Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
Resources Genes Glycoproteins Lectins Glycolipids Glycans Pathways Diseases Organisms
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Other Information
Release Statistics Download
Tools
SugarDrawer GlycanBuilder Glycan Converters GlycoMaple GlycomeAtlas LM-GlycomeAtlas GALAXY MCAW GlycoSim GRable
Search Tools
Cross Search Glycan Search Publication Search Programmatic Access
Standards Ontologies Notations
Alzheimer's disease

Summary
Synonym
  • Alzheimer disease
  • Alzheimers dementia
Definition
A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid.
Super Class
tauopathy
External Links
Disease Ontology
DOID:10652
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 111 - 120 of 350 in total
Gene ID Gene Symbol Description Source
3339 HSPG2 heparan sulfate proteoglycan 2
3356 HTR2A 5-hydroxytryptamine receptor 2A
3383 ICAM1 intercellular adhesion molecule 1
3417 IDH1 isocitrate dehydrogenase (NADP(+)) 1
3418 IDH2 isocitrate dehydrogenase (NADP(+)) 2
3425 IDUA alpha-L-iduronidase
3481 IGF2 insulin like growth factor 2
3482 IGF2R insulin like growth factor 2 receptor
3554 IL1R1 interleukin 1 receptor type 1
3556 IL1RAP interleukin 1 receptor accessory protein
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
26416 Mapk14 mitogen-activated protein kinase 14
56637 Gsk3b glycogen synthase kinase 3 beta
68214 Gsto2 glutathione S-transferase omega 2
433182 Eno1b enolase 1B, retrotransposed
Displaying entries 1 - 10 of 19 in total
Gene ID Gene Symbol Description Source
24333 Eno1 enolase 1
24383 Gapdh glyceraldehyde-3-phosphate dehydrogenase
24483 Igf2 insulin-like growth factor 2
24505 Ins1 insulin 1
24506 Ins2 insulin 2
24835 Tnf tumor necrosis factor
25239 Apod apolipoprotein D
25513 Pik3r1 phosphoinositide-3-kinase regulatory subunit 1
25591 Parp1 poly (ADP-ribose) polymerase 1
25608 Lep leptin
Displaying all 9 entries
Gene ID Gene Symbol Description Source
31248 sgg shaggy
31293 N Notch
32545 Gapdh2 Glyceraldehyde 3 phosphate dehydrogenase 2
33351 Eno Enolase
35728 Gapdh1 Glyceraldehyde 3 phosphate dehydrogenase 1
37131 Pepck1 Phosphoenolpyruvate carboxykinase 1
38973 se sepia
43222 Tl Toll
3355109 Parp1 Poly-(ADP-ribose) polymerase 1
Displaying all 4 entries
Gene ID Gene Symbol Description Source
30262 ins preproinsulin
317743 gapdh glyceraldehyde-3-phosphate dehydrogenase
406367 gapdhs glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
560788 parp1 poly (ADP-ribose) polymerase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
380259 gapdh.S glyceraldehyde-3-phosphate dehydrogenase S homeolog Xenopus laevis (African clawed frog)
380298 eno1.S enolase 1 S homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
174423 enol-1 Enolase
174578 gpd-4 Glyceraldehyde-3-phosphate dehydrogenase 4
174603 gpd-1 Glyceraldehyde-3-phosphate dehydrogenase 1
180601 gpd-3 Glyceraldehyde-3-phosphate dehydrogenase 3
183000 gsto-1 Glutathione transferase omega-1
266823 parp-1 Poly [ADP-ribose] polymerase;Poly [ADP-ribose] polymerase 1
Displaying all 9 entries
Gene ID Gene Symbol Description Source
850666 GTT2 glutathione transferase GTT2
853106 TDH3 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH3
853169 ENO1 phosphopyruvate hydratase ENO1
853395 TDH1 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH1
853465 TDH2 glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) TDH2
854575 ERR1 phosphopyruvate hydratase ERR1
855373 ERR3 phosphopyruvate hydratase ERR3
855848 ERR2 phosphopyruvate hydratase ERR2
856579 ENO2 phosphopyruvate hydratase ENO2
Related Glycoprotein
About Release Notes Help Feedback

Click here to visit the beta site.

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

Logo License Policies Site Map

Contact: support@glycosmos.org

This work is licensed under Creative Commons Attribution 4.0 International

GlyCosmos Portal v4.0.0

Last updated: August 19, 2024