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MIRAGE
Cytotoxic T-lymphocyte protein 4
Summary
- UniProt ID
- P16410
- Gene Symbol
-
- CD152
- CTLA4
- Gene ID
- 1493
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Diabetes mellitus
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Pharmaceutical
- Phosphoprotein
- Reference proteome
- Signal
- Systemic lupus erythematosus
- Transmembrane helix
- Gene Ontology (GO)
Sequence
MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CTLA4 inhibitory signaling | Homo sapiens |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060025 | immunoglobulin alpha deficiency | |
| DOID:0060060 | non-Hodgkin lymphoma | |
| DOID:0080162 | lupus nephritis | |
| DOID:0080846 | latent autoimmune diabetes in adults | |
| DOID:0081120 | Graves ophthalmopathy | |
| DOID:0081267 | graft-versus-host disease | |
| DOID:0110751 | type 1 diabetes mellitus 12 | |
| DOID:10608 | celiac disease | |
| DOID:11335 | sarcoidosis | |
| DOID:12132 | granulomatosis with polyangiitis |
