GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **226 - 250** of **268** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin, lysosomal cystine transporter Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A0A8I3N947 A0A8I3NY92 A0A8I3P1B2 A0A8I3P4E1 A0A8I3PQ76 A0A8I3Q823 A0A8I3RSG2 Q9N280	CTNS GLAST SLC1A1 SLC1A2 SLC1A3 SLC1A6 SLC1A7 SLC25A26 SLC32A1	Canis familiaris (dog)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta MEFV innate immunity regulator, pyrin NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor PYD and CARD domain containing Pannexin Proline-serine-threonine phosphatase interacting protein 1 Thioredoxin-interacting protein Thioredoxin Uncharacterized protein	A0A8I3N9V3 A0A8I3ND03 A0A8I3NKV1 A0A8I3P020 A0A8I3PDQ2 A0A8I3PGK7 A0A8I3PV78 A0A8I3RQW6 A0A8I3RXE3 A0A8I3RYZ8	HSP90AB1 MEFV NLRP3 P2RX7 PANX PANX1 PSTPIP1 PYCARD SUGT1 TXN TXNIP	Canis familiaris (dog)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Beta-1,4-N-acetyl-galactosaminyltransferase 2 Uromodulin	A0A8I3NAX8 A0A8I3NFY5 A0A8I3P3P6 A0A8I3PA45	ASGR1 ASGR2 B4GALNT2 UMOD	Canis familiaris (dog)
Vitamin B2 (riboflavin) metabolism	FAD synthase Riboflavin transporter Riboflavin transporter Tartrate-resistant acid phosphatase type 5 Uncharacterized protein riboflavin kinase	A0A8I3NBD2 A0A8I3NDY6 A0A8I3P1H5 A0A8I3RQK2 A0A8I3S1B1 E2RBY6	ACP5 ENPP1 FLAD1 RFK SLC52A2 SLC52A3	Canis familiaris (dog)
Insulin receptor signalling cascade	Growth factor receptor bound protein 10 Growth factor receptor bound protein 2 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A8I3NBK6 A0A8I3NUU1 A0A8I3PT69 A0A8I3PWD4 A0A8I3S3D9 P01321	GRB10 GRB2 INS INSR SHC1 SOS1	Canis familiaris (dog)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A8I3NF57 A0A8I3Q6M3 A0A8I3RVT4	MAN1A1 MAN1A2 MAN1C1	Canis familiaris (dog)	G70323CJ
MET activates RAP1 and RAC1	Adapter molecule crk CRK like proto-oncogene, adaptor protein Dedicator of cytokinesis 7 GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Rap guanine nucleotide exchange factor 1 Ras-related C3 botulinum toxin substrate 1 Ras-related C3 botulinum toxin substrate 1 small monomeric GTPase small monomeric GTPase	A0A8I3NGQ0 A0A8I3NGY1 A0A8I3NH46 A0A8I3NUL4 A0A8I3NXI8 A0A8I3P5F5 A0A8I3PN08 A0A8I3PT69 A0A8I3RSH7 A0A8I3RUF3 P62999 Q867B7	CRK CRKL DOCK7 GAB1 GRB2 HGF MET RAC1 RAP1A RAP1B RAPGEF1	Canis familiaris (dog)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A8I3NGY1 A0A8I3NXI8 A0A8I3PMT9 A0A8I3PT69 Q867B7	GAB1 GRB2 HGF MET PTPN11	Canis familiaris (dog)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription	A0A8I3NGY1 A0A8I3RV66 Q867B7	HGF MET STAT3	Canis familiaris (dog)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	A0A8I3NGY1 Q867B7	HGF MET	Canis familiaris (dog)
TNFR1-mediated ceramide production	Neutral sphingomyelinase activation associated factor Small ribosomal subunit protein RACK1 TNFR-Cys domain-containing protein Tumor necrosis factor sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A8I3NH12 A0A8I3NK36 A0A8I3Q3L1 A0A8I3QLC7 A0A8I3RSQ2 P51742	NSMAF RACK1 SMPD2 SMPD3 TNF TNFA TNFRSF1A TNFSF2	Canis familiaris (dog)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3NVW9 A0A8I3PAR4 A0A8I3RQ77 A0A8I3S0I1 P33712	IGF1 IGF1R IGF2 IGFIA IRS1 IRS2 IRS4	Canis familiaris (dog)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor I Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A8I3NI15 A0A8I3RQ77 A0A8I3S512 P33712	CILP IGF1 IGF1R IGF2 IGFIA	Canis familiaris (dog)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensin-converting enzyme Angiotensinogen Carboxylesterase 5A Carboxypeptidase B1 Carboxypeptidase B2 Cathepsin D Cathepsin G Chymase Neprilysin Renin receptor Renin cathepsin X	A0A8I3NK04 A0A8I3NT46 A0A8I3P176 A0A8I3PJS4 A0A8I3PTV1 A0A8I3QCM1 A0A8I3RP60 A0A8I3RR88 A0A8I3RUJ7 A0A8I3S392 F5C3N2 P21842 Q4LAL9 Q6DYE7	ACE ACE2 AGT ATP6AP2 CES5A CMA1 CPA3 CPB2 CTSD CTSG CTSZ ENPEP MME REN	Canis familiaris (dog)
Class A/1 (Rhodopsin-like receptors)	Cannabinod receptor Chemerin-like receptor 1 G protein-coupled receptor 183 G protein-coupled receptor 35 G protein-coupled receptor 55 G protein-coupled receptor 68 G-protein coupled bile acid receptor 1 Melatonin receptor 1B Melatonin receptor type 1A N-arachidonyl glycine receptor Oxoglutarate receptor 1 Platelet-activating factor receptor Succinate receptor 1 Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A8I3NKP7 A0A8I3P831 A0A8I3P8G7 A0A8I3PBK9 A0A8I3PDW8 A0A8I3PE74 A0A8I3PH14 A0A8I3PIK0 A0A8I3PZA6 A0A8I3Q1X3 A0A8I3Q2D1 A0A8I3QYW7 A0A8I3RTK7 A0A8I3RY80 A0A8I3S3R7 E2RKA3	CB2 CMKLR1 CNR2 GPBAR1 GPR132 GPR18 GPR183 GPR35 GPR39 GPR55 GPR68 HCAR2 MTNR1A MTNR1B OXGR1 PTAFR SUCNR1	Canis familiaris (dog)
Sensory perception of sweet, bitter, and umami (glutamate) taste	Bitter taste receptor T2R43 G protein subunit alpha transducin 3 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste receptor type 1 member 3 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A8I3NKU5 A0A8I3PJF2 A0A8I3PQY2 A0A8I3PRQ9 A0A8I3Q2P2 A0A8I3Q7L4 A0A8I3QV74 A0A8I3S925 A0A8I3S929 A0A8I3SCV7 P62872 P79147 Q2ABD0 Q2ABD1 Q2ABD4 Q2ABD5 Q2ABD6 Q2ABD8 Q2ABE0	CAFA-T2R43 GNAT3 GNB1 GNB3 GNG13 ITPR3 LOC100682759 TAS1R1 TAS1R3 TAS2R1 TAS2R10 TAS2R3 TAS2R38 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R5 TAS2R7	Canis familiaris (dog)	G58161NS
Relaxin receptors	Insulin-like 3 Relaxin 2 Relaxin family peptide receptor 1 Relaxin family peptide receptor 3 Relaxin receptor 2 Relaxin-3	A0A8I3NLX3 A0A8I3PPP9 A0A8I3RPW6 A0A8I3RZ39 Q5XM32 Q6X7V3	INSL3 LGR8 RLF RLN2 RLN3 RXFP1 RXFP2 RXFP3	Canis familiaris (dog)
Assembly and cell surface presentation of NMDA receptors	Glutamate receptor ionotropic, NMDA 1 Glutamate receptor ionotropic, NMDA 2B Glutamate receptor Glutamate receptor Glutamate receptor Glutamate receptor	A0A8I3NNK2 A0A8I3NRD6 A0A8I3P9B8 A0A8I3RRH4 Q5R1P0 Q5R1P3	GRIN1 GRIN2A GRIN2B GRIN2C GRIN2D GRIN3A NMDAR1	Canis familiaris (dog)
Synthesis, secretion, and deacylation of Ghrelin	1-alkyl-2-acetylglycerophosphocholine esterase Appetite-regulating hormone Carboxylic ester hydrolase Glucagon Insulin-like growth factor I Insulin Leptin Membrane bound O-acyltransferase domain containing 4 Neuroendocrine convertase 1 Signal peptidase complex catalytic subunit SEC11A Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin Uncharacterized protein	A0A8I3NP76 A0A8I3PBA0 A0A8I3PYH6 A0A8I3QXE0 A0A8I3RR59 A0A8I3RXD7 A0A8I3S964 P01321 P33711 P33712 P61008 P67811 P83362 Q28250 Q9BEF8	BCHE GCG GH GH1 GHRL IGF1 IGFIA INS LEP MBOAT4 MTLRP PCSK1 PLA2G7 SEC11A SEC11L1 SPC12 SPC18 SPC22 SPC25 SPCS1 SPCS2 SPCS3	Canis familiaris (dog)	G58161NS
Platelet homeostasis	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Platelet-activating factor acetylhydrolase	A0A8I3NPN3 A0A8I3NX68 A0A8I3P313 A0A8I3PPB8 A0A8I3PV78 A0A8I3Q0A9 A0A8I3QCF1 A0A8I3S3K0	P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 PAFAH2	Canis familiaris (dog)
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 Slit guidance ligand 2	A0A8I3NQC4 Q9TSZ6	DAG1 SLIT2	Canis familiaris (dog)
Apoptotic execution phase	B-cell receptor-associated protein Caspase 8 Dynamin-1-like protein Dynamin-1-like protein non-specific serine/threonine protein kinase	A0A8I3NR52 A0A8I3PR10 A0A8I3Q0S5 A0A8I3S1Q3 Q38JA9	BCAP31 CASP8 DNM1L LOC119868890 STK24	Canis familiaris (dog)
Lactose synthesis	Beta-1,4-galactosyltransferase Lactose synthase B protein Solute carrier family 2, facilitated glucose transporter member 1	A0A8I3NRK7 A0A8I3S1K5 F1PTQ7	B4GALT1 LALBA LYZG SLC2A1	Canis familiaris (dog)	G58161NS G74621DY
TWIK-related alkaline pH activated K+ channel (TALK)	Potassium two pore domain channel subfamily K member 16 Potassium two pore domain channel subfamily K member 17	A0A8I3NSP8 A0A8I3NUY1	KCNK16 KCNK17	Canis familiaris (dog)
Fructose biosynthesis	Aldo-keto reductase family 1 member B1 Sorbitol dehydrogenase	A0A8I3P2L6 A0A8I3QI05	AKR1B1 SORD	Canis familiaris (dog)	G58161NS

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