celiac disease

Summary
Synonym
  • celiac sprue
  • coeliac disease
  • idiopathic steatorrhea
Definition
An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.
Super Class
autoimmune disease of gastrointestinal tract
Disease Ontology
DOID:10608
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
GARD
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
929 CD14 CD14 molecule
1493 CTLA4 cytotoxic T-lymphocyte associated protein 4
2147 F2 coagulation factor II, thrombin
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3569 IL6 interleukin 6
29851 ICOS inducible T cell costimulator
149233 IL23R interleukin 23 receptor

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025