acute interstitial pneumonia

Summary
Synonym
  • AIP
  • Hamman-Rich disease
  • Hamman-Rich syndrome
  • Idiopathic pulmonary fibrosis, acute fatal form
  • accelerated interstitial pneumonia
  • acute interstitial pneumonitis
Definition
A idiopathic interstitial pneumonia which develops suddenly and is severe. Initially, the lung shows edema, hyaline membranes, and interstitial acute inflammation. Later, it develops loose organizing fibrosis, mostly within alveolar septa and type II pneumocyte hyperplasia. Fever, cough, and difficulty breathing develop over 1 to 2 weeks, typically progressing to acute respiratory failure.
Super Class
idiopathic interstitial pneumonia
External Links
Disease Ontology
DOID:2800
Mondo Disease Ontology
UMLS
NCI Thesaurus
ORDO
GARD
Related Genes
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
279 AMY2A amylase alpha 2A
410 ARSA arylsulfatase A
1116 CHI3L1 chitinase 3 like 1
1462 VCAN versican
1634 DCN decorin
2023 ENO1 enolase 1
4153 MBL2 mannose binding lectin 2
5310 PKD1 polycystin 1, transient receptor potential channel interacting
5728 PTEN phosphatase and tensin homolog
5743 PTGS2 prostaglandin-endoperoxide synthase 2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024