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MIRAGE
Interleukin-23 receptor

Summary
UniProt ID
Q5VWK5
Gene Symbol
  • IL23R
Gene ID
149233
Organism
Homo sapiens (human)
GlyGen
Q5VWK5
PubChem
Q5VWK5
Re-Glyco
Q5VWK5
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cell membrane
  • Glycoprotein
  • Inflammatory response
  • Innate immunity
  • Phosphoprotein
  • Receptor
  • Reference proteome
  • Repeat
  • Signal
  • Transmembrane helix
Gene Ontology (GO)
Displaying all 5 entries
GO Term
plasma membrane
receptor complex
external side of plasma membrane
cell surface
interleukin-23 receptor complex
Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying all 2 entries
GO Term
cytokine receptor activity
cytokine binding
Annotation information from UniProt.
Sequence
MNQVTIQWDAVIALYILFSWCHGGITNINCSGHIWVEPATIFKMGMNISIYCQAAIKNCQPRKLHFYKNGIKERFQITRINKTTARLWYKNFLEPHASMYCTAECPKHFQETLICGKDISSGYPPDIPDEVTCVIYEYSGNMTCTWNAGKLTYIDTKYVVHVKSLETEEEQQYLTSSYINISTDSLQGGKKYLVWVQAANALGMEESKQLQIHLDDIVIPSAAVISRAETINATVPKTIIYWDSQTTIEKVSCEMRYKATTNQTWNVKEFDTNFTYVQQSEFYLEPNIKYVFQVRCQETGKRYWQPWSSLFFHKTPETVPQVTSKAFQHDTWNSGLTVASISTGHLTSDNRGDIGLLLGMIVFAVMLSILSLIGIFNRSFRTGIKRRILLLIPKWLYEDIPNMKNSNVVKMLQENSELMNNNSSEQVLYVDPMITEIKEIFIPEHKPTDYKKENTGPLETRDYPQNSLFDNTTVVYIPDLNTGYKPQISNFLPEGSHLSNNNEITSLTLKPPVDSLDSGNNPRLQKHPNFAFSVSSVNSLSNTIFLGELSLILNQGECSSPDIQNSVEEETTMLLENDSPSETIPEQTLLPDEFVSCLGIVNEELPSINTYFPQNILESHFNRISLLEK
  • N : N-glycosylation Site
  • ___ : Potential Sequon
Glycosylation Sites
Displaying all 9 entries
Position Description PubMed ID GlyTouCan ID Source
29 N-linked (GlcNAc...) asparagine; partial
47 N-linked (GlcNAc...) asparagine
58
81 N-linked (GlcNAc...) asparagine
141 N-linked (GlcNAc...) asparagine
180 N-linked (GlcNAc...) (high mannose) asparagine
232 N-linked (GlcNAc...) asparagine
262 N-linked (GlcNAc...) asparagine
273 N-linked (GlcNAc...) asparagine; partial
Feature
  • ProtVista GlyGen : Glycosylation Site from GlyGen
  • ProtVista UniProt : Glycosylation Site from UniProt
Pathway
Displaying all 2 entries
Pathway Name Organism
Interleukin-23 signaling Homo sapiens
Interleukin-4 and Interleukin-13 signaling Homo sapiens
Disease
Displaying entries 1 - 10 of 19 in total
DO ID Disease Name Source
DOID:0081120 Graves ophthalmopathy
DOID:0110883 inflammatory bowel disease 17
DOID:0111279 psoriasis 7
DOID:10159 osteonecrosis
DOID:10608 celiac disease
DOID:11335 sarcoidosis
DOID:12361 Graves' disease
DOID:13141 uveitis
DOID:13241 Behcet's disease
DOID:2377 multiple sclerosis
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International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 4, 2025