Pick's disease

Summary
Synonym
  • Dementia in Pick's disease
  • LOBAR ATROPHY OF BRAIN
  • PICK DISEASE OF BRAIN
  • Pick disease
Definition
A frontotemporal dementia that is characterized by a spectrum of neuropsychiatric symptoms ranging from those that affect the patient's personality to those that cause a decline in cognitive function.
Super Class
frontotemporal dementia
Disease Ontology
DOID:11870
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
MGI genotype (from TogoID)
Related Genes
Displaying all 2 entries
Gene ID Gene Symbol Description Source
4137 MAPT microtubule associated protein tau
5608 MAP2K6 mitogen-activated protein kinase kinase 6
The Human Phenotype Ontology
Displaying entries 41 - 50 of 50 in total
HPO ID HPO Term
HP:0001288 Gait disturbance
HP:0000741 Apathy
HP:0010529 Echolalia
HP:0000709 Psychosis
HP:0000723 Restrictive behavior
HP:0000734 Disinhibition
HP:0000737 Irritability
HP:0000710 Hyperorality
HP:0000719 Inappropriate behavior
HP:0012671 Abulia
Displaying 1 entry
Gene ID Gene Symbol Description
7415 VCP valosin containing protein

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 4, 2025