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MIRAGE
Cytotoxic T-lymphocyte protein 4
Summary
- UniProt ID
- P16410
- Gene Symbol
-
- CD152
- CTLA4
- Gene ID
- 1493
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Adaptive immunity
- Alternative splicing
- Cell membrane
- Diabetes mellitus
- Disease variant
- Disulfide bond
- Glycoprotein
- Immunoglobulin domain
- Pharmaceutical
- Phosphoprotein
- Reference proteome
- Signal
- Systemic lupus erythematosus
- Transmembrane helix
- Gene Ontology (GO)
Sequence
MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| CTLA4 inhibitory signaling | Homo sapiens |
| RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs) | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:612 | primary immunodeficiency disease | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:718 | autoimmune hemolytic anemia | |
| DOID:7188 | autoimmune thyroiditis | |
| DOID:7442 | monoclonal gammopathy of uncertain significance | |
| DOID:783 | end stage renal disease | |
| DOID:8893 | psoriasis | |
| DOID:9074 | systemic lupus erythematosus | |
| DOID:9119 | acute myeloid leukemia | |
| DOID:9383 | iridocyclitis |
