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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
interleukin 4 receptor
Summary
- Gene Symbol
-
- IL4R
- Organism
- Homo sapiens (human)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| T-helper 1 cell differentiation | ||
| positive regulation of mast cell degranulation | ||
| positive regulation of chemokine production | ||
| positive regulation of T-helper 2 cell differentiation | ||
| defense response to protozoan |
GO Hierarchy
biological process
immune system process [inference]
cellular process [inference]
multicellular organismal process [inference]
developmental process [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
negative regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of lymphocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
regulation of hemopoiesis [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of developmental process [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
negative regulation of immune system process [inference]
negative regulation of cellular process [inference]
negative regulation of developmental process [inference]
negative regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of developmental process [inference]
regulation of cell differentiation [inference]
regulation of cell development [inference]
regulation of hemopoiesis [inference]
negative regulation of developmental process [inference]
positive regulation of developmental process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
regulation of cellular process [inference]
regulation of cell adhesion [inference]
regulation of cellular metabolic process [inference]
regulation of cell differentiation [inference]
regulation of cell development [inference]
regulation of hemopoiesis [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cell activation [inference]
regulation of leukocyte activation [inference]
negative regulation of leukocyte activation [inference]
positive regulation of leukocyte activation [inference]
regulation of lymphocyte activation [inference]
regulation of lymphocyte differentiation [inference]
regulation of T cell activation [inference]
regulation of T cell differentiation [inference]
regulation of alpha-beta T cell activation [inference]
negative regulation of lymphocyte activation [inference]
negative regulation of cell activation [inference]
positive regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of multicellular organismal process [inference]
regulation of multicellular organismal development [inference]
regulation of hemopoiesis [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| external side of plasma membrane | ||
| centriolar satellite | ||
| receptor complex | ||
| plasma membrane | ||
| extracellular region |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| cytokine receptor activity | ||
| interleukin-4 receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- interleukin-4 receptor subunit alpha
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- L: Replication, recombination and repair
| Gene Ontology |
|---|
| cytokine-mediated signaling pathway |
| production of molecular mediator involved in inflammatory response |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050784 | primary progressive multiple sclerosis | |
| DOID:11204 | allergic conjunctivitis | |
| DOID:11963 | esophagitis | |
| DOID:1793 | pancreatic cancer | |
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:2957 | pulmonary tuberculosis | |
| DOID:3082 | interstitial lung disease | |
| DOID:3261 | hyper IgE recurrent infection syndrome 1 | |
| DOID:3310 | atopic dermatitis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 16190 | MGI:105367 | MOUSE57007 | ||
| 25084 | RGD:2899 | RATNO16182 | ||
| 397614 | PIGXX20712 | |||
| 454005 | 9598_0:004087 | PANTR12016 | ||
| 489957 | CANLF16455 | |||
| 503594 | ZFIN:ZDB-GENE-050227-5 | |||
| 705404 | MACMU26927 | |||
| 100412639 | CALJA07589 | |||
| 100449812 | 9601_0:003db3 | PONAB10138 | ||
| 100476095 | AILME02488 |
