FOXO-mediated transcription of cell cycle genes

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
PCBP4PCBP4:CDKN1A mRNAp21 mRNAp21FOXO1,FOXO3,FOXO4FOXO1,FOXO3,FOXO4:CDKN1A genep21 geneFOXO1,FOXO3,FOXO4:p-2S-SMAD2/3:SMAD4p-2S-SMAD2,3:SMAD4FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4:CDKN1A geneFOXG1:FOXO3,(FOXO1,FOXO4):p-2S-SMAD2/3:SMAD4FOXG1CDKN1B geneglnAFOXO3,FOXO4,(FOXO1)FOXO3,FOXO4,(FOXO1):GADD45A geneGADD45A geneDDIT1FOXO1,FOXO3,FOXO4:RBL2 geneRBL2 geneRBL2FOXO1,FOXO3,(FOXO4)FOXO1,FOXO3,(FOXO4):CCNG2 geneCCNG2 geneCCNG2BTG1 geneFOXO3:BTG1 geneFOXO3BTG1CAV1 geneFOXO1,FOXO3:CAV1 geneFOXO1,FOXO3CAV1KLF4 geneFOXO1,FOXO3:KLF4 geneKLF4MSTN geneFOXO1:p-2S-SMAD2/3:SMAD4:MSTN geneFOXO1Myostatin
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 9 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O14793 Growth/differentiation factor 8
  • GDF8
  • MSTN
view
O43474 Krueppel-like factor 4
  • EZF
  • GKLF
  • KLF4
view
O43524 Forkhead box protein O3
  • FKHRL1
  • FOXO3
  • FOXO3A
view
P46527 Cyclin-dependent kinase inhibitor 1B
  • CDKN1B
  • KIP1
  • p27
view
P57723 Poly(rC)-binding protein 4
  • PCBP4
view
P98177 Forkhead box protein O4
  • AFX
  • AFX1
  • FOXO4
  • MLLT7
view
Q08999 Retinoblastoma-like protein 2
  • RB2
  • RBL2
view
Q12778 Forkhead box protein O1
  • FKHR
  • FOXO1
  • FOXO1A
view
Q13485 Mothers against decapentaplegic homolog 4
  • DPC4
  • MADH4
  • SMAD4
view
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025