adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 31 - 38 of 38 in total
Gene ID Gene Symbol Description Source
7056 THBD thrombomodulin
7124 TNF tumor necrosis factor
7132 TNFRSF1A TNF receptor superfamily member 1A
7133 TNFRSF1B TNF receptor superfamily member 1B
10266 RAMP2 receptor activity modifying protein 2
10630 PDPN podoplanin
11035 RIPK3 receptor interacting serine/threonine kinase 3
653509 SFTPA1 surfactant protein A1
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11596 Ager advanced glycosylation end product-specific receptor
11699 Ambp alpha 1 microglobulin/bikunin precursor
12266 C3 complement component 3
12267 C3ar1 complement component 3a receptor 1
12273 C5ar1 complement component 5a receptor 1
14066 F3 coagulation factor III
14726 Pdpn podoplanin
15139 Hc hemolytic complement
15894 Icam1 intercellular adhesion molecule 1
16153 Il10 interleukin 10
Displaying entries 11 - 20 of 24 in total
Gene ID Gene Symbol Description Source
25350 Sftpd surfactant protein D
25377 Ambp alpha-1-microglobulin/bikunin precursor
25464 Icam1 intercellular adhesion molecule 1
25608 Lep leptin
25625 Tnfrsf1a TNF receptor superfamily member 1A
25670 Il15 interleukin 15
54320 Pdpn podoplanin
58966 Ramp2 receptor activity modifying protein 2
60582 Il1rn interleukin 1 receptor antagonist
81687 Mmp9 matrix metallopeptidase 9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024