GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **268** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
Uptake of dietary cobalamins into enterocytes	ATP binding cassette subfamily D member 4 Chymotrypsinogen 2 Cobalamin binding intrinsic factor Lysosomal cobalamin transport escort protein LMBD1 Transcobalamin-like C-terminal domain-containing protein trypsin	A0A8I3N584 A0A8I3P9U6 A0A8I3PD99 A0A8I3S4Z0 P04813 Q5XWD5	CBLIF CTRB CTRB1 GIF LMBRD1 LOC119869278 PRSS2 TCN1	Canis familiaris (dog)
Digestion	Alkaline phosphatase Guanylate cyclase activator 2B Guanylate cyclase Guanylin Pirin	A0A8I3N4X7 A0A8I3P3W4 A0A8I3PB32 A0A8I3PK10 A0A8I3QK41	ALPI GUCA2A GUCA2B GUCY2C PIR	Canis familiaris (dog)
N-glycan trimming and elongation in the cis-Golgi	Glycoprotein endo-alpha-1,2-mannosidase	A0A8I3N4I9	MANEA	Canis familiaris (dog)	G58161NS
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A8I3N3U3 A0A8I3NGY1 A0A8I3NUU1 A0A8I3PS27 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3QSS9 A0A8I3S3D9 Q867B7	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Canis familiaris (dog)
Metal ion SLC transporters	Copper transport protein Hephaestin Natural resistance-associated macrophage protein 1 Solute carrier family 11 member 2 Solute carrier family 30 member 10 Solute carrier family 40 protein member 1 Solute carrier family 41 member Solute carrier family 41 member ferroxidase	A0A8I3N3B2 A0A8I3N4Y2 A0A8I3PMF7 A0A8I3PWM1 A0A8I3PXW9 A0A8I3Q213 A0A8I3QCU8 A0A8I3RZ10 E2RFJ3	CP HEPH SLC11A1 SLC11A2 SLC30A10 SLC31A1 SLC40A1 SLC41A1 SLC41A2	Canis familiaris (dog)
Synthesis of bile acids and bile salts	Cytochrome P450 family 7 subfamily A member 1 Cytochrome P450 family 7 subfamily B member 1 Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Oxysterol-binding protein Retinoic acid receptor RXR	A0A8I3N2S7 A0A8I3NA48 A0A8I3NIH7 A0A8I3NPK5 A0A8I3NS93 A0A8I3P033 A0A8I3P4G5 A0A8I3PNT4 A0A8I3PRC4 A0A8I3PYI4 A0A8I3S236 A0A8I3S5H8 A0A8I3SAZ3	CYP7A1 CYP7B1 NCOA1 NCOA2 NR1H4 OSBP OSBPL1A OSBPL2 OSBPL3 OSBPL6 OSBPL7 OSBPL9 RXRA	Canis familiaris (dog)
The activation of arylsulfatases	Arylsulfatase A Arylsulfatase B Arylsulfatase F Arylsulfatase G Arylsulfatase K Arylsulfatase L Arylsulfatase family member H Arylsulfatase family member I Arylsulfatase family member J Steroid sulfatase Sulfatase modifying factor 1 Sulfatase modifying factor 2	A0A8I3N2H8 A0A8I3NK85 A0A8I3NQ68 A0A8I3PN86 A0A8I3PP93 A0A8I3PPB0 A0A8I3PT92 A0A8I3Q0D0 A0A8I3Q695 A0A8I3S3Z3 Q32KH0 Q32KI4	ARSA ARSB ARSF ARSG ARSH ARSI ARSJ ARSK ARSL STS SUMF1 SUMF2 arsb	Canis familiaris (dog)
Trafficking and processing of endosomal TLR	Canopy FGF signaling regulator 3 Cathepsin B Cathepsin S Endoplasmin Legumain Procathepsin L Toll like receptor 3 Toll like receptor 7 Toll like receptor 8 Toll-like receptor 9 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A8I3N2H5 A0A8I3NCE8 A0A8I3P6K4 A0A8I3P8U9 A0A8I3P903 A0A8I3PZY7 A0A8I3Q7B4 A0A8I3S0M3 A0A8I3SBE6 P41148 Q5I2M8 Q9GL24	CNPY3 CTSB CTSL CTSL1 CTSS GRP94 HSP90B1 HSPC4 LGMN TLR3 TLR7 TLR8 TLR9 TRA1 UNC93B1	Canis familiaris (dog)
Removal of aminoterminal propeptides from gamma-carboxylated proteins	Coagulation factor IX Coagulation factor VII Coagulation factor X Growth arrest specific 6 Osteocalcin Prothrombin Vitamin K-dependent protein C Vitamin K-dependent protein S furin	A0A8I3N1T9 A0A8I3N921 A0A8I3PQV5 A0A8I3PUT1 A0A8I3Q1K1 A0A8I3QAV8 A0A8I3S489 A0A8I3SCE7 Q28278	BGLAP F10 F2 F7 F9 FURIN GAS6 PROC PROS1	Canis familiaris (dog)
Transport of RCbl within the body	ATP binding cassette subfamily D member 4 CD320 molecule LDL receptor related protein 2 Low density lipoprotein receptor adaptor protein 1 Lysosomal cobalamin transport escort protein LMBD1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Transcobalamin-2 Transcobalamin-like C-terminal domain-containing protein	A0A8I3N1I8 A0A8I3N584 A0A8I3NS16 A0A8I3P9U6 A0A8I3PAV5 A0A8I3PKW5 A0A8I3Q758 A0A8I3S4Z0 Q6UR05	ABCC1 CD320 LDLRAP1 LMBRD1 LOC119869278 LRP2 MRP1 TCN1 TCN2	Canis familiaris (dog)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 3 Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin Short-wave-sensitive opsin 1	A0A8I3N0P5 A0A8I3NDC4 A0A8I3PJU6 A0A8I3Q2S6 A0A8I3QE57 A0A8I3RTH5 E2R3W5 O18914	OPN1LW OPN1SW OPN3 OPN4 OPN5 RCP RGR RHO RRH	Canis familiaris (dog)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A8I3N0E0 A0A8I3N240 A0A8I3N9K8 A0A8I3PDQ2 A0A8I3QZQ9	GJA10 GJC1 GJD2 PANX PANX1 PANX2	Canis familiaris (dog)
Platelet Adhesion to exposed collagen	ADAM metallopeptidase with thrombospondin type 1 motif 13 High affinity immunoglobulin epsilon receptor subunit gamma Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein von Willebrand factor von Willebrand factor	A0A8I3N060 A0A8I3NAX6 A0A8I3P3X1 A0A8I3PUN0 A0A8I3QSK6 A0A8I3SCK0 Q28295	ADAMTS13 F8VWF FCER1G FYN GP6 LYN VWF	Canis familiaris (dog)
Arachidonic acid metabolism	Acyltransferase Phospholipase A2 fatty acid amide hydrolase	A0A8I3MZB9 A0A8I3P542 A0A8I3Q562	DGAT2L6 FAAH PLA2G4A	Canis familiaris (dog)
Hydrolysis of LPC	Lysosomal phospholipase A and acyltransferase Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase B-like	A0A8I3MZB9 A0A8I3P3G6 A0A8I3P464 A0A8I3PKA9 A0A8I3QXI0 A0A8I3RZX3 Q6XPZ3	LYPLA3 PLA2G15 PLA2G4A PLA2G4B PLA2G4D PLA2G4E PLA2G4F PLBD1	Canis familiaris (dog)
Class B/2 (Secretin family receptors)	Adhesion G protein-coupled receptor E1 Adhesion G protein-coupled receptor E3 Adhesion G protein-coupled receptor E5 Corticoliberin Corticotropin releasing hormone receptor 2 Corticotropin-releasing factor receptor 1 Corticotropin-releasing factor-binding protein Parathyroid hormone 2 receptor Parathyroid hormone-related protein Parathyroid hormone/parathyroid hormone-related peptide receptor Parathyroid hormone Sushi domain-containing protein Tuberoinfundibular peptide of 39 residues Uncharacterized protein Uncharacterized protein Urocortin	A0A8I3MZB5 A0A8I3P6W0 A0A8I3P7R9 A0A8I3PCJ2 A0A8I3PCP1 A0A8I3PHA9 A0A8I3PPK6 A0A8I3PPW2 A0A8I3RQ73 A0A8I3RSJ3 A0A8I3RVU2 A0A8I3RXL4 P52211 P52212 Q2Q423 Q9TU31	ADGRE1 ADGRE3 ADGRE5 CD55 CRH CRHBP CRHR1 CRHR2 LOC484897 PTH PTH1 PTH1R PTH2 PTH2R PTHLH PTHR1 UCN UCN3	Canis familiaris (dog)
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A8I3MYT1 A0A8I3N9C7 A0A8I3ND97 A0A8I3PVZ3 A0A8I3RTT3	ABCC5 CEMIP HAS1 HAS2 HAS3	Canis familiaris (dog)	G35674CY
Phase 3 - rapid repolarisation	Potassium voltage-gated channel subfamily A member 5 Potassium voltage-gated channel subfamily E member 1 Potassium voltage-gated channel subfamily E member 2 Potassium voltage-gated channel subfamily E regulatory subunit 3 Potassium voltage-gated channel subfamily E regulatory subunit 5 Potassium voltage-gated channel subfamily H member 2 Uncharacterized protein	A0A8I3MYQ7 A0A8I3P4I4 A0A8I3PKK9 A0A8I3PME7 A0A8I3PYI8 A0A8I3SCN1 Q9TSZ3	CERG ERG KCNA5 KCNE2 KCNE3 KCNE4 KCNE5 KCNH2	Canis familiaris (dog)
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dolichyl-phosphate-mannose--protein mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 LARGE xylosyl- and glucuronyltransferase 2 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase	A0A8I3MY95 A0A8I3N4J0 A0A8I3NBQ3 A0A8I3NME9 A0A8I3NRN3 A0A8I3P5F6 A0A8I3P946 A0A8I3QJ22 Q5NDE9 Q9TSZ6	AGO61 B3GALNT2 B4GAT1 DAG1 GTDC2 LARGE1 LARGE2 POMGNT1 POMGNT2 POMK POMT1 POMT2	Canis familiaris (dog)
IFNG signaling activates MAPKs	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein	A0A8I3MY73 A0A8I3NVH4 A0A8I3PZA0 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 RAF1	Canis familiaris (dog)
Interferon gamma signaling	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Y-box-binding protein 1 Y-box-binding protein 1 Y-box-binding protein 1 calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A8I3MY73 A0A8I3NIS8 A0A8I3NMP2 A0A8I3NPS8 A0A8I3NU62 A0A8I3NVH4 A0A8I3NXV5 A0A8I3PF62 A0A8I3PSA1 A0A8I3PWC6 A0A8I3PZJ7 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 A0A8I3RWC7 P42161	CAMK2A CAMK2B CAMK2G IFNG IFNGR1 IFNGR2 JAK1 JAK2 LOC479011 MAPK1 MAPK3 PRKCD PTPN6 SOCS3 STAT1 YBX1	Canis familiaris (dog)
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
CS/DS degradation	Alpha-L-iduronidase Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase Beta-hexosaminidase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase Iduronate 2-sulfatase Neurocan Versican core protein	A0A8I3MXW0 A0A8I3MY15 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NUF9 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3PI48 A0A8I3PNW9 Q01634 Q29393 Q32KH3 Q32KI4	ARSB BCAN BGN CSPG4 CSPG5 DCN DCN1C HEXA HEXB HYAL1 IDS IDUA NCAN VCAN arsb ids	Canis familiaris (dog)	G27025MB
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Arachidonate 5-lipoxygenase Leukotriene C4 synthase Paraoxonase 3 Paraoxonase Paraoxonase	A0A8I3MWD6 A0A8I3PAM3 A0A8I3PDD9 A0A8I3PDF6 A0A8I3PDS2 A0A8I3SA30	ALOX5 ALOX5AP LTC4S PON1 PON2 PON3	Canis familiaris (dog)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Toll-like receptor 9 Toll-like receptor 9 Uncharacterized protein non-specific serine/threonine protein kinase	A0A8I3MWD3 A0A8I3PJ50 A0A8I3PZW3 A0A8I3Q7B4 A0A8I3QFN1 Q5I2M8	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Canis familiaris (dog)

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