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exfoliation syndrome
Summary
- Synonym
-
- Pseudoexfoliation glaucoma
- Pseudoexfoliation syndrome
- Definition
- A phacogenic glaucoma that is characterized by open-angle glaucoma related to deposition of extracellular fibrillar material in anterior segment structures, which blocks aqueous fluid outflow, raises intraocular pressure, and leads to eventual optic nerve atrophy and visual field loss. Exfoliation syndrome has_symptom progressive decreased vision, especially peripheral vision. Exfoliation syndrome is caused by age-related deposition of fibrillar material in anterior segment structures.
- Super Class
- iris disease phacogenic glaucoma
External Links
- Disease Ontology
- DOID:13641
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- MGI genotype (from TogoID)
Related Genes
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| O00206 | Toll-like receptor 4 | |
| P02649 | Apolipoprotein E | |
| P10909 | Clusterin | |
| Q04771 | Activin receptor type-1 | |
| Q08397 | Lysyl oxidase homolog 1 |
