GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **301 - 325** of **360** in total

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Pathway Name	Protein Name	UniProt ID ▲	Gene Symbol	Organism	GlyTouCan ID
Muscarinic acetylcholine receptors	Muscarinic acetylcholine receptor M1 Muscarinic acetylcholine receptor M2 Muscarinic acetylcholine receptor M3 Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor Muscarinic acetylcholine receptor	A0A287B5F2 A0A287BAI1 F1SIA0 P04761 P06199 P11483	CHRM1 CHRM2 CHRM3 CHRM4 CHRM5	Sus scrofa (pig)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A287B726 A0A287BJL7 A0A5K1VEI3 F1CK17 I3LLF1 P16545 P23695	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Sus scrofa (pig)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287B726 A0A5K1UB41 A0A8X9AEI7 F1S916 F1SKR9 I3LLF1	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Sus scrofa (pig)
Signaling by Erythropoietin	Erythropoietin receptor Insulin receptor substrate 2 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A287B726 F1RT53 O19064 Q9MYZ9	EPOR IRS2 JAK2 LYN	Sus scrofa (pig)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	ALG14 UDP-N-acetylglucosaminyltransferase subunit Alpha-1,3-glucosyltransferase Alpha-1,3/1,6-mannosyltransferase ALG2 Chitobiosyldiphosphodolichol beta-mannosyltransferase isoform 1 Dol-P-Man Mannose-P-dolichol utilization defect 1 protein Mannosyltransferase Mannosyltransferase N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase	A0A287B9F4 A0A5G2RAN8 F1RKX2 F1RXR3 F1S544 F1SAH5 F1SSE6 F6Q635 I3L8Z7 I3LQI7	ALG1 ALG12 ALG14 ALG2 ALG3 ALG8 ALG9 DPAGT1 MPDU1	Sus scrofa (pig)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	DEK proto-onco Transcription factor AP-2-alpha	A0A287B9K7 A0A5G2QII0	DEK TFAP2A	Sus scrofa (pig)
Growth hormone receptor signaling	Growth hormone 1 Mitogen-activated protein kinase Mitogen-activated protein kinase Prolactin receptor Prolactin SH2B adaptor protein 1 Somatotropin Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type	A0A287BAQ6 A0A480NH74 A0A5G2RG05 A0A5S6I4D7 F1RFI0 F1RT53 O19064 P01238 P01248 Q6JTA8	GH1 JAK2 LYN MAPK1 MAPK3 PRL PRLR PTPN1 SH2B1	Sus scrofa (pig)
Transport of vitamins, nucleosides, and related molecules	PDZ domain-containing protein 11 Sodium-dependent multivitamin transporter Solute carrier family 33 member 1	A0A287BEL5 I3LE73 Q6QA76	PDZD11 PDZK11 SLC33A1 SLC5A6	Sus scrofa (pig)
Lactose synthesis	Alpha-lactalbumin Beta-1,4-galactosyltransferase Solute carrier family 2, facilitated glucose transporter member 1	A0A287BG16 P18137 P20303	B4GALT1 GLUT1 LALBA SLC2A1	Sus scrofa (pig)	G58161NS G74621DY
FGFR1b ligand binding and activation	Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein Transforming growth factor beta receptor 3	A0A287BG34 A0A287BGK8 A0A287BPI7 F1RM38 F1RY78 F1SMG2 K7GQJ1	FGF1 FGF10 FGF2 FGF22 FGF3 FGFR1 TGFBR3	Sus scrofa (pig)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A287BJL7 A0A287BRX8 F1CK17 P16545 P23695	CILP IGF1 IGF1R IGF2	Sus scrofa (pig)
Assembly of active LPL and LIPC lipase complexes	Angiopoietin like 3 Angiopoietin like 8 Angiopoietin-related protein 4 Hepatic triacylglycerol lipase Lipase maturation factor Lipase maturation factor Lipoprotein lipase Proprotein convertase subtilisin/kexin type 6 furin	A0A287BK80 A0A287BRD2 A0A480KVF0 F1RMJ1 F1RZ92 F1RZH2 F1S7Z7 Q2TNK5 T1UNN8	ANGPTL3 ANGPTL4 ANGPTL8 FURIN LIPC LMF1 LMF2 LPL PCSK6 PGAR	Sus scrofa (pig)
Ligand-dependent caspase activation	Caspase-8 FAS-associated death domain protein Lymphocyte antigen 96 Monocyte differentiation antigen CD14 Receptor interacting serine/threonine kinase 1 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A0A287BMU9 A0A287BRT1 A0A480K9W0 A2SW51 A7BG67 K9J6H0 Q56VC2 Q56VC3	CASP8 CD14 FADD LY96 RIPK1 TICAM1 TICAM2 TLR4 TNFRSF6	Sus scrofa (pig)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A0A287BMU9 A0A480K9W0 A2SW51 A7BG67 K9J6H0	CD14 LY96 TICAM1 TICAM2 TLR4	Sus scrofa (pig)
CASP8 activity is inhibited	Caspase 9 Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A287BPE4 A0A287BRT1 F1RVZ4 F1SCY7 F1SUV9 O77736 Q56VC2 Q56VC3	APT1 CASP8 CASP9 FADD FAS RIPK1 TNFRSF6 TRADD TRAF2	Sus scrofa (pig)
Antagonism of Activin by Follistatin	Follistatin Follistatin Inhibin beta A chain Inhibin beta B chain	A0A287BPF5 F1SLQ4 P03970 P10669	FST INHBA INHBB	Sus scrofa (pig)
Cilium Assembly	Alpha-tubulin N-acetyltransferase 1 Histone deacetylase 6	A0A287BPX4 I3L925	ATAT1 HDAC6 MEC17	Sus scrofa (pig)
RUNX3 regulates p14-ARF	Core-binding factor subunit beta G1/S-specific cyclin-D1 Histone deacetylase Runt-related transcription factor Transforming growth factor beta-1 proprotein histone acetyltransferase	A0A287BQF9 A0A287BRJ4 A0A5G2QVF3 A0A5G2R2L4 I3L9U8 P07200	CBFB CCND1 EP300 HDAC4 RUNX3 TGFB1	Sus scrofa (pig)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin	A0A287BQI1 F1S135 F1SEP7 I3LTK7 O18766 Q5IR81	LOC494564 OPN4 OPN5 RGR RHO RHO1 RRH	Sus scrofa (pig)
Toll Like Receptor 7/8 (TLR7/8) Cascade	Toll like receptor 7	A0A288CG39	TLR7	Sus scrofa (pig)
Adrenoceptors	Alpha-1A adrenergic receptor Alpha-1B adrenergic receptor Alpha-1D adrenergic receptor Alpha-1D adrenergic receptor Alpha-2A adrenergic receptor Alpha-2B adrenergic receptor Alpha-2C adrenergic receptor Beta-1 adrenergic receptor Beta-2 adrenergic receptor Beta-3 adrenergic receptor Beta-3 adrenergic receptor	A0A2C9F3F6 A7BJW1 F1RR36 F1S5H5 F1S8D0 I3LFJ1 P18871 Q38PT0 Q95252 Q9TSW7 Q9TTM9	A2AR ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 BAR3 alpha-1A	Sus scrofa (pig)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A2C9F3G4 A0A5G2QAF8 A0A5G2R3H9 A0A5G2RDD7 E1U8C4 F1S3L9 O19064 Q19S50 Q28938 Q9N2H9	IL12B IL12RB1 IL23A IL23R JAK2 LOC100736717 P4HB SGRF STAT3 STAT4 TYK2 stat4	Sus scrofa (pig)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3 Signal transducer and activator of transcription	A0A2C9F3G4 F1SB93 Q19S50 Q2QLE0	HGF MET STAT3	Sus scrofa (pig)
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	alpha-1,2-Mannosidase alpha-1,2-Mannosidase alpha-1,2-Mannosidase	A0A480JM90 A0A481C5C8 I3L826	MAN1A1 MAN1A2 MAN1C1	Sus scrofa (pig)	G70323CJ
Signal regulatory protein family interactions	FYN binding protein 1 Growth factor receptor bound protein 2 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Leukocyte surface antigen CD47 Signal regulatory protein alpha Src kinase-associated phosphoprotein 2 TYRO protein tyrosine kinase-binding protein non-specific protein-tyrosine kinase	A0A480KBE3 A0A8W4FCP5 B6E241 F1RJS6 I3L932 K7GKB0 K7GL06 K7GLT9 M9MMN6 Q9GKE8 Q9TU45	CD47 DAP12 FYB1 GRB2 LOC100736623 LOC100739707 LOC102161654 PTK2B SIRPA SKAP2 TYROBP	Sus scrofa (pig)

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