idiopathic pulmonary fibrosis

Summary
Synonym
  • FIBROCYSTIC PULMONARY DYSPLASIA
  • IDIOPATHIC PULMONARY FIBROSIS, FAMILIAL
  • cryptogenic fibrosing alveolitis
Definition
A pulmonary fibrosis that is characterized by scarring of the lung.
Super Class
pulmonary fibrosis
Disease Ontology
DOID:0050156
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
142 PARP1 poly(ADP-ribose) polymerase 1
207 AKT1 AKT serine/threonine kinase 1
335 APOA1 apolipoprotein A1
780 DDR1 discoidin domain receptor tyrosine kinase 1
2033 EP300 E1A binding protein p300
2152 F3 coagulation factor III, tissue factor
2263 FGFR2 fibroblast growth factor receptor 2
2355 FOSL2 FOS like 2, AP-1 transcription factor subunit
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3559 IL2RA interleukin 2 receptor subunit alpha
Displaying entries 11 - 20 of 20 in total
Gene ID Gene Symbol Description Source
18212 Ntrk2 neurotrophic tyrosine kinase, receptor, type 2
19225 Ptgs2 prostaglandin-endoperoxide synthase 2
20848 Stat3 signal transducer and activator of transcription 3
21788 Tfpi tissue factor pathway inhibitor
21824 Thbd thrombomodulin
21926 Tnf tumor necrosis factor
74180 Muc5b mucin 5, subtype B, tracheobronchial
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
235626 Setd2 SET domain containing 2
328572 Ep300 E1A binding protein p300
Displaying all 10 entries
Gene ID Gene Symbol Description Source
24185 Akt1 AKT serine/threonine kinase 1
24773 Sftpa1 surfactant protein A1
24835 Tnf tumor necrosis factor
25022 Fgfr2 fibroblast growth factor receptor 2
25054 Ntrk2 neurotrophic receptor tyrosine kinase 2
25556 Il1rl1 interleukin 1 receptor-like 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25704 Il2ra interleukin 2 receptor subunit alpha
29436 Tfpi tissue factor pathway inhibitor
29527 Ptgs2 prostaglandin-endoperoxide synthase 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
31722 fs(1)h female sterile (1) homeotic
39564 btl breathless
42160 htl heartless
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source
352940 fgfr2 fibroblast growth factor receptor 2
560788 parp1 poly (ADP-ribose) polymerase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
399170 akt1.S AKT serine/threonine kinase 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 4 entries
Gene ID Gene Symbol Description Source
178748 zmp-3 Matrix metalloproteinase-C
180622 ddr-2 Discoidin domain-containing receptor tyrosine kinase B
180836 W01C8.5 DM13 domain-containing protein
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
The Human Phenotype Ontology
Displaying entries 11 - 17 of 17 in total
HPO ID HPO Term
HP:0002875 Exertional dyspnea
HP:0010702 Increased circulating antibody level
HP:0002094 Dyspnea
HP:0000006 Autosomal dominant inheritance
HP:0001394 Cirrhosis
HP:0006519 Alveolar cell carcinoma
HP:0002092 Pulmonary arterial hypertension
Displaying all 3 entries
Gene ID Gene Symbol Description
6440 SFTPC surfactant protein C
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2

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Last updated: December 9, 2024