GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **360** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Gastrin-CREB signalling pathway via PKC and MAPK	Mitogen-activated protein kinase Mitogen-activated protein kinase Mitogen-activated protein kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase Ribosomal protein S6 kinase	A0A287A3K5 A0A287BHE2 A0A480NH74 A0A5G2R6J0 A0A5G2RG05 M3VH78	MAPK1 MAPK3 MAPK7 RPS6KA1 RPS6KA2 RPS6KA3	Sus scrofa (pig)
Lysosphingolipid and LPA receptors	Lysophosphatidic acid protein 3 Lysophosphatidic acid receptor 1 Lysophosphatidic acid receptor 2 Lysophosphatidic acid receptor 5 Phospholipid phosphatase related 2 Phospholipid phosphatase related 3 Phospholipid phosphatase related 4 Phospholipid phosphatase related 5 Phospholipid phosphatase-related protein type 1 Sphingosine 1-phosphate receptor 1 Sphingosine 1-phosphate receptor 2 Sphingosine 1-phosphate receptor 4 Sphingosine 1-phosphate receptor 5 Sphingosine-1-phosphate receptor 3 Sphingosine-1-phosphate receptor 5	A0A286ZX94 A0A287A2Q3 A0A287ABI5 A0A287AMV0 A0A287BF79 A0A5G2R5A5 C5G5X7 F1RN19 F1S3I6 F1S553 F1S8F0 F1SA14 F1SNC8 I3LIS0 Q684M3	EDG7 EDG8 LPA3 LPAR1 LPAR2 LPAR3 LPAR5 PLPPR1 PLPPR2 PLPPR3 PLPPR4 PLPPR5 S1PR1 S1PR2 S1PR3 S1PR4 S1PR5	Sus scrofa (pig)
MyD88-independent TLR4 cascade	Lymphocyte antigen 96 Monocyte differentiation antigen CD14 TIR domain-containing adapter molecule 1 TIR domain-containing adapter molecule 2 Toll-like receptor 4	A0A287BMU9 A0A480K9W0 A2SW51 A7BG67 K9J6H0	CD14 LY96 TICAM1 TICAM2 TLR4	Sus scrofa (pig)
Opsins	Long-wave-sensitive opsin 1 Melanopsin Opsin 5 Retinal G protein coupled receptor Retinal pigment epithelium-derived rhodopsin homolog Rhodopsin	A0A287BQI1 F1S135 F1SEP7 I3LTK7 O18766 Q5IR81	LOC494564 OPN4 OPN5 RGR RHO RHO1 RRH	Sus scrofa (pig)
Interleukin-2 signaling	Interleukin 2 receptor gamma Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 SHC-transforming protein 1 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase non-specific protein-tyrosine kinase	A0A0A0MY60 A0A286ZLI2 A0A287A7A4 A0A287AFR0 A0A5K1V5Y3 E7CR01 F1RJS6 F1SV94 K7GSE8 P26891 Q76KD0	IL2 IL2RA IL2RB IL2RG JAK1 JAK3 LCK PTK2B SHC1 STAT5A STAT5B stat5B	Sus scrofa (pig)
Interleukin-23 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 23 receptor Interleukin-12 subunit beta Interleukin-23 subunit alpha Protein disulfide-isomerase Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A2C9F3G4 A0A5G2QAF8 A0A5G2R3H9 A0A5G2RDD7 E1U8C4 F1S3L9 O19064 Q19S50 Q28938 Q9N2H9	IL12B IL12RB1 IL23A IL23R JAK2 LOC100736717 P4HB SGRF STAT3 STAT4 TYK2 stat4	Sus scrofa (pig)
Interleukin-12 signaling	Interleukin 12 receptor subunit beta 1 Interleukin 12 receptor subunit beta 2 Interleukin-12 subunit alpha Interleukin-12 subunit beta Protein disulfide-isomerase Signal transducer and activator of transcription Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A5G2QAF8 A0A5G2RDD7 A0A5S6GA10 E1U8C4 F1S3L9 F1S826 O19064 Q28938	IL12A IL12B IL12RB1 IL12RB2 JAK1 JAK2 LOC100736717 P4HB STAT4 TYK2 stat4	Sus scrofa (pig)
Interleukin-10 signaling	Interleukin 10 receptor subunit alpha Interleukin-10 receptor subunit beta Interleukin-10 Signal transducer and activator of transcription 3 Signal transducer and activator of transcription Tyrosine-protein kinase Tyrosine-protein kinase	A0A286ZLI2 A0A286ZQU5 A0A2C9F3G4 F1S3L9 F1SAM5 Q19S50 Q29055	IL10 IL10RA IL10RB JAK1 STAT3 TYK2	Sus scrofa (pig)
IFNG signaling activates MAPKs	Interferon gamma receptor 1 Interferon gamma receptor 2 Interferon gamma Mitogen-activated protein kinase Mitogen-activated protein kinase Tyrosine-protein kinase JAK2 Tyrosine-protein kinase	A0A286ZLI2 A0A287B963 A0A480NH74 A0A5G2RG05 F1S692 O19064 P17803	IFNG IFNGR1 IFNGR2 JAK1 JAK2 MAPK1 MAPK3	Sus scrofa (pig)
Signaling by Insulin receptor	Insulin Tyrosine-protein kinase receptor	F1SCL0 P01315	INS INSR	Sus scrofa (pig)
IRS-mediated signalling	Insulin receptor substrate 1 Insulin receptor substrate 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A287B726 A0A5K1UB41 A0A8X9AEI7 F1S916 F1SKR9 I3LLF1	IRS1 IRS2 PIK3CA PIK3CB PIK3R1 PIK3R2	Sus scrofa (pig)
IRS-related events triggered by IGF1R	Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor substrate 4 Insulin-like growth factor I Insulin-like growth factor II Insulin-like growth factor II Tyrosine-protein kinase receptor	A0A287B726 A0A287BJL7 A0A5K1VEI3 F1CK17 I3LLF1 P16545 P23695	IGF1 IGF1R IGF2 IRS1 IRS2 IRS4	Sus scrofa (pig)
Elevation of cytosolic Ca2+ levels	Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 isoform a Transient receptor potential cation channel subfamily C member 6 Transient receptor potential cation channel subfamily C member 7	A0A286ZYA9 A0A287AVK8 A0A287BL11 A0A5G2QGJ3 A0A5G2QQ93 A0A5G2RCE3 A0A8W4FN26 F1RI70 F1RNN5 F1S1U0 I3L7H5 I3LUU3	ITPR1 ITPR3 P2RX1 P2RX2 P2RX3 P2RX4 P2RX5 P2RX6 P2RX7 TRPC3 TRPC6 TRPC7	Sus scrofa (pig)
Signaling by Activin	Inhibin alpha chain Inhibin beta A chain Inhibin beta B chain Mitogen-activated protein kinase Mitogen-activated protein kinase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Transforming growth factor beta receptor 3 receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A287AAP7 A0A287BE69 A0A287BJX6 A0A287BPF5 A0A287BPI7 A0A480NH74 A0A5G2RG05 A0A5K1U747 F1S0H6 P03970 P04087 P84024 Q9GKQ9	ACVR1B ACVR1C ACVR2A ACVR2B INHA INHBA INHBB MADH3 MADH4 MAPK1 MAPK3 SMAD2 SMAD3 SMAD4 TGFBR3	Sus scrofa (pig)
Costimulation by the CD28 family	Ig-like domain-containing protein Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5G2QMX5 A0A5K1UB41 F1S916 F1SKR9	ICOSLG PIK3CA PIK3R1 PIK3R2	Sus scrofa (pig)
Translocation of ZAP-70 to Immunological synapse	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Uncharacterized protein protein-tyrosine-phosphatase	A0A286ZKB7 A0A286ZUJ9 A0A287AC24 A0A287AT33 A0A287B968 A0A287BD80 A0A287BF11 A0A287BQ31 A0A5G2QCN4 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1S6S1 F1S975 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 DRA HLA-DRA LCK LOC100153139 PTPN22 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
PD-1 signaling	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Programmed cell death 1 ligand 2 Programmed cell death 1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type Uncharacterized protein	A0A286ZKB7 A0A286ZUJ9 A0A287A1C3 A0A287AC24 A0A287AT33 A0A287B968 A0A287BF11 A0A287BQ31 A0A480LMF4 A0A5G2QCN4 A0A5G2QPQ3 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1S6S1 F1S975 F1SJ27 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 CSK DRA HLA-DRA LCK LOC100153139 PDCD1 PDCD1LG2 PTPN11 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
Phosphorylation of CD3 and TCR zeta chains	Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Phosphoprotein membrane anchor with glycosphingolipid microdomains 1 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 Tyrosine-protein kinase Tyrosine-protein kinase Uncharacterized protein protein-tyrosine-phosphatase protein-tyrosine-phosphatase	A0A286ZKB7 A0A286ZUJ9 A0A287AC24 A0A287AT33 A0A287B968 A0A287BD80 A0A287BF11 A0A287BQ31 A0A5G2QCN4 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FP49 A0A8X9AEU9 F1RXA1 F1S5F1 F1S6S1 F1S975 F1SJ27 F1SV94 I3L556 I3LAQ5 K7GS60 P15981 Q5PXD3 Q764N2 Q7YQ94 Q85ZW4	CD247 CD3D CD3E CD3G CD4 CSK DRA HLA-DRA LCK LOC100153139 PAG1 PTPN22 PTPRC SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1	Sus scrofa (pig)
Orexin and neuropeptides FF and QRFP bind to their respective receptors	Hypocretin neuropeptide precursor Neuropeptide FF receptor 1 Neuropeptide FF receptor 2 Orexin receptor type 2 Orexin/Hypocretin receptor type 1 Pyroglutamylated RFamide peptide receptor	A0A287A138 F1RUN6 F1S1T5 F1SUD0 O62809 O77668	HCRT HCRTR1 HCRTR2 NPFFR1 NPFFR2 ORX OX PPOX QRFPR	Sus scrofa (pig)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 RAS related Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Semaphorin 4D Transforming protein RhoA	A0A5K1TV69 A0A8W4FI56 F1RHW4 F1RM07 F1SLI0 I3LVS7 Q2QLE0	ARHGAP35 MET PLXNB1 RAC1 RHOA RRAS SEMA4D	Sus scrofa (pig)
Drug-mediated inhibition of MET activation	Hepatocyte growth factor receptor Hepatocyte growth factor	F1SB93 Q2QLE0	HGF MET	Sus scrofa (pig)
MET activates PTK2 signaling	Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein kinase	F1SB93 K7GPR7 Q2QLE0	HGF MET SRC	Sus scrofa (pig)
MET activates STAT3	Hepatocyte growth factor receptor Hepatocyte growth factor Signal transducer and activator of transcription 3 Signal transducer and activator of transcription	A0A2C9F3G4 F1SB93 Q19S50 Q2QLE0	HGF MET STAT3	Sus scrofa (pig)
MET interacts with TNS proteins	Hepatocyte growth factor receptor Hepatocyte growth factor Integrin beta Tensin 3 Tensin-4	F1RXE4 F1SB93 F1ST78 K7GQ83 Q2QLE0	HGF ITGB1 MET TNS3 TNS4	Sus scrofa (pig)
The NLRP3 inflammasome	Heat shock protein HSP 90-beta NACHT, LRR and PYD domains-containing protein 3 P2X purinoceptor Pannexin Thioredoxin-interacting protein Thioredoxin	A0A286ZKC5 A0A287B8K3 A0A5G2Q9S8 F1RNN5 H2EW08 Q2HY40	HSP90AB1 NLRP3 P2RX7 PANX PANX1 TXN TXNIP	Sus scrofa (pig)

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