GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **252** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism ▼	GlyTouCan ID
VxPx cargo-targeting to cilium	ADP-ribosylation factor Polycystin-2 Rab-3A-interacting protein Rab11 family-interacting protein 3 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A4FVK4 P35359 Q503R3 Q5U3E1 Q6DC20 Q6IVV8 Q7T005	arf4a pkd2 rab11a rab11fip3 rab3ip rab8 rab8a rho wu:fi15h09 zfo2 zgc:101030 zgc:103679 zgc:110270 zgc:162699 zgc:174360	Danio rerio (zebrafish)
Elevation of cytosolic Ca2+ levels	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B0R182 F1RCY2 Q7SZL9 Q7SZM0 Q7SZM1 Q7SZM2 Q9I8N8 U3N9R0	P2X.514 P2X3 bZ1P14.9 fb99b08 p2rx1 p2rx2 p2rx3 p2rx3a p2rx5 p2rx7 p2rx8 p2x3 p2x5 p2xr1 p2xr2 p2xr514 p2xr7 si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb99b08 zP2X3 zfP2X3	Danio rerio (zebrafish)
Termination of O-glycan biosynthesis	Alpha-2,6-sialyltransferase Alpha-2,6-sialyltransferase CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 4 isoform 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Protein HEG beta-galactoside alpha-2,3-sialyltransferase	A2RUW6 B8K0C9 F1R1A7 Q5NDG1 Q6R8J2 Q704S4	heg im:7151092 siat4 siat4c siat7D siat7c st3gal1l st3gal2l st3gal4 st3gal8 st6GalNAc III st6GalNAc-III st6galnac3 st6galnac4 wu:fb67c12 zgc:111788 zgc:153237 zgc:158162 zgc:73301	Danio rerio (zebrafish)
Adrenoceptors	Alpha-1B-adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor	A4QNV7 B3DHM6 Q5U3D9 Q90WY4 Q90WY5 Q90WY6	adra1bb adra2a adra2b adra2c adrb1 adrb2b zgc:103685 zgc:162188 zgc:194728 zgc:194731	Danio rerio (zebrafish)
Amine ligand-binding receptors	Si Trace amine associated receptor 69 Trace amine-associated receptor 10a Trace amine-associated receptor 12e Trace amine-associated receptor 12g Trace amine-associated receptor 13c Trace amine-associated receptor 13e Trace amine-associated receptor 14e Trace amine-associated receptor 14f Trace amine-associated receptor 15	B3DIB2 Q5QNN9 Q5QNP0 Q5QNP2 Q5QNP3 Q5QNP6 Q5QNP8 Q5QNQ3 Q5RG93 Q5RG95	si:ch211-119b12.1 si:ch211-119b12.3 si:dkey-7c18.1 si:dkey-7c18.17 si:dkey-7c18.19 si:dkey-7c18.20 si:dkey-7c18.21 si:dkey-7c18.7 si:dkey-7c18.9 ta66 taar10a taar12b taar12e taar12f taar12g taar13c taar13e taar14e taar14f taar15 taar66 taar69 taar72 zgc:194718	Danio rerio (zebrafish)
Adherens junctions interactions	Cadherin 11, osteoblast Cadherin 6 Cadherin-17 Cadherin-1 Cadherin-2 Cadherin-4 Cadherin-5 Cadherin-6 Cell adhesion molecule 1b isoform 1 Nectin 1b Nectin-3-like protein RNase 2 RNase 3 Ribonuclease-like 3	A1L1M6 A5HAK0 A5HAK1 A5HAK2 B0F6R1 B0JYH6 B3DGG4 Q2MLR9 Q58EG3 Q5WN09 Q68SP4 Q90275 Q90X63 Q90Z37	E-cad R-cadherin cadm1b cb903 cdh1 cdh10 cdh10a cdh11 cdh17 cdh2 cdh4 cdh5 cdh6 cdhvn fb65d02 nectin1b nectin3 pac pvrl1b pvrl3l rcad rnasel2 rnasel3 rnasel4 sc:d0664 si:ch211-139g14.6 vnc wu:fb65d02 zgc:103673 zgc:136316	Danio rerio (zebrafish)
RHO GTPases Activate Rhotekin and Rhophilins	Rho-related GTP-binding protein RhoA-C Rhophilin-2	Q6TNR1 Q7T2E8	rhoac rhpn2	Danio rerio (zebrafish)
FRS-mediated FGFR2 signaling	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor receptor substrate 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Putative fibroblast growth factor 1 Son of sevenless homolog	A2RRV5 B3DGE3 B3DHR9 E7F020 O57341 P48802 P79737 Q1XG76 Q2HXK8 Q38PL0 Q503B6 Q5MK87 Q5RKN6 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q8JG38 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf7 fgf8 fgf8a fgfr2 fj59e07 frs3 grb2 grb2a grb2b hrasb hrasl id:ibd5158 nras si:dkey-21e2.2 si:dkeyp-74c5.3 sos1 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fc89b01 wu:fd11d03 wu:fj59e07 zgc:103549 zgc:109774 zgc:110734 zgc:158274 zgc:194535 zgc:73077	Danio rerio (zebrafish)
Keratan sulfate biosynthesis	Beta-1,4-galactosyltransferase 5 Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-galactosyltransferase Beta-1,4-glucuronyltransferase 1 CMP-N-acetylneuraminate-beta-galactosamide- alpha-2,3-sialyltransferase 4 isoform 1 CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 Carbohydrate sulfotransferase 1 Fibromodulin Hexosyltransferase Hexosyltransferase Hexosyltransferase Keratocan Lumican Mimecan beta-galactoside alpha-2,3-sialyltransferase	A0A0R4ICJ7 A2RUW6 A8KB44 A8WHZ0 B8K0C9 C1KH59 E9QF32 F1R1A7 L7YAI7 Q3YL68 Q4V9E0 Q5BLC1 Q5RI43 Q6DBY9 Q6IQQ7 Q802Y5 Q8UWM4	B3GNT1 CH1073-177A15.1 Lum b3gnt1 b3gnt2b b3gnt3 b3gnt3.4 b3gnt7 b4galt1l b4galt2 b4galt4 b4galt5 b4galt6 b4gat1 cb543 chst1 fk70b01 fmoda im:6910494 im:7151092 kera lum ogn ogna si:ch211-103f16.4 si:ch211-261p7.4 siat4 siat4c ssp1 ssp5 st3gal1l st3gal2l st3gal4 st3gal8 wu:fa55h04 wu:fc39c01 wu:fk30b12 wu:fk70b01 zgc:101780 zgc:111788 zgc:113456 zgc:113545 zgc:113947 zgc:154116 zgc:158162 zgc:55730 zgc:86661	Danio rerio (zebrafish)
Acyl chain remodelling of PG	Acyl-CoA Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophosphatidylcholine acyltransferase 1 Phospholipase A2 cardiolipin synthase (CMP-forming) phospholipase A2	A3KNJ5 P50392 Q1LWG4 Q32PR6 Q4KMD5 Q6DHQ7 Q6NW82	aytl2 cpla2 crls1 fc21c12 fj66b10 lpcat1 lpgat1 pla2g10 pla2g12a pla2g3 pla2g4 pla2g4a si:dkey-30h14.2 wu:fc21c12 wu:fj66b10 zgc:112278 zgc:162119 zgc:85909	Danio rerio (zebrafish)
NGF processing	Furin (paired basic amino acid cleaving enzyme) a Nerve growth factor Proprotein convertase subtilisin/kexin type 5 preproprotein	F1QQ43 Q069L0 Q6YBR5	PCSK5 furin furina ngf ngfb pcsk5 pcsk5b si:dkey-281a24.5 zgc:165659	Danio rerio (zebrafish)
Glycosphingolipid catabolism	Cytosolic beta-glucosidase Neutral ceramidase Non-lysosomal glucosylceramidase Sphingomyelin phosphodiesterase 4 exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase exo-alpha-sialidase sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0JMM3 A7TUD6 B1B5D9 E7F5W0 F1QUD7 Q4V9A4 Q502A1 Q503Z4 Q5W7F1 Q6PFJ7	NSMase asah2 gba2 gba3 im:6912336 im:6912508 nSMase2 neu3.2 neu3.3 neu3.5 neu4 neuc.1 sb:eu489 si:ch73-316n6.2 si:dkey-11j5.6 smpd2 smpd2a smpd3 smpd4 zgc:100806 zgc:109998 zgc:153998	Danio rerio (zebrafish)	G58161NS
SHC-mediated cascade:FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Klotho Putative fibroblast growth factor 1 Son of sevenless homolog	A2RRV5 B3DGE3 F1RC43 O57341 P48802 P79737 Q1XG76 Q38PL0 Q503B6 Q5MK87 Q5RKN6 Q5TLE1 Q5TLE2 Q6PBT8 Q6PC73 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9	dob fb18e12 fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a fj59e07 grb2 grb2a grb2b hrasb hrasl id:ibd5158 kl nras si:dkey-21e2.2 si:dkeyp-74c5.3 sos1 wu:fb05c08 wu:fb18e12 wu:fb34e06 wu:fc89b01 wu:fd11d03 wu:fj59e07 zgc:103549 zgc:109774 zgc:110734 zgc:158274 zgc:194535 zgc:73077	Danio rerio (zebrafish)
FGFR2b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DHR9 P48802 Q1XG76 Q6PBT8 Q8AY90 Q8JG38	fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf22 fgf3 fgf7 fgfr2 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
Signaling by ALK	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma ALK and LTK ligand 1 ALK and LTK ligand 2b ALK tyrosine kinase receptor Midkine Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Pleiotrophin phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DHG9 E7F251 E7FAP8 F1QAD7 F8W2C9 F8W3R9 Q502U6 Q804J6 Q9DDG2	alk alkal1 alkal2b cb518 fb79b05 fj33b02 fj46f04 fj48a12 mdk mdk2 mdkb pik3ca pik3cb pik3r1 pik3r2 plcg1 plei2 ptn wu:fb65b05 wu:fb79b05 wu:fj33b02 wu:fj46f04 wu:fj48a12 wu:fj57a05 zHBNF zgc:111787	Danio rerio (zebrafish)
Enzymatic degradation of Dopamine by monoamine oxidase	Catechol O-methyltransferase A	F4ZGF2	comta	Danio rerio (zebrafish)
Nectin/Necl trans heterodimerization	Cell adhesion molecule 1b isoform 1 Nectin 1b Nectin-3-like protein	B0F6R1 B0JYH6 Q58EG3	cadm1b nectin1b nectin3 pvrl1b pvrl3l sc:d0664	Danio rerio (zebrafish)
Neurotransmitter receptors and postsynaptic signal transmission	Glycine receptor betaZ subunit (Fragment) Glycine receptor subunit alpha-2 Glycine receptor subunit alphaZ1	F1R8P4 O93430 Q9DES8	[b]Z fj42f03 glra1 glra2 glrb glrb1 glrba glyR beta wu:fj42f03	Danio rerio (zebrafish)
GP1b-IX-V activation signalling	Glycoprotein Ib platelet subunit beta LOC100004428 protein Nyctalopin Phosphatidylinositol 3-kinase regulatory subunit alpha Proto-oncogene tyrosine-protein kinase Src Tsukushi Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like isoform X1 von Willebrand factor	A4QNV9 B0S6V7 B8JLP1 E7F9Z1 Q00P20 Q1JPZ3 Q58A48 Q6P102	LOC100004428 VWF gp1bb hm:zehn0976 lrcc54 nyx pik3r1 si:ch1073-474e24.1 si:dkey-285c2.8 src tsk tsku vasn vasnb vwf wu:fb33b01 wu:fb65b05 ywhabl zgc:73065 zgc:77351	Danio rerio (zebrafish)
FGFR1c and Klotho ligand binding and activation	Fgf23 Fibroblast growth factor receptor 1-A Klotho	F1RC43 Q5MK87 Q90Z00	fgf23 fgfr1 fgfr1a kl	Danio rerio (zebrafish)
Hyaluronan biosynthesis and export	ATP-binding cassette sub-family C member 5	E1B2R7	abcc5 fj51h02 si:ch1073-183g13.2 wu:fj51h02	Danio rerio (zebrafish)	G35674CY
Degradation of the extracellular matrix	72 kDa type IV collagenase Brevican core protein Cadherin-1 Calpain 1, (mu/I) large subunit a Calpain small subunit 1 Calpain, small subunit 1 b Calpain-1 catalytic subunit-like isoform X1 Calpain-1 catalytic subunit Calpain-2 catalytic subunit Calpain-5 Calpain-7 Calpain-9 Cathepsin K Cathepsin L.1 Cathepsin L1-like precursor Decorin Im Im Matrix metalloproteinase 14 (Membrane-inserted) alpha Matrix metalloproteinase-9 Spp1 Stromelysin-2 precursor Uncharacterized protein LOC100136837 Uncharacterized protein LOC559822 Uncharacterized protein LOC567623 precursor Uncharacterized protein LOC678524 isoform X1 Uncharacterized protein LOC793035 precursor	A0JMG3 A4JYN2 A4QNV6 A7MBX1 A7MCR6 A8E588 A8KBT8 A8WFS5 A8WFS6 B4F6P1 B8A6G0 E7F0H3 E9QBE2 F1QW40 Q1LYC9 Q1RM69 Q568D6 Q5BLH5 Q6DG44 Q6DHT0 Q6IVB9 Q7SZM5 Q7T2J2 Q7T317 Q7ZUR1 Q803T1 Q90Z37	Capn1 DC E-cad MMPLf ZFMMP-9 bcan capn1 capn1a capn2a capn5a capn7 capn9 capns1 capns1a capns1b cb386 cb536 cb545 cb616 cdh1 ctsk ctsl ctsl.1 dcn decorin fa18a08 fb77d06 fi32a12 fj05a08 fj67g01 im:6910535 mmp14a mmp2 mmp30 mmp9 sb:cb386 si:ch211-202f3.4 si:dkey-239j18.2 si:dkey-269i1.3 si:dkey-46g23.4 spp1 wu:fa18a08 wu:fa95f03 wu:fa99h12 wu:fb02g06 wu:fb07b05 wu:fb08b05 wu:fb72b09 wu:fb77d06 wu:fb81g08 wu:fi32a12 wu:fi98c09 wu:fj05a08 wu:fj67g01 wu:fk89d01 wu:fl09e04 zgc:110367 zgc:110603 zgc:111821 zgc:113590 zgc:136396 zgc:136872 zgc:153446 zgc:162184 zgc:171446 zgc:171735 zgc:63788 zgc:64165 zgc:92089 zgc:92451	Danio rerio (zebrafish)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating Phosphoglucomutase-2 Ribokinase Ribulose-phosphate 3-epimerase Transaldolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	F1Q883 Q5U3H4 Q5XJS7 Q6IQD5 Q6NYE3 Q6P6Y0 Q6PBW9	RBKS Tal dera fi03d03 ik:tdsubc_2c8 pgd pgm2 rbks rpe rpia taldo1 wu:fa07h08 wu:fb93d11 wu:fc20b11 wu:fc32g02 wu:fi03d03 xx:tdsubc_2c8 zgc:101610 zgc:103524 zgc:111848 zgc:55585 zgc:66054 zgc:77113 zgc:86813	Danio rerio (zebrafish)	G31080DL
Transport of inorganic cations/anions and amino acids/oligopeptides	Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Amino acid transporter Cystinosin precursor Mitochondrial S-adenosylmethionine carrier protein Vesicular inhibitory amino acid transporter	A1L1T3 C5H4R2 D7RVR6 D7RVR8 D7RVS0 D7RVS5 Q4V9P0 Q503T0	EAAT3 EAAT5A SLC1A2a SLC1A7 ctns samc si:ch211-284b7.1 si:ch73-116b16.2 si:dkey-21n12.2 slc1a1 slc1a2a slc1a3b slc1a7 slc1a7a slc1a7b slc25a26 slc32a1 zgc:110194 zgc:158324 zgc:91959	Danio rerio (zebrafish)
RHO GTPases regulate CFTR trafficking	Cystic fibrosis transmembrane conductance regulator Golgi-associated PDZ and coiled-coil motif-containing Ras homolog family member Q	Q1LX78 Q6PHG0 Q7ZVI3	cftr fe38f01 gopc rhoq wu:fe38f01 wu:fi15a09 zgc:55997 zgc:56254 zgc:65853	Danio rerio (zebrafish)

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