GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **151 - 175** of **268** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▲	GlyTouCan ID
Post-translational protein phosphorylation	Albumin Alpha 1 antitrypsin Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A Alpha-2-HS-glycoprotein Alpha-L-fucosidase Alpha-fetoprotein Ameloblastin Amelogenin X isoform Amelotin Amyloid beta precursor like protein 2 Amyloid-beta A4 protein Anoctamin Antithrombin-III Apolipoprotein A-I Apolipoprotein A-II Apolipoprotein A-V Apolipoprotein B Apolipoprotein E Apolipoprotein L3 Apolipoprotein L3 BPI fold containing family B member 2 Bone morphogenetic protein 4 C4a anaphylatoxin CCN family member 1 Cadherin-2 Calumenin Chordin like 1 Coagulation factor V Complement C3 Cytoskeleton associated protein 4 Dentin matrix acidic phosphoprotein 1 Disintegrin and metalloproteinase domain-containing protein 10 DnaJ homolog subfamily C member 3 Enamelin Endoplasmin FAM20 C-terminal domain-containing protein FAM20A golgi associated secretory pathway pseudokinase Fibrillin 1 Fibrinogen alpha chain Fibroblast growth factor 23 Fibronectin Follistatin like 3 Follistatin-related protein 1 Galectin 1 Glypican-3 Golgi membrane protein 1 Growth arrest specific 6 Histidine rich calcium binding protein Insulin like growth factor binding protein 7 Insulin-like growth factor-binding protein 3 Insulin-like growth factor-binding protein 4 Insulin-like growth factor-binding protein 5 Inter-alpha-trypsin inhibitor heavy chain 2 Interleukin-6 Kinectin 1 Kininogen 1 Latent transforming growth factor beta binding protein 1 MIA SH3 domain ER export factor 3 Macrophage colony-stimulating factor 1 Matrilin 3 Matrix extracellular phosphoglycoprotein Matrix remodeling-associated protein 8 Melanotransferrin Membrane bound transcription factor peptidase, site 1 Menin Metalloproteinase inhibitor 1 Milk fat globule EGF and factor V/VIII domain containing Multiple EGF like domains 6 Nucleobindin-1 Patatin like phospholipase domain containing 2 Proenkephalin-A Protein disulfide-isomerase A6 Protein disulfide-isomerase Protein kinase C substrate 80K-H Reticulocalbin 1 SPARC like 1 Secreted phosphoprotein 1 Secreted phosphoprotein 24 Secretogranin-1 Secretogranin-2 Secretogranin-3 Serine protease Serpin family D member 1 Stanniocalcin-2 Sulfhydryl oxidase Tenascin C Trans-golgi network protein 2 Transmembrane protein 132A Uncharacterized protein Uncharacterized protein Uncharacterized protein VGF nerve growth factor inducible Versican core protein Vitamin K-dependent protein C [Wnt protein] O-palmitoleoyl-L-serine hydrolase ferroxidase von Willebrand factor A domain-containing protein 1	A0A0B4J199 A0A8I3MBU3 A0A8I3MBV3 A0A8I3MD84 A0A8I3MKS3 A0A8I3MKU0 A0A8I3MLH1 A0A8I3MRY5 A0A8I3MSG4 A0A8I3MSR8 A0A8I3MVA9 A0A8I3MY68 A0A8I3MZB7 A0A8I3N0D8 A0A8I3N1E6 A0A8I3N365 A0A8I3N3Q6 A0A8I3N5X9 A0A8I3N8F9 A0A8I3N8K1 A0A8I3N8X3 A0A8I3NA54 A0A8I3NAE2 A0A8I3NAG2 A0A8I3NBG6 A0A8I3NBI4 A0A8I3NBI7 A0A8I3NFV4 A0A8I3NH95 A0A8I3NHN1 A0A8I3NHZ1 A0A8I3NIA5 A0A8I3NLT2 A0A8I3NN59 A0A8I3NPQ9 A0A8I3NQA0 A0A8I3NR35 A0A8I3NSE7 A0A8I3NTU0 A0A8I3NXQ1 A0A8I3NY94 A0A8I3P0M4 A0A8I3P1E4 A0A8I3P1V2 A0A8I3P1W2 A0A8I3P261 A0A8I3P2Y2 A0A8I3P735 A0A8I3P7V0 A0A8I3P874 A0A8I3P9H6 A0A8I3PA47 A0A8I3PB34 A0A8I3PED8 A0A8I3PI20 A0A8I3PIK8 A0A8I3PM36 A0A8I3PMB5 A0A8I3PMF7 A0A8I3PPY1 A0A8I3PSD1 A0A8I3PTJ6 A0A8I3PTU8 A0A8I3PU47 A0A8I3PWU3 A0A8I3Q0F7 A0A8I3Q0M1 A0A8I3Q1K1 A0A8I3Q1Q3 A0A8I3Q2P4 A0A8I3Q2T3 A0A8I3Q4H4 A0A8I3Q662 A0A8I3QBE2 A0A8I3QN81 A0A8I3QNP3 A0A8I3RP80 A0A8I3RQL9 A0A8I3RRH5 A0A8I3RT41 A0A8I3RYZ7 A0A8I3S0I3 A0A8I3S0P1 A0A8I3S3D7 A0A8I3S4D1 A0A8I3S5B1 A0A8I3S6A4 A0A8I3S8V0 A0A8I3S915 A1ILJ0 A2SXS5 E2RAK7 F6PLF2 J9PBH8 P18649 P41148 Q28278	ADAM10 AFP AHSG ALB AMBN AMELX AMTN ANO8 APLP2 APOA1 APOA2 APOA5 APOB APOE APP BMP15 BMP4 BPIFB2 C3 CALU CCN1 CDH2 CHGB CHRDL1 CKAP4 COA5 CP CSF1 DMP1 DNAJC3 ENAM F5 FAM20A FAM20C FBN1 FGA FGF23 FGF8B FN1 FSTL1 FSTL3 FUCA2 GAS6 GOLM1 GPC3 GRP94 HRC HSP90B1 HSPC4 IGFBP3 IGFBP4 IGFBP5 IGFBP7 IL6 ITIH2 KNG1 KTN1 LGALS1 LOC102156332 LOC481722 LOC607874 LTBP1 MATN3 MBTPS1 MEGF6 MELTF MEN1 MEPE MFGE8 MIA3 MXRA8 NOTUM NUCB1 P4HB PDIA6 PENK PNPLA2 PRKCSH PROC PRSS23 QSOX1 RCN1 SCG2 SCG3 SERPINA1 SERPINC1 SERPIND1 SPARCL1 SPP1 SPP2 STC2 TGOLN2 TIMP1 TMEM132A TNC TRA1 VCAN VGF VWA1 WFS1	Canis familiaris (dog)
SHC-mediated cascade:FGFR1	Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Klotho Multifunctional fusion protein SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A0B4J199 A0A7U3JWB8 A0A8I3MP09 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NUU1 A0A8I3NV07 A0A8I3NYK3 A0A8I3PJY6 A0A8I3PSP7 A0A8I3PT69 A0A8I3PZB5 A0A8I3Q1I3 A0A8I3S3D9 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 Q20FD0	FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 GRB2 HRAS KL KRAS NRAS SHC1 SOS1	Canis familiaris (dog)
MHC class II antigen presentation	ADP-ribosylation factor AP complex subunit beta AP complex subunit sigma AP complex subunit sigma AP-1 complex subunit mu-1 AP-1 complex subunit mu-2 AP-2 complex subunit alpha AP-2 complex subunit alpha AP-2 complex subunit mu AP-2 complex subunit sigma Actin related protein 10 Actin related protein 1B Alpha-centractin CD74 molecule Calnexin Carboxypeptidase Cathepsin B Cathepsin D Cathepsin E Cathepsin F Cathepsin O Cathepsin S Centromere protein E Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain domain-containing protein Clathrin heavy chain Clathrin light chain Cytoplasmic dynein 1 intermediate chain 2 Dipeptidyl peptidase 1 Dynactin subunit 1 Dynactin subunit 2 Dynactin subunit 3 Dynactin subunit 4 Dynactin subunit 5 Dynactin subunit 6 Dynein cytoplasmic 1 heavy chain 1 Dynein cytoplasmic 1 intermediate chain 1 Dynein light chain Dynein light chain Dynein light intermediate chain Dynein light intermediate chain F-actin-capping protein subunit alpha-2 F-actin-capping protein subunit alpha F-actin-capping protein subunit alpha F-actin-capping protein subunit beta GTP-binding protein SAR1b Gamma-interferon-inducible lysosomal thiol reductase HLA class II histocompatibility antigen, DO alpha chain-like Kinesin associated protein 3 Kinesin family member 11 Kinesin family member 26A Kinesin family member 4A Kinesin family member 5A Kinesin light chain Kinesin light chain Kinesin light chain Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Kinesin-like protein Legumain Lymphocyte activating 3 MHC class II DR alpha chain MHC class II antigen DM beta Major histocompatibility complex, class II, DM alpha Major histocompatibility complex, class II, DQ alpha 1 Major histocompatibility complex, class II, DQ beta 2 Oxysterol-binding protein Pro-cathepsin H Procathepsin L Protein SEC13 homolog Protein transport protein SEC23 Protein transport protein Sec31A Queuine tRNA-ribosyltransferase catalytic subunit 1 Rab interacting lysosomal protein Rac GTPase activating protein 1 Ras-related protein Rab-7a SEC24 homolog A, COPII coat complex component SEC24 homolog B, COPII coat complex component SEC24 homolog C, COPII coat complex component SEC24 homolog D, COPII coat complex component SH3 domain containing GRB2 like 2, endophilin A1 Spectrin beta chain Uncharacterized protein Uncharacterized protein dynamin GTPase dynamin GTPase	A0A8I3MB83 A0A8I3MEF2 A0A8I3MGM6 A0A8I3MHS5 A0A8I3MQ01 A0A8I3MQ56 A0A8I3MSD7 A0A8I3MX81 A0A8I3MZR3 A0A8I3N2P7 A0A8I3N366 A0A8I3N413 A0A8I3N448 A0A8I3N536 A0A8I3N796 A0A8I3N7P9 A0A8I3N9C4 A0A8I3NBU3 A0A8I3NCI2 A0A8I3NCU8 A0A8I3NF50 A0A8I3NFH8 A0A8I3NH94 A0A8I3NHB2 A0A8I3NHV2 A0A8I3NIZ3 A0A8I3NMB7 A0A8I3NMT0 A0A8I3NPI1 A0A8I3NPK5 A0A8I3NPS2 A0A8I3NRM5 A0A8I3NTK0 A0A8I3NTV2 A0A8I3NUM0 A0A8I3NWA9 A0A8I3NX29 A0A8I3NYK0 A0A8I3NZH7 A0A8I3P2D4 A0A8I3P3K7 A0A8I3P4A1 A0A8I3P503 A0A8I3P5K8 A0A8I3P5S6 A0A8I3P8U9 A0A8I3P903 A0A8I3PA63 A0A8I3PC10 A0A8I3PDJ0 A0A8I3PFS2 A0A8I3PHA3 A0A8I3PK57 A0A8I3PQE6 A0A8I3PSF4 A0A8I3PSI0 A0A8I3PSI8 A0A8I3PSX7 A0A8I3PTU4 A0A8I3PVW4 A0A8I3PXL9 A0A8I3PZW5 A0A8I3Q2C8 A0A8I3Q4C7 A0A8I3Q5Y5 A0A8I3Q7H2 A0A8I3QA46 A0A8I3RR85 A0A8I3RSP2 A0A8I3RUA9 A0A8I3RZ95 A0A8I3S023 A0A8I3S0M3 A0A8I3S1I6 A0A8I3S2N1 A0A8I3S2X1 A0A8I3S449 A0A8I3S4X0 A0A8I3S565 A0A8I3S5V2 A0A8I3S7Q4 A0A8I3SB08 A0A8I3SB35 A0A8I3SCF9 A0A8I3SCQ9 P18067 P61162 Q4LAL9 Q5TJG5 Q5TJH0 Q9GL24	ACTR10 ACTR1A ACTR1B AP1B1 AP1M1 AP1M2 AP1S1 AP2A1 AP2A2 AP2B1 AP2M1 AP2S1 ARF1 CANX CAPZA2 CAPZA3 CAPZB CD74 CENPE CLTA CLTC CTRN1 CTSA CTSB CTSC CTSD CTSE CTSF CTSH CTSL CTSL1 CTSO CTSS DCTN1 DCTN3 DCTN4 DCTN5 DCTN6 DLA-DMA DLA-DMB DLA-DOA DLA-DQA1 DLA-DRA DNM1 DNM2 DNM3 DYNC1H1 DYNC1I1 DYNC1I2 DYNC1LI1 DYNC1LI2 DYNLL1 DYNLL2 HLA-DQB2 IFI30 KIF11 KIF18A KIF20A KIF22 KIF23 KIF26A KIF2B KIF2C KIF3A KIF3C KIF4A KIF5A KIF5B KIFAP3 KLC1 KLC3 KLC4 LAG3 LGMN LOC100856399 LOC119868747 LOC119876190 LOC612266 OSBPL1A PHLPP2 QTRT1 RAB7 RAB7A RACGAP1 RILP SEC13 SEC23A SEC24A SEC24B SEC24C SEC24D SEC31A SH3GL2 SPTBN2	Canis familiaris (dog)
Glycosphingolipid catabolism	Acid ceramidase Alpha-galactosidase Arylsulfatase A Arylsulfatase B Arylsulfatase F Arylsulfatase G Arylsulfatase K Arylsulfatase L Arylsulfatase family member H Arylsulfatase family member I Arylsulfatase family member J Beta-galactosidase Beta-galactosidase Beta-hexosaminidase Beta-hexosaminidase Carboxypeptidase Ectonucleotide pyrophosphatase/phosphodiesterase 7 Galactocerebrosidase Galactosidase beta 1 like Ganglioside GM2 activator Glucosylceramidase beta 3 (gene/pseudogene) Glucosylceramidase Mannose-6-phosphate receptor, cation dependent Neutral ceramidase Non-lysosomal glucosylceramidase Prosaposin Sialidase-1 Sphingomyelin phosphodiesterase Steroid sulfatase Sulfatase modifying factor 1 Sulfatase modifying factor 2 Uncharacterized protein exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A8I3MQM8 A0A8I3MQQ0 A0A8I3MQZ3 A0A8I3MY15 A0A8I3MZE8 A0A8I3N2H8 A0A8I3NC41 A0A8I3NF27 A0A8I3NH12 A0A8I3NJQ3 A0A8I3NK36 A0A8I3NK85 A0A8I3NN43 A0A8I3NQ68 A0A8I3NUS9 A0A8I3NZ71 A0A8I3PAY1 A0A8I3PBB8 A0A8I3PGV9 A0A8I3PHI8 A0A8I3PN86 A0A8I3PNW9 A0A8I3PP93 A0A8I3PPB0 A0A8I3PT92 A0A8I3Q0D0 A0A8I3Q139 A0A8I3Q2D2 A0A8I3Q545 A0A8I3Q695 A0A8I3RTW7 A0A8I3RW96 A0A8I3RZ95 A0A8I3S3Z3 Q32KH0 Q32KI4 Q9TRY9	ARSA ARSB ARSF ARSG ARSH ARSI ARSJ ARSK ARSL ASAH1 ASAH2 CTSA ENPP7 GALC GBA1 GBA2 GBA3 GLA GLB1 GLB1L GLB1L2 GM2A HEXA HEXB M6PR NEU1 NEU2 NEU3 NEU4 PSAP SMPD1 SMPD2 SMPD3 SMPD4 STS SUMF1 SUMF2 arsb	Canis familiaris (dog)	G09546QO G27025MB G58161NS
Vasopressin regulates renal water homeostasis via Aquaporins	Aquaporin-1 Aquaporin-2 Aquaporin-3 Aquaporin-4 Arginine vasopressin G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(s) subunit alpha Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Myosin VB Protein kinase cAMP-dependent type I regulatory subunit beta Protein kinase cAMP-dependent type II regulatory subunit beta RAB11 family interacting protein 2 Ras-related protein Rab-11A Vasopressin V2 receptor cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type I-alpha regulatory subunit cAMP-dependent protein kinase type II-alpha regulatory subunit cAMP-dependent protein kinase	A0A8I3ME07 A0A8I3MHA7 A0A8I3MM75 A0A8I3MNZ2 A0A8I3MYE3 A0A8I3N081 A0A8I3N0M1 A0A8I3NCW7 A0A8I3NP65 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NR61 A0A8I3NVA6 A0A8I3NZX3 A0A8I3P6A6 A0A8I3P7C5 A0A8I3PJF2 A0A8I3PRW9 A0A8I3PV05 A0A8I3PWA8 A0A8I3Q628 A0A8I3QJ88 A0A8I3QW96 A0A8I3RYN2 A0A8I3S5Y6 O97564 P62490 P62872 P63210 P79147 Q9N2J4	AQP1 AQP2 AQP3 AQP4 AVP AVPR2 GNAS GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 LOC119863873 MYO5B PRKACA PRKACB PRKAR1A PRKAR1B PRKAR2A PRKAR2B RAB11 RAB11A RAB11FIP2	Canis familiaris (dog)
Negative regulation of FGFR1 signaling	Anosmin 1 E3 ubiquitin-protein ligase CBL Fibroblast growth factor 23 Fibroblast growth factor 5 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Growth factor receptor bound protein 2 Klotho Mitogen-activated protein kinase Mitogen-activated protein kinase Multifunctional fusion protein Tyrosine-protein phosphatase non-receptor type Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0B4J199 A0A7U3JWB8 A0A8I3MBU4 A0A8I3MMN5 A0A8I3MP09 A0A8I3NFB9 A0A8I3NHF3 A0A8I3NKX5 A0A8I3NNZ2 A0A8I3NSU7 A0A8I3NTD6 A0A8I3NV07 A0A8I3NYK3 A0A8I3P4L9 A0A8I3PJY6 A0A8I3PMT9 A0A8I3PT69 A0A8I3PZP0 A0A8I3QYD0 A0A8I3RQD0 A0A8I3S906 A0A8I3SAY5 E2REX2 J9P0B3 J9P3I7 P63050 Q20FD0	ANOS1 CBL FGF1 FGF10 FGF17 FGF20 FGF22 FGF23 FGF3 FGF3A FGF4 FGF4B FGF5 FGF6 FGF7A FGF7B FGF8 FGF8B FGF9 FGFR1 FRS2 GRB2 KL MAPK1 MAPK3 PTPN11 RPS27A UBA52 UBB UBC UBCEP2	Canis familiaris (dog)
Ub-specific processing proteases	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ADRM1 26S proteasome ubiquitin receptor Androgen receptor Ataxin 7 Axin 2 Axin-1 Baculoviral IAP repeat containing 2 Baculoviral IAP repeat-containing protein 3 Beclin-1 Beta-2 adrenergic receptor Beta-arrestin-1 Beta-arrestin-2 Cell division cycle 20 Cellular tumor antigen p53 Centriolar coiled-coil protein 110 Claspin Cyclin-A1 Cyclin-A2 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator DNA polymerase E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Farnesylated proteins-converting enzyme 2 Forkhead box O4 GATA binding protein 3 Hepatocyte growth factor-regulated tyrosine kinase substrate Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2A Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Histone H2B Hypoxia-inducible factor 1-alpha Insulin degrading enzyme Interleukin-33 Kelch-like ECH-associated protein 1 M-phase inducer phosphatase Methionine adenosyltransferase 2 subunit beta Mitochondrial Rho GTPase Mitochondrial import receptor subunit TOM20 homolog Mitogen-activated protein kinase kinase kinase 7 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Myc proto-oncogene protein NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Protein Mdm4 RING-type E3 ubiquitin transferase RING-type E3 ubiquitin transferase RNA helicase Receptor interacting serine/threonine kinase 1 Ring finger protein 128 RuvB-like helicase SDS3 homolog, SIN3A corepressor complex component Signal transducing adaptor molecule 2 TATA-box binding protein associated factor 9b TGF-beta activated kinase 1 (MAP3K7) binding protein 1 TGF-beta receptor type-1 TNF receptor-associated factor 6 TNF receptor-associated factor Tankyrase 2 Transcription initiation factor TFIID subunit 10 Transcriptional adapter 3 Transcriptional adapter Transformation/transcription domain associated protein Translocase of outer mitochondrial membrane 70 USP domain-containing protein Ubiquitin B Ubiquitin carboxyl-terminal hydrolase 16 Ubiquitin carboxyl-terminal hydrolase 37 Ubiquitin carboxyl-terminal hydrolase 47 Ubiquitin carboxyl-terminal hydrolase 48 Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin carboxyl-terminal hydrolase CYLD Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin carboxyl-terminal hydrolase Ubiquitin specific peptidase 28 Ubiquitin specific peptidase 42 Ubiquitin thioesterase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Voltage-dependent anion-selective channel protein 1 Voltage-dependent anion-selective channel protein 2 Voltage-dependent anion-selective channel protein 3 WD repeat domain 20 WD repeat-containing protein 48 histone acetyltransferase peptidyl-tRNA hydrolase peptidylprolyl isomerase ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1 ubiquitinyl hydrolase 1	A0A7R7V602 A0A8I3MC37 A0A8I3MCW5 A0A8I3MDM0 A0A8I3MDQ5 A0A8I3MFT9 A0A8I3MJQ1 A0A8I3MKL2 A0A8I3MKL4 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MPG9 A0A8I3MQC7 A0A8I3MR89 A0A8I3MRP8 A0A8I3MSL4 A0A8I3MU16 A0A8I3MUE2 A0A8I3MWJ0 A0A8I3MWQ7 A0A8I3MZA5 A0A8I3N0P1 A0A8I3N165 A0A8I3N2P0 A0A8I3N371 A0A8I3N3A0 A0A8I3N3R0 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N683 A0A8I3N6Q2 A0A8I3N7L6 A0A8I3N7R6 A0A8I3N952 A0A8I3N9G3 A0A8I3NA81 A0A8I3NAP2 A0A8I3NAV8 A0A8I3NBQ5 A0A8I3NDB6 A0A8I3NEM9 A0A8I3NFB9 A0A8I3NGD3 A0A8I3NGL0 A0A8I3NGV0 A0A8I3NH42 A0A8I3NH60 A0A8I3NHL8 A0A8I3NLI9 A0A8I3NM89 A0A8I3NMN1 A0A8I3NN65 A0A8I3NNJ9 A0A8I3NP66 A0A8I3NP69 A0A8I3NPX1 A0A8I3NR70 A0A8I3NRK8 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NUT4 A0A8I3NV88 A0A8I3NW63 A0A8I3NW81 A0A8I3NWA6 A0A8I3NXK9 A0A8I3NY77 A0A8I3NYC7 A0A8I3NYE9 A0A8I3NYK2 A0A8I3NZ86 A0A8I3P0Y8 A0A8I3P135 A0A8I3P2V4 A0A8I3P616 A0A8I3P6B7 A0A8I3P6G1 A0A8I3P6J5 A0A8I3P6M2 A0A8I3P738 A0A8I3P7J9 A0A8I3P9V4 A0A8I3PB52 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCC0 A0A8I3PCE5 A0A8I3PCI4 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PE84 A0A8I3PF55 A0A8I3PF76 A0A8I3PFL3 A0A8I3PG60 A0A8I3PGG8 A0A8I3PHC7 A0A8I3PI05 A0A8I3PJL4 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PLL0 A0A8I3PMA2 A0A8I3PMH0 A0A8I3PNU1 A0A8I3PQ44 A0A8I3PQ52 A0A8I3PQD9 A0A8I3PU69 A0A8I3PVR3 A0A8I3PW10 A0A8I3PWL6 A0A8I3PWM3 A0A8I3PWW2 A0A8I3PX43 A0A8I3PY49 A0A8I3PYV8 A0A8I3PZ26 A0A8I3PZ42 A0A8I3PZ96 A0A8I3PZT2 A0A8I3Q0K8 A0A8I3Q3S2 A0A8I3Q4M1 A0A8I3Q5J1 A0A8I3Q610 A0A8I3Q7Y0 A0A8I3Q883 A0A8I3QA55 A0A8I3QBV9 A0A8I3QCQ3 A0A8I3QV78 A0A8I3QYD0 A0A8I3RP35 A0A8I3RRR7 A0A8I3RS56 A0A8I3RSX0 A0A8I3RT18 A0A8I3RT39 A0A8I3RV68 A0A8I3RVA5 A0A8I3RWV3 A0A8I3RWY9 A0A8I3RXL5 A0A8I3RXS6 A0A8I3RXV3 A0A8I3RZ76 A0A8I3RZD9 A0A8I3RZF7 A0A8I3RZF8 A0A8I3RZP6 A0A8I3RZQ8 A0A8I3S1Z6 A0A8I3S2L7 A0A8I3S2R9 A0A8I3S3G6 A0A8I3S4J6 A0A8I3S4R5 A0A8I3S6C6 A0A8I3S6H8 A0A8I3S6Q5 A0A8I3S789 A0A8I3S792 A0A8I3S794 A0A8I3S7M5 A0A8I3S9E1 A0A8I3S9T4 A0A8I3SCL5 A1E2V0 D2YYC0 E2RK09 E7FIY6 H9GWB1 J9P6S8 O97863 P56950 P60483 P63050 Q5U820 Q5W412 Q5W416	ABCC7 ADRB2 ADRM1 AR ARRB1 ARRB2 ATXN7 AXIN1 AXIN2 BECN1 BIRC2 BIRC3 CCNA1 CCNA2 CCP110 CDC20 CDC25A CDK16 CFTR CLSPN CYLD FKBP8 FOXO4 GATA3 H2AC1 H2AC13 H2AC14 H2AC16 H2AC19 H2AC21 H2AC25 H2AC4 H2AC6 H2BC10 H2BC15 H2BC2 H2BC21 H2BC26 H2BC3 HGS HIF1A IDE IFIH1 IKBKG IL33 KAT2A KEAP1 LOC100686569 LOC100687259 LOC100688437 LOC119867694 LOC119867696 LOC119867718 LOC119868881 LOC119869165 LOC119869175 LOC119869178 LOC119869187 LOC119869258 LOC119874734 LOC482940 LOC610717 MAP3K7 MAT2B MDM2 MDM4 MMAC1 MUL1 MYC Madh3 NFKBIA OTUB1 POLB PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 PTEN PTRH2 RCE1 RHOT1 RIPK1 RNF123 RNF128 RNF146 RPS27A RUVBL1 SIAH2 SMAD1 SMAD2 SMAD3 SMAD7 SMURF2 STAM2 SUDS3 TAB1 TADA2B TADA3 TAF10 TAF9B TGFBR1 TNKS TNKS2 TOMM20 TOMM70 TP53 TRAF2 TRAF6 TRRAP UBA52 UBB UBC UBCEP2 USP10 USP12 USP13 USP14 USP15 USP16 USP18 USP19 USP2 USP20 USP21 USP22 USP26 USP28 USP3 USP30 USP33 USP34 USP37 USP4 USP42 USP44 USP47 USP48 USP49 USP5 USP7 USP8 VDAC1 VDAC2 VDAC3 WDR20 WDR48 p53	Canis familiaris (dog)
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-3 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5F4C2B1 A0A8I3MVN6 A0A8I3N971 A0A8I3N9M7 A0A8I3NFE2 A0A8I3NUU1 A0A8I3NVH4 A0A8I3P519 A0A8I3PAP4 A0A8I3PBB4 A0A8I3PT69 A0A8I3PWC6 A0A8I3PWT3 A0A8I3Q525 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVV0 A0A8I3RX48 A0A8I3S3D9 A0A8I3S3N2 A0A8I3S4Z2 P48749 Q29416 Q95J76 Q9BDX4	CSF2 CSF2RA CSF2RB GAB2 GRB2 IL2 IL2RA IL2RB IL3 IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 LOC100856339 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN6 SHC1 SHIP2 SOS1	Canis familiaris (dog)
Initial triggering of complement	C4a anaphylatoxin Collectin subfamily member 10 Complement C1q B chain Complement C1q C chain Complement C1q subcomponent subunit A Complement C1s Complement C2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein complement subcomponent C1r	A0A8I3MAL2 A0A8I3MBH0 A0A8I3MKD7 A0A8I3MRI0 A0A8I3NH95 A0A8I3NLF4 A0A8I3NQQ5 A0A8I3NWR3 A0A8I3P1N5 A0A8I3P2M2 A0A8I3P2N6 A0A8I3P3T7 A0A8I3P4X4 A0A8I3P4Y5 A0A8I3P6V2 A0A8I3P941 A0A8I3PD67 A0A8I3PDU9 A0A8I3PG15 A0A8I3PJQ7 A0A8I3PL11 A0A8I3PQA6 A0A8I3PT15 A0A8I3PTN6 A0A8I3PUA5 A0A8I3PUL5 A0A8I3PUN5 A0A8I3PUP2 A0A8I3PUS1 A0A8I3PV91 A0A8I3PVB5 A0A8I3PVC4 A0A8I3PVG3 A0A8I3PWK4 A0A8I3PXN9 A0A8I3PXQ9 A0A8I3PYF1 A0A8I3Q5E2 A0A8I3QCV8 A0A8I3QD99 A0A8I3QE86 A0A8I3QF04 A0A8I3RST0 A0A8I3S0G9 A0A8I3S0K3 A0A8I3S6H5 A0A8I3S9C3 A0A8I3SAS3 A0A8I3SAS7	C1QA C1QB C1QC C1R C1S C2 COLEC10 FCN2 LOC481722 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
EPH-Ephrin signaling	EPH receptor A10 EPH receptor B6 EPH-related receptor tyrosine kinase ligand 7 Ephrin A2 Ephrin A3 Ephrin A4 Ephrin B3 Ephrin type-B receptor 3 Ephrin-A1 Ephrin-B2 Uncharacterized protein receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	A0A8I3MB23 A0A8I3MBN5 A0A8I3MD88 A0A8I3MVS4 A0A8I3N250 A0A8I3NEL5 A0A8I3NQ24 A0A8I3NR10 A0A8I3NS68 A0A8I3NYD1 A0A8I3PTE3 A0A8I3PZY2 A0A8I3Q5U0 A0A8I3QB00 A0A8I3RP21 A0A8I3RVX4 A0A8I3RZP3 A0A8I3S0G7 A0A8I3SCP8 B0LDS6	EFNA1 EFNA2 EFNA3 EFNA4 EFNA5 EFNB1 EFNB2 EFNB3 EPHA1 EPHA10 EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 EPHA8 EPHB2 EPHB3 EPHB4 EPHB6 efnB2	Canis familiaris (dog)
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 5 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 6B 26S proteasome regulatory subunit 7 26S proteasome regulatory subunit 8 ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ABC-type glutathione-S-conjugate transporter ATP binding cassette subfamily A member 4 ATP binding cassette subfamily A member 8 ATP binding cassette subfamily B member 1 ATP binding cassette subfamily B member 4 ATP binding cassette subfamily B member 5 ATP binding cassette subfamily B member 9 ATP binding cassette subfamily C member 10 ATP binding cassette subfamily C member 11 ATP binding cassette subfamily C member 4 ATP binding cassette subfamily C member 5 ATP binding cassette subfamily C member 9 ATP binding cassette subfamily F member 1 ATP-sensitive inward rectifier potassium channel 11 Cystic fibrosis transmembrane conductance regulator Cystic fibrosis transmembrane conductance regulator Derlin Derlin Derlin E3 ubiquitin-protein ligase RNF Endoplasmic reticulum lectin Endoplasmic reticulum lectin Erlin Erlin Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Proteasome 20S subunit alpha 3 Proteasome 26S subunit, ATPase 1 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 10 Proteasome 26S subunit, non-ATPase 12 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 3 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-8 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta SEL1L adaptor subunit of ERAD E3 ubiquitin ligase Transitional endoplasmic reticulum ATPase Ubiquitin B Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein protein-synthesizing GTPase	A0A8I3MFR7 A0A8I3MMN5 A0A8I3MNI0 A0A8I3MR89 A0A8I3MU16 A0A8I3MUE2 A0A8I3MV19 A0A8I3N0P1 A0A8I3N153 A0A8I3N165 A0A8I3N1B7 A0A8I3N1I8 A0A8I3N222 A0A8I3N2I4 A0A8I3N3S4 A0A8I3N5F1 A0A8I3N6K4 A0A8I3N6T3 A0A8I3N6X7 A0A8I3N7G8 A0A8I3N952 A0A8I3N9B0 A0A8I3N9G3 A0A8I3NB03 A0A8I3NFB9 A0A8I3NH42 A0A8I3NKE8 A0A8I3NN65 A0A8I3NND5 A0A8I3NNJ9 A0A8I3NNW7 A0A8I3NP66 A0A8I3NPX1 A0A8I3NUC6 A0A8I3NUK8 A0A8I3NV30 A0A8I3NVA4 A0A8I3NW81 A0A8I3NXK9 A0A8I3NXV6 A0A8I3NZK9 A0A8I3P6M2 A0A8I3PB85 A0A8I3PBB2 A0A8I3PCE5 A0A8I3PCT4 A0A8I3PDR8 A0A8I3PF55 A0A8I3PF76 A0A8I3PGC3 A0A8I3PJW0 A0A8I3PKH4 A0A8I3PM01 A0A8I3PMA2 A0A8I3PME6 A0A8I3PVZ3 A0A8I3PZT2 A0A8I3Q3Z7 A0A8I3Q7I5 A0A8I3QV78 A0A8I3QYD0 A0A8I3RRR7 A0A8I3RT39 A0A8I3RU74 A0A8I3RV68 A0A8I3RXV3 A0A8I3RZF7 A0A8I3RZP6 A0A8I3S0X8 A0A8I3S1Z6 A0A8I3S6C6 A0A8I3S6Q5 A0A8I3SCV5 B8K1W7 P63050 Q5U820 Q5W412 Q5W416 Q6UR05	ABCA4 ABCA8 ABCB1 ABCB4 ABCB5 ABCB9 ABCC1 ABCC10 ABCC11 ABCC2 ABCC3 ABCC4 ABCC5 ABCC6 ABCC7 ABCC9 ABCF1 Abcc4 CFTR DERL1 DERL2 DERL3 EIF2S1 EIF2S2 EIF2S3 ERLEC1 ERLIN1 ERLIN2 KCNJ11 LOC100686569 LOC100687259 LOC610717 MRP1 OS9 PSMA1 PSMA2 PSMA3 PSMA4 PSMA5 PSMA7 PSMA8 PSMB1 PSMB10 PSMB2 PSMB3 PSMB5 PSMB6 PSMB7 PSMB8 PSMB9 PSMC1 PSMC2 PSMC3 PSMC4 PSMC5 PSMD1 PSMD10 PSMD11 PSMD12 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME4 PSMF1 RNF5 RPS27A SEL1L UBA52 UBB UBC UBCEP2 VCP	Canis familiaris (dog)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	A0A8I3NGY1 Q867B7	HGF MET	Canis familiaris (dog)
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-2 5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Association with the SNF1 complex (ASC) domain-containing protein Autophagy and beclin 1 regulator 1 Autophagy protein 5 Autophagy related 13 Autophagy related 14 Autophagy related 16 like 1 Autophagy-related protein 101 Autophagy-related protein 9 Autophagy-related protein 9 Beclin-1 Charged multivesicular body protein 2B Charged multivesicular body protein 2a Charged multivesicular body protein 3 Charged multivesicular body protein 4A Charged multivesicular body protein 4B Charged multivesicular body protein 4C Charged multivesicular body protein 7 Cysteine protease ATG4D Cysteine protease Cysteine protease Cysteine protease Dynein light chain Dynein light chain GABA type A receptor associated protein like 2 Gamma-aminobutyric acid receptor-associated protein Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Microtubule associated protein 1 light chain 3 gamma Myotubularin related protein 14 Neutral amino acid transporter 9 Phosphatidylinositol 3-kinase catalytic subunit type 3 Protein kinase AMP-activated non-catalytic subunit gamma 2 Protein kinase AMP-activated non-catalytic subunit gamma 3 RB1 inducible coiled-coil 1 Ragulator complex protein LAMTOR1 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras homolog, mTORC1 binding Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory associated protein of MTOR complex 1 Serine/threonine-protein kinase mTOR Serine/threonine-protein kinase TSC complex subunit 1 TSC complex subunit 2 Target of rapamycin complex subunit LST8 UV radiation resistance associated Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein ATG12 Ubiquitin-like-conjugating enzyme ATG10 Ubiquitin-like-conjugating enzyme ATG3 Uncharacterized protein WD repeat domain phosphoinositide-interacting protein 2 WD repeat domain phosphoinositide-interacting protein 3 WD repeat domain phosphoinositide-interacting protein 4 WD repeat domain, phosphoinositide interacting 1 non-specific serine/threonine protein kinase protein-tyrosine-phosphatase	A0A8I3MF29 A0A8I3MJG3 A0A8I3MPV7 A0A8I3MS83 A0A8I3MTF8 A0A8I3MUN9 A0A8I3MWD3 A0A8I3MX71 A0A8I3N241 A0A8I3N3R3 A0A8I3N683 A0A8I3N7J8 A0A8I3N8Z8 A0A8I3N9T9 A0A8I3NBC3 A0A8I3NDI3 A0A8I3NFM6 A0A8I3NIS5 A0A8I3NIZ5 A0A8I3NME4 A0A8I3NR33 A0A8I3NRH7 A0A8I3NTI1 A0A8I3NTN6 A0A8I3P1L5 A0A8I3P1V6 A0A8I3P1X3 A0A8I3P2D4 A0A8I3P766 A0A8I3PBL8 A0A8I3PFE0 A0A8I3PFM5 A0A8I3PK33 A0A8I3PLN8 A0A8I3PM06 A0A8I3PP92 A0A8I3PPE0 A0A8I3PS98 A0A8I3PT36 A0A8I3PTC5 A0A8I3PWP1 A0A8I3PY75 A0A8I3PYA9 A0A8I3PZS6 A0A8I3Q041 A0A8I3Q098 A0A8I3Q0F1 A0A8I3Q4C7 A0A8I3QAP4 A0A8I3QCJ3 A0A8I3QFN1 A0A8I3QXU8 A0A8I3QZ96 A0A8I3RS87 A0A8I3RU83 A0A8I3RW45 A0A8I3RWY6 A0A8I3RXW5 A0A8I3S4R4 A0A8I3S4Z7 A0A8I3S6E7 A0A8I3SA74 E2RDP2	AMBRA1 ATG10 ATG101 ATG12 ATG13 ATG14 ATG16L1 ATG3 ATG4A ATG4B ATG4C ATG4D ATG5 ATG7 ATG9A ATG9B BECN1 CHMP2A CHMP2B CHMP3 CHMP4A CHMP4B CHMP4C CHMP7 DYNLL1 DYNLL2 GABARAP GABARAPL2 LAMTOR1 LAMTOR2 LAMTOR3 LAMTOR4 LAMTOR5 MAP1LC3C MLST8 MTMR14 MTMR3 MTOR PIK3C3 PIK3R4 PRKAA2 PRKAB1 PRKAB2 PRKAG1 PRKAG2 PRKAG3 RB1CC1 RHEB RPTOR RRAGA RRAGB RRAGC RRAGD SLC38A9 TSC1 TSC2 ULK1 UVRAG WDR45 WDR45B WIPI1 WIPI2	Canis familiaris (dog)
Recycling of bile acids and salts	ABC-type glutathione-S-conjugate transporter Albumin Bile acid-CoA Bile salt export pump Ileal sodium/bile acid cotransporter Nuclear receptor coactivator Nuclear receptor coactivator Nuclear receptor subfamily 1 group H member 4 Retinoic acid receptor RXR Solute carrier family 10 member 1 Solute carrier family 51 subunit alpha Solute carrier family 51 subunit beta Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member StAR related lipid transfer domain containing 5 long-chain-fatty-acid--CoA ligase	A0A8I3MAI7 A0A8I3MLS9 A0A8I3MY68 A0A8I3N1E1 A0A8I3N2S7 A0A8I3NIH7 A0A8I3NUI6 A0A8I3NXT1 A0A8I3PI53 A0A8I3PRC4 A0A8I3PYI4 A0A8I3Q2C1 A0A8I3RTD6 A0A8I3S0X8 B8K1W2 Q70HQ9	ABCC3 ALB Abcb11e BAAT BSEP NCOA1 NCOA2 NR1H4 RXRA SLC10A1 SLC10A2 SLC27A5 SLC51A SLC51B SLCO1A2 SLCO1B2 SLCO1B3 STARD5 slc10a2	Canis familiaris (dog)
Trafficking and processing of endosomal TLR	Canopy FGF signaling regulator 3 Cathepsin B Cathepsin S Endoplasmin Legumain Procathepsin L Toll like receptor 3 Toll like receptor 7 Toll like receptor 8 Toll-like receptor 9 Toll-like receptor 9 Unc-93 homolog B1, TLR signaling regulator	A0A8I3N2H5 A0A8I3NCE8 A0A8I3P6K4 A0A8I3P8U9 A0A8I3P903 A0A8I3PZY7 A0A8I3Q7B4 A0A8I3S0M3 A0A8I3SBE6 P41148 Q5I2M8 Q9GL24	CNPY3 CTSB CTSL CTSL1 CTSS GRP94 HSP90B1 HSPC4 LGMN TLR3 TLR7 TLR8 TLR9 TRA1 UNC93B1	Canis familiaris (dog)
Interferon gamma signaling	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Y-box-binding protein 1 Y-box-binding protein 1 Y-box-binding protein 1 calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A8I3MY73 A0A8I3NIS8 A0A8I3NMP2 A0A8I3NPS8 A0A8I3NU62 A0A8I3NVH4 A0A8I3NXV5 A0A8I3PF62 A0A8I3PSA1 A0A8I3PWC6 A0A8I3PZJ7 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 A0A8I3RWC7 P42161	CAMK2A CAMK2B CAMK2G IFNG IFNGR1 IFNGR2 JAK1 JAK2 LOC479011 MAPK1 MAPK3 PRKCD PTPN6 SOCS3 STAT1 YBX1	Canis familiaris (dog)
Hyaluronan biosynthesis and export	ATP binding cassette subfamily C member 5 Cell migration inducing hyaluronidase 1 Hyaluronan synthase 2 hyaluronan synthase hyaluronan synthase	A0A8I3MYT1 A0A8I3N9C7 A0A8I3ND97 A0A8I3PVZ3 A0A8I3RTT3	ABCC5 CEMIP HAS1 HAS2 HAS3	Canis familiaris (dog)	G35674CY
GP1b-IX-V activation signalling	14-3-3 protein zeta/delta RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase von Willebrand factor von Willebrand factor	A0A8I3PZA0 A0A8I3Q4Y8 A0A8I3SBF9 A0A8I3SCK0 Q28295	F8VWF RAF1 SRC VWF YWHAZ	Canis familiaris (dog)
Reactions specific to the complex N-glycan synthesis pathway	Alpha-(1,6)-fucosyltransferase Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase Alpha-L-fucosidase Alpha-mannosidase Alpha-mannosidase Carbohydrate sulfotransferase Fucosyltransferase	A0A8I3MHX5 A0A8I3MIH1 A0A8I3NLH2 A0A8I3NVI8 A0A8I3P218 A0A8I3RQC8 A0A8I3RTC2	CHST10 FUCA1 FUT5 FUT8 MAN2A1 MAN2A2 MGAT2	Canis familiaris (dog)	G70323CJ G82576YO
Integrin cell surface interactions	Basigin CD44 antigen Cadherin-1 Cadherin-1 Cartilage oligomeric matrix protein Collagen type IV alpha 1 chain Collagen type IV alpha 2 chain Collagen type IV alpha 3 chain Collagen type IV alpha 4 chain Collagen type IX alpha 1 chain Collagen type IX alpha 2 Collagen type IX alpha 3 chain Collagen type XIII alpha 1 chain Collagen type XVI alpha 1 chain Collagen type XVIII alpha 1 chain Fibrillin 1 Fibronectin Ig-like domain-containing protein Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 10 Integrin subunit alpha 11 Integrin subunit alpha 1 Integrin subunit alpha 2 Integrin subunit alpha 2b Integrin subunit alpha 3 Integrin subunit alpha 4 Integrin subunit alpha 5 Integrin subunit alpha 6 Integrin subunit alpha 8 Integrin subunit alpha 9 Integrin subunit alpha D Integrin subunit alpha E Integrin subunit alpha L Integrin subunit alpha M Integrin subunit alpha V Integrin-binding sialoprotein Intercellular adhesion molecule 1 Intercellular adhesion molecule 3 Intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) Intercellular adhesion molecule 5 Intercellular adhesion molecule N-terminal domain-containing protein Junctional adhesion molecule 3 Junctional adhesion molecule A Leukocyte surface antigen CD47 Lumican Mucosal vascular addressin cell adhesion molecule 1 Platelet and endothelial cell adhesion molecule 1 Secreted phosphoprotein 1 Tenascin C Thrombospondin 1 Vascular cell adhesion molecule 1 Vitronectin	A0A8I3MC22 A0A8I3MCY9 A0A8I3MJI6 A0A8I3MMP8 A0A8I3MQ67 A0A8I3N050 A0A8I3N567 A0A8I3NBM1 A0A8I3NFG9 A0A8I3NFV4 A0A8I3NG24 A0A8I3NL86 A0A8I3NM06 A0A8I3NNW2 A0A8I3NNX0 A0A8I3NS51 A0A8I3NUR7 A0A8I3NV00 A0A8I3NXU0 A0A8I3P0Q0 A0A8I3P1W2 A0A8I3P4K7 A0A8I3P4U9 A0A8I3P613 A0A8I3P684 A0A8I3P787 A0A8I3P7W0 A0A8I3PCF8 A0A8I3PCH7 A0A8I3PED8 A0A8I3PEP1 A0A8I3PHE2 A0A8I3PI20 A0A8I3PJI8 A0A8I3PMU9 A0A8I3PNK7 A0A8I3PPU8 A0A8I3PRY8 A0A8I3PUD7 A0A8I3PZA9 A0A8I3PZR7 A0A8I3Q3A8 A0A8I3Q413 A0A8I3Q8L7 A0A8I3QCJ7 A0A8I3RVE5 A0A8I3RVR5 A0A8I3RW71 A0A8I3RZG7 A0A8I3S0U4 A0A8I3S0V6 A0A8I3S131 A0A8I3S2B2 A0A8I3S700 A0A8I3S8N4 A0A8I3SBL1 E2DP67 F1PAA9	BSG CD44 CD47 CDH1 COL13A1 COL16A1 COL18A1 COL4A1 COL4A2 COL4A3 COL4A4 COL9A1 COL9A2 COL9A3 COMP F11R FBN1 FN1 IBSP ICAM1 ICAM2 ICAM3 ICAM4 ICAM5 ITGA1 ITGA10 ITGA11 ITGA2 ITGA2B ITGA3 ITGA4 ITGA5 ITGA6 ITGA8 ITGA9 ITGAD ITGAE ITGAL ITGAM ITGAV ITGB1 ITGB2 ITGB3 ITGB5 ITGB6 ITGB7 ITGB8 JAM3 LOC119867047 LUM MADCAM1 PECAM1 SEBOX SPP1 THBS1 TNC VCAM1	Canis familiaris (dog)
Sialic acid metabolism	Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase Beta-galactosidase Beta-galactoside alpha-2,6-sialyltransferase 2 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase Carboxypeptidase Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase Lactosylceramide alpha-2,3-sialyltransferase N-acetylneuraminate lyase N-acetylneuraminate synthase N-acylneuraminate cytidylyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST3 beta-galactoside alpha-2,3-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Sialidase-1 Solute carrier family 17 member 5 Solute carrier family 35 member A1 Type 2 lactosamine alpha-2,3-sialyltransferase Uncharacterized protein alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase beta-galactoside alpha-(2,6)-sialyltransferase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase	A0A8I3MKA0 A0A8I3MMF0 A0A8I3MQ19 A0A8I3MQZ3 A0A8I3MRB4 A0A8I3MRS4 A0A8I3MSL1 A0A8I3MWM9 A0A8I3MZA8 A0A8I3N2X1 A0A8I3N3C9 A0A8I3N9F9 A0A8I3NB27 A0A8I3NB67 A0A8I3NFK8 A0A8I3NHI8 A0A8I3NN43 A0A8I3NNC5 A0A8I3NR40 A0A8I3NVQ5 A0A8I3P0Y9 A0A8I3P9I7 A0A8I3PBB8 A0A8I3PGV9 A0A8I3Q6S3 A0A8I3RSF2 A0A8I3RV22 A0A8I3RWY3 A0A8I3RZ95 A0A8I3S0P4 A0A8I3S2B0 A0A8I3S5C7 Q9TRY9	CMAS CTSA GLB1 GNE NANP NANS NEU1 NEU2 NEU3 NEU4 NPL SLC17A5 SLC35A1 ST3GAL1 ST3GAL2 ST3GAL3 ST3GAL4 ST3GAL5 ST3GAL6 ST6GAL1 ST6GAL2 ST6GALNAC1 ST6GALNAC2 ST6GALNAC3 ST6GALNAC4 ST6GALNAC5 ST6GALNAC6 ST8SIA1 ST8SIA2 ST8SIA3 ST8SIA4 ST8SIA5 ST8SIA6	Canis familiaris (dog)
Glycosphingolipid biosynthesis	Beta-1,3-galactosyltransferase 4 Beta-1,4-N-acetyl-galactosaminyltransferase 1 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Ceramide kinase Hexosyltransferase L-Fucosyltransferase Lactosylceramide 4-alpha-galactosyltransferase Lactosylceramide alpha-2,3-sialyltransferase ST3 beta-galactoside alpha-2,3-sialyltransferase 3 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 UDP glycosyltransferase 8 beta-D-galactosyl-(1->3)-N-acetyl-beta-D-galactosaminide alpha-2,3-sialyltransferase ceramide glucosyltransferase	A0A8I3MCT3 A0A8I3MQ19 A0A8I3MWM9 A0A8I3MXG6 A0A8I3NA60 A0A8I3NB27 A0A8I3NFU6 A0A8I3NNC5 A0A8I3NPC1 A0A8I3NTR2 A0A8I3P0Y9 A0A8I3PUA8 A0A8I3PVY1 A0A8I3QHY8 A0A8I3RSF2 Q5TJE8	A4GALT B3GALNT1 B3GALT4 B4GALNT1 B4GALT5 B4GALT6 CERK FUT2 ST3GAL2 ST3GAL3 ST3GAL5 ST6GALNAC5 ST6GALNAC6 ST8SIA5 UGCG UGT8	Canis familiaris (dog)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	ALG14 UDP-N-acetylglucosaminyltransferase subunit Alpha-1,3-glucosyltransferase Alpha-1,3-glucosyltransferase Alpha-1,3/1,6-mannosyltransferase ALG2 Dol-P-Man Glycosyl transferase family 1 domain-containing protein Mannose-P-dolichol utilization defect 1 protein Mannosyltransferase Mannosyltransferase N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	A0A8I3MHT1 A0A8I3MVS8 A0A8I3MVX9 A0A8I3MWK6 A0A8I3N360 A0A8I3N4U3 A0A8I3NP95 A0A8I3NQR0 A0A8I3PHR6 A0A8I3PT73 A0A8I3Q0L6	ALG1 ALG12 ALG14 ALG2 ALG3 ALG6 ALG8 ALG9 DPAGT1 MPDU1	Canis familiaris (dog)
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
Extra-nuclear estrogen signaling	72 kDa type IV collagenase Caveolin-1 Caveolin-2 EGF-like domain-containing protein Epiregulin Estrogen receptor beta Estrogen receptor Focal adhesion kinase 1 G protein subunit alpha transducin 3 G protein subunit beta 2 G protein subunit beta 4 G protein subunit gamma 13 Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 Guanine nucleotide-binding protein G(T) subunit gamma-T1 Guanine nucleotide-binding protein G(i) subunit alpha-1 Guanine nucleotide-binding protein G(i) subunit alpha-2 Guanine nucleotide-binding protein G(i) subunit alpha-3 Guanine nucleotide-binding protein subunit beta-5 Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Guanine nucleotide-binding protein subunit gamma Matrix metallopeptidase 7 Matrix metalloproteinase-9 Palmitoyltransferase Palmitoyltransferase Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphoinositide-3-kinase regulatory subunit 2 Phosphoinositide-3-kinase regulatory subunit 3 Pro-epidermal growth factor Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase SHC-transforming protein 1 Sphingosine kinase 1 Sphingosine-1-phosphate receptor 3 Striatin Stromelysin-1 Tyrosine-protein kinase receptor Tyrosine-protein kinase Uncharacterized protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-4,5-bisphosphate 3-kinase type I protein arginine methyltransferase	A0A5F4C2B1 A0A8I3MAV6 A0A8I3MCQ8 A0A8I3ME07 A0A8I3MGS0 A0A8I3MHA7 A0A8I3MM75 A0A8I3MN99 A0A8I3MNZ2 A0A8I3MT80 A0A8I3MYE3 A0A8I3MZG1 A0A8I3N081 A0A8I3N0H9 A0A8I3N8T5 A0A8I3N971 A0A8I3NI71 A0A8I3NMY1 A0A8I3NPA7 A0A8I3NPM9 A0A8I3NUU1 A0A8I3P3M1 A0A8I3P478 A0A8I3P519 A0A8I3P7L3 A0A8I3PJF2 A0A8I3PQY2 A0A8I3PS34 A0A8I3PV05 A0A8I3Q314 A0A8I3Q5L9 A0A8I3RPS3 A0A8I3RQ77 A0A8I3RRT3 A0A8I3RSE4 A0A8I3RYJ5 A0A8I3RYN2 A0A8I3S0D0 A0A8I3S3N2 A0A8I3S583 A0A8I3SBF9 O46550 O97564 P33724 P38400 P62872 P63210 P79147 Q6Y4Q5	AREG BTC CAV CAV-2 CAV1 CAV2 EGF EGFR EPGN EREG ESR1 ESR2 GNAI1 GNAI2 GNAI3 GNAT3 GNB1 GNB2 GNB3 GNB4 GNB5 GNG11 GNG13 GNG2 GNG3 GNG4 GNG8 GNGT1 GNGT2 HBEGF IGF1R LOC100856339 LOC119863873 MMP2 MMP3 MMP7 MMP9 PIK3CA PIK3R1 PIK3R2 PRMT1 PTK2 S1PR3 SHC1 SPHK1 SRC STRN TGFA ZDHHC21 ZDHHC7	Canis familiaris (dog)

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