iron deficiency anemia

Summary
Definition
A nutritional deficiency disease that is characterized by pallor, fatigue, lightheadedness, and weakness and has_material_basis_in low total body iron causing impaired synthesis of red blood cells.
Super Class
nutritional deficiency disease
Disease Ontology
DOID:11758
UMLS
Related Genes
Displaying entries 1 - 10 of 17 in total
Gene ID Gene Symbol Description Source
351 APP amyloid beta precursor protein
538 ATP7A ATPase copper transporting alpha
712 C1QA complement C1q A chain
2335 FN1 fibronectin 1
2876 GPX1 glutathione peroxidase 1
3077 HFE homeostatic iron regulator
3240 HP haptoglobin
3569 IL6 interleukin 6
3658 IREB2 iron responsive element binding protein 2
3673 ITGA2 integrin subunit alpha 2
Displaying entries 11 - 17 of 17 in total
Gene ID Gene Symbol Description Source
18174 Slc11a2 solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
18979 Pon1 paraoxonase 1
20533 Slc4a1 solute carrier family 4 (anion exchanger), member 1
21926 Tnf tumor necrosis factor
22041 Trf transferrin
22042 Tfrc transferrin receptor
53945 Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
24464 Hp haptoglobin
24779 Slc4a1 solute carrier family 4 member 1 (Diego blood group)
24825 Tf transferrin
24835 Tnf tumor necrosis factor
24941 Atp7a ATPase copper transporting alpha
25307 Cst3 cystatin C
25419 Crp C-reactive protein
25715 Slc11a2 solute carrier family 11 member 2
29199 Hfe homeostatic iron regulator
54226 App amyloid beta precursor protein
Displaying all 4 entries
Gene ID Gene Symbol Description Source
31002 Appl beta amyloid protein precursor-like
36692 scb scab
39435 Tsf2 Transferrin 2
42490 Mvl Malvolio
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
Displaying all 9 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
177044 smf-3 NRAMP-like transporter smf-3
177372 cpi-1 Cystatin cpi-1
180783 apl-1 Amyloid-beta-like protein
180939 smf-1 NRAMP-like transporter smf-1
180943 abts-4 Anion exchange protein
181178 gpx-5 Glutathione peroxidase
182513 gpx-3 Glutathione peroxidase 3
187297 poml-1 PON (paraoxonase) and MEC-6 Like
Displaying all 5 entries
Gene ID Gene Symbol Description Source
850721 SMF3 putative divalent metal ion transporter SMF3
853590 VPS70 putative zinc metalloprotease
854430 TRE2 putative zinc metalloprotease
855927 TRE1 Tre1p
856014 GLR1 glutathione-disulfide reductase GLR1

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024