GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **101 - 125** of **360** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
DDX58/IFIH1-mediated induction of interferon-alpha/beta	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Interferon regulatory factor 3 Mitochondrial antiviral signaling protein Mitochondrial import receptor subunit TOM70 TANK binding kinase 1	A0A286ZKC5 A0A287AL42 A0A480UKD4 A0A5K1V3V4 A0A8I8C3K7 K7GM32 O02705	HSP90A HSP90AA1 HSP90AB1 HSPCA IRF3 MAVS TBK1 TOMM70	Sus scrofa (pig)
Activated NTRK2 signals through FRS2 and FRS3	Brain-derived neurotrophic factor Growth factor receptor bound protein 2 Neurotrophin-4 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A286ZUQ0 B6E241 F1RIN3 P14082	BDNF GRB2 NTF4 SOS1	Sus scrofa (pig)
PECAM1 interactions	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Integrin beta Integrin subunit alpha V Platelet and endothelial cell adhesion molecule 1 Platelet endothelial cell adhesion molecule Tyrosine-protein kinase Fyn Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase	A0A287ABR0 A0A480LMF4 A0A5G2QU81 A0A5G2R7K7 A0A5K1V6L8 A1Y2K1 F1RT53 F1SDV6 F1SV94 K7GPR7 K7GS31 Q95242	FYN INPP5D ITGAV ITGB3 LCK LYN PECAM1 PLCG1 PTPN11 SRC YES1	Sus scrofa (pig)
Metabolism of Angiotensinogen to Angiotensins	Aminopeptidase Angiotensin-converting enzyme Angiotensin-converting enzyme Angiotensinogen Carboxylesterase 1 Carboxylic ester hydrolase Carboxylic ester hydrolase Cathepsin D Glutamyl aminopeptidase Neprilysin Peptidase S1 domain-containing protein Peptidase S1 domain-containing protein Renin receptor cathepsin X renin	A0A286ZX26 A0A287A8N2 A0A287AJ51 A0A287APG1 A0A287BDI2 A0A5G2QAJ2 A0A5G2QWJ0 A0A5G2R0G8 A0A8W4FP09 A5GFX7 F1RF16 F1RRW5 I3LDA9 K7GLM4 Q95334	ACE ACE2 AGT ATP6AP2 CES1 CTSD CTSZ ENPEP LOC100154047 LOC100736962 MME REN	Sus scrofa (pig)
FGFR4 ligand binding and activation	Fibroblast growth factor 23 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Multifunctional fusion protein	A0A287AFX3 A0A287AXR0 A0A287B3V5 A0A287BGK8 A0A5G2QUY7 A0A5G2R7G2 F1RM38 F1RY80 F1S3B8 F1SET9 I3LR27 Q95L12	FGF1 FGF16 FGF18 FGF19 FGF2 FGF20 FGF23 FGF4 FGF6 FGF8 FGF9 FGFR4 Fgf4	Sus scrofa (pig)
Regulation of RUNX3 expression and activity	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 Core-binding factor subunit beta E3 ubiquitin-protein ligase Mdm2 E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Polyubiquitin-C Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Runt-related transcription factor Transforming growth factor beta-1 proprotein Tyrosine-protein kinase Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein histone acetyltransferase	A0A286ZIP0 A0A286ZLP7 A0A286ZN52 A0A286ZS34 A0A287AEH0 A0A287ATZ7 A0A287AZA7 A0A287B5Q7 A0A287BG14 A0A287BPP9 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A2C9F3G2 A0A480JRT9 A0A5G2QI19 A0A5G2QL81 A0A5G2QSU8 A0A5G2QVF3 A0A5G2R2L4 A0A5G2R6X9 A0A8W4FHK5 A0A8W4FNV3 A1XQU1 A7U5U2 F1RKW8 F1RPQ3 F1RXA7 F1S911 F1SGF1 F1SGM3 F1SMW9 F2Z5J1 F2Z5K2 F2Z5N0 I3L9U8 I3LTD6 K7GPR7 P07200 P0CG68 P61291 P62197 Q2PYM7 Q64L94	CBFB EP300 LMP2 MDM2 PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMB1 PSMB10 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSMF1 RPS27A RUNX3 SMURF1 SMURF2 SRC TGFB1 UBA52 UBB UBC	Sus scrofa (pig)
CDC42 GTPase cycle	ADP-ribosylation factor GTPase-activating protein 2 ADP-ribosylation factor GTPase-activating protein 3 Active breakpoint cluster region-related protein Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 BCR activator of RhoGEF and GTPase Brain-specific angiogenesis inhibitor 1-associated protein 2 CDC42 effector protein 1 CDC42 effector protein 3 CDC42 effector protein 4 CDC42 effector protein 5 CDC42 small effector protein 2 Caveolin Cdc42 effector protein 2 Cell division control protein 42 homolog Chimaerin Copine-8 DEF6 guanine nucleotide exchange factor DEP domain containing 1B Dedicator of cytokinesis 10 Dedicator of cytokinesis 11 Dedicator of cytokinesis 6 Dedicator of cytokinesis 7 Dedicator of cytokinesis 8 Dedicator of cytokinesis 9 Delta(14)-sterol reductase LBR Diaphanous related formin 3 Dishevelled associated activator of morphosis 1 Dynamin-binding protein Epithelial cell transforming 2 FERM, ARHGEF and pleckstrin domain-containing protein 1 FYVE, RhoGEF and PH domain containing 1 FYVE, RhoGEF and PH domain containing 2 FYVE, RhoGEF and PH domain containing 3 FYVE, RhoGEF and PH domain containing 4 Family with sequence similarity 13 member B Formin binding protein 1 Formin like 1 Formin like 2 Formin like 3 Formin-binding protein 1-like G protein subunit alpha 13 GEM interacting protein GIT ArfGAP 1 GIT ArfGAP 2 Golgin subfamily A conserved domain-containing protein Guanine nucleotide exchange factor DBS isoform X2 IQ motif containing GTPase activating protein 2 IQ motif containing GTPase activating protein 3 Intersectin 1 Junction plakoglobin Junction plakoglobin Kinectin 1 MCF.2 cell line derived transforming sequence Mitogen-activated protein kinase kinase kinase Myosin IXB Neuronal guanine nucleotide exchange factor Oligophrenin-1 Par-6 family cell polarity regulator alpha Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 2 Phospholipase Pleckstrin homology and RhoGEF domain containing G1 Pleckstrin homology and RhoGEF domain containing G2 Pleckstrin homology and RhoGEF domain containing G3 Potassium channel tetramerization domain containing 3 Rac GTPase activating protein 1 Rac/Cdc42 guanine nucleotide exchange factor 6 Ragulator complex protein LAMTOR1 Ras protein specific guanine nucleotide releasing factor 2 Ras-related protein Rab-7a Rho GDP dissociation inhibitor gamma Rho GDP-dissociation inhibitor 1 Rho GTPase activating protein 17 Rho GTPase activating protein 1 Rho GTPase activating protein 20 Rho GTPase activating protein 21 Rho GTPase activating protein 22 Rho GTPase activating protein 24 Rho GTPase activating protein 27 Rho GTPase activating protein 30 Rho GTPase activating protein 31 Rho GTPase activating protein 33 Rho GTPase activating protein 39 Rho GTPase activating protein 44 Rho GTPase activating protein 45 Rho GTPase activating protein 4 Rho GTPase activating protein 5 Rho GTPase activating protein 9 Rho GTPase-activating protein 10 Rho GTPase-activating protein 26 Rho GTPase-activating protein 29 Rho GTPase-activating protein 35 Rho GTPase-activating protein 7 Rho guanine nucleotide exchange factor 10 Rho guanine nucleotide exchange factor 11 Rho guanine nucleotide exchange factor 12 Rho guanine nucleotide exchange factor 15 Rho guanine nucleotide exchange factor 16 Rho guanine nucleotide exchange factor 19 Rho guanine nucleotide exchange factor 25 Rho guanine nucleotide exchange factor 26 Rho guanine nucleotide exchange factor 5 Rho guanine nucleotide exchange factor 7 Rho guanine nucleotide exchange factor 9 SH3 and PX domain-containing protein 2A SH3KBP1 binding protein 1 SLIT-ROBO Rho GTPase activating protein 1 SLIT-ROBO Rho GTPase activating protein 2 SLIT-ROBO Rho GTPase activating protein 3 STEAP3 metalloreductase Scribble planar cell polarity protein StAR related lipid transfer domain containing 8 Stomatin Synapse defective Rho GTPase homolog 1 Synaptosomal-associated protein T cell activation RhoGTPase activating protein TIAM Rac1 associated GEF 1 Transferrin receptor protein 1 Transferrin receptor protein 1 Vang-like protein Vav guanine nucleotide exchange factor 2 Vesicle-associated membrane protein 3 WASP like actin nucleation promoting factor WD repeat domain 81 WD repeat-containing protein 91 WH2 domain-containing protein YKT6 v-SNARE homolog non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A286ZJI5 A0A286ZJP1 A0A286ZJQ9 A0A286ZMP2 A0A286ZN71 A0A286ZPM4 A0A286ZQB5 A0A286ZUE0 A0A286ZWS2 A0A286ZYD7 A0A286ZZ01 A0A286ZZA8 A0A286ZZD3 A0A287A7V4 A0A287A853 A0A287A8W6 A0A287AAM5 A0A287AEN9 A0A287AFT4 A0A287AGS3 A0A287AH65 A0A287AHK8 A0A287AI32 A0A287AIC4 A0A287AIM9 A0A287ALB3 A0A287AMB8 A0A287APY3 A0A287ART1 A0A287AV01 A0A287AV56 A0A287AVY9 A0A287AZG0 A0A287B0J2 A0A287B2Q3 A0A287B310 A0A287B3E0 A0A287B6K8 A0A287B8N4 A0A287B9E3 A0A287BEC7 A0A287BEY0 A0A287BGM7 A0A287BKX8 A0A287BLK5 A0A287BPQ3 A0A287BSE0 A0A287BSS5 A0A287BT14 A0A287BT99 A0A2C9F3E9 A0A480JSC9 A0A480KQN9 A0A480LCB3 A0A480P3R5 A0A481A732 A0A5G2QA45 A0A5G2QFN5 A0A5G2QPS5 A0A5G2QVJ5 A0A5G2QWD7 A0A5G2QXS5 A0A5G2R1A0 A0A5G2R4C3 A0A5G2R661 A0A5G2RET7 A0A5G2REY5 A0A5K1U8N6 A0A5K1VSS6 A0A5S6GXI4 A0A8W4FAC1 A0A8W4FG77 A0A8W4FJM1 A0A8W4FMP1 A0A8W4FMS3 A0A8W4FQ33 A0A8W4FQG7 E7EI20 F1RF08 F1RJ64 F1RM07 F1RN87 F1RQ74 F1RQV5 F1RR27 F1RS73 F1RSQ1 F1RU77 F1RUG2 F1RV35 F1RW15 F1RZ09 F1S291 F1S4M1 F1S4Q9 F1S535 F1S540 F1S916 F1SA91 F1SAN7 F1SAW7 F1SB58 F1SEG8 F1SEU3 F1SH88 F1SJR4 F1SKH5 F1SKH7 F1SKR9 F1SMK2 F1SNI1 F1SNP7 F1SQW0 F1SRN4 F1SSN5 F1SUS7 I3L5H9 I3L837 I3LB11 I3LBU6 I3LCC0 I3LD06 I3LDR4 I3LIX0 I3LIY8 I3LJN3 I3LKJ5 I3LKY7 I3LKZ2 I3LPE0 I3LQ81 I3LQV1 I3LS68 M3VH35 M3VHA7 Q007T2 Q8HZV3 Q8WNW3	ABR ARAP1 ARAP2 ARAP3 ARFGAP2 ARFGAP3 ARHGAP1 ARHGAP10 ARHGAP17 ARHGAP20 ARHGAP21 ARHGAP22 ARHGAP24 ARHGAP26 ARHGAP27 ARHGAP29 ARHGAP30 ARHGAP31 ARHGAP33 ARHGAP35 ARHGAP39 ARHGAP4 ARHGAP44 ARHGAP45 ARHGAP5 ARHGAP9 ARHGDIA ARHGDIG ARHGEF10 ARHGEF11 ARHGEF12 ARHGEF15 ARHGEF16 ARHGEF19 ARHGEF25 ARHGEF26 ARHGEF5 ARHGEF6 ARHGEF7 ARHGEF9 BAIAP2 BCR CAV1 CDC42 CDC42BPA CDC42BPB CDC42EP1 CDC42EP2 CDC42EP3 CDC42EP4 CDC42EP5 CDC42SE2 CHN1 CPNE8 DAAM1 DEF6 DEPDC1B DIAPH3 DLC1 DNMBP DOCK10 DOCK11 DOCK6 DOCK7 DOCK8 DOCK9 ECT2 FAM13B FARP1 FGD1 FGD2 FGD3 FGD4 FMNL1 FMNL2 FMNL3 FNBP1 FNBP1L GIT1 GIT2 GMIP GNA13 GOLGA2 IQGAP2 IQGAP3 ITSN1 JUP Jup KCTD3 KTN1 LAMTOR1 LBR MAP3K11 MCF2 MCF2L MYO9B NGEF OPHN1 PAK1 PAK2 PAK5 PAK6 PARD6A PIK3R1 PIK3R2 PLD1 PLEKHG1 PLEKHG2 PLEKHG3 PREX1 PREX2 RAB7A RACGAP1 RASGRF2 SCRIB SH3PXD2A SHKBP1 SNAP23 SRGAP1 SRGAP2 SRGAP3 STARD8 STEAP3 STOM SYDE1 TAGAP TFRC TIAM1 TRIO VAMP3 VANGL1 VAV2 WASL WDR81 WDR91 WIPF1 YKT6	Sus scrofa (pig)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Asialoglycoprotein receptor 2 Glycosyltransferase 2-like domain-containing protein Uromodulin	A0A5G2Q826 A0A5G2QNB6 F1RPA9 I3L7N4	ASGR1 ASGR2 LOC110255214 UMOD	Sus scrofa (pig)
Response to elevated platelet cytosolic Ca2+	Protein kinase C Protein kinase C	F1RNJ0 F1RV14	PRKCA PRKCG	Sus scrofa (pig)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	CDK9 Cyclin K Cyclin T2 Cyclin-C Cyclin-T1 Cyclin-dependent kinase 8 E2F transcription factor 4 E2F transcription factor 5 Menin Mitogen-activated protein kinase Mitogen-activated protein kinase Mothers against decapentaplegic homolog 3 Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Polyubiquitin-C RB transcriptional corepressor like 1 RING-type E3 ubiquitin transferase Sp1 transcription factor Transcription factor Ubiquitin B Ubiquitin C Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein WW domain containing transcription regulator 1 furin	A0A286ZQB6 A0A286ZZJ6 A0A286ZZW3 A0A287A3Y0 A0A287AEE7 A0A287ALK4 A0A287AZA7 A0A287B504 A0A287BE69 A0A2C9F3G2 A0A480NH74 A0A5G2RG05 A0A8W4F719 A7U5U2 C9E1C9 F1CK19 F1RMJ1 F1RN38 F1RQR2 F1RXB8 F1S911 F1SAQ3 F1SJP0 P0CG68 P84024 Q9GKQ9	CCNC CCNK CCNT1 CCNT2 CDK8 CDK9 E2F4 E2F5 FURIN MADH3 MADH4 MAPK1 MAPK3 MEN1 RBL1 RNF111 RPS27A SMAD2 SMAD3 SMAD4 SMAD7 SP1 Smad7 TFDP1 UBA52 UBB UBC WWTR1	Sus scrofa (pig)
Ion homeostasis	ATPase Na+/K+ transporting subunit alpha 3 Adenosylhomocysteinase like 1 Aspartate beta-hydroxylase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium-transporting ATPase Calcium/calmodulin-dependent protein kinase type II subunit delta Calmodulin 3 Cardiac phospholamban FXYD domain-containing ion transport regulator Inositol 1,4,5-trisphosphate receptor Inositol 1,4,5-trisphosphate receptor Nitric oxide synthase 1 Phospholemman Ryanodine receptor 2 Ryanodine receptor 3 Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 Short transient receptor potential channel 1 Sodium/calcium exchanger 3 isoform X1 Sodium/potassium-transporting ATPase subunit alpha-2 Sodium/potassium-transporting ATPase subunit beta-1 Sodium/potassium-transporting ATPase subunit beta Sodium/potassium-transporting ATPase subunit beta Solute carrier family 8 member A2 Sorcin Stromal interaction molecule 1 Triadin calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase calcium/calmodulin-dependent protein kinase non-specific serine/threonine protein kinase peptidylprolyl isomerase	A0A286ZK85 A0A287AL21 A0A287APC7 A0A287AT82 A0A287B705 A0A287BAN5 A0A287BCC5 A0A287BE30 A0A287BKF3 A0A287BL11 A0A287BNT0 A0A5G2QCQ9 A0A5G2QQF7 A0A5G2QSI9 A0A5G2QWK6 A0A5G2R1W3 A0A5G2R3M0 A0A5G2RCE3 A0A5K1VCX5 A0A8W4FHV9 A0A8W4FK37 A0A8X9AEX2 D2WKD8 E7EI18 F1RL74 F1S340 F1S4A9 F1ST41 F2Z5F0 I3LMB3 O77696 P05027 P11607 P61013 Q95266	AHCYL1 ASPH ATP1A2 ATP1A3 ATP1B1 ATP1B2 ATP1B3 ATP2A1 ATP2A2 ATP2A3 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CALM3 CAMK2A CAMK2B CAMK2D CAMK2G DMPK FKBP1B FXYD1 FXYD6 ITPR1 ITPR3 NOS1 PLM PLN RYR2 RYR3 SLC8A2 SLC8A3 SRI STIM1 TRDN TRPC1	Sus scrofa (pig)
CASP8 activity is inhibited	Caspase 9 Caspase-8 FAS-associated death domain protein Receptor interacting serine/threonine kinase 1 TNF receptor-associated factor Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor superfamily member 6 Tumor necrosis factor receptor type 1-associated DEATH domain protein	A0A287BPE4 A0A287BRT1 F1RVZ4 F1SCY7 F1SUV9 O77736 Q56VC2 Q56VC3	APT1 CASP8 CASP9 FADD FAS RIPK1 TNFRSF6 TRADD TRAF2	Sus scrofa (pig)
Downstream TCR signaling	26S protease regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 8 26S proteasome non-ATPase regulatory subunit 9 26S proteasome regulatory subunit 8 3-phosphoinositide-dependent protein kinase 1 B-cell CLL/lymphoma 10 Caspase recruitment domain family member 11 Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein IkappaB kinase Inhibitor of nuclear factor kappa-B kinase subunit alpha MALT1 paracaspase MHC class II DR-alpha MHC class II antigen MHC class II histocompatibility antigen SLA-DRB1 Mitogen-activated protein kinase kinase kinase 7 NF-kappa-B essential modulator NF-kappa-B inhibitor alpha Nuclear factor NF-kappa-B p105 subunit Phosphatase and tensin homolog Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta Proteasome 20S subunit alpha 2 Proteasome 26S subunit, ATPase 3 Proteasome 26S subunit, ATPase 6 Proteasome 26S subunit, non-ATPase 14 Proteasome 26S subunit, non-ATPase 7 Proteasome activator complex subunit 1 Proteasome activator complex subunit 2 Proteasome activator complex subunit 3 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-7 Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta RELA proto-oncogene, NF-kB subunit Receptor-interacting serine/threonine-protein kinase 2 SLA class II histocompatibility antigen, DQ haplotype D alpha chain SLA-DQ beta1 domain T-cell surface glycoprotein CD3 delta chain T-cell surface glycoprotein CD3 epsilon chain T-cell surface glycoprotein CD3 gamma chain T-cell surface glycoprotein CD3 zeta chain T-cell surface glycoprotein CD4 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 TNF receptor-associated factor 6 Tyrosine-protein kinase UBC core domain-containing protein Uncharacterized protein Uncharacterized protein phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZKB7 A0A286ZLP7 A0A286ZN52 A0A286ZS34 A0A286ZUJ9 A0A286ZV67 A0A287A3X6 A0A287A5Q1 A0A287ABR0 A0A287AC24 A0A287AEH0 A0A287APQ3 A0A287AT33 A0A287AVR3 A0A287B5Q7 A0A287B968 A0A287BF11 A0A287BG14 A0A287BPP9 A0A287BQ31 A0A287BRR7 A0A287BRV0 A0A288CG47 A0A480JRT9 A0A5G2QCN4 A0A5G2QI19 A0A5G2QL81 A0A5G2QSU8 A0A5G2QZC6 A0A5G2R6X9 A0A5K1UB41 A0A8W4F9V5 A0A8W4FBN9 A0A8W4FHK5 A0A8W4FJW4 A0A8W4FNK4 A0A8W4FNV3 A0A8W4FP49 A0A8X9AEI7 A0A8X9AEU9 A1XQU1 A7XP20 A7XUJ6 A9QT41 B0LXP5 F1RKW8 F1RPQ3 F1RXA7 F1S6S1 F1S7S1 F1S8V5 F1S916 F1S975 F1S9C7 F1SBA5 F1SGF1 F1SGM3 F1SKR9 F1SMW9 F1SV94 F2Z5H1 F2Z5J1 F2Z5K2 F2Z5N0 F6PVF4 I3L556 I3LAQ5 K7GL70 K7GQH5 K7GS60 P15981 P61291 P62197 Q08353 Q2PYM7 Q5PXD3 Q64L94 Q764N2 Q7YQ94 Q85ZW4	BCL10 CARD11 CD247 CD3D CD3E CD3G CD4 CHUK DRA HLA-DRA IKBA IKBKB IKBKG INPP5D LCK LMP2 LOC100153139 MALT1 MAP3K7 NFKB1 NFKBIA PDPK1 PIK3CA PIK3CB PIK3R1 PIK3R2 PRORP PSMA1 PSMA2 PSMA4 PSMA5 PSMA6 PSMA7 PSMA8 PSMB1 PSMB10 PSMB11 PSMB3 PSMB7 PSMB9 PSMC1 PSMC3 PSMC5 PSMC6 PSMD1 PSMD11 PSMD13 PSMD14 PSMD2 PSMD3 PSMD4 PSMD6 PSMD7 PSMD8 PSMD9 PSME1 PSME2 PSME3 PSME4 PSMF1 PTEN RELA RIPK2 SLA-DQA SLA-DQA1 SLA-DQB1 SLA-DR SLA-DRA SLA-DRA1 SLA-DRB1 TAB2 TAK1b TRAF6 UBE2NL	Sus scrofa (pig)
Organic anion transport	Organic anion transporter 3 Solute carrier family 22 member 11 Solute carrier family 22 member 12 Solute carrier family 22 member 6 Solute carrier family 22 member 7	A0A8W4FD67 I3L7D2 I3LKR0 Q1RPP5 Q70BM6	OAT2 OAT3 SLC22A11 SLC22A12 SLC22A6 SLC22A7 SLC22A8	Sus scrofa (pig)
Apoptotic cleavage of cell adhesion proteins	Cadherin-1 Catenin beta-1 Desmoglein 1 Desmoglein 2 Desmoglein 3 Desmoglein-1 Desmoplakin Occludin Plakophilin 1 Tight junction protein 1 Tight junction protein 2	A0A287AL69 A0A287AQX9 A0A287ATF2 A0A287BF71 F1RW75 F6QAP1 I3L5Z1 I3LA65 I3LGN8 I3LU54 Q3BDI7	CDH1 CTNNB1 DSG1 DSG2 DSG3 DSP OCLN PKP1 TJP1 TJP2	Sus scrofa (pig)
Interleukin receptor SHC signaling	Colony stimulating factor 2 receptor subunit beta Fibronectin type-III domain-containing protein GRB2 associated binding protein 2 Granulocyte-macrophage colony-stimulating factor Growth factor receptor bound protein 2 Interleukin 2 receptor gamma Interleukin 5 receptor subunit alpha Interleukin-2 receptor subunit alpha Interleukin-2 receptor subunit beta Interleukin-2 Interleukin-5 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 Phosphatidylinositol 3-kinase regulatory subunit beta SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1 Tyrosine-protein kinase JAK2 Tyrosine-protein kinase Tyrosine-protein kinase phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A286ZLI2 A0A286ZUQ0 A0A287A7A4 A0A287ABR0 A0A287AFR0 A0A287B630 A0A287BFJ1 A0A5G2QEJ3 A0A5G2RAE7 A0A5K1UB41 A0A5K1UPW2 A0A5K1V5Y3 A0A8X9AEI7 B6E241 F1S916 F1SFL9 F1SKR9 K7GSE8 O19064 P26891 Q29118 Q76KD0 Q9MYM5	CSF2 CSF2RA CSF2RB GAB2 GRB2 IL2 IL2RA IL2RB IL2RG IL5 IL5RA INPP5D INPPL1 JAK1 JAK2 JAK3 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 SHC1 SOS1	Sus scrofa (pig)
Transport of organic anions	Monocarboxylate transporter 8 Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Solute carrier organic anion transporter family member Vasopressin-neurophysin 2-copeptin	A0A286ZS46 A0A287ASP2 A0A5G2QZU2 A0A5K1U410 A0A8W4FMT0 F1SQZ5 F1SUN1 I3LJG4 P01183 Q2QEH5	AVP SLC16A2 SLCO1A2 SLCO1B2 SLCO1B3 SLCO1C1 SLCO2A1 SLCO2B1 SLCO3A1 SLCO4A1 SLCO4C1	Sus scrofa (pig)
MET activates PTPN11	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Tyrosine-protein phosphatase non-receptor type	A0A480LMF4 B6E241 F1SB93 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PTPN11	Sus scrofa (pig)
Neurotransmitter clearance	Acetylcholinesterase Solute carrier family 22 member 1 Solute carrier family 22 member 2	A0A287A9U9 A0A5G2QVL5 O02713	ACHE OCT2 SLC22A1 SLC22A2	Sus scrofa (pig)
Glycerophospholipid catabolism	Glycerophosphocholine cholinephosphodiesterase ENPP6 Glycerophosphodiester phosphodiesterase 1 Patatin like phospholipase domain containing 6	A0A286ZW95 I3LLY2 Q58D68	ENPP6 GDE1 PNPLA6	Sus scrofa (pig)
Molecules associated with elastic fibres	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 7 (Osteogenic protein 1) EGF containing fibulin extracellular matrix protein 2 Fibulin-5 Growth differentiation factor 5 Integrin beta Integrin beta Integrin beta Integrin beta Integrin beta Integrin subunit alpha 8 Integrin subunit alpha V Latent transforming growth factor beta binding protein 1 Latent transforming growth factor beta binding protein 3 Latent transforming growth factor beta binding protein 4 Microfibril associated protein 2 Microfibril associated protein 4 Microfibril associated protein 5 Transforming growth factor beta-1 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta-3 proprotein Transforming growth factor beta Vitronectin	A0A286ZV08 A0A286ZWQ1 A0A286ZZE2 A0A287A7C6 A0A287AZ66 A0A287AZP0 A0A287BIH5 A0A287BIU2 A0A5G2QNS3 A0A5G2R2Y0 A0A5G2R7K7 A0A5K1V6L8 A0A8W4FF41 A5GFN2 A7LJT9 A9X6R3 F1RRJ9 F1RW86 F1S4W8 F1SD87 K7GQ83 K7GSJ9 P07200 P15203 P48819	BMP10 BMP2 BMP4 BMP7 EFEMP2 FBLN5 GDF5 ITGA8 ITGAV ITGB1 ITGB3 ITGB5 ITGB6 ITGB8 LTBP1 LTBP3 LTBP4 MFAP2 MFAP4 MFAP5 TGFB1 TGFB2 TGFB3 VTN bmp4	Sus scrofa (pig)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial Mitogen-activated protein kinase kinase kinase 1 TNF receptor-associated factor 6	A0A287ABQ5 A7XUJ6 F1SA28	ECSIT MAP3K1 TRAF6	Sus scrofa (pig)
Signaling by BMP	Bone morphogenetic protein 10 Bone morphogenetic protein 2 Cerberus Chordin like 1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase E3 ubiquitin-protein ligase Follistatin-related protein 1 Gremlin 2, DAN family BMP antagonist Growth differentiation factor 2 Inhibin alpha chain Inhibin beta A chain Mothers against decapentaplegic homolog 4 Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Mothers against decapentaplegic homolog Muellerian-inhibiting factor Noggin Serine/threonine-protein kinase receptor Serine/threonine-protein kinase receptor Ski oncogene Transforming growth factor beta receptor 3 Ubiquitin conjugating enzyme E2 D3 Zinc finger FYVE domain-containing protein 16 receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase receptor protein serine/threonine kinase	A0A286ZNF5 A0A286ZPH0 A0A286ZZE2 A0A287A7C6 A0A287AGC8 A0A287ATZ7 A0A287BJX6 A0A287BP22 A0A287BPI7 A0A287BPP8 A0A288CFV1 A0A5K1UKI8 A0A5K1VCW0 A0A8W4FLQ9 B8XVN4 E9M2M3 F1CK19 F1RF24 F1S0H6 F1S9G0 F1SEL6 F1SGK0 F1SI16 F1SJJ2 I3LTD6 K7GRE3 P03970 P04087 Q06AA8 Q864V7 Q9GKQ9	ACVR2A ACVR2B ACVRL1 AMH AMHR2 BMP10 BMP2 BMPR1A BMPR1B BMPR2 CER1 CHRDL1 FSTL1 GDF2 GREM2 INHA INHBA MADH1 MADH4 NOG SKI SMAD1 SMAD4 SMAD5 SMAD6 SMAD7 SMAD9 SMURF1 SMURF2 Smad7 TGFBR3 UBE2D1 UBE2D3 ZFYVE16	Sus scrofa (pig)
MET activates PI3K/AKT signaling	GRB2 associated binding protein 1 Growth factor receptor bound protein 2 Hepatocyte growth factor receptor Hepatocyte growth factor Phosphatidylinositol 3-kinase regulatory subunit alpha isoform 2 phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A5K1UB41 B6E241 F1SB93 F1SKR9 K7GMT0 Q2QLE0	GAB1 GRB2 HGF MET PIK3CA PIK3R1	Sus scrofa (pig)
Sema4D mediated inhibition of cell attachment and migration	Hepatocyte growth factor receptor Plexin B1 RAS related Ras-related C3 botulinum toxin substrate 1 Rho GTPase-activating protein 35 Semaphorin 4D Transforming protein RhoA	A0A5K1TV69 A0A8W4FI56 F1RHW4 F1RM07 F1SLI0 I3LVS7 Q2QLE0	ARHGAP35 MET PLXNB1 RAC1 RHOA RRAS SEMA4D	Sus scrofa (pig)

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