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Standards Ontologies Notations
multiple sclerosis

Summary
Synonym
  • Generalized multiple sclerosis
  • insular sclerosis
Definition
A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring.
Super Class
autoimmune disease of central nervous system demyelinating disease
External Links
Disease Ontology
DOID:2377
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 170 in total
Gene ID Gene Symbol Description Source
28 ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
43 ACHE acetylcholinesterase (Yt blood group)
50 ACO2 aconitase 2
142 PARP1 poly(ADP-ribose) polymerase 1
175 AGA aspartylglucosaminidase
176 ACAN aggrecan
231 AKR1B1 aldo-keto reductase family 1 member B
240 ALOX5 arachidonate 5-lipoxygenase
246 ALOX15 arachidonate 15-lipoxygenase
275 AMT aminomethyltransferase
Displaying all 7 entries
Gene ID Gene Symbol Description Source
11450 Adipoq adiponectin, C1Q and collagen domain containing
16002 Igf2 insulin-like growth factor 2
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
56336 B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
56386 B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
100198 H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
Displaying all 5 entries
Gene ID Gene Symbol Description Source
24483 Igf2 insulin-like growth factor 2
24835 Tnf tumor necrosis factor
29260 Tlr4 toll-like receptor 4
65196 B4galt6 beta-1,4-galactosyltransferase 6
362275 B4galt5 beta-1,4-galactosyltransferase 5
Displaying all 3 entries
Gene ID Gene Symbol Description Source
36585 beta4GalNAcTA beta1,4-N-acetylgalactosaminyltransferase A
43222 Tl Toll
43425 beta4GalNAcTB beta1,4-N-acetylgalactosaminyltransferase B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
393912 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
724080 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
446703 b4galt5.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 L homeolog Xenopus laevis (African clawed frog)
548965 b4galt6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 Xenopus tropicalis (tropical clawed frog)
549139 b4galt5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 Xenopus tropicalis (tropical clawed frog)
779435 b4galt6.L UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 L homeolog Xenopus laevis (African clawed frog)
108695277 b4galt6.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6 S homeolog Xenopus laevis (African clawed frog)
108702589 b4galt5.S UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 S homeolog Xenopus laevis (African clawed frog)
Displaying 1 entry
Gene ID Gene Symbol Description Source
190668 bre-4 Beta-1,4-N-acetylgalactosaminyltransferase bre-4
Displaying 1 entry
Gene ID Gene Symbol Description Source
856294 RHO1 Rho family GTPase RHO1
Related Glycoprotein
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024