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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
multiple sclerosis
Summary
- Synonym
-
- Generalized multiple sclerosis
- insular sclerosis
- Definition
- A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
- Super Class
- autoimmune disease of central nervous system demyelinating disease
External Links
- Disease Ontology
- DOID:2377
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- OMIM
- GARD
- MGI genotype (from TogoID)
- WikiPathways (from TogoID)
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 7087 | ICAM5 | intercellular adhesion molecule 5 | |
| 7099 | TLR4 | toll like receptor 4 | |
| 7124 | TNF | tumor necrosis factor | |
| 7167 | TPI1 | triosephosphate isomerase 1 | |
| 7412 | VCAM1 | vascular cell adhesion molecule 1 | |
| 7941 | PLA2G7 | phospholipase A2 group VII | |
| 8398 | PLA2G6 | phospholipase A2 group VI | |
| 8482 | SEMA7A | semaphorin 7A (JohnMiltonHagen blood group) | |
| 8630 | HSD17B6 | hydroxysteroid 17-beta dehydrogenase 6 | |
| 8794 | TNFRSF10C | TNF receptor superfamily member 10c |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11450 | Adipoq | adiponectin, C1Q and collagen domain containing | |
| 16002 | Igf2 | insulin-like growth factor 2 | |
| 21898 | Tlr4 | toll-like receptor 4 | |
| 21926 | Tnf | tumor necrosis factor | |
| 56336 | B4galt5 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 | |
| 56386 | B4galt6 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 | |
| 100198 | H6pd | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 36585 | beta4GalNAcTA | beta1,4-N-acetylgalactosaminyltransferase A | |
| 43222 | Tl | Toll | |
| 43425 | beta4GalNAcTB | beta1,4-N-acetylgalactosaminyltransferase B |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 446703 | b4galt5.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog | Xenopus laevis (African clawed frog) | |
| 548965 | b4galt6 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 | Xenopus tropicalis (tropical clawed frog) | |
| 549139 | b4galt5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | Xenopus tropicalis (tropical clawed frog) | |
| 779435 | b4galt6.L | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog | Xenopus laevis (African clawed frog) | |
| 108695277 | b4galt6.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog | Xenopus laevis (African clawed frog) | |
| 108702589 | b4galt5.S | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog | Xenopus laevis (African clawed frog) |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| Q9BXR0 | Queuine tRNA-ribosyltransferase catalytic subunit 1 | |
| Q9BZR6 | Reticulon-4 receptor | |
| Q9BZZ2 | Sialoadhesin | |
| Q9NPA2 | Matrix metalloproteinase-25 | |
| Q9NPH2 | Inositol-3-phosphate synthase 1 | |
| Q9P2W7 | Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | |
| Q9UBM7 | 7-dehydrocholesterol reductase | |
| Q9UBX8 | Beta-1,4-galactosyltransferase 6 | |
| Q9UEF7 | Klotho | |
| Q9ULY5 | C-type lectin domain family 4 member E |
