Chagas disease

Summary
Synonym
  • Chagas' disease
  • chagas' disease with digestive system involvement
  • chagas' disease with nervous system involvement
  • chagas' disease with other organ involvement
Definition
A trypanosomiasis that is a tropical parasitic disease caused by the flagellate protozoan Trypanosoma cruzi, which is transmitted to humans and other mammals by an insect vector, the blood-sucking assassin bugs of the subfamily Triatominae (family Reduviidae), most commonly species belonging to the Triatoma, Rhodnius, and Panstrongylus genera. The symptoms include fever, fatigue, body aches, headache, rash, loss of appetite, diarrhea, vomiting, swelling of the eyelids and myocarditis.
Super Class
trypanosomiasis
External Links
Disease Ontology
DOID:12140
Mondo Disease Ontology
MeSH
UMLS
ORDO
GARD
Related Genes
Displaying entries 11 - 20 of 35 in total
Gene ID Gene Symbol Description Source
2224 FDPS farnesyl diphosphate synthase
2539 G6PD glucose-6-phosphate dehydrogenase
2645 GCK glucokinase
2752 GLUL glutamate-ammonia ligase
3958 LGALS3 galectin 3
3965 LGALS9 galectin 9
4153 MBL2 mannose binding lectin 2
4860 PNP purine nucleoside phosphorylase
4907 NT5E 5'-nucleotidase ecto
5290 PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024