GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **268** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Signaling by ROBO receptors	Glypican-1 Slit guidance ligand 2 Slit guidance ligand 3	A0A8I3MRE2 A0A8I3NQC4 A0A8I3Q4U0	GPC1 SLIT2 SLIT3	Canis familiaris (dog)
Lectin pathway of complement activation	Collectin subfamily member 10 MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein	A0A8I3MRI0 A0A8I3NLF4 A0A8I3PG15 A0A8I3RST0	COLEC10 FCN2 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
Ficolins bind to repetitive carbohydrate structures on the target cell surface	MBL associated serine protease 1 MBL associated serine protease 2 Uncharacterized protein	A0A8I3MRI0 A0A8I3NLF4 A0A8I3PG15	FCN2 MASP1 MASP2	Canis familiaris (dog)	G49108TO G57321FI
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Hepsin Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type 2	A0A8I3MSC1 A0A8I3MW78 A0A8I3NGY1 A0A8I3NIY8 A0A8I3S6Z5 Q867B7	HGF HGFAC HPN MET SPINT1 SPINT2	Canis familiaris (dog)
Surfactant metabolism	ATP binding cassette subfamily A member 3 Adenosine receptor A2a Adhesion G protein-coupled receptor F5 Alpha-2A adrenergic receptor Alpha-2C adrenergic receptor C-type lectin domain-containing protein Coiled-coil domain containing 59 Colony stimulating factor 2 receptor subunit beta Cytoskeleton associated protein 4 Fibronectin type-III domain-containing protein GATA binding protein 6 LIM and cysteine rich domains 1 Napsin A aspartic peptidase P2Y purinoceptor 2 Palmitoyltransferase Pepsin A Pro-cathepsin H Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C SRCR domain-containing protein Sodium-dependent phosphate transport protein 2A Sodium-dependent phosphate transport protein 2B Transcription termination factor 1 Uncharacterized protein	A0A8I3MSD7 A0A8I3MZ62 A0A8I3NCW6 A0A8I3NFK5 A0A8I3NFY6 A0A8I3NHV8 A0A8I3NQ93 A0A8I3NR35 A0A8I3NUR4 A0A8I3NUT9 A0A8I3NWG1 A0A8I3NWJ3 A0A8I3NXR2 A0A8I3NZU4 A0A8I3P3J7 A0A8I3PBB4 A0A8I3PJM9 A0A8I3Q7S8 A0A8I3RTH9 A0A8I3RVV0 A0A8I3RW10 A0A8I3S9H9 P11617 Q9GMY6	ABCA3 ADGRF5 ADORA2A ADRA2A ADRA2C CCDC59 CKAP4 CSF2RA CSF2RB CTSH GATA6 LMCD1 LOC610540 NAPSA P2RY2 PGA PGNA RDC8 SFTPB SFTPC SFTPD SLC34A1 SLC34A2 TTF1 ZDHHC2	Canis familiaris (dog)
Scavenging by Class A Receptors	Apolipoprotein A-I Apolipoprotein B Apolipoprotein E Calreticulin Endoplasmin Macrophage receptor with collagenous structure Macrophage scavenger receptor 1 Secretoglobin family 3A member 2	A0A8I3MSG4 A0A8I3NM03 A0A8I3NVT5 A0A8I3PTI1 A0A8I3QIL7 A0A8I3S4D1 P18649 P41148	APOA1 APOB APOE CALR GRP94 HSP90B1 HSPC4 MARCO MSR1 SCGB3A2 TRA1	Canis familiaris (dog)
Sodium/Calcium exchangers	EF-hand domain-containing protein Sodium/calcium exchanger 1 Solute carrier family 24 member 2 Solute carrier family 24 member 3 Solute carrier family 24 member 4 Solute carrier family 24 member 5 Solute carrier family 8 member A2 Solute carrier family 8 member A3 Solute carrier family 8 member B1 Sorcin	A0A8I3MSQ7 A0A8I3MTJ5 A0A8I3NPM6 A0A8I3NX53 A0A8I3PDR2 A0A8I3PJY1 A0A8I3Q687 A0A8I3RTF4 A0A8I3RY81 P23685	CALM2 NCX1 SLC24A2 SLC24A3 SLC24A4 SLC24A5 SLC8A1 SLC8A2 SLC8A3 SLC8B1 SRI	Canis familiaris (dog)
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase Alpha-1,4 glucan phosphorylase EF-hand domain-containing protein Glycogen debranching enzyme Lysosomal alpha-glucosidase Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit Phosphorylase b kinase regulatory subunit glycogenin glucosyltransferase glycogenin glucosyltransferase phosphorylase kinase	A0A8I3MSQ7 A0A8I3N518 A0A8I3NJX4 A0A8I3P0C9 A0A8I3PK76 A0A8I3PPY6 A0A8I3PZN0 A0A8I3Q2T0 A0A8I3Q320 A0A8I3RSB1 A0A8I3S046	AGL CALM2 GAA GYG1 GYG2 PHKA1 PHKA2 PHKB PHKG2 PYGL PYGM	Canis familiaris (dog)	G58161NS
Histamine receptors	Histamine H1 receptor Histamine H2 receptor Histamine receptor H3 Histamine receptor H4	A0A8I3MSX9 A0A8I3NPW0 A0A8I3P226 P17124	HRH1 HRH2 HRH3 HRH4	Canis familiaris (dog)
GDP-fucose biosynthesis	Fucose kinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-mannose 4,6-dehydratase L-fucose mutarotase Solute carrier family 35 member C1	A0A8I3MTB3 A0A8I3NTS0 A0A8I3NVI9 A0A8I3PWT5 A0A8I3Q1E5 A0A8I3RTZ0	FCSK FPGT FUOM GFUS GMDS SLC35C1	Canis familiaris (dog)	G85196CF G96881BQ
Presynaptic depolarization and calcium channel opening	Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Calcium voltage-gated channel auxiliary subunit alpha2delta 3 Calcium voltage-gated channel auxiliary subunit beta 4 Calcium voltage-gated channel auxiliary subunit gamma 4 Voltage-dependent L-type calcium channel subunit beta-1 Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha Voltage-dependent R-type calcium channel subunit alpha Voltage-dependent calcium channel gamma-2 subunit	A0A8I3MU54 A0A8I3MZA1 A0A8I3N5F4 A0A8I3NMX5 A0A8I3NPX9 A0A8I3P8U8 A0A8I3PWX4 A0A8I3Q178 A0A8I3Q3U9 A0A8I3S464	CACNA1A CACNA1E CACNA2D2 CACNA2D3 CACNB1 CACNB2 CACNB3 CACNB4 CACNG2 CACNG4	Canis familiaris (dog)
Regulation of insulin secretion	ATP binding cassette subfamily C member 8 ATP-sensitive inward rectifier potassium channel 11 Calcium voltage-gated channel auxiliary subunit alpha2delta 2 Rap guanine nucleotide exchange factor 3 Rap guanine nucleotide exchange factor 4 Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 2 Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit alpha Voltage-dependent L-type calcium channel subunit beta-2 Voltage-dependent L-type calcium channel subunit beta-3 Voltage-dependent P/Q-type calcium channel subunit alpha Voltage-dependent R-type calcium channel subunit alpha cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase	A0A8I3MU54 A0A8I3N0M1 A0A8I3NPX9 A0A8I3NRK7 A0A8I3NVA4 A0A8I3P8U8 A0A8I3PMW4 A0A8I3PRW9 A0A8I3PW63 A0A8I3PZ28 A0A8I3Q2Z6 A0A8I3Q3U9 A0A8I3QY31 A0A8I3S0T4 A0A8I3S464	ABCC8 CACNA1A CACNA1C CACNA1D CACNA1E CACNA2D2 CACNB2 CACNB3 KCNJ11 PRKACA PRKACB RAPGEF3 RAPGEF4 SLC2A1 SLC2A2	Canis familiaris (dog)	G58161NS
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin-13 receptor subunit alpha-2 Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 5 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A8I3MUC6 A0A8I3NVH4 A0A8I3PDX4 A0A8I3PSA1 A0A8I3RS40 A0A8I3RV66 A0A8I3RXB9 A0A8I3S4Z2 A0A8I3S6B0 A0A8I3SBB2 O77762 P41148 Q95LF0 Q9N0W9	GRP94 HSP90B1 HSPC4 IL13 IL13RA1 IL13RA2 IL4 IL4R JAK1 JAK2 JAK3 SOCS5 STAT1 STAT3 STAT6 TRA1 TYK2	Canis familiaris (dog)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Cytochrome P450 family 8 subfamily B member 1 Prostacyclin synthase Prostaglandin E synthase 2 Prostaglandin E synthase Prostaglandin G/H synthase 1 Prostaglandin G/H synthase 2 Prostaglandin-H2 D-isomerase Thromboxane-A synthase carbonyl reductase (NADPH) glutathione transferase	A0A8I3MUQ9 A0A8I3PFY5 A0A8I3PJM8 A0A8I3PV18 A0A8I3Q8L4 A0SYQ0 B4YY03 E5RQH2 Q8HZR1 Q8SPQ9	CBR1 COX-2 COX1 CYP8B1 H-PGDS HPGDS PGES PTGDS PTGES PTGES2 PTGIS PTGS1 PTGS2 TBXAS1	Canis familiaris (dog)
Vitamin B5 (pantothenate) metabolism	4'-phosphopantetheine phosphatase Fatty acid synthase L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Mitochondrial coenzyme A transporter SLC25A42 PDZ domain-containing protein 11 Pantetheinase Solute carrier family 25 member 16 Solute carrier family 5 member 6	A0A8I3MUX5 A0A8I3MVX3 A0A8I3MY61 A0A8I3PCZ1 A0A8I3Q2U7 A0A8I3RQN4 A0A8I3S3J2 Q9TSX8	AASDHPPT FASN PANK4 PDZD11 SLC25A16 SLC25A42 SLC5A6 VNN1	Canis familiaris (dog)
Gastrin-CREB signalling pathway via PKC and MAPK	Gastrin/cholecystokinin type B receptor Gastrin Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase cAMP responsive element binding protein 1 non-specific serine/threonine protein kinase	A0A8I3MV42 A0A8I3NAU2 A0A8I3P721 A0A8I3PZN8 A0A8I3PZP0 A0A8I3RQD0 A0A8I3S2U7 P01353 P30552	CCKBR CREB1 GAS GAST MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3	Canis familiaris (dog)
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	A0A8I3MV46 A0A8I3Q5U6	ATAT1 HDAC6 MEC17	Canis familiaris (dog)
Interleukin-2 signaling	Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A8I3MVN6 A0A8I3N974 A0A8I3NAC6 A0A8I3NUU1 A0A8I3P3G0 A0A8I3RRY0 A0A8I3RS40 A0A8I3RVE7 A0A8I3RYS0 A0A8I3S4Z2 Q29416	IL2 IL2RA IL2RB JAK1 JAK3 LCK PTK2B SHC1 STAT5A STAT5B SYK	Canis familiaris (dog)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Toll-like receptor 9 Toll-like receptor 9 Uncharacterized protein non-specific serine/threonine protein kinase	A0A8I3MWD3 A0A8I3PJ50 A0A8I3PZW3 A0A8I3Q7B4 A0A8I3QFN1 Q5I2M8	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Canis familiaris (dog)
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Arachidonate 5-lipoxygenase Leukotriene C4 synthase Paraoxonase 3 Paraoxonase Paraoxonase	A0A8I3MWD6 A0A8I3PAM3 A0A8I3PDD9 A0A8I3PDF6 A0A8I3PDS2 A0A8I3SA30	ALOX5 ALOX5AP LTC4S PON1 PON2 PON3	Canis familiaris (dog)
CS/DS degradation	Alpha-L-iduronidase Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase Beta-hexosaminidase Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase Iduronate 2-sulfatase Neurocan Versican core protein	A0A8I3MXW0 A0A8I3MY15 A0A8I3N5J5 A0A8I3N8Z0 A0A8I3NUF9 A0A8I3P874 A0A8I3PDW3 A0A8I3PHY6 A0A8I3PI48 A0A8I3PNW9 Q01634 Q29393 Q32KH3 Q32KI4	ARSB BCAN BGN CSPG4 CSPG5 DCN DCN1C HEXA HEXB HYAL1 IDS IDUA NCAN VCAN arsb ids	Canis familiaris (dog)	G27025MB
Regulation of IFNG signaling	Fibronectin type-III domain-containing protein Interferon gamma Protein inhibitor of activated STAT 1 Signal transducer and activator of transcription Small ubiquitin-related modifier 1 Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A8I3MY73 A0A8I3MZ64 A0A8I3NU62 A0A8I3NVH4 A0A8I3NZS0 A0A8I3P2U6 A0A8I3PSA1 A0A8I3QCJ0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 PIAS1 PTPN2 SOCS3 STAT1 SUMO1	Canis familiaris (dog)
Interferon gamma signaling	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Protein kinase C delta type Signal transducer and activator of transcription Suppressor of cytokine signaling 3 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein Y-box-binding protein 1 Y-box-binding protein 1 Y-box-binding protein 1 calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase	A0A8I3MY73 A0A8I3NIS8 A0A8I3NMP2 A0A8I3NPS8 A0A8I3NU62 A0A8I3NVH4 A0A8I3NXV5 A0A8I3PF62 A0A8I3PSA1 A0A8I3PWC6 A0A8I3PZJ7 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 A0A8I3RWC7 P42161	CAMK2A CAMK2B CAMK2G IFNG IFNGR1 IFNGR2 JAK1 JAK2 LOC479011 MAPK1 MAPK3 PRKCD PTPN6 SOCS3 STAT1 YBX1	Canis familiaris (dog)
IFNG signaling activates MAPKs	Fibronectin type-III domain-containing protein Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase RAF proto-oncogene serine/threonine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein	A0A8I3MY73 A0A8I3NVH4 A0A8I3PZA0 A0A8I3PZP0 A0A8I3QCJ0 A0A8I3RQD0 A0A8I3RS40 P42161	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3 RAF1	Canis familiaris (dog)
O-linked glycosylation	Beta-1,4-glucuronyltransferase 1 Dolichyl-phosphate-mannose--protein mannosyltransferase Dolichyl-phosphate-mannose--protein mannosyltransferase Dystroglycan 1 Hexosyltransferase LARGE xylosyl- and glucuronyltransferase 1 LARGE xylosyl- and glucuronyltransferase 2 Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 Protein O-mannose kinase	A0A8I3MY95 A0A8I3N4J0 A0A8I3NBQ3 A0A8I3NME9 A0A8I3NRN3 A0A8I3P5F6 A0A8I3P946 A0A8I3QJ22 Q5NDE9 Q9TSZ6	AGO61 B3GALNT2 B4GAT1 DAG1 GTDC2 LARGE1 LARGE2 POMGNT1 POMGNT2 POMK POMT1 POMT2	Canis familiaris (dog)

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