angle-closure glaucoma

Summary
Synonym
  • ACG - Angle-closure glaucoma
  • Angle Closure Glaucoma
  • Closed angle glaucoma
  • Narrow cleft glaucoma
  • primary open-angle glaucoma with narrow angles
Definition
A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.
Super Class
glaucoma
Disease Ontology
DOID:13550
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 5 entries
Gene ID Gene Symbol Description Source
348 APOE apolipoprotein E
847 CAT catalase
3082 HGF hepatocyte growth factor
4318 MMP9 matrix metallopeptidase 9
4846 NOS3 nitric oxide synthase 3
Displaying 1 entry
Gene ID Gene Symbol Description Source
21419 Tfap2b transcription factor AP-2 beta

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025