angle-closure glaucoma

Summary
Synonym
  • ACG - Angle-closure glaucoma
  • Angle Closure Glaucoma
  • Closed angle glaucoma
  • Narrow cleft glaucoma
  • primary open-angle glaucoma with narrow angles
Definition
A glaucoma characterized by closure of the anterior chamber angle such that aqueous outflow is blocked and the intraocular pressure becomes inappropriately elevated leading to optic nerve damage and visual field loss. Angle-closure glaucoma has_symptom progressive peripheral vision loss, decreased vision, and pain, redness, and headache in acute cases. Angle closure glaucoma can be caused by anatomically narrow angle, injury to the trabecular meshwork, and injuries to the anterior chamber, such as neovascularization and uveitis.
Super Class
glaucoma
Disease Ontology
DOID:13550
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 9 entries
Gene ID Gene Symbol Description Source
348 APOE apolipoprotein E
847 CAT catalase
1906 EDN1 endothelin 1
3082 HGF hepatocyte growth factor
4016 LOXL1 lysyl oxidase like 1
4318 MMP9 matrix metallopeptidase 9
4586 MUC5AC mucin 5AC, oligomeric mucus/gel-forming
4846 NOS3 nitric oxide synthase 3
7021 TFAP2B transcription factor AP-2 beta
Displaying all 5 entries
Gene ID Gene Symbol Description Source
15234 Hgf hepatocyte growth factor
17395 Mmp9 matrix metallopeptidase 9
17833 Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric
18127 Nos3 nitric oxide synthase 3, endothelial cell
21419 Tfap2b transcription factor AP-2 beta
Displaying all 3 entries
Gene ID Gene Symbol Description Source
24446 Hgf hepatocyte growth factor
24600 Nos3 nitric oxide synthase 3
81687 Mmp9 matrix metallopeptidase 9
Displaying all 2 entries
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein

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Last updated: December 9, 2024