FCERI mediated MAPK activation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
MAPK8,9,10ADPATPp-MAPK8,9,10p-MAPK8,9,10JUNp-S63,S73-JUNADPATPFOSphosphorylated c-FOSp-2S-cJUN:p-2S,2T-cFOSp-5Y-LAT-2p-5Y-LAT:p-SHC1:GRB2:SOS1p-SHC1:GRB2:SOSp-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76GADS:SLP76PLC gamma1,2p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:SLP76:PLCGGTPp21 RAS:GTPGDPp21 RAS:GDPSHC1SHC1GRB2-1:SOS1p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCGVAV1,2,3p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAVp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAVRAC1:GDPp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTPPAK dimerp-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:PIP3:p-VAV:RAC1-GTP:PAK dimerp-2Y-PAKp-T1400,T1412-MEKK1MEKK1p-S257,T261-SEK1SEK1MKK7MAP2K7
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025