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idiopathic pulmonary fibrosis
Summary
- Synonym
-
- FIBROCYSTIC PULMONARY DYSPLASIA
- IDIOPATHIC PULMONARY FIBROSIS, FAMILIAL
- cryptogenic fibrosing alveolitis
- Definition
- A pulmonary fibrosis that is characterized by scarring of the lung characterized by stiffness in the lungs and makes it difficult to breathe.
- Super Class
- autosomal dominant disease pulmonary fibrosis
External Links
- Disease Ontology
- DOID:0050156
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- GARD
- MGI genotype (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 5743 | PTGS2 | prostaglandin-endoperoxide synthase 2 | |
| 7015 | TERT | telomerase reverse transcriptase | |
| 10919 | EHMT2 | euchromatic histone lysine methyltransferase 2 | |
| 23476 | BRD4 | bromodomain containing 4 | |
| 29072 | SETD2 | SET domain containing 2, histone lysine methyltransferase | |
| 727897 | MUC5B | mucin 5B, oligomeric mucus/gel-forming | |
| 729238 | SFTPA2 | surfactant protein A2 |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P06804 | Tumor necrosis factor | |
| P47930 | Fos-related antigen 2 |
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q63474 | Epithelial discoidin domain-containing receptor 1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0006530 | Abnormal pulmonary interstitial morphology |
| HP:0002094 | Dyspnea |
| HP:0010702 | Increased circulating antibody level |
| HP:0001394 | Cirrhosis |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0006519 | Alveolar cell carcinoma |
| HP:0002092 | Pulmonary arterial hypertension |
