Interleukin-37 signaling

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Caspase-1 tetramerIL37:2x(CASP1(120-197):CASP1(317-404))IL37IL37(1-?):IL37(?-218):CASP1(120-197):CASP1(317-404)IL37(1-?)IL37(?-218)IL37(?-218)IL37(?-218):p-S423,S425-SMAD3p-2S-SMAD3IL37(?-218):p-S423,S425-SMAD3PTPN genes2,4,5,6,7,9,11,12,13,14,18,20,23PTPNs2,4,5,6,7,9,11,12,13,14,18,20,23IL37(?-218):SMAD3SMAD3IL37,IL37(?-218)IL37,IL37(?-218)IL18BPIL18BP:IL37,IL37(?-218)IL18R1IL18R1:IL37,IL37(?-218)SIGRRIL18R1:IL37,IL37(?-218):SIGIRRATPp-TBK1TBK1ADPp-Y705-STAT3STAT3
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025