RMTs methylate histone arginines

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ATPJBP1ADPJBP1PRMT5:WDR77WDR77CCND1:CDK4:PRMT5:WDR77CCND1:CDK4:PRMT5:pT5-WDR77SAMSAHHistone H3MeR9-histone H3Me2sR9-histone H3CCND1:CDK4:PRMT5:pT5-WDR77:COPRSCOPRSMe2sR4-HIST1H4, MeR4-HIST1H4MeR4-HIST1H4, HIST1H4Histone H2AMe2sR4-histone H2AMe2sR3-histone H3RBBP7RBBP7:Replicative histone H3WDR5:Me2sR3-histone H3WDR5HIST1H4AMe2R4-HIST1H4:DNMT3ADNMT3APRMT5:pT5-WDR77SWI/SNF chromatin remodelling complex:PRMT5:pT5-WDR77SWI/SNF chromatin remodelling complexHIST1H4HIST1H4AHIST1H4AMeR18-histone H3, Histone H3Me2aR18-histone H3, MeR18-histone H3MeR27-histone H3, Histone H3Me2aR27-histone H3, MeR27-histone H3MeR3-histone H3, Histone H3Me2aR3-histone H3, MeR3-histone H3Me2aR4-histone H2A, MeR4-histone H2AMeR4-histone H2A, Histone H2AMeR12-histone H2A, Histone H2AMe2aR12-histone H2A, MeR12-histone H2AMeR30-histone H2A, Histone H2AMe2aR30-histone H2A, MeR30-histone H2ASAMSAHS4S4
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 27 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O14497 AT-rich interactive domain-containing protein 1A
  • ARID1A
  • BAF250
  • BAF250A
  • C1orf4
  • OSA1
  • SMARCF1
view
O14744 Protein arginine N-methyltransferase 5
  • HRMT1L5
  • IBP72
  • JBP1
  • PRMT5
  • SKB1
view
O96019 Actin-like protein 6A
  • ACTL6A
  • BAF53
  • BAF53A
  • INO80K
view
P04908 Histone H2A type 1-B/E
  • H2AC4
  • H2AC8
  • H2AFA
  • H2AFM
  • HIST1H2AB
  • HIST1H2AE
view
P0C0S8 Histone H2A type 1
  • H2AC11
  • H2AC13
  • H2AC15
  • H2AC16
  • H2AC17
  • H2AFC
  • H2AFD
  • H2AFI
  • H2AFN
  • H2AFP
  • HIST1H2AG
  • HIST1H2AI
  • HIST1H2AK
  • HIST1H2AL
  • HIST1H2AM
view
P15880 Small ribosomal subunit protein uS5
  • RPS2
  • RPS4
view
P16104 Histone H2AX
  • H2AFX
  • H2AX
view
P51531 Probable global transcription activator SNF2L2
  • BAF190B
  • BRM
  • SMARCA2
  • SNF2A
  • SNF2L2
view
P51532 Transcription activator BRG1
  • BAF190A
  • BRG1
  • SMARCA4
  • SNF2B
  • SNF2L4
view
P61964 WD repeat-containing protein 5
  • BIG3
  • WDR5
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025