GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **451 - 475** of **597** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Calcineurin activates NFAT	Calcineurin subunit B type 2 FI14603p NFAT nuclear factor, isoform B Peptidyl-prolyl cis-trans isomerase Fkbp12 Serine/threonine-protein phosphatase 2B catalytic subunit 1 Serine/threonine-protein phosphatase 2B catalytic subunit 2 Serine/threonine-protein phosphatase 2B catalytic subunit 3	A8JUV3 P48375 P48456 Q24214 Q27889 Q8IQ15 Q9VXF1	CBP1 CG10022 CG31960-RA CNA1 CNB2 CanA-14F CanA1 CanB2 CnnA14D Dmel\CG11172 Dmel\CG31960 EP1335 FK506-bp2 Fkbp12 MESR1 NF-AT5 NFAT NFAT5 Nfat Pp2B-14D PpD14 dNFAT	Drosophila melanogaster (fruit fly)
CLEC7A (Dectin-1) induces NFAT activation	Calcineurin subunit B type 2 FI14603p NFAT nuclear factor, isoform B Serine/threonine-protein phosphatase 2B catalytic subunit 1 Serine/threonine-protein phosphatase 2B catalytic subunit 2 Serine/threonine-protein phosphatase 2B catalytic subunit 3	A8JUV3 P48456 Q24214 Q27889 Q8IQ15 Q9VXF1	CBP1 CG10022 CG31960-RA CNA1 CNB2 CanA-14F CanA1 CanB2 CnnA14D Dmel\CG11172 Dmel\CG31960 EP1335 MESR1 NF-AT5 NFAT NFAT5 Nfat Pp2B-14D PpD14 dNFAT	Drosophila melanogaster (fruit fly)
Calmodulin induced events	FI14603p G protein-coupled receptor kinase 1 Protein kinase C, brain isozyme Protein kinase C, eye isozyme Putative protein kinase C delta type homolog	P05130 P13677 P32865 P83099 Q8IQ15	CBP1 CG10022 CG31960-RA Dmel\CG31960 Gprk-1 Gprk1 PKC1 PKC2 Pkc53E Pkcdelta inaC	Drosophila melanogaster (fruit fly)
RUNX3 regulates CDKN1A transcription	Maverick Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Protein decapentaplegic Protein lozenge Runt related A, isoform D Runt related B Segmentation protein Runt Zinc finger protein 2 p53 protein long form variant 1	M9PI08 O62609 O96660 P07713 P22814 P28167 Q8IMZ4 Q9V4E6 Q9VRA9 Q9W349	CG10873 CG1379 CG15453 CG15454 CG15455 CG31325 D-p53 DMP53 DSMAD2 DSmad2 Dm-P53 DmP53 Dmel\CG1775 Dmel\CG1901 Dmel\CG2262 Dmel\CG33336 Dmel\CG34145 Dmel\CG42267 Dmp53 Dp53 E(zen)3 MAV MED Mav Med Medea P53 RunxA RunxB SMAD2 SMAD4 SMOX Sad Smad Smad2 Smad4 SmoX Smox TGF-b anon-EST:Posey121 dSMAD2 dSmad2 dSmad4 dmP53 dmp53 dp53 dpp dsmad2 l(1)G0348 l(3)11m-254 l(3)12m-137 l(3)SG36 l(3)SG70 l(3)XIIm137 lz mav med medea p53 prac run sad smad2 smad4 smox ted tmp zfh-2 zfh2	Drosophila melanogaster (fruit fly)
Multifunctional anion exchangers	FI02016p FI02094p FI02923p FI18412p1 FI19428p1 GH10366p GH19970p IP12186p LD07878p LD47995p LP24461p Putative sodium-dependent multivitamin transporter Sodium-coupled monocarboxylate transporter 1 Sodium-coupled monocarboxylate transporter 2 Uncharacterized protein D3-100EF	P83740 P91659 Q7K155 Q8IN99 Q8IPY0 Q8SWV5 Q961Q9 Q9V9U1 Q9V9U2 Q9VBK1 Q9VGP3 Q9VLR8 Q9VQ85 Q9VVM6 Q9W3R0	CG10879 CG14539 CG2191-RA CG31090 CG31262-RA CG31668-PB CG32669 CG33124-PB CG42235-RD CG5845 CG6723-RA CG8451-PA CG8932 CG8934 CG8951 CG8957 CG8966 CG9657-RA D3-100EF Dmel\CG10444 Dmel\CG2187 Dmel\CG2191 Dmel\CG2196 Dmel\CG31262 Dmel\CG31668 Dmel\CG33124 Dmel\CG42235 Dmel\CG5485 Dmel\CG5687 Dmel\CG6723 Dmel\CG6928 Dmel\CG8451 Dmel\CG9657 Prestin Prestin-RA SLC5A11 SMVT Slc26a5 Smvt anon-100EF-D3 anon-EST:Posey42 bumpel cg9657 dPrestin dSLC5A10 dSLC5A12 dSLC5A13 dSLC5A14 dSLC5A2 dSLC5A3 dSLC5A5 dSLC5A6 dSLC5A7 dSLC5A8 dSLC5A9 dpres kumpel prestin rumpel salt salt-RB smvt	Drosophila melanogaster (fruit fly)
Thyroxine biosynthesis	Dual oxidase FI02016p FI02094p FI02923p FI19428p1 GH10366p GH19970p IP12186p Iodotyrosine deiodinase LD47995p LP24461p Peroxidasin Putative sodium-dependent multivitamin transporter Sodium-coupled monocarboxylate transporter 1 Sodium-coupled monocarboxylate transporter 2 Uncharacterized protein D3-100EF	E1JIB2 P83740 P91659 Q8IN99 Q8IPY0 Q8SWV5 Q961Q9 Q9V9U1 Q9V9U2 Q9VBK1 Q9VGP3 Q9VLR8 Q9VQ85 Q9VQH2 Q9VZZ4 Q9W3R0	CG10879 CG14539 CG2191-RA CG31090 CG31262-RA CG31668-PB CG32669 CG33124-PB CG42235-RD CG6723-RA CG8451-PA CG8932 CG8934 CG8951 CG8957 CG8966 CG9657-RA D3-100EF Dmel\CG10444 Dmel\CG2187 Dmel\CG2191 Dmel\CG2196 Dmel\CG31262 Dmel\CG31668 Dmel\CG33124 Dmel\CG42235 Dmel\CG5687 Dmel\CG6723 Dmel\CG8451 Dmel\CG9657 Duox Iyd Pxn SLC5A11 SMVT Smvt anon-100EF-D3 anon-EST:Posey42 bumpel cdt cg9657 dSLC5A10 dSLC5A12 dSLC5A13 dSLC5A14 dSLC5A2 dSLC5A3 dSLC5A5 dSLC5A6 dSLC5A7 dSLC5A8 dSLC5A9 kumpel rumpel salt salt-RB smvt	Drosophila melanogaster (fruit fly)
Phase 1 - inactivation of fast Na+ channels	Potassium voltage-gated channel protein Shal Uncharacterized protein, isoform A Uncharacterized protein, isoform E	P17971 Q8IR92 Q9VBL2	CG11105 CG12625 CG34144 CG42683 Dm_X:57642 Dmel\CG44422 Dmel\CG5890 SHAL2 Shal	Drosophila melanogaster (fruit fly)
Cytosolic sulfonation of small molecules	3'(2'),5'-bisphosphate nucleotidase 1 GH11818p MIP25022p1 Putative inositol monophosphatase 3 Sulfotransferase 3, isoform C Sulfotransferase 4, isoform A	A0A0B4KF40 A1Z9J8 Q9VAG9 Q9VHH0 Q9VYF2 Q9W1L8	CG11293 CG15743 CG16733-RA CG5431 Dmel\CG16733 Dmel\CG44167 Dmel\CG5428 Dmel\CG6704 Dmel\CG7789 St1 St2 St3 St4 dmST1 dmST2 dmST3 dmST4 st1 st2 st3 st4	Drosophila melanogaster (fruit fly)
Syndecan interactions	EG Integrin alpha-PS1 Integrin alpha-PS2 Integrin alpha-PS3 Integrin alpha-PS4 Integrin alpha-PS5 Integrin beta-PS Integrin beta-nu LD45181p Maverick Protein decapentaplegic Protein kinase C, brain isozyme Syndecan	O44386 O46099 P05130 P07713 P11584 P12080 P49415 Q24247 Q27591 Q9V4E6 Q9V7A4 Q9VFD1 Q9W1M8	CG11409-RB Dmel\CG11409 Dmel\CG1901 Dmel\CG6912 EG:8D8.2 ItgaPS4 ItgaPS5 ItgalphaPS4 ItgalphaPS5 Itgbetanu Itgbn MAV Mav PKC1 Pkc53E Sdc Syd TGF-b Vol alphaPS3 alphaPS4 alphaPS5 anon-WO0118547.571 anon-WO0140519.208 beta-nu betaInt-nu dpp if l(1)mys mav mew mys olfC scb	Drosophila melanogaster (fruit fly)
Apoptotic cleavage of cell adhesion proteins	Adherens junction protein p120 Armadillo segment polarity protein Caspase Polychaetoid, isoform O Putative neural-cadherin 2 RNA polymerase II elongation factor Ell	A0A0B4K6Y7 O01382 P18824 Q7PLI0 Q9VJB6 Q9VW51	CG11782 CG11962 CG12409 CG31349 CG9729 CG9731 CG9763 CT36877 CadN2 DZO-1 Dmel\CG17484 Dmel\CG43140 Dp120[ctn] Dp120ctn Drice Ell ICE P120 P120-catenin P120ctn Pch Pyd Pyd/ZO-1 Su(Tpl) Tamou ZO-1 ZO1 arm dP120ctn dp120ctn dzo-1 p120 p120[ctn] p120ctn pyd pyd(Z01) tam xvt	Drosophila melanogaster (fruit fly)
Regulation of Complement cascade	Corin, isoform B Notopleural, isoform A Peptidase S1 domain-containing protein Serine protease filzig Serine proteinase stubble Uncharacterized protein, isoform A trypsin trypsin trypsin	A1Z709 A1Z7M3 A1Z7M5 A1Z7M7 A8DY75 B7YZU2 Q05319 Q8IRR3 Q9W453	CG11824 CG6048-RA CG8181 Corin Dmel\CG13744 Dmel\CG2105 Dmel\CG32755 Dmel\CG34350 Dmel\CG6048 Dmel\CG8170 Dmel\CG8172 Np SP108 SP233 SP32 SP54 SP59 SP67 SP75 Sb Sb-sbd c-SP32 c-SP67 cSP32 cSP54 cSP59 cSP67 corin flz lint np	Drosophila melanogaster (fruit fly)
Voltage gated Potassium channels	Eag-like K[+] channel, isoform A GH12235p Hyperkinetic, isoform M KCNQ potassium channel, isoform F Potassium voltage-gated channel protein Shab Potassium voltage-gated channel protein Shaker Potassium voltage-gated channel protein Shal Potassium voltage-gated channel protein Shaw Potassium voltage-gated channel protein eag Shaw-like, isoform C	A1Z856 A1ZB14 A8DYR5 M9PHI0 P08510 P17970 P17971 P17972 Q02280 Q7JPB9	CG12215 CG12915 CG13111 CG17779 CG2287 CG32688 CG34319 CG4450 DKCNQ Derg Dm_X:51771 Dmel\CG3182 Dmel\CG33135 Dmel\CG34366 Dmel\CG43388 Dmel\CG5076 Elk Hk KCNQ KCNQ1 KQT KQT 1 Kv3 Kv3.2 SHAL2 SHAW2 Sei Sh Shab Shal Shaw Shawl dKCNQ dmELK eag elk erg hk kcnq1 lincRNA.975 mns sei seit shawl	Drosophila melanogaster (fruit fly)
GABA receptor activation	Gamma-aminobutyric acid receptor alpha-like Gamma-aminobutyric acid receptor subunit beta-like Gamma-aminobutyric acid receptor subunit beta IP12579p Rho guanine nucleotide exchange factor 3, isoform L	P25123 Q08832 Q24352 Q9VXL9 Q9W0S2	CG1225 CG13881 CG13882 CG13883 CG42377 CG42378 Dmel\CG43976 Dmel\CG8916 DrhoGEF3 Grd Lcch-14A Lcch3 Rdl RhoGEF RhoGEF3 rhoGEF3	Drosophila melanogaster (fruit fly)
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	GH23568p Integrin beta-PS Integrin linked kinase, isoform A Transforming growth factor beta-1-induced transcript 1 protein	P11584 Q2PDT4 Q9V400 Q9VWD0	CG12533 CG18061 CG18576 CT29478 CT40481 CT42454 DPaxillin DPxn DPxn37 DmILK Dmel\CG10504 Dmel\CG31794 Dmel\CG32528 Dpax DpaxA ILK Ilk PAX PDLP Pax Pxn dPax ilk l(1)mys l(3)78Ca mys olfC pAX parvin pax	Drosophila melanogaster (fruit fly)
N-glycan trimming and elongation in the cis-Golgi	Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase RE57134p	Q60GL7 Q9VMQ2	CG13431-RA Dmel\CG13431 Dmel\CG14015 GlcNAc-TI GlcNAcT1 MGAT1 Mgat1 Mgat1-RA dMGAT1 mgat1	Drosophila melanogaster (fruit fly)	G58161NS
Activation of the phototransduction cascade	Cyclic nucleotide-gated cation channel subunit A Cyclic nucleotide-gated ion channel subunit B, isoform A Uncharacterized protein, isoform E	A0A4P7VAE4 Q24278 Q9W2D5	CG13530 CG3536 Cncbeta Cng CngA CngB Dmel\CG17922 Dmel\CG42260 dCNCbeta dmCNG4 dmCNGB lincRNA.378	Drosophila melanogaster (fruit fly)
Regulation of pyruvate metabolism	AT14039p E3 ubiquitin-protein transferase MAEA FI21269p1 GH10162p GH17761p L-lactate dehydrogenase LD25271p Malic enzyme Polyubiquitin Pyruvate kinase Pyruvate kinase Pyruvate kinase Ran-binding proteins 9/10 homolog Serine/threonine-protein phosphatase Pgam5, mitochondrial Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein, isoform A Uncharacterized protein WD repeat-containing protein 26 homolog pyruvate kinase	A1Z9F8 E1JIZ4 O46084 O62619 P0CG69 P15357 Q0E9A5 Q4Z8K6 Q7K0L4 Q8MSB1 Q95028 Q9VD23 Q9VFG4 Q9VNZ9 Q9VQH0 Q9VVH0 Q9VWS1 Q9W2N5 Q9W418 R9PY16	CG13638 CG18282 CG7611 CR11700 CR32744 DmMK DmUb DmUbi-p5E Dmel\CG11249 Dmel\CG11700 Dmel\CG12229 Dmel\CG13334 Dmel\CG2964 Dmel\CG31357 Dmel\CG32744 Dmel\CG3295 Dmel\CG5889 Dmel\CG6617 Dmel\CG7069 Dmel\CG7362 Dmel\CG8811 ESTS:143G11T ESTS:199A6T Hou Imp-L3 ImpL3 Kaz Ldh MDH Mdh Men-b NEST:bs27e02 Pgam5 PyK RanBPM RpS27A Sou UB UB3-D UBI-F80 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin anon-EST:Posey180 anon-EST:Posey79 anon-sts41 muskelin muskelin-RB poly-ub	Drosophila melanogaster (fruit fly)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2a Probable 6-phosphogluconolactonase Probable transaldolase Ribokinase Ribulose-phosphate 3-epimerase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase transketolase transketolase	A1Z7P1 O77425 P12646 P41572 Q7K209 Q8MLS2 Q95RV5 Q9VHN7 Q9VVP4 Q9VZ64 Q9W1G0	CG1364 CG5103-RA CG9872 Dera Dmel\CG13369 Dmel\CG30410 Dmel\CG30499 Dmel\CG5103 Dmel\CG8036 Dmel\CG8073 Dmel\CG8525 Dredd EG:115C2.1 G6PD Pgd Pgls Pgm2a Pmm45A Rpe Rpi Tal Taldo Zw anon-WO0118547.344 rpi	Drosophila melanogaster (fruit fly)	G31080DL
Signaling by ROBO receptors	Dally-like, isoform A Protein sidekick Protein slit Roundabout 2, isoform B Toll-like receptor 6	M9PC46 O97394 P24014 Q9VUG1 Q9VUN0	CG14347 CG14348 CG17703 CG5031 CG5574 CT16138 CT17326 D-Robo2 D-gpcB D-robo2 DLP Dally-like Dlp Dly Dmel\CG32146 Dmel\CG5481 ROBO2 Robo Robo 2 Robo-2 Robo2 Robo2 (Lea) Tl-6 Toll-6 anon-EST:Liang-1.75 clone 1.75 dRobo-2 dlp dly fus4 lea robo robo-2 robo2 sdk sli	Drosophila melanogaster (fruit fly)
Regulation of expression of SLITs and ROBOs	Dystroglycan 1 GH17761p Polyubiquitin Protein slit Roundabout 2, isoform B Toll-like receptor 6 Ubiquitin carboxyl-terminal hydrolase Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eS31 fusion protein	A0A0C4DHF6 M9PC46 P0CG69 P15357 P24014 Q7JW61 Q9VUN0 Q9W418 R9PY16	CG14347 CG14348 CG18282 CG5574 CR11700 CR32744 CT17326 CT41273 D-Robo2 D-robo2 DG Dg DmDG DmUb DmUbi-p5E Dmel\CG11700 Dmel\CG18250 Dmel\CG32744 Dmel\CG5481 Dmel\CG8494 ESTS:143G11T ESTS:199A6T Q7JW61 ROBO2 Robo Robo 2 Robo-2 Robo2 Robo2 (Lea) RpS27A Tl-6 Toll-6 UB UB3-D UBI-F80 USP20 Ub Ubi Ubi-m Ubi-p5E Ubi-p5E5 Ubi-p63E Ubiq Ubiquitin Usp20 Usp20-33 Usp33 alpha-DG anon-EST:Liang-1.75 anon-sts41 atu clone 1.75 dRobo-2 dg dgn dys fus4 lea poly-ub robo robo-2 robo2 sli usp20-33	Drosophila melanogaster (fruit fly)
Regulation of cholesterol biosynthesis by SREBP (SREBF)	GTP-binding nuclear protein Ran Importin subunit beta LP12374p Membrane-bound transcription factor site-2 protease Serine endopeptidase Sterol regulatory element-binding protein cleavage-activating protein	A1Z6J2 O18388 Q7JZ56 Q9VP10 Q9VW37 Q9VZ23	CG14592 CG8356 Dmel\CG33131 Dmel\CG7169 Dmel\CG8522 Dmel\CG8988 Fs(2)Ket HLH106 HlH106 Ran Ran10A S1P S2P SCAP SKI-1/S1P SREBF1 SREBP SREBP1 Scap Scap_Dm Srebp anon-WO0118547.346 dS1P dS2P dSCAP dSREBP dScap dSrebp ds2p dscap dsrebp l(3)76BDw srebp	Drosophila melanogaster (fruit fly)
Collagen chain trimerization	Collagen alpha-1(IV) chain Multiplexin, isoform R	M9ND55 P08120	CG14822 CG33171 CG8645 CG8647 COL18A1 CT14872 Cg25C Col4a1 DCg1 Dmel\CG42543 Dmp Mp dmp mp multiplexin	Drosophila melanogaster (fruit fly)
Assembly of collagen fibrils and other multimeric structures	Multiplexin, isoform R	M9ND55	CG14822 CG33171 CG8645 CG8647 COL18A1 CT14872 Dmel\CG42543 Dmp Mp dmp mp multiplexin	Drosophila melanogaster (fruit fly)
Serotonin Neurotransmitter Release Cycle	Complexin GH10249p Liprin-alpha, isoform E Portabella Protein ROP RIM-binding protein, isoform F Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synapsin Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Unc-13, isoform E	A0A0B4JDC9 A0A0B4K6M2 H9XVP2 M9PCD4 P18489 P21521 P25228 P36975 Q07327 Q24546 Q24547 Q8IH57 Q8IPM8 Q9VCJ5 Q9VH76	CG14867 CG31302 CG5143 CG5152 CG6139 CG7301 CG7305 CG7321 DLiprin DLiprin-alpha DRBP DRIM DUNC-13 DVMAT DVMAT-A DVMAT-B Dliprin-alpha DmRIM Dmel\CG10251 Dmel\CG11199 Dmel\CG2999 Dmel\CG33528 Dmel\CG33547 Dmel\CG43073 Dmel\CG9474 Dunc-13 Dunc13 LIP LIP.1 LIP1 LPR Liprin Liprin-alpha Munc-13 Munc-13/UNC-13 RBP RIM Rab3 Rbp Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syn Syn-1 Syn-2 Syt1 Syx1A UNC-10/RIM UNC-13 UNC-13-B UNC13A UNC13B Unc-13 Unc13 Unc13A Unc13B VMAT Vmat Vmt cpx cs1 dUNC-13 dUnc-13 dVMAT dm-Rim drbp drunc13 dunc-13 l(2)SH0459 l(2)SH2 0459 l(4)ry16 lip-alpha liprin liprin-alpha lpr oos prt rbp rim rim-1 rim-bp syt syx-1A unc unc-13 vmat	Drosophila melanogaster (fruit fly)
Acetylcholine Neurotransmitter Release Cycle	Choline O-acetyltransferase Complexin High-affinity choline transporter 1 Liprin-alpha, isoform E Protein ROP RIM-binding protein, isoform F Rab3 interacting molecule, isoform F Ras-related protein Rab-3 Synaptobrevin Synaptosomal-associated protein 25 Synaptosomal-associated protein Synaptotagmin 1 Syntaxin-1A Unc-13, isoform E Vesicular acetylcholine transporter	A0A0B4JDC9 A0A0B4K6M2 H9XVP2 M9PCD4 O17444 P07668 P18489 P21521 P25228 P36975 Q07327 Q24547 Q8IPM8 Q9VE46 Q9VH76	CG14867 CG31302 CG5143 CG5152 CG7301 CG7305 CG7321 ChAT ChT Cha DLiprin DLiprin-alpha DRBP DRIM DUNC-13 Dliprin-alpha DmRIM Dmel\CG11199 Dmel\CG2999 Dmel\CG33547 Dmel\CG43073 Dmel\CG9474 Dunc-13 Dunc13 LIP LIP.1 LIP1 LPR Liprin Liprin-alpha Munc-13 Munc-13/UNC-13 RBP RIM Rab3 Rbp Rim Rop SNAP-24 SNAP-25b SNAP24 Snap24 Snap25 Snap25b Syb Syt1 Syx1A UNC-10/RIM UNC-13 UNC-13-B UNC13A UNC13B Unc-13 Unc13 Unc13A Unc13B VAChT cpx cs1 dUNC-13 dUnc-13 dm-Rim drbp drunc13 dunc-13 l(4)ry16 lip-alpha liprin liprin-alpha lpr oos rbp rim rim-1 rim-bp syt syx-1A unc unc-13	Drosophila melanogaster (fruit fly)

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