GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **557** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase Tyrosine-protein kinase	E1BCP6 F1MEQ7 F1MJE0 F1N261	EPOR IRS2 JAK2 LYN	Bos taurus (cattle)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein non-specific serine/threonine protein kinase	A2VE07 Q2KIA5 Q2LGB8 Q5E9F1	BCAP31 CASP8 DNM1L STK24	Bos taurus (cattle)
Regulation of PTEN stability and activity	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta E3 ubiquitin-protein ligase CHIP E3 ubiquitin-protein ligase RNF146-B E3 ubiquitin-protein ligase XIAP E3 ubiquitin-protein ligase HECT-type E3 ubiquitin transferase Phosphatase and tensin homolog Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Poly [ADP-ribose] polymerase Poly [ADP-ribose] polymerase Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase Tyrosine-protein kinase Ubiquitin carboxyl-terminal hydrolase 13 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein ubiquitinyl hydrolase 1	A0A3Q1M230 A0A3Q1MXC6 A0A452DI44 A0A452DIY4 A7MBA2 E1B7G3 E1B8R5 E1BD83 E1BDL7 E1BDM3 E1BMF7 E1BPI3 F1MBI1 F1MDX9 F1MF12 F1MJ10 F1MJ55 F1MLV1 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 G3MWG5 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 P67868 P68399 Q17QP9 Q1LZA9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3T139 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B FRK MKRN1 NEDD4 OTUD3 PREX2 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN RNF146B RPS27A STUB1 SUG1 TNKS TNKS2 TRAP2 TRIM27 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 USP13 WWP2 XIAP	Bos taurus (cattle)
FRS-mediated FGFR3 signaling	FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase NRas Growth factor receptor-bound protein 2 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A3Q1MPT9 A0MTF4 A5D7R9 A6H792 D8KXU9 E1B7I9 E1BJU2 E1BMX0 E1BP37 F1MHC6 F1N339 F1N6G8 F1N7C3 F2Z4J0 G3MXR4 G3XGD3 P03968 P03969 Q3T0F9	AFGF FGF1 FGF16 FGF17 FGF18 FGF2 FGF20 FGF23 FGF4 FGF4A FGF4C FGF5 FGF6A FGF8 FGF9 FGFA FGFR3 FRS2 FRS3 Fgf4 GRB2 HBGF-1 KRAS NRAS PTPN11 SOS1	Bos taurus (cattle)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	G1K218 P07455 P07456	IGF1 IGF1R IGF2	Bos taurus (cattle)
VEGFA-VEGFR2 Pathway	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Adapter molecule crk BAR/IMD domain-containing adapter protein 2 BCAR1 scaffold protein, Cas family member C22H3ORF10 protein Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein Cytoplasmic protein Cytoplasmic protein Dedicator of cytokinesis 1 Engulfment and cell motility 2 Focal adhesion kinase 1 Heat shock protein HSP 90-alpha Heat shock protein beta-1 Integrin beta Integrin subunit alpha V MAP kinase-activated protein kinase 3 MAPK activated protein kinase 2 Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 13 NCK associated protein 1 like Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Paxillin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Proto-oncogene vav Rho-associated protein kinase SH2 domain containing adaptor protein B SH2D2A protein SHC adaptor protein 2 Transforming protein RhoA Tyrosine-protein kinase Fyn Tyrosine-protein kinase Vascular endothelial growth factor A Vascular endothelial growth factor receptor 2 Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase mitogen-activated protein kinase non-specific protein-tyrosine kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase	A0A3Q1LTT9 A0A3Q1LVP1 A0A3Q1M0G8 A0A3Q1M614 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MQ07 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRN2 A0A3Q1MTW8 A0A3Q1MW77 A0A3Q1MXS2 A0A3Q1N508 A0A3Q1NMX4 A0A452DHY1 A0A452DJE2 A0JNB0 A2VDK6 A6H720 A7Z041 A8YXX8 E1B876 E1BBD2 E1BIM8 E1BLY9 E1BN47 E1BPY0 E1BQ32 F1MF50 F1MFD1 F1MIX6 F1MTN1 F1MWF1 F1MX60 F1MYM3 F1N5N3 G3X793 O46521 O46522 P00517 P15691 P23726 P23727 P32871 P61585 Q08DN7 Q0IIJ3 Q1LZB2 Q2KJ93 Q3SYZ2 Q3T149 Q5E9Q6 Q5EAD0 Q76LV2	ABI1 ABI2 ARHA AXL BAIAP2 BCAR1 BRK1 C22H3ORF10 CDC42 CRK CYBA CYBB CYFIP1 CYFIP2 DOCK1 ELMO2 FYN HSP27 HSP90A HSP90AA1 HSPB1 HSPCA ITGAV ITGB3 KDR MAPK11 MAPK13 MAPK14 MAPKAPK2 MAPKAPK3 NCF1 NCF2 NCF4 NCK1 NCK2 NCKAP1L PAK2 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKACA PRKACB PTK2 PTK2B PXN RHO12 RHOA ROCK1 ROCK2 SH2D2A SHB SHC2 SRC VAV1 VAV2 VAV3 VEGF VEGFA WASF1 WASF2 WASF3	Bos taurus (cattle)
Inactivation of CSF3 (G-CSF) signaling	Colony stimulating factor 3 receptor Cullin-5 Elongin-C Granulocyte colony-stimulating factor Polyubiquitin-B Polyubiquitin-C Ring finger protein 7 Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin conjugating enzyme E2 D3 Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 D2 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M5N0 A0A3Q1MHG9 A0A3Q1MXH0 A0A3Q1MYA3 E1B9W2 E1BCP6 F1MCX4 F1MSN0 F1N0D6 F1N261 P0CG53 P0CH28 P35833 P62992 P63048 Q0P5F4 Q1RMX2 Q2KII4 Q2TA10 Q3SZ32 Q9BEG9	CSF3 CSF3R CUL5 ELOC GCSF JAK1 JAK2 LYN RNF7 RPS27A SOCS1 SOCS3 SRC SYK TCEB1 TCEB2 TYK2 UBA52 UBA80 UBB UBC UBC4 UBCEP1 UBCEP2 UBCH4 UBCH5B UBE2D1 UBE2D2 UBE2D3	Bos taurus (cattle)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Toll-like receptor 9 non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1M5J6 A5H631 A6QLW1	EEA1 PIK3C3 PIK3R4 TLR9	Bos taurus (cattle)
Toll Like Receptor 4 (TLR4) Cascade	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Bactericidal permeability-increasing protein CD180 molecule Dynamin-1 Integrin beta-2 Integrin subunit alpha M Lipopolysaccharide-binding protein Lymphocyte antigen 86 Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 2 Toll-like receptor 4 Tyrosine-protein phosphatase non-receptor type dynamin GTPase	A0A3Q1MIC9 A0A3Q1MMD9 A0A3Q1MZF3 A6QNL0 C4T7Z1 E1BJR7 F1MFI2 F1MNN7 G3MYD9 P17453 P32592 Q08DF4 Q2LGB7 Q6WCD5	BPI CD14 CD18 CD180 DNM1 DNM3 ITGAM ITGB2 LBP LY86 LY96 MD-2 PLCG2 PTPN4 TICAM2 TLR4 TRAM	Bos taurus (cattle)
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 member A2 Aldehyde dehydrogenase family 3 member B1 Alkaline ceramidase Alkaline ceramidase Alkaline ceramidase Phospholipid phosphatase 1 Phospholipid phosphatase 2 Phospholipid phosphatase 3 Sphingosine-1-phosphate phosphatase 1 sphinganine-1-phosphate aldolase	A0A3Q1LJ52 A0A3Q1LM94 A0A3Q1MIK4 A0JNA1 A7MBH7 E1B8N2 F1MGH9 Q1JPA0 Q2HJ61 Q3SZE3	ACER1 ACER2 ACER3 ALDH3A2 ALDH3B1 PLPP1 PLPP2 PLPP3 PPAP2B PPAP2C SGPL1 SGPP1	Bos taurus (cattle)
TRAF6 mediated NF-kB activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Protein S100-A12 Protein S100-B	A0A3Q1LUG2 A0A3Q1LZM4 A1XG22 A7MBB7 F1MKW9 F1N306 P02638 P10103 P79105 Q0IIB2 Q1JPF1 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	AGER APP CAAF1 CHUK HMG1 HMGB1 IKBKB IKBKG IKKA NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA S100A12 S100B bIkBa	Bos taurus (cattle)
Extrinsic Pathway of Fibrin Clot Formation	Coagulation factor IX Coagulation factor VII Coagulation factor X Tissue factor pathway inhibitor Tissue factor	A0A3Q1NLA0 A0A452DIP8 F1MBC5 P22457 P30931	F10 F3 F7 F9 TFPI	Bos taurus (cattle)
Peptide ligand-binding receptors	APLNR protein Adrenocorticotropic hormone receptor Angiotensinogen Apelin Atypical chemokine receptor 1 B1 bradykinin receptor Bombesin receptor subtype-3 C3a anaphylatoxin chemotactic receptor C5L2 C5a anaphylatoxin chemotactic receptor 1 Cholecystokinin Coagulation factor II (Thrombin) receptor-like 2 Complement C3 Complement C5 Cortistatin Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Endothelin-converting enzyme 1 Endothelin-converting enzyme 2 F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 G protein-coupled receptor 37 like 1 G protein-coupled receptor 37 GALR2 protein Galanin peptides Galanin receptor 1 Galanin receptor 3 Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Interleukin-8 KISS1 receptor Kappa-type opioid receptor KiSS-1 metastasis suppressor Kininogen 1 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanocortin receptor 4 Melanocortin receptor 5 Melanocortin-3-receptor Melanocyte-stimulating hormone receptor Motilin receptor Mu-type opioid receptor Neurolysin, mitochondrial Neuromedin B receptor Neuromedin S Neuromedin U receptor 1 Neuromedin U receptor 2 Neuropeptide B Neuropeptide S receptor 1 Neuropeptide S Neuropeptide Y receptor type 1 Neuropeptide Y receptor type 2 Neuropeptide Y receptor type 5 Neuropeptides B and W receptor 1 Neuropeptides B/W receptor type 2 Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Nociceptin receptor Opioid receptor delta 1 Pancreatic polypeptide receptor 1 Pancreatic polypeptide Peptide YY Prepronociceptin Pro-MCH Pro-neuropeptide Y Pro-opiomelanocortin Pro-thyrotropin-releasing hormone Proenkephalin-A Proenkephalin-B Prokineticin 1 Prokineticin 2 Prokineticin receptor 2 Prolactin-releasing peptide receptor Promotilin Prosaposin Proteinase-activated receptor 1 Prothrombin Somatostatin receptor 1 Somatostatin receptor type 2 Somatostatin receptor type 5 Somatostatin Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Type-2 angiotensin II receptor	A0A140T858 A0A140T8C6 A0A140T8C8 A0A3Q1LWC2 A0A3Q1MCT6 A0A3Q1MSN3 A0A3Q1MXN7 A0A3Q1MXY0 A0A452DI66 A0A452DII4 A0A452DIK5 A0A452DJT3 A0A452DKE4 A1Z2Z3 A4IFB7 A4IFF5 A6QL98 A6QLK3 A6QLQ7 A6QM11 A6QQX6 B1H0W3 C3W8S1 E1B8V8 E1B9Q7 E1BCM7 E1BCZ7 E1BFS5 E1BFV6 E1BKZ6 E1BL07 E1BMI3 E1BMN4 F1MCC4 F1MEN6 F1MJD1 F1MJZ0 F1MKB6 F1MMX1 F1MN36 F1MPG4 F1MPN9 F1MV99 F1MWG2 F1MY53 F1MY85 F1N018 F1N083 F1N145 F1N476 F1N4J9 F1N4Y7 F1N5B6 G3N364 G3X795 G5E5J0 G5E6F7 O46639 O62647 P01017 P01156 P01190 P01211 P11242 P17322 P21450 P25104 P28088 P34974 P41520 P42891 P47798 P51694 P56451 P79255 Q08DZ7 Q0VD43 Q1RMU8 Q2KIP6 Q2UVX4 Q4EW11 Q673L2 Q6RUW3 Q863C3 Q867A9 Q8MJV2 Q8MJV4 Q8SPN1 Q9GLJ8	ACKR1 AGT AGTR1 AGTR2 APLN APLNR BDKRB2 BRS3 C3 C3AR1 C5 C5AR1 C5AR2 C5L2 CCK CCKBR CORT CXCL8 ECE1 ECE2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 GAL GALN GALR1 GALR2 GALR3 GPR10 GPR37 GPR37L1 GPR73L1 GPR77 GPR8 GRP GRPR IL8 KISS1 KISS1R KNG1 LOC112445811 MC1R MC2R MC3R MC4R MC5R MCHR1 MCHR2 MLN MLNR MSHR NLN NMBR NMS NMUR1 NMUR2 NPB NPBWR1 NPBWR2 NPS NPSR1 NPY NPY1R NPY2R NPY4R NPY5R NTS NTSR1 NTSR2 OPRD1 OPRK1 OPRL1 OPRM1 PDYN PENK PKR2 PMCH PNOC POMC PPY PPYR1 PRLHR PROK1 PROK2 PROKR2 PSAP PYY SERPINA8 SST SSTR1 SSTR2 SSTR5 TRH TRHR mln	Bos taurus (cattle)
ATF6B (ATF6-beta) activates chaperones	ATF6B protein MBTPS1 protein Membrane-bound transcription factor site-2 protease	A4FUY2 Q08E55 Q0III2	ATF6B MBTPS1 MBTPS2	Bos taurus (cattle)
TAK1-dependent IKK and NF-kappa-B activation	Advanced glycosylation end-product specific receptor Amyloid-beta A4 protein High mobility group protein B1 Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta Protein S100-A12 Protein S100-B	A0A3Q1LUG2 A0A3Q1LZM4 A1XG22 A7MBB7 F1MKW9 F1N306 P02638 P10103 P79105 Q0IIB2 Q1JPF1 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	AGER APP CAAF1 CHUK HMG1 HMGB1 IKBKB IKBKG IKKA NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA S100A12 S100B bIkBa	Bos taurus (cattle)
Triglyceride biosynthesis	2-acylglycerol O-acyltransferase 1 Acyltransferase Alkylglycerol monooxygenase Glycerol kinase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial O-acyltransferase glycerol kinase glycerol kinase phosphatidate phosphatase phosphatidate phosphatase phosphatidate phosphatase	A0A3Q1LKP8 A0A3Q1LV95 E1B9D5 E1BLQ9 F1MDT6 F1MIW3 F1MLW9 F1MSV5 G3MYF6 Q0IID9 Q2NKZ8 Q70VZ7	AGMO DGAT1 GK GK2 GPAM GPAT2 LOC538702 LPIN1 LPIN2 LPIN3 MOGAT1 MOGAT3	Bos taurus (cattle)
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A3Q1LXM0 E1BCP6 F1MCX4 F1MEB5 F1N0D6 F1N0R2 F6Q9Q9 G3MX29 P54349	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 P4HB STAT4 TYK2	Bos taurus (cattle)
Gamma-carboxylation of protein precursors	Coagulation factor IX Coagulation factor VII Coagulation factor X Osteocalcin Prothrombin Vitamin K-dependent gamma-carboxylase Vitamin K-dependent protein C Vitamin K-dependent protein S	A0A3Q1M616 A0A452DI66 A0A452DIP8 A1A4R0 F1MBC5 P07224 P22457 Q07175	BGLAP F10 F2 F7 F9 GC GGCX PROC PROS PROS1	Bos taurus (cattle)
p53-Dependent G1 DNA Damage Response	CDKN1A protein Cyclin E1 Cyclin-A1 Cyclin-A2 Cyclin-dependent kinase 2 Cyclin-dependent kinase inhibitor 1B G1/S-specific cyclin-E2	A5PKM2 A6QLS3 E1B9U2 F1MVR8 G8JKW1 Q5E9K7 Q5E9Y0	CCNA1 CCNA2 CCNE1 CCNE2 CDK2 CDKN1A CDKN1B CDKN2	Bos taurus (cattle)
ADP signalling through P2Y purinoceptor 1	Cytosolic phospholipase A2 G protein subunit beta 3 G protein subunit gamma 13 GNB4 protein Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma P2Y purinoceptor 1 Tyrosine-protein kinase mitogen-activated protein kinase	A0A3Q1LTT9 A0A3Q1NGS8 A0A3S5ZPL0 A4IFJ5 A4IFL6 A5PKD6 E1B8Q3 E1BA29 E1BIM8 F1MYW8 F1N2V3 P02698 P11017 P30671 P38408 P38409 P48042 P50154 P62871 P63212 P63214 P63217 Q28024 Q3SZ98 Q5E9F0	CPLA2 GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 MAPK14 P2RY1 PLA2G4 PLA2G4A SRC	Bos taurus (cattle)
Interleukin-21 signaling	Cytokine receptor common subunit gamma Interleukin 21 receptor Interleukin Signal transducer and activator of transcription 5A Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A140T878 A0A3Q1ME65 E1BBE5 E1BEL4 F1MX38 F1MZV7 F1N0D6 F1N0R2 Q95115 Q95118	IL21 IL21R IL2RG JAK1 JAK3 MGF STAT1 STAT3 STAT4 STAT5A STAT5B	Bos taurus (cattle)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 10 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 11 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Aurora kinase A Aurora kinase Cell division cycle 16 Cell division cycle 20 Cell division cycle protein 23 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Fizzy/cell division cycle 20 related 1 (Drosophila) Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta RB transcriptional corepressor 1 SKP2 protein Serine/threonine-protein kinase PLK1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A3Q1M862 A0A3Q1MAR8 A0A452DI44 A0A452DIY4 A1A4R8 A7MB09 A7MBA2 A7Z061 E1B945 E1BAB6 E1BD83 E1BK11 E1BM34 E1BPM5 F1MBI1 F1MD46 F1MLV1 F1MRW5 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 F2Z4G9 G3N1P6 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q08DN4 Q17QP9 Q1RML1 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2TA06 Q2TA10 Q2TA25 Q2YDE4 Q32KL2 Q32L05 Q32PA5 Q3MHN0 Q3SX30 Q3SZ19 Q3SZ31 Q3SZC2 Q3SZT7 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCF6 Q3ZCK9 Q58DR0 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	AIK AIRK1 ANAPC1 ANAPC10 ANAPC11 ANAPC15 ANAPC16 ANAPC2 ANAPC4 ANAPC5 ANAPC7 ANAPC8 ARK1 AURA AURKA AURKB AYK1 BTAK CDC16 CDC20 CDC23 CDC26 CDC27 FZR1 IAK1 PLK1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RB1 RPS27A SKP2 STK15 STK6 SUG1 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 UBCH10 UBE2C UBE2D1 UBE2E1 UBE2S	Bos taurus (cattle)
Interferon alpha/beta signaling	ABCE1 protein Importin subunit alpha-5 Interferon 1AG1 Interferon 1AG8 Interferon alpha G Interferon alpha and beta receptor subunit 2 Interferon alpha/beta receptor 1 Interferon regulatory factor 9 Karyopherin subunit beta 1 Polyubiquitin-B Polyubiquitin-C Ribonuclease L Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A3Q1LPD3 A0A3Q1ME65 A0A3Q1MMI8 A2VE08 A4IFE6 A5H027 E1B7E8 E1B8Z4 E1BDZ1 E1BFV0 F1MCX4 F1MSN0 F1MXT2 F1N0D6 F1N6A7 G3MYH9 P0CG53 P0CH28 P62992 P63048 Q04790 Q58DC4 Q9BEG9	ABCE1 IF1AG1 IF1AG8 IFNAC IFNAR IFNAR1 IFNAR2 IRF9 ISGF3G JAK1 KPNA1 KPNB1 LOC100335490 LOC523244 LOC618947 LOC783912 RNASEL RPS27A SOCS1 SOCS3 STAT1 STAT2 TYK2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2	Bos taurus (cattle)
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor	A0A452DI80 F1MCK3 F1N5C5 P41985	CHRM1 CHRM2 CHRM3 CHRM5	Bos taurus (cattle)
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 5-hydroxytryptamine receptor 2A 5-hydroxytryptamine receptor 2B Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Amyloid-beta A4 protein Angiotensinogen Annexin Appetite-regulating hormone Arginine vasopressin B1 bradykinin receptor Beta-adrenergic receptor kinase 1 Bombesin receptor subtype-3 C motif chemokine ligand 1 CYSLTR2 protein Chemokine interleukin-8-like domain-containing protein Chemokine interleukin-8-like domain-containing protein Cholecystokinin Coagulation factor II (Thrombin) receptor-like 2 Cysteinyl leukotriene receptor 1 Endothelin receptor type B Endothelin-1 receptor Endothelin-1 Endothelin-2 Endothelin-3 Extracellular calcium-sensing receptor F2R like thrombin or trypsin receptor 3 F2R like trypsin receptor 1 Free fatty acid receptor 2 Free fatty acid receptor 3 Free fatty acid receptor 4 G protein subunit beta 3 G protein subunit gamma 13 G protein-coupled receptor 132 G protein-coupled receptor 143 G protein-coupled receptor 17 G protein-coupled receptor 39 G protein-coupled receptor 65 G-protein coupled receptor 4 GNB4 protein Gastrin releasing peptide receptor Gastrin-releasing peptide Gastrin/cholecystokinin type B receptor Gastrin Glucagon receptor Glutamate metabotropic receptor 1 Glutamate metabotropic receptor 5 Gonadotropin releasing hormone 2 Gonadotropin-releasing hormone receptor Growth hormone secretagogue receptor type 1 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein subunit alpha-11 Guanine nucleotide-binding protein subunit alpha-14 Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma KISS1 receptor KiSS-1 metastasis suppressor Kininogen 1 LPAR4 protein Leukotriene B4 receptor 1 Leukotriene B4 receptor 2 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 3 Lysophosphatidic acid receptor 5 Lysophosphatidic acid receptor 6 Melanin concentrating hormone receptor 2 Melanin-concentrating hormone receptor 1 Melanopsin Motilin receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Neuromedin B receptor Neuromedin S Neuromedin U receptor 1 Neuromedin U receptor 2 Neuromedin-K receptor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Neuropeptide S receptor 1 Neuropeptide S Neurotensin receptor 1 Neurotensin receptor 2 Neurotensin/neuromedin N Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Ovarian cancer G-protein coupled receptor 1 Oxytocin receptor Oxytocin-neurophysin 1 P2Y purinoceptor 1 P2Y purinoceptor 2 P2Y receptor family member 10 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Platelet-activating factor receptor Pro-FMRFamide-related neuropeptide FF Pro-MCH Pro-glucagon Pro-thyrotropin-releasing hormone Progonadoliberin Prokineticin 1 Prokineticin 2 Prokineticin receptor 2 Promotilin Prostaglandin E receptor 1 Prostaglandin F2-alpha receptor Protachykinin-1 Proteinase-activated receptor 1 Prothrombin Purinergic receptor P2Y11 Pyrimidinergic receptor P2Y6 Pyroglutamylated RFamide peptide receptor Pyroglutamylated RFamide peptide RGS17 protein Regulator of G protein signaling 13 Regulator of G protein signaling 18 Regulator of G protein signaling 21 Regulator of G protein signaling like 1 Regulator of G-protein signaling 16 Regulator of G-protein signaling 19 Regulator of G-protein signaling 1 Regulator of G-protein signaling 2 Regulator of G-protein signaling 4 Regulator of G-protein signaling 5 Rho guanine nucleotide exchange factor 25 Substance-K receptor Substance-P receptor Tachykinin-3 Thromboxane A2 receptor Thyrotropin-releasing hormone receptor Type-1 angiotensin II receptor Tyrosine-protein kinase Uncharacterized protein Urotensin 2B Urotensin-2 Vasopressin V1a receptor Vasopressin V1b receptor X-C motif chemokine receptor 1 non-specific serine/threonine protein kinase	A0A140T858 A0A140T8B9 A0A140T8C8 A0A3Q1LTV3 A0A3Q1LUG2 A0A3Q1LXY0 A0A3Q1LYG0 A0A3Q1M7J7 A0A3Q1M9C6 A0A3Q1MAT2 A0A3Q1MSN3 A0A3Q1MXN7 A0A3Q1MXY0 A0A3Q1N2W6 A0A3Q1N6F4 A0A3Q1NGS8 A0A3S5ZPL0 A0A452DI66 A0A452DI80 A0A452DII4 A0A452DIJ2 A0A452DKE4 A1Z2Z3 A2VEA2 A4IFB7 A4IFL6 A4IFV1 A5PKD6 A5PKG3 A6QL49 A6QLQ7 A6QM11 A7MB13 A7MBG6 A7MBH4 B5U8Y5 B9VJV9 B9VJW0 C3W8S1 E1B7W0 E1B8Q3 E1BA29 E1BC83 E1BCZ7 E1BEK2 E1BFS5 E1BH23 E1BH62 E1BHL6 E1BJI3 E1BKB6 E1BKC0 E1BL07 E1BLD8 E1BMB5 E1BMI3 E1BMN4 F1MCC4 F1MCK3 F1MDE0 F1MDI7 F1MDQ5 F1ME85 F1MG23 F1MGA6 F1MIX5 F1MJD1 F1MJZ0 F1MLS2 F1MMX1 F1MN36 F1MPG4 F1MPN9 F1MRY8 F1MSD7 F1MTB2 F1MU50 F1MUR0 F1MUY4 F1MWG2 F1MX11 F1MXG2 F1MXG7 F1MY53 F1MYW8 F1N1Y7 F1N2D2 F1N2V3 F1N2X0 F1N3V3 F1N4J9 F1N4Y7 F1N5C5 F1N650 F1N7R3 F6PV87 F6QI78 G3MWJ9 G3N1H2 G3X6J0 G3X6Q0 G5E581 O46471 O46639 O46685 P01017 P01156 P01175 P01272 P01289 P01352 P02698 P05363 P08858 P10894 P11017 P17322 P21146 P21450 P23726 P23727 P25104 P28088 P30671 P32236 P32871 P35384 P38408 P38409 P41520 P48042 P50154 P56449 P62871 P63212 P63214 P63217 Q08DC7 Q0GBZ5 Q0VBW7 Q1JQB3 Q28024 Q29RM9 Q3SZ98 Q3T0T8 Q3T181 Q3ZC80 Q3ZC95 Q5E9F0 Q863C3 Q867A9 Q8SPN1 Q95125 Q9BDJ2 Q9BDJ6 Q9TTY5 Q9TUX7	ADRA1A ADRA1B ADRA1D ADRBK1 AGT AGTR1 ANXA1 APP ARHGEF25 AVP AVPR1A AVPR1B BDKRB2 BRS3 BTK CASR CCK CCKBR CHRM1 CHRM3 CHRM5 CYSLTR1 CYSLTR2 EDN1 EDN2 EDN3 EDNRA EDNRB F2 F2R F2RL1 F2RL2 F2RL3 FFAR2 FFAR3 FFAR4 GAS GAST GCG GCGR GHRL GHSR GNA11 GNA14 GNA15 GNAQ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT12 GNGT2 GNGT3 GNGT5 GNGT7 GNGT8 GNRH1 GNRH2 GNRHR GPR120 GPR132 GPR143 GPR17 GPR39 GPR4 GPR41 GPR43 GPR65 GPR68 GPR73L1 GPR92 GPRC2A GRK2 GRM1 GRM5 GRP GRPR HCRTR1 HCRTR2 HTR2A HTR2B KISS1 KISS1R KNG1 LOC112445811 LOC508666 LPAR1 LPAR2 LPAR3 LPAR4 LPAR5 LPAR6 LTB4R LTB4R2 MCHR1 MCHR2 MLN MLNR NKA NKNA NKNB NMBR NMS NMUR1 NMUR2 NPFF NPFFR1 NPFFR2 NPS NPSR1 NTS NTSR1 NTSR2 OPN4 OXT OXTR P2RY1 P2RY10 P2RY11 P2RY2 P2RY5 P2RY6 PAFR PCAR1 PIK3CA PIK3R1 PIK3R2 PIK3R3 PKR2 PLCB1 PLCB4 PMCH PROK1 PROK2 PROKR2 PTAFR PTGER1 PTGFR QRFP QRFPR RGS1 RGS13 RGS16 RGS17 RGS18 RGS19 RGS2 RGS21 RGS3 RGS4 RGS5 RGSL1 SERPINA8 TAC1 TAC2 TAC2R TAC3 TACR1 TACR2 TACR3 TBXA2R TRH TRHR TRIO UTS2 UTS2B XCL1 XCL2 XCR1 mln	Bos taurus (cattle)

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