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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
primary progressive multiple sclerosis
Summary
- Synonym
-
- PPMS
- Primary-progressive MS
- Definition
- A multiple sclerosis that is characterized by steady worsening of neurologic functioning, without any distinct relapses or periods of remission. The rate of progression may vary over time, with occasional plateaus or temporary improvements, but the progression is continuous.
- Super Class
- multiple sclerosis
External Links
- Disease Ontology
- DOID:0050784
- Mondo Disease Ontology
- MeSH
- UMLS
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 590 | BCHE | butyrylcholinesterase | |
| 2638 | GC | GC vitamin D binding protein | |
| 2896 | GRN | granulin precursor | |
| 3119 | HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 | |
| 3123 | HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | |
| 3486 | IGFBP3 | insulin like growth factor binding protein 3 | |
| 3566 | IL4R | interleukin 4 receptor | |
| 4318 | MMP9 | matrix metallopeptidase 9 | |
| 6469 | SHH | sonic hedgehog signaling molecule | |
| 140766 | ADAMTS14 | ADAM metallopeptidase with thrombospondin type 1 motif 14 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 12038 | Bche | butyrylcholinesterase | |
| 14473 | Gc | vitamin D binding protein | |
| 14824 | Grn | granulin | |
| 14961 | H2-Ab1 | histocompatibility 2, class II antigen A, beta 1 | |
| 14969 | H2-Eb1 | histocompatibility 2, class II antigen E beta | |
| 16009 | Igfbp3 | insulin-like growth factor binding protein 3 | |
| 16190 | Il4ra | interleukin 4 receptor, alpha | |
| 17395 | Mmp9 | matrix metallopeptidase 9 | |
| 20423 | Shh | sonic hedgehog |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 171905 | ace-2 | Carboxylic ester hydrolase | |
| 175076 | ace-3 | Carboxylic ester hydrolase | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180349 | grd-2 | Ground-like domain-containing protein | |
| 180351 | W01F3.2 | Uncharacterized protein | |
| 180638 | wrt-6 | Warthog protein 6 N-product | |
| 181706 | ace-1 | Acetylcholinesterase 1 |
