GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **557** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
RUNX1 regulates transcription of genes involved in differentiation of HSCs	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 CDK-activating kinase assembly factor MAT1 Core-binding factor subunit beta Cyclin-H Cyclin-dependent kinase 7 E3 ubiquitin-protein ligase GATA binding protein 1 GATA binding protein 3 Histone-lysine N-methyltransferase LIM domain binding 1 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit alpha type Proteasome subunit beta type-10 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-8 Proteasome subunit beta type-9 Proteasome subunit beta Proteasome subunit beta Rhombotin-1 Rhombotin-2 Runt-related transcription factor TAL bHLH transcription factor 1, erythroid differentiation factor Transcription factor 12 Transcription factor E2-alpha Tumor protein p73 Tyrosine-protein kinase Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Yes1 associated transcriptional regulator	A0A3Q1LI98 A0A3Q1LQN2 A0A3Q1M323 A0A3Q1MGB0 A0A3Q1ML13 A0A452DI44 A0A452DI60 A0A452DIY4 A7MBA2 E1B9S8 E1BAD4 E1BAU0 E1BD83 E1BI59 F1MBI1 F1MGQ5 F1MHA1 F1MK73 F1MLV1 F1MV33 F1MWE0 F1MXE4 F1MYH8 F1N6Z0 G3X6J7 G5E589 P0CG53 P0CH28 P33672 P56701 P62194 P62992 P63048 Q08DX5 Q0P5B3 Q17QP9 Q2KI42 Q2KJ25 Q2KJ46 Q2KJE7 Q2YDE4 Q32KL2 Q3MHN0 Q3SX30 Q3SX39 Q3SZ19 Q3SZC2 Q3T030 Q3T0T1 Q3T0X5 Q3T0Y5 Q3T108 Q3T112 Q3ZBD0 Q3ZBG0 Q3ZCK9 Q58DU5 Q5E964 Q5E987 Q5E9F9 Q5E9G3 Q5E9K0	ABL1 CBFB CCNH CDK7 GATA1 GATA3 ITCH KMT2A LDB1 LMO1 LMO2 MNAT1 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB4 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC2 PSMC3 PSMC4 PSMC5 PSMC6 PSMD1 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD5 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RBTN1 RPS27A RUNX1 SUG1 TAL1 TCF12 TCF3 TP73 TRAP2 UBA52 UBA80 UBB UBC UBCEP1 UBCEP2 YAP1	Bos taurus (cattle)
RUNX1 regulates estrogen receptor mediated transcription	Core-binding factor subunit beta Estrogen receptor Runt-related transcription factor	E1B9S8 E1BAD4 P49884	CBFB ESR ESR1 NR3A1 RUNX1	Bos taurus (cattle)
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known	ACTL6A protein AT-rich interaction domain 1A AT-rich interaction domain 1B Actin-like protein 6B Activator of transcription and developmental regulator AUTS2 CBX6 protein Casein kinase II subunit alpha Casein kinase II subunit alpha Casein kinase II subunit beta Chromobox 2 Chromobox 4 Chromobox 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase RING2 Homeodomain interacting protein kinase 2 Polybromo 1 Polycomb complex protein BMI-1 Polycomb group RING finger protein 5 Polyhomeotic homolog 1 Polyhomeotic homolog 2 Polyhomeotic homolog 3 RING1 and YY1 binding protein Runt-related transcription factor SMARCA2 protein SMARCE1 protein SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 Scm polycomb group protein homolog 1 Transcription activator BRG1 YY1 associated factor 2 histone acetyltransferase	A0A3Q1LF83 A0A3Q1LHD2 A0A3Q1M2B9 A0A3Q1MBA7 A0A3Q1MCA3 A0A3Q1MDR6 A0A3Q1MHM3 A0A3Q1MXM3 A0JN86 A3KMW6 A4FUX8 A4IFJ8 A5PKF6 A5PKK5 A6QLQ0 A7Z019 E1B8D6 E1B9S8 E1BAD4 E1BBV6 E1BFG7 E1BHH0 E1BJD1 E1BPK9 F1MJ55 F1MKU2 F1MTG9 F1MYU1 P67868 P68399 Q0II51 Q0VC56 Q32KX7 Q5BIN2	ACTL6 ACTL6A ACTL6B ARID1A ARID1B AUTS2 BAF190A BAF47 BAF53B BMI1 BRG1 CBFB CBX2 CBX4 CBX6 CBX8 CK2A1 CK2N CSNK2A1 CSNK2A2 CSNK2B EP300 HIPK2 PBRM1 PCGF4 PCGF5 PHC1 PHC2 PHC3 RNF2 RUNX1 RYBP SCMH1 SMARCA2 SMARCA4 SMARCB1 SMARCC1 SMARCD1 SMARCD2 SMARCD3 SMARCE1 SNF2B SNF2L4 YAF2	Bos taurus (cattle)
ROS and RNS production in phagocytes	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Natural resistance-associated macrophage protein 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Nitric oxide synthase Nitric oxide synthase Nitric oxide synthase Ras-related C3 botulinum toxin substrate 2 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B, brain isoform V-type proton ATPase subunit B, kidney isoform V-type proton ATPase subunit C 1 V-type proton ATPase subunit C V-type proton ATPase subunit E 1 V-type proton ATPase subunit E 2 V-type proton ATPase subunit F V-type proton ATPase subunit G 1 V-type proton ATPase subunit G 2 V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit a V-type proton ATPase subunit d 1 V-type proton ATPase subunit d 2 V-type proton ATPase subunit e 1 V-type proton ATPase subunit Voltage-gated hydrogen channel 1	A0A3Q1LSD1 A0A3Q1M6M2 A0A3Q1MKI4 A0A3Q1MS24 A0A3Q1MTW8 A0A3Q1NF89 A0A452DHY1 A0A452DI38 A0A452DJ67 A4IFJ9 E1BGJ7 E1BMV6 F1MJ63 F1MYR5 O46521 O46522 O46563 O97681 P11019 P21282 P31404 P31407 P31408 P61420 P79251 P81103 Q0VCV6 Q1RMS1 Q28029 Q2KJB6 Q2TA24 Q32LB7 Q9TU25	ATP6A1 ATP6B1 ATP6B2 ATP6C ATP6D ATP6E ATP6G ATP6G1 ATP6H ATP6N1B ATP6S14 ATP6V0A1 ATP6V0A2 ATP6V0A4 ATP6V0B ATP6V0C ATP6V0D1 ATP6V0D2 ATP6V0E ATP6V0E1 ATP6V0E2 ATP6V1A ATP6V1A1 ATP6V1B1 ATP6V1B2 ATP6V1C1 ATP6V1C2 ATP6V1E1 ATP6V1E2 ATP6V1F ATP6V1G1 ATP6V1G2 ATP6V1G3 ATP6V1H CYBA CYBB HVCN1 LOC101904667 NCF1 NCF2 NCF4 NOS1 NOS2 NOS3 RAC2 SLC11A1 TCIRG1 VATC VATF VPATPD	Bos taurus (cattle)
RND1 GTPase cycle	Aldehyde dehydrogenase family 3 member A2 Ankyrin repeat domain containing 26 Carboxypeptidase D Caveolin-1 Coiled-coil domain containing 88A DEP domain containing 1B Desmoplakin Discs large MAGUK scaffold protein 5 Dystonin Epithelial stromal interaction 1 FRS3 protein Family with sequence similarity 135 member A Family with sequence similarity 83 member B Fibroblast growth factor receptor substrate 2 Flotillin-2 Growth factor receptor-bound protein 7 Kinase D interacting substrate 220 Kinesin family member 14 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plakophilin 4 Pleckstrin homology and RhoGEF domain containing G5 Plexin A1 Protein tyrosine phosphatase non-receptor type 13 RAS protein activator like 2 RNA binding motif protein 39 RNA binding motif protein X-linked Rho GTPase activating protein 5 Rho GTPase-activating protein 35 Rho-related GTP-binding protein Rho6 Stathmin Stress-induced-phosphoprotein 1 Thioredoxin like 1 Transferrin receptor protein 1 Transmembrane protein 59 UBX domain protein 11 Vang-like protein Vang-like protein receptor protein-tyrosine kinase tRNA (34-2'-O)-methyltransferase regulator WDR6	A0A3Q1LJ52 A0A3Q1LNS9 A0A3Q1LRJ9 A0A3Q1LTK4 A0A3Q1LWZ4 A0A3Q1M6F8 A0A3Q1M8V3 A0A3Q1ME81 A0A3Q1MNK3 A0A452DIX7 A6H792 A6QLR4 D3JUI8 E1B7I9 E1B801 E1BFR4 E1BIG6 E1BJ31 E1BKT4 E1BKT9 E1BLB3 E1BLC3 E1BLR9 E1BM23 E1BMF4 E1BNR7 F1MFE8 F1MI76 F1MJ11 F1MPJ6 F1MPT5 F1N5P7 G5E5S3 P23726 P23727 P79132 Q1RMW5 Q2HJ68 Q3T0Q2 Q3ZBZ8	ALDH3A2 ANKRD26 ARHGAP35 ARHGAP5 CAV1 CCDC88A CPD DEPDC1B DLG5 DSP DST EPHA2 EPSTI1 FAM135A FAM83B FLOT2 FRS2 FRS3 GRB7 KIDINS220 KIF14 PIK3R1 PIK3R2 PKP4 PLEKHG5 PLXNA1 PTPN13 RASAL2 RBM39 RBMX RHO6 RND1 STIP1 STMN2 TFRC TMEM59 TXNL1 UBXN11 VANGL1 VANGL2 WDR6	Bos taurus (cattle)
RIP-mediated NFkB activation via ZBP1	ATP-dependent RNA helicase A Inhibitor of nuclear factor kappa-B kinase subunit alpha Inhibitor of nuclear factor kappa-B kinase subunit beta Myeloid differentiation primary response protein MyD88 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha (Fragment) NF-kappa-B inhibitor-interacting Ras-like protein 2 NF-kappaB transcription factor p65 subunit NFKB inhibitor interacting Ras like 1 NFKB2 protein Nuclear factor NF-kappa-B p105 subunit Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	A0A3Q1LZM4 A0A452DHW6 A1XG22 A7MBB7 F1MKW9 Q0IIB2 Q1JPF1 Q28141 Q8WNW7 Q95KU9 Q95KV0 Q95KV1	CHUK DDX9 DHX9 IKBKB IKBKG IKKA MYD88 NDH2 NEMO NFKB1 NFKB2 NFKBIA NFKBIB NKIRAS1 NKIRAS2 RELA bIkBa	Bos taurus (cattle)
RHOQ GTPase cycle	ADP ribosylation factor like GTPase 13B Actin nucleation-promoting factor WASL Anion exchange protein CDC42 effector protein (Rho GTPase binding) 3 CDC42 effector protein (Rho GTPase binding) 4 CPNE8 protein Caveolin-1 Cdc42 effector protein 1 Cdc42 effector protein 2 Cell division control protein 42 homolog Cystic fibrosis transmembrane conductance regulator DEP domain containing 1B Diaphanous related formin 3 E3 ubiquitin-protein ligase Formin binding protein 1 GIT ArfGAP 1 GIT ArfGAP 2 Gap junction alpha-1 protein Golgi associated PDZ and coiled-coil motif containing IQ motif containing GTPase activating protein 1 IQGAP3 protein Intersectin 1 Junction plakoglobin MAGUK p55 subfamily member 7 Neutral amino acid transporter B(0) Oligophrenin-1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Pleckstrin homology and RhoGEF domain containing G3 Ragulator complex protein LAMTOR1 Ras homolog family member Q Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 SLIT-ROBO Rho GTPase activating protein 2 STEAP3 metalloreductase STOM protein Scribble planar cell polarity protein Serine/threonine-protein kinase PAK 1 Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Thyroid hormone receptor interactor 10 Transferrin receptor protein 1 Vang-like protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4	A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LPM3 A0A3Q1LPT9 A0A3Q1LUY1 A0A3Q1LWV5 A0A3Q1LX25 A0A3Q1M0G8 A0A3Q1M7Q3 A0A3Q1MA22 A0A3Q1MPX4 A0A3Q1MXC6 A0A3Q1N6J8 A2VDU0 A5D784 A6H7H0 A6QQZ7 A8E4P3 E1B801 E1BAX1 E1BI41 E1BIG6 E1BKY4 E1BLB3 E1BM23 E1BMN2 E1BNR7 E1BP72 F1MBM9 F1MC48 F1MIZ6 F1MK42 F1MN01 F1MNI8 F1MS60 F1MXU4 F1N1Q7 F1N7Q8 F6RWK1 G3MWI1 P18246 P79132 Q08DN6 Q08E52 Q17QW1 Q17QZ0 Q2KI46 Q2KJ93 Q2T9M8 Q3T0D8 Q8SPJ1 Q95107 Q95JC7	ARHGAP1 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP5 ARHGEF7 ARHGEF9 ARL13B ASCT2 BORG1 BORG5 CAV1 CDC42 CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CEP2 CFTR CPNE8 DEPDC1B DIAPH3 DLC1 FNBP1 GIT1 GIT2 GJA1 GOPC IQGAP1 IQGAP3 ITSN1 JUP LAMTOR1 MPP7 OPHN1 PAK1 PAK2 PAK4 PLEKHG3 PREX1 RHOQ SCRIB SLC1A5 SLC4A7 SNAP23 SRGAP2 STEAP3 STOM SYDE1 TFRC TRIP10 VANGL1 WASL WWP2	Bos taurus (cattle)
RHOH GTPase cycle	Anion exchange protein BRWD2 protein Caveolin-1 Endoplasmic reticulum protein 27 Family with sequence similarity 91 member A1 Glioblastoma amplified sequence Junction plakoglobin Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial Methionine synthase NSFL1 cofactor p47 Neutral amino acid transporter B(0) Oxysterol-binding protein P21 (RAC1) activated kinase 6 Ragulator complex protein LAMTOR1 Ral GTPase activating protein catalytic subunit alpha 1 Ras homolog family member H Rho GDP-dissociation inhibitor 1 Rho GDP-dissociation inhibitor 3 Rho-associated protein kinase STOM protein Serine/threonine-protein kinase PAK 1 Transferrin receptor protein 1 Transitional endoplasmic reticulum ATPase Transmembrane protein 59 Tyrosine-protein kinase CSK Tyrosine-protein kinase Tyrosine-protein kinase Vang-like protein non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4	A0A3Q1LSV4 A0A3Q1M0G8 A0A3Q1M346 A0A3Q1MW77 A0A452DIS6 A0A452DJ82 A6QLS8 A8E4P3 E1BA03 E1BIG6 E1BJC1 E1BMP9 E1BNR7 F1MF50 F1MQF4 F1MY55 F1N7X6 G3MWI1 G3X757 P11181 P79132 Q08E52 Q0II80 Q0VBZ0 Q17QZ0 Q3SWX4 Q3SZC4 Q3T0D8 Q3T0Q2 Q3ZCM0 Q8SPJ1 Q95JC7	ARHGDIA ARHGDIG ASCT2 BRWD2 CAV1 CSK DBT ERP27 FAM91A1 GBAS JUP LAMTOR1 LCK MTR NIPSNAP2 NSFL1C OSBPL11 PAK1 PAK2 PAK4 PAK5 PAK6 RALGAPA1 RHOH ROCK1 ROCK2 SLC1A5 SLC4A7 STOM TFRC TMEM59 VANGL1 VCP WDR11 ZAP70	Bos taurus (cattle)
RHOF GTPase cycle	A-kinase anchoring protein 12 Actin, cytoplasmic 1 Actin, cytoplasmic 2 Adducin 3 Alpha-actinin-1 Anion exchange protein BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain containing adaptor protein 2 like 2 Brain acid soluble protein 1 Caveolin-1 DEP domain containing 1B Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 169 member A Family with sequence similarity 62 (C2 domain containing), member A Lamin B1 Melanoma cell adhesion molecule Myosin IXB Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Rho GTPase activating protein 12 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho-related GTP-binding protein RhoF SLIT-ROBO Rho GTPase activating protein 2 STEAP3 metalloreductase SUMO specific peptidase 1 Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein Torsin-1A-interacting protein 1 Vang-like protein	A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LUD9 A0A3Q1M6Y9 A0A3Q1MFX1 A0A3Q1MRR8 A0A3Q1MSB2 A0A3Q1NDE1 A0A452DIN5 A0JN43 E1BFE6 E1BHQ9 E1BLB3 E1BM23 E1BMN2 E1BNR7 E1BNV7 F1MFC6 F1MXR0 F1MXU4 F1N4E5 F1N5F9 F1N7Q8 F6RWK1 G3MWI1 P23726 P23727 P60712 P63258 P79132 P80724 Q2T9M8 Q3B7N2 Q3SZA1	ACTB ACTG ACTG1 ACTN1 ADD3 AKAP12 ARHGAP1 ARHGAP12 ARHGAP32 ARHGAP39 ARHGAP5 BAIAP2L1 BAIAP2L2 BASP1 CAV1 DEPDC1B DIAPH1 DIAPH2 DIAPH3 ESYT1 FAM169A FAM62A FARP1 LMNB1 MCAM MTMR1 MYO9B NAP22 PIK3R1 PIK3R2 RHOF SENP1 SLC4A7 SNAP23 SRGAP2 STEAP3 SYDE1 TOR1AIP1 VANGL1	Bos taurus (cattle)
RHOD GTPase cycle	A-kinase anchoring protein 12 Adducin 3 Adenosine 5'-monophosphoramidase HINT2 Alpha-actinin-1 Anion exchange protein Ankyrin repeat and FYVE domain containing 1 CPNE8 protein Caveolin-1 DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 2 Diaphanous related formin 3 EF-hand domain-containing protein D2 EMD protein Family with sequence similarity 62 (C2 domain containing), member A Filamin A interacting protein 1 Golgin A2 Lamin B1 Lectin, mannose binding 1 Melanoma cell adhesion molecule Motile sperm domain containing 2 P21 (RAC1) activated kinase 6 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Plexin A1 Plexin B1 Progesterone receptor membrane component 2 RNA binding motif protein 39 Rac GTPase activating protein 1 Ras homolog family member D Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 STEAP3 metalloreductase Starch binding domain 1 Torsin-1A-interacting protein 1 Vang-like protein Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A3Q1LLI7 A0A3Q1LNB6 A0A3Q1LNG7 A0A3Q1LPT9 A0A3Q1LTM9 A0A3Q1LUD9 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1M0A2 A0A3Q1M6Y9 A0A3Q1MD15 A0A3Q1MRR8 A0A3Q1MSA1 A0A3Q1MSB2 A0A3Q1MZP2 A0A3Q1N078 A0A3Q1NDE1 A0JN43 A2VDZ9 A5D784 A5D7A0 A6QQV8 E1B7F6 E1B801 E1BA03 E1BAJ4 E1BFR4 E1BHQ9 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNR7 F1MY55 F1N4E5 F1N7C7 F1N7Q8 F6QJJ8 F6RWK1 G3MWI1 P23726 P23727 P79132 Q3B7N2 Q3SX08 Q8SQ21	ACTN1 ADD3 AKAP12 ANKFY1 ARHGAP1 ARHGAP12 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 CAV1 CPNE8 DEPDC1B DIAPH1 DIAPH2 DIAPH3 EFHD2 EMD ESYT1 FAM62A FILIP1 GOLGA2 HINT2 LBR LMAN1 LMNB1 MCAM MOSPD2 PAK5 PAK6 PGRMC2 PIK3R1 PIK3R2 PLXNA1 PLXNB1 RACGAP1 RBM39 RHOD SLC4A7 STBD1 STEAP3 SWS1 TOR1AIP1 VANGL1 VAPB VRK2	Bos taurus (cattle)
RHOC GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Anillin, actin binding protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain containing 187 Complement component 1 Q subcomponent-binding protein, mitochondrial DEP domain containing 1B Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Flotillin-1 Flotillin-2 Formin like 3 Formin-like protein 2 IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Rac GTPase activating protein 1 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 5 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 5 Rho-associated protein kinase Rho-related GTP-binding protein RhoC Rhotekin STOM protein Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 Syntaxin-5 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LSX9 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LWV5 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1MEH9 A0A3Q1MN47 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MW77 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DJ82 A1A4I4 A2VDZ9 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7Z038 A8E4P3 E1B718 E1B801 E1BH05 E1BHQ9 E1BIG6 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 F1MBT6 F1MC48 F1MCN4 F1MDL7 F1MEK6 F1MF50 F1MFK1 F1MIZ6 F1MJH8 F1MS34 F1N1Q7 F1N2G5 F1N7Q8 F6RWK1 G3X696 P23727 P61585 P79132 Q08DB5 Q08DN8 Q1RMJ6 Q3T0B6 Q8SPJ1	ABCD3 ABR ACBD5 AKAP13 ANLN ARHA ARHC ARHGAP1 ARHGAP18 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP5 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF17 ARHGEF25 ARHGEF28 ARHGEF5 BCR C1QBP CAV1 CAVIN1 DAAM1 DEPDC1B DIAPH1 DIAPH3 DLC1 FLOT1 FLOT2 FMNL2 FMNL3 IQGAP1 IQGAP3 JUP LBR LMAN1 LOC787891 MCAM MCF2L MYO9B OPHN1 PIK3R1 PKN PKN1 PKN2 PKN3 PREX1 PRK1 PRKCL1 RACGAP1 RHO12 RHOA RHOC ROCK1 ROCK2 RTKN SLK STARD13 STOM STX5 TFRC TJP2 VANGL1 VAPB VAV2	Bos taurus (cattle)
RHOBTB2 GTPase cycle	Actin, cytoplasmic 2 Alpha-actinin-1 Cullin 3 Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Heterogeneous nuclear ribonucleoprotein C (C1/C2) Hsp90 co-chaperone Cdc37 Pleckstrin homology domain interacting protein RNA binding motif protein X-linked Rho-related BTB domain containing 2 Serine and arginine repetitive matrix 1 Serine/threonine-protein kinase 38 Spliceosome RNA helicase DDX39B T-complex protein 1 subunit beta T-complex protein 1 subunit eta T-complex protein 1 subunit zeta Thioredoxin like 1 Transformer-2 protein homolog beta Tropomodulin 3 Twinfilin-1 Unconventional myosin-VI	A0A3Q1LL62 A0A3Q1ME81 A0A3Q1MP80 A0A3Q1NES9 A0A498UZ20 A2VDV2 D3JUI8 E1BIN5 F1MPF7 F1MZJ4 P63258 Q2NKZ1 Q3B7N2 Q3MHL7 Q3SX47 Q3T147 Q3ZBH0 Q3ZBT6 Q5EAC6 Q76LV1 Q76LV2	ACTG ACTG1 ACTN1 BAT1 CCT2 CCT6A CCT7 CDC37 CUL3 DDX39B HNRPC HSP90A HSP90AA1 HSP90AB1 HSPC3 HSPCA HSPCB MYO6 PHIP RBMX RHOBTB2 SFRS10 SRRM1 STK38 TMOD3 TRA2B TWF1 TXNL1 UAP56	Bos taurus (cattle)
RHOBTB1 GTPase cycle	COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 4 Cleavage and polyadenylation specific factor 7 Cullin 3 E3 ubiquitin-protein ligase BRE1A G protein pathway suppressor 1 Heterogeneous nuclear ribonucleoprotein C (C1/C2) RB binding protein 6, ubiquitin ligase RNA binding motif protein X-linked Rho related BTB domain containing 1 Rho-associated protein kinase Serine and arginine repetitive matrix 1 Serine/threonine-protein kinase 38 T-complex protein 1 subunit beta T-complex protein 1 subunit eta Thioredoxin like 1 Transformer-2 protein homolog beta Unconventional myosin-VI Vimentin cGMP-specific 3',5'-cyclic phosphodiesterase non-specific serine/threonine protein kinase	A0A3Q1ME43 A0A3Q1ME81 A0A3Q1MP80 A0A3Q1MW77 A0A498UZ20 A2VDP1 A2VDV2 D3JUI8 E1BCZ2 E1BIN5 F1MF50 F1MIH7 F1MU62 G3X736 P48616 Q28156 Q2NKZ1 Q3SX47 Q3SZA0 Q3ZBH0 Q3ZBT6	BRE1A CCT2 CCT7 COPS2 COPS4 CPSF7 CUL3 GPS1 HNRPC LOC782101 MYO6 PDE5 PDE5A RBBP6 RBMX RHOBTB1 RNF20 ROCK1 ROCK2 SFRS10 SRRM1 STK38 TRA2B TXNL1 VIM	Bos taurus (cattle)
RHOA GTPase cycle	A-kinase anchoring protein 13 ABCD3 protein Actin, alpha cardiac muscle 1 Active breakpoint cluster region-related protein Acyl-CoA-binding domain-containing protein 5 Aladin WD repeat nucleoporin Anillin, actin binding protein ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 B-cell receptor-associated protein BCR activator of RhoGEF and GTPase Caveolae associated protein 1 Caveolin-1 Coiled-coil domain-containing protein 115 Complement component 1 Q subcomponent-binding protein, mitochondrial DDRGK domain-containing protein 1 DEP domain containing 1B Dedicator of cytokinesis 2 Delta(14)-sterol reductase LBR Diaphanous related formin 1 Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 ER membrane protein complex subunit 3 Endoplasmic reticulum protein 27 FAS-associated factor 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 Family with sequence similarity 13 member A Flotillin-1 Flotillin-2 Formin like 3 GMIP protein IQ motif containing GTPase activating protein 1 IQGAP3 protein Junction plakoglobin Kinectin 1 Lectin, mannose binding 1 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB Neuroepithelial cell transforming 1 Neuronal guanine nucleotide exchange factor Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G5 Pleckstrin homology and RhoGEF domain containing G6 Progesterone receptor membrane component 2 Proto-oncogene vav Protocadherin 7 Rac GTPase activating protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 18 Rho GTPase activating protein 19 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 28 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase activating protein 8 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 like Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 17 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 1 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 28 Rho guanine nucleotide exchange factor 2 Rho guanine nucleotide exchange factor 3 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho-GAP domain-containing protein Rho-associated protein kinase Rho/Rac guanine nucleotide exchange factor 18 Rhophilin-2 Rhotekin SLIT-ROBO Rho GTPase activating protein 1 STOM protein Sec1 family domain containing 1 Serine/threonine-protein kinase N1 StAR related lipid transfer domain containing 13 StAR related lipid transfer domain containing 8 Starch binding domain 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Syntaxin-5 T-cell activation GTPase activating protein TMEM87A protein Testis expressed 2 Tight junction protein 2 Transferrin receptor protein 1 Transforming protein RhoA V-type proton ATPase subunit S1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B heme oxygenase (biliverdin-producing) non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase protein kinase C protein kinase C	A0A3Q1LFQ5 A0A3Q1LGT5 A0A3Q1LHF1 A0A3Q1LKT3 A0A3Q1LM61 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LQ45 A0A3Q1LUD9 A0A3Q1LUW4 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LX25 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M851 A0A3Q1M8D9 A0A3Q1MA88 A0A3Q1MAP3 A0A3Q1MD11 A0A3Q1MEH9 A0A3Q1MFP5 A0A3Q1MN47 A0A3Q1MPX1 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MW77 A0A3Q1N5A2 A0A3Q1N6F4 A0A3Q1N6J8 A0A452DIS6 A0A452DJ82 A1A4I4 A2VDZ9 A4FUC9 A4FV18 A4FV22 A6H7H0 A6QLR4 A6QNS3 A6QQV8 A7YY57 A7Z038 A8E4P3 E1B718 E1B801 E1B9G8 E1BAJ4 E1BBA0 E1BBD2 E1BCC1 E1BCK4 E1BDL7 E1BDY4 E1BG76 E1BH05 E1BH51 E1BHQ9 E1BI70 E1BIG6 E1BIM3 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BNE7 E1BNR7 E1BNV7 E1BP14 E1BQ24 F1MBM9 F1MBT6 F1MC48 F1MCL8 F1MCN4 F1MEK6 F1MF50 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MGB9 F1MHI2 F1MIZ6 F1MJA6 F1MJH8 F1MK36 F1MLS2 F1MM72 F1MPJ6 F1MS34 F1MTN6 F1MTY9 F1MWY5 F1MYQ4 F1N1Q7 F1N2G5 F1N6V1 F1N7Q8 F6QCG0 F6QJJ8 F6RWK1 G3N2T3 G3X696 G5E6T2 P23726 P23727 P40682 P61585 P79132 Q08DA6 Q08DB1 Q08DB5 Q08DN7 Q08DN8 Q08DP6 Q2HJD0 Q2T9M8 Q3SZB5 Q3T000 Q3T0B6 Q3ZC07 Q3ZCB8 Q5E9F1 Q8SPJ1	AAAS ABCD3 ABR ACBD5 ACTC ACTC1 AKAP13 ANLN ARAP1 ARAP2 ARAP3 ARHA ARHGAP1 ARHGAP10 ARHGAP11A ARHGAP18 ARHGAP19 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP26 ARHGAP28 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP6 ARHGAP8 ARHGAP9 ARHGDIA ARHGEF1 ARHGEF10 ARHGEF10L ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF17 ARHGEF18 ARHGEF19 ARHGEF2 ARHGEF25 ARHGEF28 ARHGEF3 ARHGEF5 ARHGEF7 ATP6AP1 ATP6IP1 ATP6S1 BCAP31 BCR C1QBP CAV1 CAVIN1 CCDC115 DAAM1 DDRGK1 DEPDC1B DIAPH1 DIAPH3 DLC1 DOCK2 EMC3 ERP27 FAF2 FAM13A FARP1 FLOT1 FLOT2 FMNL3 GMIP HMOX2 IQGAP1 IQGAP3 JUP KTN1 LBR LMAN1 MCAM MCF2L MYO9B NET1 NGEF OPHN1 PCDH7 PGRMC2 PIK3R1 PIK3R2 PKN PKN1 PKN2 PKN3 PLD1 PLEKHG3 PLEKHG5 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RASGRF2 RHO12 RHOA RHPN2 ROCK1 ROCK2 RTKN SCFD1 SLK SNAP23 SRGAP1 STARD13 STARD8 STBD1 STOM STX5 TAGAP TEX2 TFRC TJP2 TMEM111 TMEM87A TRIO UBXD8 VANGL1 VAPB VAV1 VAV2 VAV3 YKT6	Bos taurus (cattle)
RHO GTPases activate IQGAPs	CAP-Gly domain containing linker protein 1 Cadherin-1 Calmodulin-like Catenin alpha 1 Catenin beta-1 Cell division control protein 42 homolog EF-hand domain-containing protein IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IQGAP3 protein Menin	A0A3Q1M9M0 A0A3Q1MQQ6 A0A3Q1MR28 A0A3Q1MSS6 A6H7H0 F1MC48 F1MLH6 F1MTR1 Q0P5I0 Q0VCX4 Q2KJ93	CALM CDC42 CDH1 CLIP1 CTNNA1 CTNNB1 IQGAP1 IQGAP2 IQGAP3 MEN1	Bos taurus (cattle)
RHO GTPases Activate NADPH Oxidases	Cytochrome b-245 heavy chain Cytochrome b-245 light chain Mitogen-activated protein kinase 11 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein S100-A8 Protein S100-A9 Protein kinase C beta type Protein kinase C delta type Protein kinase C Ras-related C3 botulinum toxin substrate 2 mitogen-activated protein kinase non-specific serine/threonine protein kinase	A0A3Q1LQK4 A0A3Q1LTT9 A0A3Q1MKI4 A0A3Q1MRR6 A0A3Q1MSP9 A0A3Q1MTW8 A0A452DHY1 A6QLW1 E1B8P9 E1BAA4 E1BFF3 E1BPJ7 F1MHS5 G3X793 O46521 O46522 P05126 P28782 P46196 Q5BIN5 Q9TU25	CYBA CYBB ERK2 MAPK1 MAPK11 MAPK14 MAPK3 NCF1 NCF2 NCF4 NOX1 NOX3 NOXO1 PIK3C3 PIK3R4 PIN1 PRKCB PRKCB1 PRKCD PRKCZ PRKM1 RAC2 S100A8 S100A9	Bos taurus (cattle)
RET signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Artemin DOK4 protein Docking protein 1 Docking protein 2 Docking protein 5 Docking protein 6 Fibroblast growth factor receptor substrate 2 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GRB2 associated binding protein 2 GRB2-associated-binding protein 1 Glial cell derived neurotrophic factor Growth factor receptor bound protein 10 Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 7 Insulin receptor substrate 2 Mitogen-activated protein kinase 7 Neurturin PDZ and LIM domain protein 7 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphoinositide-3-kinase regulatory subunit 3 Proto-oncogene tyrosine-protein kinase receptor Ret RAP1 GTPase activating protein SH3 and multiple ankyrin repeat domains 3 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A3Q1LNN8 A0A3Q1M0Y1 A0A3Q1M864 A0A3Q1MTG9 A0A3Q1N8H3 A0A452DJE2 A4IFA9 A4IFJ7 A5PKJ4 A6QLU3 A7MBB8 E1B7I9 E1BD76 E1BE66 E1BIM8 E1BKU1 F1MDQ5 F1MJE0 F1MP52 F1MRT5 F1MS00 F1MYF9 F1MYM3 F1N339 F1N7C3 F6S0Q2 G3MZM3 G3N3X9 G3X7B4 P00517 P23726 P23727 P32871 Q0IIE2 Q0VCR5 Q1RMW5 Q3SX40 Q3T0F9	ARTN DOK1 DOK2 DOK4 DOK5 DOK6 FRS2 GAB1 GAB2 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB10 GRB2 GRB7 IRS2 MAPK7 NRTN PDLIM7 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PRKACA PRKACB PTPN11 RAP1GAP RET SHANK3 SHC1 SHC3 SOS1 SRC	Bos taurus (cattle)
RAF/MAP kinase cascade	Alpha-actinin-2 Amphiregulin Angiopoietin-1 receptor Angiopoietin-1 Artemin Astrocytic phosphoprotein PEA-15 Betacellulin Calcium/calmodulin-dependent protein kinase type II subunit beta Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin-like Colony stimulating factor 2 receptor subunit beta Cytokine receptor common subunit gamma Discs large MAGUK scaffold protein 3 Discs large MAGUK scaffold protein 4 Disks large homolog 1 EF-hand domain-containing protein Epiregulin Epithelial mitogen FLT3LG protein FRS3 protein Fibroblast growth factor 1 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Focal adhesion kinase 1 GDNF family receptor alpha 4 GDNF family receptor alpha-1 GDNF family receptor alpha-2 GFRA3 protein GTPase NRas Glial cell derived neurotrophic factor Granulocyte-macrophage colony-stimulating factor Growth factor receptor-bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Insulin receptor substrate 1 Insulin receptor substrate 2 Interleukin 3 receptor subunit alpha Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 Interleukin-3 Interleukin-5 Kit ligand Klotho beta Klotho Linker for activation of T cells Mast/stem cell growth factor receptor Mitogen-activated protein kinase 1 Mitogen-activated protein kinase Neuregulin 2 Neuregulin 3 Neurofilament light polypeptide Neurturin Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Platelet-derived growth factor receptor alpha Platelet-derived growth factor receptor beta Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Pro-neuregulin-1, membrane-bound isoform Proheparin-binding EGF-like growth factor Proto-oncogene tyrosine-protein kinase receptor Ret RAS guanyl releasing protein 3 RAS guanyl releasing protein 4 RAS guanyl-releasing protein 1 Ral guanine nucleotide dissociation stimulator like 1 Ral guanine nucleotide dissociation stimulator like 3 Ral guanine nucleotide dissociation stimulator-like 2 Ral guanine nucleotide dissociation stimulator Ran-binding protein 9 Rap guanine nucleotide exchange factor 2 Ras protein specific guanine nucleotide releasing factor 1 Ras protein specific guanine nucleotide releasing factor 2 RasGEF domain family member 1A Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor protein-tyrosine kinase Receptor-type tyrosine-protein phosphatase alpha SHC adaptor protein 2 SHC adaptor protein 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Spectrin alpha, erythrocytic 1 Spectrin alpha, non-erythrocytic 1 Spectrin beta chain Spectrin beta chain Spectrin beta, non-erythrocytic 4 Transforming growth factor alpha Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase calcium/calmodulin-dependent protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase receptor protein-tyrosine kinase small monomeric GTPase	A0A3Q1LI10 A0A3Q1LK34 A0A3Q1LNC8 A0A3Q1LRU7 A0A3Q1LSU3 A0A3Q1LUE0 A0A3Q1M0Y1 A0A3Q1M3Q3 A0A3Q1M6Z6 A0A3Q1M7J4 A0A3Q1MBH0 A0A3Q1MD11 A0A3Q1ME99 A0A3Q1MFJ1 A0A3Q1MHB0 A0A3Q1MKB4 A0A3Q1MKC7 A0A3Q1MPB6 A0A3Q1MPT9 A0A3Q1MR28 A0A3Q1N010 A0A3Q1N3Z8 A0A3Q1N508 A0A3Q1N8H3 A0A3Q1NAC7 A0A3Q1NAV6 A0A452DHX3 A0A452DJB1 A0JNB0 A0MTF4 A2VE24 A2VE27 A2VE30 A4IFA9 A5D7R9 A6H792 A6QR62 B1H0W5 D8KXU9 E1B7I9 E1B8P9 E1BAI2 E1BBE2 E1BCP6 E1BD76 E1BDM2 E1BEL4 E1BFP8 E1BG59 E1BGY3 E1BHC1 E1BIN8 E1BJC7 E1BJU2 E1BKU1 E1BLT3 E1BM01 E1BMN5 E1BMX0 E1BP37 F1MCQ7 F1MEV4 F1MH16 F1MHC6 F1MJE0 F1MKE9 F1MLH6 F1MM66 F1MMQ8 F1MN51 F1MP52 F1MPD0 F1MRU0 F1MS00 F1MS28 F1MSG6 F1MXH7 F1MYE0 F1MYM3 F1MZ60 F1MZD6 F1N0D6 F1N4S9 F1N5N3 F1N6G8 F1N7C3 F2Z4J0 F6S0Q2 G3MXR4 G3MZM3 G3N104 G3XGD3 O18920 P02548 P03968 P03969 P05016 P11052 P23726 P23727 P32871 P46196 P49875 P52173 Q06807 Q0IIE2 Q0VCY4 Q0VCY8 Q28132 Q2HJF7 Q2KJ15 Q3MHJ9 Q3T0F9 Q3ZC55 Q95118 Z4YHD9	ACTN2 AFGF ANG1 ANGPT1 AREG ARTN BTC CALM CAMK2A CAMK2B CAMK2D CSF2 CSF2RB DLG1 DLG3 DLG4 EGFR EPGN ERBB2 ERBB3 ERBB4 EREG ERK2 FGF1 FGF10 FGF16 FGF17 FGF18 FGF19 FGF2 FGF20 FGF23 FGF3 FGF4 FGF4A FGF4C FGF5 FGF5B FGF5C FGF6 FGF6A FGF7 FGF7B FGF8 FGF8A FGF9 FGFA FGFR1 FGFR2 FGFR3 FGFR4 FLT3 FLT3LG FRS2 FRS3 FYN Fgf4 GDNF GFRA1 GFRA2 GFRA3 GFRA4 GRB2 HBEGF HBGF-1 HGF IL-2 IL2 IL2RA IL2RG IL3 IL3RA IL5 IL5RA IRS1 IRS2 JAK1 JAK2 JAK3 KIT KITLG KL KLB KRAS LAT MAPK1 MAPK3 MET NEFL NRAPGEP NRAS NRG1 NRG2 NRG3 NRTN ODAD3 PDGFA PDGFB PDGFRA PDGFRB PDZGEF1 PEA15 PIK3CA PIK3CB PIK3R1 PIK3R2 PRKM1 PTK2 PTPRA RALGDS RANBP9 RAPGEF2 RASGEF1A RASGRF1 RASGRF2 RASGRP1 RASGRP3 RASGRP4 RET RGL1 RGL2 RGL3 SCF SHC1 SHC2 SHC3 SOS1 SPTA1 SPTAN1 SPTB SPTBN2 SPTBN4 TEK TGFA TIE-2 TIE2	Bos taurus (cattle)
RAF-independent MAPK1/3 activation	Astrocytic phosphoprotein PEA-15 Dual specificity protein phosphatase 10 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Dual specificity protein phosphatase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase protein-serine/threonine phosphatase protein-serine/threonine phosphatase	A0A3Q1MLC5 A6QLS1 E1B8P9 E1BAA9 F1MEZ2 F1MI99 F1MM08 F1MQM7 P46196 Q0IID7 Q0VCY8 Q2KJ36	DUSP1 DUSP10 DUSP16 DUSP4 DUSP5 DUSP6 DUSP7 DUSP8 DUSP9 ERK2 MAPK1 MAPK3 PEA15 PRKM1	Bos taurus (cattle)
RAC3 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain-containing adapter protein 2 BCR activator of RhoGEF and GTPase C22H3ORF10 protein Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Delta(14)-sterol reductase LBR Delta-like protein Desmoglein 2 Diaphanous related formin 3 EMD protein Endoplasmic reticulum protein 27 FERM domain containing kindlin 2 Family with sequence similarity 62 (C2 domain containing), member A GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 HSPC321 protein Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Neutral amino acid transporter B(0) Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Progesterone receptor membrane component 2 RAC3 protein RNA binding motif protein 39 Rac GTPase activating protein 1 Ragulator complex protein LAMTOR1 Rap guanine nucleotide exchange factor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 5 Rho GTPase activating protein 6 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 3 SLIT and NTRK like family member 5 SLIT-ROBO Rho GTPase activating protein 2 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase TAO3 Starch binding domain 1 Synapse defective Rho GTPase homolog 1 Synaptobrevin homolog YKT6 Synaptosomal-associated protein Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 phosphoinositide 5-phosphatase receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LPH8 A0A3Q1LWV5 A0A3Q1LWZ4 A0A3Q1LXN8 A0A3Q1M0G8 A0A3Q1M4M7 A0A3Q1M7Q3 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6J8 A0A452DHY1 A0A452DIS6 A0JN43 A2VDK6 A4IF90 A5PK69 A6H709 A6QNS3 A6QQV8 A6QQZ7 A7MB21 A8YXX8 E1B7C4 E1B801 E1B876 E1B8X9 E1BAA4 E1BAJ4 E1BBA0 E1BDN7 E1BFF3 E1BGL2 E1BHQ9 E1BI41 E1BIG6 E1BJ31 E1BJP2 E1BLB3 E1BM23 E1BMN2 E1BN47 E1BNR7 E1BPJ7 F1MBY5 F1MFC2 F1MLS2 F1MTN6 F1MWH1 F1MWH8 F1MXR0 F1MXU4 F1N1Q7 F1N348 F1N513 F1N6V1 F1N7Q8 F6QJJ8 F6RWK1 O46521 O46522 P23726 P23727 P79132 Q08E52 Q0IIJ3 Q17QW1 Q17QZ0 Q2KJ93 Q2T9M8 Q3SX08 Q3T000 Q3T0D8 Q5EAD0 Q95JC7	ABI1 ABI2 ABL2 ABR AMIGO2 ARAP2 ARAP3 ARHGAP1 ARHGAP15 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGAP5 ARHGAP6 ASCT2 BAIAP2 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CYBA CYBB CYFIP1 DEPDC1B DIAPH3 DOCK10 DSG2 EMD EPHA2 ERP27 ESYT1 FAM62A FERMT2 GARRE1 GIT1 GIT2 HSPC321 ITGB1 JAG1 LAMTOR1 LBR LMAN1 MCAM MPP7 NCF1 NCF2 NCF4 NCKAP1L NHS NOX1 NOX3 NOXO1 OCRL OPHN1 PAK1 PAK2 PAK4 PGRMC2 PIK3R1 PIK3R2 PREX1 RAC3 RACGAP1 RAPGEF1 RBM39 SLC1A5 SLITRK3 SLITRK5 SNAP23 SRGAP2 STBD1 SWAP70 SYDE1 TAOK3 TFRC TRIO VANGL1 VAV2 VRK2 WASF1 WASF2 YKT6	Bos taurus (cattle)
RAC2 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Ankyrin repeat and LEM domain containing 2 Armadillo repeat containing X-linked 3 BAR/IMD domain containing adaptor protein 2 like 1 BCR activator of RhoGEF and GTPase C22H3ORF10 protein CDC42 effector protein (Rho GTPase binding) 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 1 Dedicator of cytokinesis 2 Dedicator of cytokinesis 3 Dedicator of cytokinesis 4 Delta(14)-sterol reductase LBR Desmoglein 2 Diaphanous related formin 3 EMD protein Family with sequence similarity 62 (C2 domain containing), member A GIT ArfGAP 1 GIT ArfGAP 2 Granule associated Rac and RHOG effector 1 HSPC321 protein IQ motif containing GTPase activating protein 1 Integrin beta Lectin, mannose binding 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Metaxin-1 NCK associated protein 1 like NHS actin remodeling regulator Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Oligophrenin-1 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphoinositide-3-kinase regulatory subunit 3 Phospholipase Progesterone receptor membrane component 2 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase activating protein 1 Ragulator complex protein LAMTOR1 Ras-related C3 botulinum toxin substrate 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 32 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase-activating protein 26 Rho GTPase-activating protein 35 SLIT and NTRK like family member 5 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase TAO3 Sorting and assembly machinery component 50 homolog Starch binding domain 1 Synapse defective Rho GTPase homolog 1 Transferrin receptor protein 1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Vesicle-associated membrane protein-associated protein B non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LKM4 A0A3Q1LLI7 A0A3Q1LNB6 A0A3Q1LPH8 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LWZ4 A0A3Q1LXL8 A0A3Q1M0G8 A0A3Q1M4M7 A0A3Q1M7Q3 A0A3Q1MFB9 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MPX4 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRV3 A0A3Q1MSA1 A0A3Q1MT43 A0A3Q1MT94 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6J8 A0A3Q1NNR4 A0A452DHY1 A0A452DJ82 A0JN43 A2VDK6 A2VDZ9 A6H709 A6QNS3 A6QQV8 A6QQZ7 A8YXX8 E1B7C4 E1B801 E1B876 E1B8X9 E1BAJ4 E1BBD2 E1BE36 E1BGL2 E1BHQ9 E1BI41 E1BIG6 E1BJ31 E1BJP2 E1BLB3 E1BMN2 E1BN47 E1BNR7 F1MC48 F1MDQ5 F1MFC2 F1MIX6 F1MLS2 F1MWH1 F1MXR0 F1MXU4 F1N1Q7 F1N7Q8 F6QJJ8 F6RWK1 O46521 O46522 P23726 P23727 P32871 P79132 Q08DN7 Q08E52 Q17QW1 Q17QZ0 Q2HJ55 Q2KJ93 Q3SX08 Q3T0D8 Q9TU25	ABI1 ABI2 ABR ANKLE2 ARHGAP1 ARHGAP17 ARHGAP26 ARHGAP32 ARHGAP35 ARHGAP39 ARHGAP42 ARHGDIA ARMCX3 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CDC42EP4 CYBA CYBB CYFIP1 DEPDC1B DIAPH3 DOCK1 DOCK10 DOCK2 DOCK3 DOCK4 DSG2 EMD EPHA2 ESYT1 FAM62A GARRE1 GIT1 GIT2 HSPC321 IQGAP1 ITGB1 LAMTOR1 LBR LMAN1 MCAM MPP7 MTX1 NCF1 NCF2 NCF4 NCKAP1L NHS OPHN1 PAK1 PAK2 PAK4 PGRMC2 PIK3CA PIK3R1 PIK3R2 PIK3R3 PLD2 PREX1 RAC2 RACGAP1 RBM39 SAMM50 SLITRK5 STBD1 SWAP70 SYDE1 TAOK3 TFRC TRIO VANGL1 VAPB VAV1 VAV2 VAV3 VRK2 WASF2	Bos taurus (cattle)
RAC1 GTPase cycle	Abl interactor 1 Abl interactor 2 Actin-binding protein WASF1 Actin-binding protein WASF2 Active breakpoint cluster region-related protein Adhesion molecule with Ig like domain 2 Alsin Rho guanine nucleotide exchange factor ALS2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 BAR/IMD domain containing adaptor protein 2 like 1 BAR/IMD domain-containing adapter protein 2 BCR activator of RhoGEF and GTPase C22H3ORF10 protein CDC42 effector protein (Rho GTPase binding) 4 Caveolin-1 Cdc42 effector protein 1 Cell division control protein 42 homolog Chimaerin Chimaerin Cytochrome b-245 heavy chain Cytochrome b-245 light chain Cytoplasmic FMR1-interacting protein Cytoplasmic FMR1-interacting protein DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 1 Dedicator of cytokinesis 2 Dedicator of cytokinesis 3 Dedicator of cytokinesis 4 Dedicator of cytokinesis 5 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Dedicator of cytokinesis 9 Delta(14)-sterol reductase LBR Delta-like protein Diaphanous related formin 3 EMD protein Endoplasmic reticulum protein 27 FERM domain containing kindlin 2 FERM, ARH/RhoGEF and pleckstrin domain protein 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 5 Family with sequence similarity 13 member A Family with sequence similarity 13 member B Family with sequence similarity 62 (C2 domain containing), member A G protein subunit alpha 13 GIT ArfGAP 1 GIT ArfGAP 2 GMIP protein Granule associated Rac and RHOG effector 1 HSPC321 protein IQ motif containing GTPase activating protein 1 IQ motif containing GTPase activating protein 2 IQGAP3 protein Integrin beta Kinectin 1 MAGUK p55 subfamily member 7 MCF.2 cell line derived transforming sequence like MCF.2 cell line derived transforming sequence Melanoma cell adhesion molecule Myosin IXB NADPH oxidase 1 NADPH oxidase 3 NADPH oxidase organizer 1 NCK associated protein 1 like NHS actin remodeling regulator Neuronal guanine nucleotide exchange factor Neutral amino acid transporter B(0) Neutrophil cytosolic factor 1 Neutrophil cytosolic factor 2 Neutrophil cytosolic factor 4 Nischarin Oligophrenin-1 P21 (RAC1) activated kinase 6 Par-6 family cell polarity regulator alpha Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phosphoinositide-3-kinase regulatory subunit 3 Phospholipase Phospholipase Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Pleckstrin homology and RhoGEF domain containing G6 Proto-oncogene vav RNA binding motif protein 39 Rac GTPase activating protein 1 Rac/Cdc42 guanine nucleotide exchange factor 6 Ragulator complex protein LAMTOR1 RalA binding protein 1 Ras protein specific guanine nucleotide releasing factor 2 Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 12 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 22 Rho GTPase activating protein 23 Rho GTPase activating protein 24 Rho GTPase activating protein 25 Rho GTPase activating protein 27 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 32 Rho GTPase activating protein 33 Rho GTPase activating protein 39 Rho GTPase activating protein 42 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 15 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 39 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho/Rac guanine nucleotide exchange factor 18 SH3 domain binding protein 1 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 2 SLIT-ROBO Rho GTPase activating protein 3 SOS Ras/Rac guanine nucleotide exchange factor 1 SOS Ras/Rho guanine nucleotide exchange factor 2 Serine/threonine-protein kinase N1 Serine/threonine-protein kinase PAK 1 Serine/threonine-protein kinase PAK 3 Serine/threonine-protein kinase TAO3 Spermatogenesis associated 13 Synapse defective Rho GTPase homolog 2 Synaptobrevin homolog YKT6 Synaptosomal-associated protein T-cell activation GTPase activating protein TIAM Rac1 associated GEF 2 Transferrin receptor protein 1 Tyrosine-protein kinase Vang-like protein Vav guanine nucleotide exchange factor 2 Vav guanine nucleotide exchange factor 3 Wiskott-Aldrich syndrome protein family member non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase p21 protein (Cdc42/Rac)-activated kinase 4 protein kinase C receptor protein-tyrosine kinase	A0A140T8D2 A0A3Q1LLI7 A0A3Q1LMM5 A0A3Q1LNB6 A0A3Q1LNE2 A0A3Q1LPH8 A0A3Q1LQ45 A0A3Q1LSY0 A0A3Q1LVS2 A0A3Q1LWV5 A0A3Q1LWX5 A0A3Q1LWZ4 A0A3Q1LX25 A0A3Q1LXW7 A0A3Q1M0G8 A0A3Q1M2Q1 A0A3Q1M4A0 A0A3Q1M4M7 A0A3Q1M6Y9 A0A3Q1M7Q3 A0A3Q1MAP3 A0A3Q1MC59 A0A3Q1MD11 A0A3Q1MFB9 A0A3Q1MFP5 A0A3Q1MKI4 A0A3Q1MP86 A0A3Q1MPX4 A0A3Q1MQK6 A0A3Q1MQP9 A0A3Q1MRG4 A0A3Q1MRV3 A0A3Q1MT43 A0A3Q1MT94 A0A3Q1MTW8 A0A3Q1N078 A0A3Q1N6F4 A0A3Q1N6J8 A0A3Q1NNR4 A0A452DHY1 A0A452DIS6 A0A452DJ82 A0JN43 A1A4I4 A2VDK6 A4FV18 A4IF90 A6H709 A6H7H0 A6QNS3 A6QQV8 A6QQZ7 A7MB21 A7YY57 A7Z037 A8YXX8 E1B7C4 E1B801 E1B876 E1B9G8 E1BA03 E1BAA4 E1BBA0 E1BBD2 E1BCC1 E1BDL7 E1BDN7 E1BDY4 E1BFF3 E1BGL2 E1BH05 E1BH51 E1BHQ9 E1BI41 E1BI70 E1BIG6 E1BIM5 E1BJ31 E1BJP2 E1BK77 E1BL56 E1BLB3 E1BM23 E1BMN2 E1BN47 E1BNA6 E1BNR7 E1BNV7 E1BPJ7 E1BPY0 E1BQ24 F1MBM9 F1MC48 F1MCL8 F1MDF3 F1MDQ5 F1MFA5 F1MFC6 F1MFK1 F1MFS4 F1MHI2 F1MIX6 F1MIZ6 F1MJI3 F1MLS2 F1MM72 F1MMB0 F1MQ43 F1MRP8 F1MS60 F1MSF0 F1MSU8 F1MTN6 F1MTR1 F1MUW3 F1MWH1 F1MWH8 F1MWY5 F1MX60 F1MXR0 F1MY55 F1MZM7 F1N1J9 F1N1Q7 F1N2G5 F1N322 F1N348 F1N3L7 F1N657 F1N7C3 F1N7Q8 F6RHP0 F6RWK1 G3N2T3 G3N3C7 G5E580 G5E6P3 G5E6T2 O46521 O46522 P23726 P23727 P32871 P79132 Q08DA6 Q08DB1 Q08DN7 Q08DP6 Q08E52 Q0IIJ3 Q0P5E3 Q0VD41 Q17QW1 Q17QZ0 Q2KJ55 Q2KJ93 Q2T9M8 Q3SX08 Q3T000 Q3T0D8 Q5EAD0 Q95JC7	ABI1 ABI2 ABL2 ABR ALS2 AMIGO2 ARAP1 ARAP2 ARAP3 ARHGAP1 ARHGAP10 ARHGAP12 ARHGAP15 ARHGAP17 ARHGAP20 ARHGAP22 ARHGAP23 ARHGAP24 ARHGAP25 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP32 ARHGAP33 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP42 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP9 ARHGDIA ARHGEF10 ARHGEF11 ARHGEF15 ARHGEF18 ARHGEF19 ARHGEF25 ARHGEF39 ARHGEF5 ARHGEF6 ARHGEF7 ASCT2 BAIAP2 BAIAP2L1 BCR BORG5 BRK1 C22H3ORF10 CAV1 CDC42 CDC42EP1 CDC42EP4 CHN1 CHN2 CYBA CYBB CYFIP1 CYFIP2 DEPDC1B DIAPH3 DLC1 DOCK1 DOCK10 DOCK11 DOCK2 DOCK3 DOCK4 DOCK5 DOCK6 DOCK7 DOCK8 DOCK9 EMD EPHA2 ERP27 ESYT1 FAM13A FAM13B FAM62A FARP1 FARP2 FERMT2 FGD5 GARRE1 GIT1 GIT2 GMIP GNA13 HSPC321 IQGAP1 IQGAP2 IQGAP3 ITGB1 JAG1 KTN1 L2HGDH LAMTOR1 LBR MCAM MCF2L MPP7 MYO9B NCF1 NCF2 NCF4 NCKAP1L NGEF NHS NISCH NOX1 NOX3 NOXO1 OPHN1 PAK1 PAK2 PAK3 PAK4 PAK5 PAK6 PARD6A PIK3CA PIK3R1 PIK3R2 PIK3R3 PKN PKN1 PKN2 PLD1 PLD2 PLEKHG1 PLEKHG2 PLEKHG3 PLEKHG6 PREX1 PREX2 PRK1 PRKCL1 RACGAP1 RALBP1 RASGRF2 RBM39 SH3BP1 SLC1A5 SNAP23 SOS1 SOS2 SPATA13 SRGAP1 SRGAP2 SRGAP3 SWAP70 SYDE2 TAGAP TAOK3 TFRC TIAM2 TRIO VANGL1 VAV1 VAV2 VAV3 VRK2 WASF1 WASF2 WASF3 YKT6	Bos taurus (cattle)
Pyroptosis	Apoptosis regulator BAX BCL2-antagonist/killer 1 CHMP4B protein Caspase 1 Caspase-13 Caspase-3 Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4a Charged multivesicular body protein 7 Chromatin modifying protein 4C Chromatin modifying protein 6 Cytochrome c Elastase, neutrophil expressed Gasdermin D Gasdermin E Granzyme B High mobility group protein B1 Interleukin-1 alpha Interleukin-18 Multifunctional fusion protein	A0A140T838 A0A3Q1MD51 A0A3Q1MFA5 A2VDY3 A6H704 E1BFC3 F1MB04 F1MTF4 G3MWP1 O02703 O75601 P08831 P10103 P62894 Q05KI7 Q08E32 Q148L0 Q2HJ35 Q3SX42 Q3T0U5 Q58CS7 Q9TU73	BAK1 BAX CASP1 CASP13 CASP3 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP6 CHMP7 CYC CYCS ELANE GSDMD GSDME GZMB HMG1 HMGB1 IGIF IL18 IL1A IL1B VPS24	Bos taurus (cattle)
Prostanoid ligand receptors	Prostaglandin D2 receptor 2 Prostaglandin D2 receptor Prostaglandin E receptor 1 Prostaglandin E receptor 2 Prostaglandin E2 receptor EP3 subtype Prostaglandin E2 receptor EP4 subtype Prostaglandin F2-alpha receptor Prostaglandin I2 receptor Thromboxane A2 receptor	A0A140T8B9 A0A3Q1N2W9 A0A452DI56 E1BQ27 F1MUY4 F1MZJ8 F1N2L8 P34979 Q95125	PTGDR PTGDR2 PTGER1 PTGER2 PTGER3 PTGER4 PTGFR PTGIR TBXA2R	Bos taurus (cattle)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A3Q1MKX0 E1B7B0 E1BNG2	MAN1A1 MAN1A2 MAN1C1	Bos taurus (cattle)	G70323CJ

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