Transcriptional regulation of pluripotent stem cells

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
EPAS1 geneEPAS1OCT4LIN28:OCT4 mRNALIN28OCT3SOX2 geneSOX2OCT4:SOX2:NANOG:SOX2 geneNANOGOCT4:SOX2:NANOG:ZSCAN10:PRDM14:SMAD2:SALL4:FOXP1-ES:OCT4 geneZNF206SALL4PRDM14FOXP1p-2S-SMAD2:p-2S-SMAD2:SMAD4OCT4 geneOCT4:SOX2:NANOG:KLF4:PBX1:SMAD2:FOXP1-ES:NANOG genePBX1KLF4NANOG geneSALL4 geneSALL4:SALL4 geneOCT4:STAT3:SALL4 gene2x(p-Y705-STAT3)
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 8 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O43474 Krueppel-like factor 4
  • EZF
  • GKLF
  • KLF4
view
P40763 Signal transducer and activator of transcription 3
  • APRF
  • STAT3
view
P48431 Transcription factor SOX-2
  • SOX2
view
Q01860 POU domain, class 5, transcription factor 1
  • OCT3
  • OCT4
  • OTF3
  • POU5F1
view
Q13485 Mothers against decapentaplegic homolog 4
  • DPC4
  • MADH4
  • SMAD4
view
Q99814 Endothelial PAS domain-containing protein 1
  • BHLHE73
  • EPAS1
  • HIF2A
  • MOP2
  • PASD2
view
Q9H9Z2 Protein lin-28 homolog A
  • CSDD1
  • LIN28
  • LIN28A
  • ZCCHC1
view
Q9UJQ4 Sal-like protein 4
  • SALL4
  • ZNF797
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025