT-type E3 ubiquitin transferase Kelch like family member 12 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1MSZ4 A0A452DI44 A0A452DIY4 A0A452DJ83 A7MBA2 E1BD83 E1BIN5 F1MBI1 F1MLV1 F1MMW6 F1MP88 F1MWE0 F1MXE4 F1MYH8 F1N0L0 F1N6M9 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CUL3 DACT1 DVL1 DVL2 DVL3 HECW1 KLHL12 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Regulation of RUNX2 expression and activity	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 E3 ubiquitin-protein ligase CHIP Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Runt-related transcription factor S-phase kinase-associated protein 1 SKP2 protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1MKY5 A0A452DI44 A7MB09 A7MBA2 E1B7G3 F1MBI1 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CUL1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSMF1 RPS27A RUNX2 SKP1 SKP1A SKP2 STUB1 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 Glycogen synthase kinase-3 beta NFE2 like bZIP transcription factor 2 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta S-phase kinase-associated protein 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1LRK0 A0A452DI44 A7MBA2 F1MBI1 F1MIC3 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CUL1 GSK3B NFE2L2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSMF1 RPS27A SKP1 SKP1A SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Degradation of GLI1 by the proteasome	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Cullin 1 E3 ubiquitin-protein ligase GLI family zinc finger 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Protein numb homolog S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1MDV1 A0A452DI44 A0A452DIY4 A6H727 A7MBA2 E1B8G1 E1BD83 F1MBI1 F1MGQ5 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N6Z0 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CUL1 GLI1 ITCH NUMB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SKP1 SKP1A SUFU SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Procathepsin L Serpin family B member 13	E1BIP8 P25975 Q5E968	CTSK CTSL CTSL1 SERPINB13	Bos taurus (cattle)
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin Excitatory amino acid transporter 1 Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A3Q1MR13 A6H774 A6QR09 A7MB63 F1MJN4 F1MUT8 G3N354 P46411	CTNS EAAT1 GLAST GLAST1 SAMC SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1	Bos taurus (cattle)
RUNX3 regulates WNT signaling	Catenin beta-1 Lymphoid enhancer binding factor 1 Runt-related transcription factor Transcription factor 7 like 1 Transcription factor 7 like 2 Transcription factor 7	A0A3Q1MAN6 A0A3Q1MG64 A0A3Q1MYL2 A0A3Q1MZ99 F1MJS2 Q0VCX4	CTNNB1 LEF1 RUNX3 TCF7 TCF7L1 TCF7L2	Bos taurus (cattle)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 2 Choline transporter-like protein 3 Choline transporter-like protein 4 Choline transporter-like protein Choline transporter-like protein Multidrug and toxin extrusion protein Solute carrier family 10 member 6 Solute carrier family 14 member 2 Solute carrier family 5 (Choline transporter), member 7 Urea transporter 1	A0A3Q1MWZ9 A0A452DJI9 A3KMY4 A5D7H3 A5PK40 E1BIP2 E1BP25 F1N5M4 Q2KI26 Q5QF96	CTL2 CTL3 CTL4 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC44A5 SLC47A2 SLC5A7 TPPT1 UT-B	Bos taurus (cattle)
GLI3 is processed to GLI3R by the proteasome	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase I isoform alpha Cullin 1 GLI family zinc finger 3 Glycogen synthase kinase-3 beta Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta S-phase kinase-associated protein 1 Suppressor of fused homolog Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase	A0A3Q1MDV1 A0A452DI44 A0A452DIY4 A0A452DJE2 A7MBA2 E1BD83 F1MBI1 F1MIC3 F1MLV1 F1MWE0 F1MXE4 F1MYD0 F1MYH8 F1N215 F1N6Z0 G5E589 P00517 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 P67827 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF3 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CSNK1A1 CUL1 GLI3 GSK3B PRKACA PRKACB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RPS27A SKP1 SKP1A SUFU SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Signaling by CSF3 (G-CSF)	Colony stimulating factor 3 receptor GRB2 associated binding protein 2 Granulocyte colony-stimulating factor Growth factor receptor-bound protein 2 SHC-transforming protein 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1M864 A0A3Q1MHG9 A0A3Q1MYA3 E1B9W2 E1BCP6 E1BMX0 F1MCX4 F1N0D6 F1N261 F1N339 P35833 Q0IIE2 Q3T0F9	CSF3 CSF3R GAB2 GCSF GRB2 JAK1 JAK2 KRAS LYN PTPN11 SHC1 SRC SYK TYK2	Bos taurus (cattle)
Inactivation of CSF3 (G-CSF) signaling	Colony stimulating factor 3 receptor Cullin-5 Elongin-C Granulocyte colony-stimulating factor Polyubiquitin-B Polyubiquitin-C Ring finger protein 7 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M5N0 A0A3Q1MHG9 A0A3Q1MXH0 A0A3Q1MYA3 E1B9W2 E1BCP6 F1MCX4 F1MSN0 F1N0D6 F1N261 P0CG53 P0CH28 P35833 P62992 P63048 Q0P5F4 Q1RMX2 Q2KII4 Q2TA10 Q3SZ32 Q9BEG9	CSF3 CSF3R CUL5 ELOC GCSF JAK1 JAK2 LYN RNF7 RPS27A SOCS1 SOCS3 SRC SYK TCEB1 TCEB2 TYK2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 UBE2D3	Bos taurus (cattle)
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Granulocyte-macrophage colony-stimulating factor Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-3 Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene vav SHC-transforming protein 1 Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A140T878 A0A3Q1LK34 A0A3Q1M739 E1BCP6 E1BE66 F1MDQ5 F1MH16 F1MSH3 F1MXH7 F1MYM3 F1N339 P00517 P11052 P23726 P23727 P32871 P49875 P52173 P63103 Q08DN7 Q0IIE2 Q95115	CSF2 CSF2RB IL3 IL3RA IL5 IL5RA JAK2 MGF PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PRKACA PTPN11 PTPN6 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ	Bos taurus (cattle)
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LJT8 A0A3Q1LK34 A0A3Q1M739 A0A3Q1M864 A2VE30 E1BBJ7 E1BCP6 E1BE66 E1BEL4 F1MDQ5 F1MH16 F1MXH7 F1MYM3 F1N0D6 F1N7C3 P05016 P11052 P23726 P23727 P32871 P49875 P52173 Q0IIE2 Q3T0F9 Q95118	CSF2 CSF2RB GAB2 GRB2 IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PTPN6 SHC1 SOS1	Bos taurus (cattle)

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