GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▲	Organism	GlyTouCan ID
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5K1UB41 B6E241 F1SB93 F1SKR9 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Sus scrofa (pig)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A480LMF4 B6E241 F1SB93 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PTPN11	Sus scrofa (pig)
Galactose catabolism	Galactose-1-phosphate uridylyltransferase galactokinase	A0A5G2QDU1 F1S3U0	GALK1 GALT	Sus scrofa (pig)	G93924TT
Synthesis, secretion, and deacylation of Ghrelin	Appetite-regulating hormone Appetite-regulating hormone Growth hormone 1 Insulin-like growth factor I Insulin Leptin Membrane bound O-acyltransferase domain containing 4 Platelet-activating factor acetylhydrolase Pro-glucagon Signal peptidase complex subunit 1 Signal peptidase complex subunit 2 Signal peptidase complex subunit 3 Somatotropin	A0A5S6G9F8 A0A5S6I4D7 A0A8W4FHV2 F1RX63 F1SUP2 F2Z5C8 G9M5N9 P01248 P01274 P01315 P16545 Q29406 Q9GKY5	GCG GH1 GHRL IGF1 INS LEP MBOAT4 OB OBS PLA2G7 SPCS1 SPCS2 SPCS3	Sus scrofa (pig)	G58161NS
Growth hormone receptor signaling	Growth hormone 1 Mitogen-activated protein kinase Mitogen-activated protein kinase Prolactin receptor Prolactin SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A287BAQ6 A0A480NH74 A0A5G2RG05 A0A5S6I4D7 F1RFI0 F1RT53 O19064 P01238 P01248 Q6JTA8	GH1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 SH2B1	Sus scrofa (pig)
Electric Transmission Across Gap Junctions	Gap junction gamma-1 protein Gap junction protein Gap junction protein Pannexin Pannexin	A0A287AL56 A0A287B8K3 A4GVD1 F1RXR8 F1RY20	GJA10 GJA7 GJC1 GJD2 PANX PANX1 PANX2	Sus scrofa (pig)
Intestinal hexose absorption	Sodium/glucose cotransporter 1 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 2 Solute carrier family 2, facilitated glucose transporter member 5	A0A287A2X6 A0A8W4FPK7 F1RLV1 O62786	GLUT2 SLC2A2 SLC2A5 SLC5A1	Sus scrofa (pig)	G58161NS G93924TT
Sensory perception of sweet, bitter, and umami (glutamate) taste	G protein subunit beta 3 Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 Inositol 1,4,5-trisphosphate receptor Taste 1 receptor member 1 Taste 2 receptor member 39 Taste receptor type 1 member 2 Taste receptor type 1 member 3 Taste receptor type 2 member 40 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2 Taste receptor type 2	A0A286ZVQ9 A0A287A3Q1 A0A287AA31 A0A287AFV6 A0A287AW90 A0A287AYK0 A0A287BL11 A0A480JCU5 A0A5G2QX37 A0A8W4F831 F1RIJ7 F1RJE6 F1SLU8 F1SSI6 I3LCT3 I3LE78 I3LF46	GNB1 GNB3 ITPR3 LOC100154902 TAS1R1 TAS1R2 TAS1R3 TAS2R1 TAS2R10 TAS2R16 TAS2R3 TAS2R39 TAS2R4 TAS2R40 TAS2R41 TAS2R7	Sus scrofa (pig)	G58161NS
TNFR1-mediated ceramide production	Neutral sphingomyelinase activation associated factor Small ribosomal subunit protein RACK1 Tumor necrosis factor receptor superfamily member 1A Tumor necrosis factor sphingomyelin phosphodiesterase sphingomyelin phosphodiesterase	A0A286ZVH7 A0A287A053 A0A287AXH1 F1RSY4 P23563 P63246	GNB2L1 NSMAF RACK1 SMPD2 SMPD3 TNF TNFA TNFRSF1A TNFSF2	Sus scrofa (pig)
Amine ligand-binding receptors	G-protein coupled receptor 143 G-protein coupled receptor 143	A0A286ZZS9 F1SG22	GPR143	Sus scrofa (pig)
Insulin receptor signalling cascade	Growth factor receptor bound protein 2 Growth factor receptor-bound protein 10 Insulin SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A5K1V5Y3 B5KFD7 B6E241 F1SCL0 P01315	GRB2 Grb10 INS INSR SHC1 SOS1	Sus scrofa (pig)
MET activates RAS signaling	GTPase HRas GTPase NRas Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Mucin 20, cell surface associated RAN binding protein 10 Ran-binding protein 9 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 small monomeric GTPase	A0A286ZUQ0 A0A5G2QLX0 A0A5K1V5Y3 B6E241 F1RV77 F1SB93 F6Q8N2 I3LCC3 I3LCQ9 Q2MJK3 Q2QLE0	GRB2 HGF HRAS KRAS MET MUC20 NRAS RANBP10 RANBP9 SHC1 SOS1	Sus scrofa (pig)
SHC-related events triggered by IGF1R	Growth factor receptor bound protein 2 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase receptor	A0A286ZUQ0 A0A287BJL7 A0A5K1V5Y3 B6E241 F1CK17 P16545 P23695	GRB2 IGF1 IGF1R IGF2 SHC1 SOS1	Sus scrofa (pig)
Digestion	Alkaline phosphatase Guanylate cyclase activator 2B Guanylin Guanylyl cyclase C Pirin	A0A287AF84 K7GKW6 O13009 P55204 P79897	GUC2C GUCA2 GUCA2A GUCA2B GUCY2C LOC100522404 PIR	Sus scrofa (pig)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor	A0A287A138 F1RUN6 F1S1T5 F1SUD0 O62809 O77668	HCRT HCRTR1 HCRTR2 NPFFR1 NPFFR2 ORX OX PPOX QRFPR	Sus scrofa (pig)
MET Receptor Activation	HGF activator Hepatocyte growth factor receptor Hepatocyte growth factor Hepsin Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type 2	A0A286ZMW3 A0A287BCY0 A0A287BHH9 A0A5G2R148 F1SB93 Q2QLE0	HGF HGFAC HPN MET SPINT1 SPINT2	Sus scrofa (pig)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin-4	F1RXE4 F1SB93 F1ST78 K7GQ83 Q2QLE0	HGF ITGB1 MET TNS3 TNS4	Sus scrofa (pig)
MET activates PTK2 signaling	Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein kinase	F1SB93 K7GPR7 Q2QLE0	HGF MET SRC	Sus scrofa (pig)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3 Signal transducer and activator of transcription	A0A2C9F3G4 F1SB93 Q19S50 Q2QLE0	HGF MET STAT3	Sus scrofa (pig)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	F1SB93 Q2QLE0	HGF MET	Sus scrofa (pig)
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral signaling protein Mitochondrial import receptor subunit TOM70 TANK binding kinase 1	A0A286ZKC5 A0A287AL42 A0A480UKD4 A0A5K1V3V4 A0A8I8C3K7 K7GM32 O02705	HSP90A HSP90AA1 HSP90AB1 HSPCA IRF3 MAVS TBK1 TOMM70	Sus scrofa (pig)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor Pannexin Thioredoxin-interacting protein Thioredoxin	A0A286ZKC5 A0A287B8K3 A0A5G2Q9S8 F1RNN5 H2EW08 Q2HY40	HSP90AB1 NLRP3 P2RX7 PANX PANX1 TXN TXNIP	Sus scrofa (pig)
Interleukin-4 and Interleukin-13 signaling	Endoplasmin Interleukin 13 receptor subunit alpha 1 Interleukin 13 receptor subunit alpha 2 Interleukin 2 receptor gamma Interleukin-13 Interleukin-4 receptor subunit alpha Interleukin-4 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Suppressor of cytokine signaling 1 Suppressor of cytokine signaling 5 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A286ZN85 A0A287AFA5 A0A2C9F3G4 E5F1H4 E5F1H9 E7CR04 F1RFF9 F1RU78 F1RWT5 F1S3L9 K7GSE8 O19064 Q04745 Q19S50 Q76KD0 Q95J68	HSP90B1 IL13 IL13RA1 IL13RA2 IL2RG IL4 IL4R JAK1 JAK2 JAK3 SOCS1 SOCS5 STAT1 STAT3 STAT6 TYK2 socs1	Sus scrofa (pig)
Costimulation by the CD28 family	Ig-like domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5G2QMX5 A0A5K1UB41 F1S916 F1SKR9	ICOSLG PIK3CA PIK3R1 PIK3R2	Sus scrofa (pig)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A286ZLI2 A0A287B963 A0A480NH74 A0A5G2RG05 F1S692 O19064 P17803	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3	Sus scrofa (pig)

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