adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 31 - 38 of 38 in total
Gene ID Gene Symbol Description Source
7056 THBD thrombomodulin
7124 TNF tumor necrosis factor
7132 TNFRSF1A TNF receptor superfamily member 1A
7133 TNFRSF1B TNF receptor superfamily member 1B
10266 RAMP2 receptor activity modifying protein 2
10630 PDPN podoplanin
11035 RIPK3 receptor interacting serine/threonine kinase 3
653509 SFTPA1 surfactant protein A1
Displaying entries 11 - 20 of 36 in total
Gene ID Gene Symbol Description Source
16168 Il15 interleukin 15
16181 Il1rn interleukin 1 receptor antagonist
16198 Il9 interleukin 9
16625 Serpina3c serine (or cysteine) peptidase inhibitor, clade A, member 3C
16846 Lep leptin
16992 Lta lymphotoxin A
17195 Mbl2 mannose-binding lectin (protein C) 2
17395 Mmp9 matrix metallopeptidase 9
17829 Muc1 mucin 1, transmembrane
20388 Sftpb surfactant associated protein B
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
84007 C3ar1 complement C3a receptor 1
113959 C5ar1 complement C5a receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
192155 Sftpb surfactant protein B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024