GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **251 - 275** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
Interleukin-3, Interleukin-5 and GM-CSF signaling	14-3-3 protein zeta/delta Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein Granulocyte-macrophage colony-stimulating factor Interleukin 5 receptor subunit alpha Interleukin-5 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Proto-oncogene vav SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0A0MY60 A0A286ZQX2 A0A287BFJ1 A0A480LMF4 A0A5G2QEJ3 A0A5K1UB41 A0A5K1UPW2 A0A5K1V5Y3 A0A8X9AEI7 E7CR01 F1S916 F1SEA4 F1SFL9 F1SKR9 F2Z558 O19064 Q29118 Q9MYM5	CSF2 CSF2RA CSF2RB IL5 IL5RA JAK2 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PTPN11 SHC1 STAT5A STAT5B TEC VAV1 YWHAZ stat5B	Sus scrofa (pig)
Signaling by CSF3 (G-CSF)	Colony stimulating factor 3 receptor GRB2 associated binding protein 2 Granulocyte colony-stimulating factor Granulocyte colony-stimulating factor Growth factor receptor bound protein 2 SHC-transforming protein 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type small monomeric GTPase	A0A286ZLI2 A0A287B630 A0A287BSA9 A0A480LMF4 A0A5G2QVW3 A0A5G2QXL6 A0A5K1V5Y3 B6E241 F1RT53 F1S3L9 I3LCQ9 O02837 O19064	CSF3 CSF3R GAB2 GRB2 HCK JAK1 JAK2 KRAS LYN PTPN11 SHC1 TYK2	Sus scrofa (pig)
Inactivation of CSF3 (G-CSF) signaling	Colony stimulating factor 3 receptor Granulocyte colony-stimulating factor Granulocyte colony-stimulating factor Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A287BSA9 A0A5G2QVW3 A0A5G2QXL6 F1RT53 F1S3L9 O02837 O19064	CSF3 CSF3R HCK JAK1 JAK2 LYN TYK2	Sus scrofa (pig)
Transport of bile salts and organic acids, metal ions and amine compounds	Choline transporter-like protein 2 Choline transporter-like protein 4 Choline transporter-like protein Choline transporter-like protein Multidrug and toxin extrusion protein Multidrug and toxin extrusion protein Solute carrier family 10 member 6 Solute carrier family 14 member 2 Urea transporter 1	A0A287ARM7 A0A287BPI3 A0A8W4FLB7 A5PF08 F1RQG4 F1S542 F1S584 F1SDC6 I3LIG7	CTL2 CTL4 SLC10A6 SLC14A1 SLC14A2 SLC44A1 SLC44A2 SLC44A3 SLC44A4 SLC47A1 SLC47A2 TPPT1	Sus scrofa (pig)
RUNX1 regulates transcription of genes involved in differentiation of keratinocytes	Cathepsin K Cathepsin L	F1S4J6 Q9GLE3	CTSK CTSL	Sus scrofa (pig)
Prolactin receptor signaling	Cullin 1 E3 ubiquitin-protein ligase RBX1 Growth hormone 1 Prolactin receptor Prolactin S-phase kinase-associated protein 1 SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2	A0A286ZMM6 A0A287ARU4 A0A287B501 A0A5S6I4D7 F1RFI0 O19064 P01238 P01248 Q6JTA8	CUL1 GH1 JAK2 PRL PRLR RBX1 SH2B1 SKP1	Sus scrofa (pig)
Vitamin C (ascorbate) metabolism	Cytochrome b5 Glutathione S-transferase omega-1 NADH-cytochrome b5 reductase Solute carrier family 2, facilitated glucose transporter member 1 Solute carrier family 2, facilitated glucose transporter member 3 Solute carrier family 23 member 1	A0A5G2QPB6 I3LCS3 O62787 P00172 P20303 Q9N1F5	CYB5 CYB5A CYB5R3 GLUT1 GLUT3 GSTO1 SLC23A1 SLC2A1 SLC2A3	Sus scrofa (pig)
Melanin biosynthesis	5,6-dihydroxyindole-2-carboxylic acid oxidase L-dopachrome tautomerase OCA2 melanosomal transmembrane protein Solute carrier family 45 member 2 Tyrosinase	A0A8W4FBC9 F1SP14 F6Q7U8 Q4R1H1 Q4R1H3	DCT OCA2 SLC45A2 TYR TYRP1 TYRP2	Sus scrofa (pig)
Non-integrin membrane-ECM interactions	Tyrosine-protein kinase receptor receptor protein-tyrosine kinase	A0A287A959 A0A287BGA1	DDR1 DDR2	Sus scrofa (pig)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco Transcription factor AP-2-alpha	A0A287B9K7 A0A5G2QII0	DEK TFAP2A	Sus scrofa (pig)
Pentose phosphate pathway	6-phosphogluconate dehydrogenase, decarboxylating 6-phosphogluconolactonase Glucose-6-phosphate 1-dehydrogenase Phosphoglucomutase 2 Ribokinase Ribulose-phosphate 3-epimerase Sedoheptulokinase Transaldolase Transketolase deoxyribose-phosphate aldolase ribose-5-phosphate isomerase	A0A286ZQY9 A0A286ZS31 A0A287A7K4 A0A287BSL9 A0A5G2QMT1 A0A5G2QR34 A8U4R4 F1RLI9 F1S4K7 F1STC1 Q29593	DERA G6PD PGD PGLS PGM2 RBKS RPE RPIA SHPK TALDO1 TKT tkt	Sus scrofa (pig)	G31080DL
Keratinization	4Fe-4S ferredoxin-type domain-containing protein Desmocollin 1 Desmocollin 2 Desmocollin 3 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein 4 Desmoglein-1 Desmoplakin IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein IF rod domain-containing protein Junction plakoglobin Junction plakoglobin Keratin 12 Keratin 15 Keratin 18 Keratin 23 Keratin 24 Keratin 26 Keratin 28 Keratin 2 Keratin 31 Keratin 32 Keratin 35 Keratin 36 Keratin 39 Keratin 3 Keratin 40 Keratin 4 Keratin 71 Keratin 72 Keratin 73 Keratin 74 Keratin 75 Keratin 77 Keratin 78 Keratin 79 Keratin 80 Keratin 82 Keratin 84 Keratin 85 Keratin associated protein 8-1 Keratin, type I cytoskeletal 10 Keratin, type I cytoskeletal 17 Keratin, type I cytoskeletal 19 Keratin, type I cytoskeletal 20 Keratin, type I cytoskeletal 25 Keratin, type I cytoskeletal 27 Keratin, type II cytoskeletal 1 Keratin, type II cytoskeletal 5 Keratin, type II cytoskeletal 7 Keratin-associated protein 12-1-like Keratin-associated protein 12-1-like Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Keratin-associated protein Plakophilin 1 Plakophilin 2 Plakophilin 3 Plakophilin 4 Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein	A0A286ZJE7 A0A286ZKN5 A0A286ZKZ0 A0A286ZL11 A0A286ZP19 A0A286ZP27 A0A286ZU26 A0A286ZZR0 A0A287A191 A0A287A2G9 A0A287A2X0 A0A287A7I5 A0A287ABD5 A0A287AC61 A0A287AEE2 A0A287AEQ9 A0A287AG48 A0A287AIV8 A0A287AJK4 A0A287ALM4 A0A287AQ18 A0A287AQ32 A0A287ARK0 A0A287ART4 A0A287ASU3 A0A287ATF2 A0A287AU29 A0A287AWN2 A0A287AWU6 A0A287AXN9 A0A287B7K6 A0A287B9E4 A0A287BBT4 A0A287BCH5 A0A287BCS1 A0A287BEI1 A0A287BH52 A0A287BHT0 A0A287BHY5 A0A287BN15 A0A2C9F3E9 A0A480J3V8 A0A5G2QI29 A0A5G2QNX5 A0A5G2QPZ4 A0A5G2QSE8 A0A5G2QT86 A0A5G2QXD3 A0A5G2R2I1 A0A5G2R7N4 A0A5G2RBD3 A0A5G2RFR0 A0A5G2RJ22 A0A5G2RJ62 A0A8W4F965 A0A8W4FD39 A0A8W4FFK8 A0A8W4FM80 F1RW75 F1RXF9 F1RXG0 F1RXG1 F1RXG2 F1RY33 F1RZX5 F1RZX6 F1RZX7 F1S0J5 F1S0K4 F1S0K7 F1SAM0 F1SGG3 F1SGG5 F1SGG6 F1SGI2 F1SGI3 F1SGI4 F1SGI7 F1SGI8 F6PWF7 I3L5C4 I3L5R5 I3L6B5 I3L787 I3LA65 I3LDS3 I3LFN8 I3LGN8 I3LH42 I3LHI0 I3LK01 I3LQH1 I3LR68 I3LU54 Q3BDI7 Q8WNW3	DSC1 DSC2 DSC3 DSG1 DSG2 DSG3 DSG4 DSP JUP Jup KRT1 KRT10 KRT12 KRT15 KRT17 KRT18 KRT19 KRT2 KRT20 KRT23 KRT24 KRT25 KRT26 KRT27 KRT28 KRT3 KRT31 KRT32 KRT33A KRT34 KRT35 KRT36 KRT39 KRT4 KRT40 KRT5 KRT6A KRT7 KRT71 KRT72 KRT73 KRT74 KRT75 KRT77 KRT78 KRT79 KRT80 KRT82 KRT84 KRT85 KRTAP11-1 KRTAP24-1 KRTAP8-1 LOC100515166 LOC100516036 LOC100517674 LOC100518807 LOC100523123 LOC100523275 LOC100523670 LOC100621639 LOC100621844 LOC100622826 LOC100623393 LOC100625168 LOC100625858 LOC100737483 LOC102160031 LOC102164863 LOC106504189 LOC106507258 LOC106508044 LOC110255272 LOC110255312 LOC110256008 LOC110256282 LOC110260665 PKP1 PKP2 PKP3 PKP4	Sus scrofa (pig)
PTK6 promotes HIF1A stabilization	Glycoprotein nmb Hypoxia-inducible factor 1-alpha Proheparin-binding EGF-like growth factor Receptor protein-tyrosine kinase Tyrosine-protein kinase non-specific serine/threonine protein kinase	A0A286ZJF6 A0A286ZYS4 A0A287B2Q0 A0A5G2QBP1 F1SHN7 Q01580	DTR EGFR GPNMB HBEGF HEGFL HIF1A LRRK2 PTK6	Sus scrofa (pig)
EGFR Transactivation by Gastrin	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Proheparin-binding EGF-like growth factor Protein kinase C Receptor protein-tyrosine kinase SOS Ras/Rac guanine nucleotide exchange factor 1 Stromelysin-1 small monomeric GTPase	A0A286ZUQ0 A0A5G2QBP1 A0A5G2QLX0 B6E241 F1RV14 F1SV58 I3LCQ9 Q01580 Q2MJK3	DTR EGFR GRB2 HBEGF HEGFL HRAS KRAS MMP3 NRAS PRKCA SOS1	Sus scrofa (pig)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6 Toll/interleukin-1 receptor domain-containing adapter protein	A0A287A8A9 A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TIRAP TRAF6	Sus scrofa (pig)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TRAF6	Sus scrofa (pig)
MyD88 cascade initiated on plasma membrane	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TRAF6	Sus scrofa (pig)
Lysosphingolipid and LPA receptors	Lysophosphatidic acid protein 3 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 5 Phospholipid phosphatase related 2 Phospholipid phosphatase related 3 Phospholipid phosphatase related 4 Phospholipid phosphatase related 5 Phospholipid phosphatase-related protein type 1 Sphingosine 1-phosphate receptor 1 Sphingosine 1-phosphate receptor 2 Sphingosine 1-phosphate receptor 4 Sphingosine 1-phosphate receptor 5 Sphingosine-1-phosphate receptor 3 Sphingosine-1-phosphate receptor 5	A0A286ZX94 A0A287A2Q3 A0A287ABI5 A0A287AMV0 A0A287BF79 A0A5G2R5A5 C5G5X7 F1RN19 F1S3I6 F1S553 F1S8F0 F1SA14 F1SNC8 I3LIS0 Q684M3	EDG7 EDG8 LPA3 LPAR1 LPAR2 LPAR3 LPAR5 PLPPR1 PLPPR2 PLPPR3 PLPPR4 PLPPR5 S1PR1 S1PR2 S1PR3 S1PR4 S1PR5	Sus scrofa (pig)
Toll Like Receptor 9 (TLR9) Cascade	Early endosome antigen 1 Phosphatidylinositol 3-kinase catalytic subunit type 3 Rabenosyn, RAB effector Toll-like receptor 9 non-specific serine/threonine protein kinase	A0A287AVI7 A0A287BHR8 A0A5G2RJ76 F1SAI0 Q5I2M3	EEA1 PIK3C3 PIK3R4 RBSN TLR9	Sus scrofa (pig)
Elastic fibre formation	Elastin Fibrillin 2 Fibrillin 3 Fibulin-5 Lysyl oxidase homolog Lysyl oxidase homolog Lysyl oxidase homolog Microfibril associated protein 2 Microfibril associated protein 5 furin protein-lysine 6-oxidase protein-lysine 6-oxidase	A0A287AM88 A0A287AXU0 A0A5G2QM06 A0A5G2QNS3 A0A5G2R2Y0 F1RLC4 F1RMJ1 F1S8X0 F1SD87 F1SIC9 F1SNV7 I3LI73	ELN FBLN5 FBN2 FBN3 FURIN LOX LOXL1 LOXL2 LOXL3 LOXL4 MFAP2 MFAP5	Sus scrofa (pig)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	A0A286ZW95 I3LLY2 Q58D68	ENPP6 GDE1 PNPLA6	Sus scrofa (pig)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K)	Erythropoietin receptor Erythropoietin GRB2 associated binding protein 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphoinositide 3-kinase regulatory subunit 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZR76 A0A287B726 A0A5K1UB41 A0A5K1UPW2 A0A8X9AEI7 F1RT53 F1SKR9 I3LJB7 K7GMT0 O19064 P49157 Q9MYZ9	EPO EPOR GAB1 IRS2 JAK2 LYN PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R5	Sus scrofa (pig)
Erythropoietin activates RAS	Erythropoietin receptor Erythropoietin Growth factor receptor bound protein 2 Insulin receptor substrate 2 Proto-oncogene vav Rap guanine nucleotide exchange factor 1 SHC-transforming protein 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A286ZQX2 A0A287B726 A0A5K1V5Y3 B6E241 F1RT53 F1S0W0 O19064 P49157 Q9MYZ9	EPO EPOR GRB2 IRS2 JAK2 LYN RAPGEF1 SHC1 VAV1	Sus scrofa (pig)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A287B726 F1RT53 O19064 Q9MYZ9	EPOR IRS2 JAK2 LYN	Sus scrofa (pig)
ESR-mediated signaling	Estrogen receptor beta Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Prostaglandin E synthase 3 Serine/threonine-protein phosphatase peptidylprolyl isomerase peptidylprolyl isomerase	A0A286ZKC5 A0A5G2QVN7 A0A8I8C3K7 A0A8W4FCG7 F1RM25 F1SL99 F1SRR6 O02705 Q29040	ESR ESR1 ESR2 FKBP4 FKBP5 HSP90A HSP90AA1 HSP90AB1 HSPCA NR3A1 PPP5C PTGES3	Sus scrofa (pig)

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