Dual incision in TC-NER

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TC-NER pre-incision complexADPPiATPTC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNATC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNAERCC5TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNARPA heterotrimerTC-NER incision complexERCC1:ERCC4TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNARFC HeteropentamerTC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFCPCNA homotrimer,MonoUb:K164-PCNA homotrimerPOLD,POLE,POLKXPATC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025