GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **1 - 25** of **250** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase, mitochondrial 3-oxoacyl-[acyl-carrier-protein] synthase homolog ADP,ATP carrier protein 1 ADP,ATP carrier protein 2 ADP,ATP carrier protein 3 ARS-binding factor 2, mitochondrial ATP synthase subunit 5, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial Aconitate hydratase, mitochondrial Aldehyde dehydrogenase 5, mitochondrial Arginase Citrate synthase, mitochondrial Cytochrome b-c1 complex subunit 8, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 4, mitochondrial Cytochrome c oxidase subunit 6, mitochondrial D-lactate dehydrogenase [cytochrome] 1, mitochondrial Ferrochelatase, mitochondrial Fumarate hydratase, mitochondrial Gamma-glutamyl phosphate reductase Heat shock protein 60, mitochondrial High mobility group protein 1 Hydroxymethylglutaryl-CoA synthase Import motor subunit, mitochondrial Intrastrand cross-link recognition protein Isoleucine--tRNA ligase, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL32m Lon protease homolog, mitochondrial Magnesium-activated aldehyde dehydrogenase, cytosolic Malate dehydrogenase, cytoplasmic Mitochondrial inner membrane m-AAA protease component YTA10 Mitochondrial inner membrane m-AAA protease component YTA12 Mitochondrial-processing peptidase subunit alpha Non-histone chromosomal protein 6A Non-histone protein 10 Potassium-activated aldehyde dehydrogenase, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Single-stranded DNA-binding protein RIM1, mitochondrial Small ribosomal subunit protein uS2m cAMP-dependent protein kinase type 2	P00401 P00427 P00812 P00830 P00854 P00890 P04037 P04710 P06245 P07251 P08417 P08525 P09457 P0CS90 P11632 P11914 P16622 P18238 P18239 P19414 P19882 P20967 P22133 P25348 P30902 P32445 P32473 P32891 P32902 P33417 P36775 P38077 P39525 P39925 P40047 P40341 P46367 P48526 P53163 P54115 P54839 P54885 Q02486 Q03435 Q03973 Q12233	AAC1 AAC2 AAC3 ABF2 ACO1 AFG3 ALD3 ALD4 ALD5 ALD6 ALD7 ALDH1 ALDH2 ALDH5 ATP1 ATP2 ATP20 ATP3 ATP3a ATP3b ATP5 ATP6 ATP7 CAR1 CEM1 CIT1 COX1 COX4 COX6 DLD DLD1 ENS1 ERG13 FUM1 GLU1 GLU3 HEM15 HIM1 HMGS HMO1 HMO2 HSM2 HSP60 ISM1 IXR1 KGD1 LON LYS6 MAS2 MDH2 MIF2 MIF4 MNP1 MRP4 MRP4A MRPL12 MRPL32 NHP10 NHP6A NHPA OGD1 OLI2 OLI4 ORD1 OSCP OXI3 PDB1 PET9 PHO1 PIM1 PKA2 PRO2 QCR8 RCA1 RIM1 SSC1 TPK2 YKR1 YTA10 YTA12	Saccharomyces cerevisiae (brewer's yeast)
Activation of the AP-1 family of transcription factors	ATF/CREB activator 1 ATF/CREB activator 2 CRE-binding bZIP protein SKO1 General control transcription factor GCN4 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P03069 P14681 P16892 P32485 P39970 P40535 P41808 Q00772 Q02100	AAS101 AAS3 ACA1 ACA2 ACR1 ARG9 CST6 DAC2 FUS3 GCN4 HOG1 KSS1 MPK1 SKO1 SLT2 SMK1 SSK3	Saccharomyces cerevisiae (brewer's yeast)
Oxidative Stress Induced Senescence	General control transcription factor GCN4 General transcriptional corepressor CYC8 Histone H2A.1 Histone H2A.2 Histone H2A.Z Histone H2B.1 Histone H2B.2 Histone H3-like centromeric protein CSE4 Histone H3 Histone H4 Mitogen-activated protein kinase HOG1 Serine/threonine-protein kinase STE11 Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial	P02293 P02294 P02309 P03069 P04911 P04912 P14922 P22217 P22803 P23561 P25372 P32485 P36012 P61830 Q12692	AAS101 AAS3 ARG9 CRT8 CSE4 CSL2 CYC8 GCN4 H2A1 H2A2 H2AZ H2B1 H2B2 HHF1 HHF2 HHT1 HHT2 HOG1 HTA1 HTA2 HTA3 HTB1 HTB2 HTZ1 SIN2 SPT11 SPT12 SSK3 SSN6 STE11 TRX1 TRX2 TRX3	Saccharomyces cerevisiae (brewer's yeast)
Recycling of eIF2:GDP	Eukaryotic translation initiation factor 2 subunit alpha Eukaryotic translation initiation factor 2 subunit beta Eukaryotic translation initiation factor 2 subunit gamma Translation initiation factor eIF2B subunit alpha Translation initiation factor eIF2B subunit beta Translation initiation factor eIF2B subunit delta Translation initiation factor eIF2B subunit epsilon Translation initiation factor eIF2B subunit gamma	P09032 P09064 P12754 P14741 P20459 P32481 P32501 P32502	AAS2 GCD1 GCD11 GCD2 GCD6 GCD7 GCN3 SUI2 SUI3 SUI4 TIF211 TIF212 TIF213 TIF221 TIF222 TIF223 TIF224 TIF225 TRA3	Saccharomyces cerevisiae (brewer's yeast)
Aspartate and asparagine metabolism	Asparagine synthetase [glutamine-hydrolyzing] 1 Asparagine synthetase [glutamine-hydrolyzing] 2 Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase, mitochondrial Mitochondrial aspartate-glutamate transporter AGC1 Putative zinc metalloprotease TRE2 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70	P23542 P47161 P49089 P49090 Q01802 Q08693 Q08919 Q12482	AAT1 AAT2 AGC1 ASN1 ASN2 ASP5 TRE1 TRE2 VPS70	Saccharomyces cerevisiae (brewer's yeast)
mRNA Capping	Cyclin CCL1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 General transcription and DNA repair factor IIH subunit SSL1 General transcription and DNA repair factor IIH subunit TFB1 General transcription and DNA repair factor IIH subunit TFB2 General transcription and DNA repair factor IIH subunit TFB4 General transcription and DNA repair factor IIH subunit TFB5 Nuclear cap-binding protein complex subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II transcription factor B subunit 3 Serine/threonine-protein kinase KIN28 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme subunit alpha	P04050 P06242 P06839 P08518 P16370 P20433 P20434 P20435 P20436 P22139 P27692 P27999 P32776 P32783 P34087 P34160 P37366 P38902 P40422 P41895 P41896 Q00578 Q01159 Q02939 Q03290 Q04673 Q08920 Q12004 Q3E7C1	ABD1 CBC1 CBC2 CBP20 CBP80 CCL1 CEG1 GCR3 KIN28 LOM3 MUD13 RAD25 RAD3 REM1 RIG2 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPO21 RPO22 RPO26 SAE1 SPT5 SSL1 SSL2 SSU71 STO1 SUA8 SUT1 TFB1 TFB2 TFB3 TFB4 TFB5 TFG1 TFG2 UVS112	Saccharomyces cerevisiae (brewer's yeast)
RNA Pol II CTD phosphorylation and interaction with CE	Cyclin CCL1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 General transcription and DNA repair factor IIH subunit SSL1 General transcription and DNA repair factor IIH subunit TFB1 General transcription and DNA repair factor IIH subunit TFB2 General transcription and DNA repair factor IIH subunit TFB4 General transcription and DNA repair factor IIH subunit TFB5 RNA polymerase II transcription factor B subunit 3 Serine/threonine-protein kinase KIN28 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta mRNA cap guanine-N7 methyltransferase mRNA-capping enzyme subunit alpha	P04050 P06242 P06839 P08518 P16370 P20433 P20434 P20435 P20436 P22139 P27692 P27999 P32776 P32783 P34087 P37366 P38902 P40422 P41895 P41896 Q00578 Q01159 Q02939 Q03290 Q04673 Q12004 Q3E7C1	ABD1 CCL1 CEG1 KIN28 LOM3 RAD25 RAD3 REM1 RIG2 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPO21 RPO22 RPO26 SPT5 SSL1 SSL2 SSU71 SUA8 TFB1 TFB2 TFB3 TFB4 TFB5 TFG1 TFG2 UVS112	Saccharomyces cerevisiae (brewer's yeast)
Neutrophil degranulation	1-acyl-sn-glycerol-3-phosphate acyltransferase 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 7 homolog 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit RPN5 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7 26S proteasome regulatory subunit RPN8 26S proteasome regulatory subunit RPN9 3-ketoacyl-CoA thiolase, peroxisomal AMP deaminase AP-1 complex subunit mu-1-I AP-2 complex subunit alpha ARS-binding factor 2, mitochondrial ATP-dependent 6-phosphofructokinase subunit alpha ATP-dependent 6-phosphofructokinase subunit beta ATP-dependent DNA helicase II subunit 1 ATP-dependent DNA helicase II subunit 2 ATP-dependent RNA helicase DED1 ATP-dependent molecular chaperone HSC82 ATP-dependent molecular chaperone HSP82 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Adenine phosphoribosyltransferase 1 Adenylyl cyclase-associated protein Arginase CTD kinase subunit alpha Calcium permeable stress-gated cation channel 1 Casein kinase II subunit beta' Cell division control protein 48 Centractin Coatomer subunit beta Cytidine deaminase DOCK-like protein 1 Damage response protein 1 Delta-aminolevulinic acid dehydratase DnaJ-like chaperone JEM1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 3 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST6 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1 Dynein heavy chain, cytoplasmic Dynein light chain 1, cytoplasmic E3 ubiquitin-protein ligase TOM1 ER-derived vesicles protein ERV29 ER-retained PMA1-suppressing protein 1 Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Elongation factor 1 alpha-like protein Elongation factor 1-alpha Elongation factor 2 Fatty aldehyde dehydrogenase HFD1 GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 GTP-binding protein YPT10 GTP-binding protein YPT52 GTP-binding protein YPT53 GTP-binding protein YPT6 GTPase-activating protein BEM3 GTPase-activating protein SAC7 Glucokinase-1 Glucose-6-phosphate isomerase Glycogen debranching enzyme Glycogen phosphorylase Glycogenin-1 Glycogenin-2 Heat shock protein SSA1 Heat shock protein SSA2 Heat shock protein SSA3 Heat shock protein SSA4 Hexokinase-1 Hexokinase-2 High mobility group protein 1 IME2-dependent-signaling protein Importin subunit beta-1 Inactive deaminase YBR284W Inactive deaminase YJL070C Increased sodium tolerance protein 2 Inosine-5'-monophosphate dehydrogenase 2 Inosine-5'-monophosphate dehydrogenase 3 Inosine-5'-monophosphate dehydrogenase 4 Intrastrand cross-link recognition protein Isocitrate dehydrogenase [NADP], mitochondrial Kinetochore-associated protein DSN1 Leucine aminopeptidase 2 Methyltransferase OMS1, mitochondrial Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 N-acetylglucosamine kinase NADH-cytochrome b5 reductase 1 Negative regulator of sporulation MDS3 Negative regulator of sporulation PMD1 Nicotinate phosphoribosyltransferase Non-histone chromosomal protein 6A Non-histone protein 10 Nucleoside diphosphate kinase Omega-amidase NIT3 Peptide transporter PTR2 Peroxiredoxin PRX1, mitochondrial Peroxiredoxin TSA1 Peroxiredoxin TSA2 Peroxisomal catalase A Phosphate metabolism protein 7 Phosphatidylglycerol/phosphatidylinositol transfer protein Phosphoglucomutase 1 Phosphoglucomutase 2 Phospholipase D1 Phospholipid-transporting ATPase DNF1 Phospholipid-transporting ATPase DRS2 Phospholipid-transporting ATPase accessory subunit CDC50 Phosphoribomutase Probable ferric reductase transmembrane component 8 Probable metabolite transport protein YBR241C Probable metalloprotease ARX1 Probable metalloreductase AIM14 Probable phospholipid-transporting ATPase DNF3 Proteasome subunit alpha type-2 Proteasome subunit alpha type-5 Proteasome subunit beta type-2 Protein AIM7 Protein HYM1 Protein ORM1 Protein ORM2 Protein kinase C-like 1 Protein transport protein SEC9 Purine nucleoside phosphorylase Putative glucokinase-2 Putative pyridoxal kinase BUD16 Pyruvate kinase 1 Pyruvate kinase 2 Rab GDP-dissociation inhibitor Ras GTPase-activating-like protein IQG1 Ras modification protein ERF4 Ras-related protein RSR1 Ras-related protein SEC4 Ribonuclease T2-like Ribosome-associated molecular chaperone SSB1 Ribosome-associated molecular chaperone SSB2 Serine/threonine-protein kinase BUR1 Signal recognition particle subunit SRP14 Sporulation-specific chitinase 2 Sporulation-specific mitogen-activated protein kinase SMK1 Sporulation-specific protein 20 Sporulation-specific protein 75 T-complex protein 1 subunit beta T-complex protein 1 subunit theta Trafficking protein particle complex subunit BET5 Transgelin Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase 2 Tyrosine-protein phosphatase 3 UBX domain-containing protein 2 Ubiquitin carboxyl-terminal hydrolase RPN11 Ubiquitin-binding protein CUE5 Ubiquitin-like modifier-activating enzyme ATG7 Uncharacterized protein RSN1 Uncharacterized protein YFR018C V-type proton ATPase subunit D V-type proton ATPase subunit a, Golgi isoform V-type proton ATPase subunit a, vacuolar isoform V-type proton ATPase subunit c Vacuolar import and degradation protein 28 Vacuolar protein sorting-associated protein 21 Vacuolar protein sorting-associated protein 73 Vacuolar protein sorting-associated protein IST1 Very long-chain fatty acid transport protein Vesicle-associated membrane protein-associated protein SCS2 Ypt/Rab-type GTPase YPT7 [PSI+] inducibility protein 3	P00549 P00812 P02829 P02994 P04806 P04807 P05373 P06634 P06738 P06780 P06781 P07560 P09435 P10591 P10592 P11484 P11632 P12709 P13856 P14681 P15108 P15202 P15274 P16861 P16862 P16892 P17121 P17555 P17709 P21954 P22202 P23293 P23639 P24583 P25043 P25044 P25353 P25515 P25656 P25694 P27796 P29461 P32324 P32379 P32381 P32464 P32485 P32563 P32565 P32610 P32634 P32660 P32769 P32807 P32873 P32901 P32939 P33297 P33299 P33333 P33401 P33417 P33767 P34227 P34760 P36010 P36017 P36018 P36019 P36022 P36126 P36143 P37012 P37296 P38065 P38142 P38146 P38150 P38225 P38250 P38626 P38696 P38697 P38764 P38862 P38930 P38985 P39076 P39524 P39683 P39958 P39988 P39997 P40016 P40048 P40075 P40150 P40357 P40358 P40361 P40518 P40547 P40557 P40568 P41808 P41810 P41912 P43588 P43599 P46958 P47011 P47079 P48439 P49435 P49954 P50094 P50095 P52489 P53094 P53109 P53142 P53224 P53337 P53843 Q00245 Q00246 Q00772 Q00776 Q02486 Q02647 Q02933 Q03262 Q03280 Q03435 Q03516 Q03630 Q03723 Q03862 Q03957 Q03973 Q04062 Q04120 Q04228 Q04359 Q04409 Q04437 Q04458 Q05788 Q06103 Q06142 Q06144 Q06204 Q06350 Q06409 Q06449 Q06538 Q06549 Q06625 Q06668 Q07798 Q08412 Q08723 Q08873 Q10740 Q12091 Q12156 Q12209 Q12250 Q12252 Q12280 Q12377 Q12408 Q12674 Q99260	ABF2 ACT2 ACT3 ACT5 AIM14 AIM7 AMD AMD1 APG7 APL3 APM1 APT1 ARC15 ARP1 ARP2 ARX1 ATG7 BEM3 BET5 BIN3 BUD1 BUD16 BUR1 CAP1 CAR1 CBR CBR1 CBR5 CCT2 CCT8 CDC19 CDC48 CDC50 CDD1 CIM5 CKB2 CLS7 CSC1 CTA1 CTK1 CTS2 CUE5 CUP5 CVT2 CYK1 DAC2 DAP1 DCK1 DED1 DHC1 DNF1 DNF3 DOA5 DRS2 DSN1 DYN1 DYN2 EFT1 EFT2 EMI2 EPS1 ERF4 ERV29 FAT1 FOX3 FRE8 FUS3 GA-5 GAL5 GDB1 GDI1 GEF2 GID5 GLG1 GLG2 GLK1 GPH1 HBS1 HDF1 HDF2 HEM2 HEX1 HFD1 HIM1 HKA HKB HMO1 HMO2 HOG1 HOR3 HPO2 HRD2 HSC82 HSM2 HSP82 HSP90 HSS7 HXK1 HXK2 HYM1 IDP1 IDS2 IMD2 IMD3 IMD4 IQG1 IST1 IST2 IXR1 JEM1 KAP95 KAR8 KSS1 LAP2 LSB2 MDS3 MPK1 MPR1 NAS1 NAS4 NAS5 NAS7 NDK1 NES24 NGK1 NHP10 NHP6A NHPA NIT3 NPC2 NPP1 NPP2 NPT1 OMS1 ORD1 ORM1 ORM2 OST3 OST6 PFK1 PFK2 PGI1 PGM1 PGM2 PGM3 PHM7 PIN3 PKC1 PLD1 PMD1 PNP1 POT1 POX3 PRE8 PRM15 PRS4 PRX1 PTP1 PTP2 PTP3 PTR2 PUP1 PUP2 PUR5 PYK1 PYK2 RHO1 RHO2 RHO3 RHO4 RNY1 RPD1 RPN1 RPN11 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPT1 RPT5 RSN1 RSR1 SAC7 SCP1 SCS2 SEC19 SEC26 SEC4 SEC9 SEL1 SEN3 SGV1 SHR5 SLC1 SLT2 SMK1 SPO14 SPO20 SPO75 SPP81 SRO6 SRP14 SRV2 SSA1 SSA2 SSA3 SSA4 SSB1 SSB2 SSK3 SSR2 STT1 STV1 SUN2 SWA3 SWA4 TCP2 TEF1 TEF2 TOM1 TPX1 TSA TSA1 TSA2 UBX2 VAM4 VID28 VMA3 VMA8 VPH1 VPS12 VPS21 VPS73 VPT12 WBP1 YAP54 YBR241C YBR284W YFR018C YG101 YG103 YJL070C YKU70 YKU80 YNK YNK1 YPT10 YPT21 YPT51 YPT52 YPT53 YPT6 YPT7 YTA1 YTA3 ZRG14	Saccharomyces cerevisiae (brewer's yeast)
Biotin transport and metabolism	Acetyl-CoA carboxylase, mitochondrial Acetyl-CoA carboxylase Biotin--protein ligase Pyruvate carboxylase 1	P11154 P32874 P48445 Q00955	ABP2 ACC1 ACC2 BPL1 FAS3 HFA1 MTR7 PYC1 PYV	Saccharomyces cerevisiae (brewer's yeast)
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Acyl-CoA desaturase 1 Very long-chain fatty acid transport protein	P21147 P35731 P38225 Q00955	ABP2 ACC1 FAS3 FAT1 MTR7 OAR1 OLE1	Saccharomyces cerevisiae (brewer's yeast)
RHOA GTPase cycle	Actin GTP-binding protein RHO1 GTPase-activating protein BEM3 GTPase-activating protein SAC7 Mitochondrial acidic protein MAM33 Phospholipase D1 Protein ECM25 Protein SLY1 Protein kinase C-like 1 Protein transport protein SEC9 Putative zinc metalloprotease TRE2 Ras GTPase-activating-like protein IQG1 Rho GDP-dissociation inhibitor Rho-GTPase-activating protein BAG7 Sporulation-specific protein 20 UBX domain-containing protein 2 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70	P06780 P17121 P22213 P24583 P32525 P32873 P36126 P40357 P40513 P47161 P60010 Q04228 Q04359 Q08693 Q08919 Q12128 Q12280 Q12434	ABY1 ACT1 BAG7 BEM3 CYK1 ECM25 END7 HPO2 HSS7 IQG1 MAM33 PKC1 PLD1 RDI1 RHO1 SAC7 SEC9 SEL1 SLY1 SPO14 SPO20 STT1 TRE1 TRE2 UBX2 VPS70	Saccharomyces cerevisiae (brewer's yeast)
RHOB GTPase cycle	Actin GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 Protein ECM25 Protein kinase C-like 1 Protein transport protein SEC9 Putative zinc metalloprotease TRE2 Ras GTPase-activating-like protein IQG1 Rho GDP-dissociation inhibitor Sporulation-specific protein 20 Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70	P06780 P06781 P24583 P32525 P40357 P47161 P60010 Q00245 Q00246 Q04359 Q08693 Q08919 Q12280 Q12434	ABY1 ACT1 CYK1 ECM25 END7 HPO2 HSS7 IQG1 PKC1 RDI1 RHO1 RHO2 RHO3 RHO4 SEC9 SPO20 STT1 TRE1 TRE2 VPS70	Saccharomyces cerevisiae (brewer's yeast)
HATs acetylate histones	ATF/CREB activator 1 ATF/CREB activator 2 CRE-binding bZIP protein SKO1 Histone H2B.1 Histone H2B.2 Histone H4 Histone acetyltransferase type B catalytic subunit Histone acetyltransferase type B subunit 2	P02293 P02294 P02309 P39970 P39984 P40535 Q02100 Q12341	ACA1 ACA2 ACR1 CST6 H2B1 H2B2 HAT1 HAT2 HHF1 HHF2 HTB1 HTB2 SKO1 SPT12	Saccharomyces cerevisiae (brewer's yeast)
Citric acid cycle (TCA cycle)	Aconitate hydratase, mitochondrial Citrate synthase, mitochondrial Fumarate hydratase, mitochondrial Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial Malate dehydrogenase, cytoplasmic Mitochondrial import inner membrane translocase subunit TIM18 Succinate dehydrogenase [ubiquinone] cytochrome b subunit, mitochondrial Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	P00890 P08417 P19414 P21801 P22133 P28241 P28834 P33421 P53312 P53598 Q00711 Q08749	ACO1 CIT1 CYB3 FUM1 GLU1 GLU3 IDH1 IDH2 LSC1 LSC2 LYS6 MDH2 SDH SDH1 SDH2 SDH3 SDHA SDHB TIM18	Saccharomyces cerevisiae (brewer's yeast)
Regulation of actin dynamics for phagocytic cup formation	Actin-like protein ARP9 Actin-related protein 2/3 complex subunit 1 Actin-related protein 2/3 complex subunit 2 Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 Serine/threonine-protein kinase STE20	P19073 P32381 P33204 P38328 P40518 P47117 P53731 Q03497 Q05123 Q05933	ACT2 ACT4 ARC15 ARC18 ARC19 ARC35 ARC40 ARP2 ARP3 ARP9 CDC42 SRO2 STE20 SWP59	Saccharomyces cerevisiae (brewer's yeast)
Ub-specific processing proteases	26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 homolog 26S proteasome regulatory subunit 8 homolog 26S proteasome regulatory subunit RPN12 26S proteasome regulatory subunit RPN1 26S proteasome regulatory subunit RPN2 26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit RPN5 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7 26S proteasome regulatory subunit RPN8 26S proteasome regulatory subunit RPN9 26S proteasome subunit RPT4 CAAX prenyl protease 2 Chromatin-remodeling complexes subunit NGG1 Histone H2A.1 Histone H2A.2 Histone H2B.1 Histone H2B.2 Histone acetyltransferase GCN5 M-phase inducer phosphatase Mediator of replication checkpoint protein 1 Polyubiquitin Probable 26S proteasome regulatory subunit p27 Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1 Probable proteasome subunit alpha type-7 Proteasome activator BLM10 Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit beta type-1 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-7 SWIRM domain-containing protein FUN19 SWIRM domain-containing protein YOR338W Small ribosomal subunit protein eS1A Small ribosomal subunit protein eS1B Sorting nexin-3 Transcription initiation factor TFIID subunit 10 Transcription initiation factor TFIID subunit 9 Transcription-associated protein 1 Transcriptional adapter 2 Transcriptional regulatory protein DEP1 Transcriptional regulatory protein SDS3 Ubiquitin carboxyl-terminal hydrolase 10 Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase 2 Ubiquitin carboxyl-terminal hydrolase 3 Ubiquitin carboxyl-terminal hydrolase 6 Ubiquitin carboxyl-terminal hydrolase 8 Ubiquitin carboxyl-terminal hydrolase RPN11 Y' element ATP-dependent helicase YEL077C Y' element ATP-dependent helicase YIL177C Y' element ATP-dependent helicase YJL225C Y' element ATP-dependent helicase YLL066C Y' element ATP-dependent helicase YLL067C Y' element ATP-dependent helicase YML133C Y' element ATP-dependent helicase YPR204W Y' element ATP-dependent helicase protein 1 copy 1 Y' element ATP-dependent helicase protein 1 copy 2 Y' element ATP-dependent helicase protein 1 copy 3 Y' element ATP-dependent helicase protein 1 copy 4 Y' element ATP-dependent helicase protein 1 copy 5 Y' element ATP-dependent helicase protein 1 copy 6 Y' element ATP-dependent helicase protein 1 copy 7 Y' element ATP-dependent helicase protein 1 copy 8	O13559 P02293 P02294 P04911 P04912 P0CG63 P0CX14 P0CX15 P0CX20 P0CX21 P0CX22 P21242 P21243 P22141 P23248 P23638 P23639 P23748 P25043 P25451 P25588 P28003 P30656 P30657 P31385 P32379 P32494 P32496 P32565 P33297 P33298 P33299 P33442 P38624 P38764 P38811 P40016 P40105 P40302 P40303 P40327 P40434 P40505 P40555 P40889 P43583 P43588 P43593 P50101 P50102 P53549 P53819 P53874 P53916 Q01476 Q01477 Q01939 Q02336 Q03099 Q03330 Q03530 Q04062 Q05027 Q06103 Q07888 Q08723 Q08826 Q08995 Q12030 Q12250 Q12377 Q3E7X8 Q99208 Q99326	ADA2 ADA3 ADA4 BLM10 BLM3 CIM3 CIM5 CRL13 CRL3 DEP1 DOA3 DOA5 DOT4 FUN19 FUN54 GCN5 GRD19 H2A1 H2A2 H2B1 H2B2 HRD2 HTA1 HTA2 HTB1 HTB2 MIH1 MPR1 MRC1 NAS1 NAS2 NAS4 NAS5 NAS7 NGG1 NIN1 PCS1 PLC1 PLC2 PRC1 PRC2 PRE1 PRE10 PRE2 PRE3 PRE4 PRE5 PRE6 PRE8 PRE9 PRG1 PRS1 PRS2 PRS4 PRS5 PUP1 PUP2 PUP3 RCE1 RPD1 RPN1 RPN11 RPN12 RPN2 RPN3 RPN5 RPN6 RPN7 RPN8 RPN9 RPS10A RPS10B RPS1A RPS1B RPT1 RPT2 RPT3 RPT4 RPT5 RPT6 SCD2 SCL1 SDS3 SEN3 SNX3 SPT11 SPT12 SUG1 SUG2 SUN2 SWI7 SWI9 TAF10 TAF17 TAF23 TAF25 TAF9 TBPY TBY1 TEP1 TRA1 UBI4 UBP10 UBP15 UBP2 UBP3 UBP6 UBP8 YEL077C YHS4 YIL177C YJL225C YLL066C YLL067C YML133C YNT1 YOR338W YPR204W YRF1-1 YRF1-2 YRF1-3 YRF1-4 YRF1-5 YRF1-6 YRF1-7 YRF1-8 YTA1 YTA2 YTA3 YTA5	Saccharomyces cerevisiae (brewer's yeast)
Estrogen-dependent gene expression	ATP-dependent RNA helicase DBP2 CTD kinase subunit alpha CTD kinase subunit beta DNA damage-responsive transcriptional repressor RPH1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 Fork head protein homolog 1 Forkhead transcription factor HCM1 Histone H2A.1 Histone H2A.2 Histone H2A.Z Histone H2B.1 Histone H2B.2 Histone H3-like centromeric protein CSE4 Histone H3 Histone H4 Histone acetyltransferase ESA1 Histone acetyltransferase GCN5 Histone deacetylase RPD3 Nitrogen regulatory protein DAL80 Nitrogen regulatory protein GLN3 Polyamine oxidase FMS1 Protein BUR2 Protein GZF3 Protein arginine N-methyltransferase 1 TATA-box-binding protein Transcription initiation factor IIA large subunit Transcription initiation factor IIA subunit 2 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta Transcriptional activator/repressor GIS1 Transcriptional regulator NRG1 Transcriptional regulatory protein GAT1	P02293 P02294 P02309 P04050 P04911 P04912 P08518 P13393 P16370 P18494 P20433 P20434 P20435 P20436 P22139 P24783 P25364 P26343 P27999 P32561 P32773 P32774 P34087 P36012 P38074 P38902 P39956 P40422 P40466 P41895 P41896 P42944 P43574 P46962 P50264 P61830 Q03125 Q03330 Q03833 Q03957 Q05949 Q08649 Q12692	ADA4 BTF1 BUR2 CSE4 CSL2 CST4 CTK1 CTK2 DAL80 DBP2 ESA1 FKH1 FMS1 GAT1 GCN5 GIS1 GLN3 GZF3 H2A1 H2A2 H2AZ H2B1 H2B2 HCM1 HHF1 HHF2 HHT1 HHT2 HMT1 HTA1 HTA2 HTA3 HTB1 HTB2 HTZ1 MOF6 MSS1 NRG1 ODP1 REC3 RMT1 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPD3 RPH1 RPO21 RPO22 RPO26 SDI2 SDS6 SIN2 SPT11 SPT12 SPT15 SSU71 SUA8 SWI9 TBP1 TFG1 TFG2 TOA1 TOA2 UGA43	Saccharomyces cerevisiae (brewer's yeast)
Interconversion of nucleotide di- and triphosphates	Adenylate kinase isoenzyme 6 homolog FAP7 Adenylate kinase CTP synthase 1 CTP synthase 2 Deoxyuridine 5'-triphosphate nucleotidohydrolase GTP Glutathione reductase Guanylate kinase Nucleoside diphosphate kinase Ribonucleoside-diphosphate reductase large chain 1 Ribonucleoside-diphosphate reductase small chain 1 Ribonucleoside-diphosphate reductase small chain 2 Thioredoxin-1 Thioredoxin-2 Thioredoxin-3, mitochondrial Thymidylate kinase Thymidylate synthase Uridylate kinase	P00572 P06785 P07170 P09938 P15454 P15700 P21524 P22217 P22803 P25372 P26364 P28274 P33317 P36010 P38627 P41921 P49723 Q12055	ADK1 ADK2 AKY AKY1 AKY2 AKY3 CDC21 CDC8 CRT3 CRT6 CRT7 CRT9 DUT1 FAP7 GLR1 GUK1 NDK1 PAK3 RIR1 RNR1 RNR2 RNR4 SDS12 SOC8 TMP1 TRX1 TRX2 TRX3 URA6 URA7 URA8 YNK YNK1	Saccharomyces cerevisiae (brewer's yeast)
Factors involved in megakaryocyte development and platelet production	Bud site selection protein RAX1 Cell division control protein 42 DOCK-like protein 1 F-actin-capping protein subunit alpha F-actin-capping protein subunit beta GTP-binding protein YPT10 GTP-binding protein YPT52 GTP Mitofusin FZO1 Vacuolar protein sorting-associated protein 45 Vacuolar segregation protein PEP7 cAMP-dependent protein kinase regulatory subunit cAMP-dependent protein kinase type 1 cAMP-dependent protein kinase type 2 cAMP-dependent protein kinase type 3	P05986 P06244 P06245 P07278 P13517 P19073 P26364 P28495 P32609 P36018 P38146 P38297 P38932 Q06409 Q08760	ADK2 AKY3 BCY1 CAP1 CAP2 CDC42 DCK1 FZO1 PAK3 PEP7 PKA1 PKA2 PKA3 RAX1 REG1 SRA1 SRA3 SRO2 STT10 TPK1 TPK2 TPK3 VAC1 VPL21 VPL28 VPS19 VPS45 VPT19 YKR1 YPT10 YPT52	Saccharomyces cerevisiae (brewer's yeast)
APAP ADME	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Cys-Gly metallodipeptidase DUG1 Glutathione hydrolase proenzyme Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 Probable ATP-dependent permease	P0CE68 P14772 P25371 P32386 P38735 P39109 P43616 P53049 Q05902	ADP1 BAT1 BPT1 CIS2 DUG1 ECM38 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Heme degradation	ABC transporter ATP-binding protein/permease VMR1 ABC transporter NFT1 ATP-dependent bile acid permease Bile pigment transporter 1 Metal resistance protein YCF1 Oligomycin resistance ATP-dependent permease YOR1 Probable ATP-dependent permease	P0CE68 P14772 P25371 P32386 P38735 P39109 P53049	ADP1 BAT1 BPT1 NFT1 VMR1 YBT1 YCF1 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Iron uptake and transport	Cell division control protein 53 F-box protein YDR306C F-box protein YLR352W NEDD8-like protein RUB1 Probable ATP-dependent permease Suppressor of kinetochore protein 1 Uncharacterized membrane protein YJL163C	P25371 P46996 P52286 Q03919 Q06479 Q06640 Q12018	ADP1 CBF3D CDC53 RUB1 SKP1 YDR306C YJL163C YLR352W	Saccharomyces cerevisiae (brewer's yeast)
Heme biosynthesis	5-aminolevulinate synthase, mitochondrial Delta-aminolevulinic acid dehydratase Ferrochelatase, mitochondrial Heme A synthase COX15 Oxygen-dependent coproporphyrinogen-III oxidase Porphobilinogen deaminase Probable ATP-dependent permease Protoheme IX farnesyltransferase, mitochondrial Protoporphyrinogen oxidase Uroporphyrinogen decarboxylase Uroporphyrinogen-III synthase	P05373 P06174 P09950 P11353 P16622 P21592 P25371 P28789 P32347 P40012 P40086	ADP1 COX10 COX15 CYD1 HEM1 HEM12 HEM13 HEM14 HEM15 HEM2 HEM3 HEM4 HEM6 ORF1 POP3	Saccharomyces cerevisiae (brewer's yeast)
Sphingolipid de novo biosynthesis	3-ketodihydrosphingosine reductase TSC10 Ceramide synthase LAC1 Ceramide synthase LAG1 Ceramide very long chain fatty acid hydroxylase SCS7 Cytochrome b5 Mitochondrial import inner membrane translocase subunit TIM54 Oligomycin resistance ATP-dependent permease YOR1 Probable ATP-dependent permease Sphingoid long chain base kinase 4 Sphingoid long chain base kinase 5	P25371 P28496 P38342 P38703 P40312 P47045 P53049 Q03529 Q06147 Q12246	ADP1 CYB5 DGT1 FAH1 LAC1 LAG1 LCB4 LCB5 SCS7 TIM54 TSC10 YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
ABC transporters in lipid homeostasis	Peroxisomal biogenesis factor 3 Peroxisomal long-chain fatty acid import protein 1 Peroxisomal long-chain fatty acid import protein 2 Peroxisomal membrane protein import receptor PEX19 Probable ATP-dependent permease Uncharacterized ABC transporter ATP-binding protein/permease YOL075C	P25371 P28795 P34230 P41909 Q07418 Q08234	ADP1 PAL1 PAS12 PAS3 PAT1 PAT2 PEX19 PEX3 PXA1 PXA2 SSH2 YOL075C	Saccharomyces cerevisiae (brewer's yeast)

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