acute interstitial pneumonia

Summary
Synonym
  • AIP
  • Hamman-Rich disease
  • Hamman-Rich syndrome
  • Idiopathic pulmonary fibrosis, acute fatal form
  • accelerated interstitial pneumonia
  • acute interstitial pneumonitis
Definition
A idiopathic interstitial pneumonia which develops suddenly and is severe. Initially, the lung shows edema, hyaline membranes, and interstitial acute inflammation. Later, it develops loose organizing fibrosis, mostly within alveolar septa and type II pneumocyte hyperplasia. Fever, cough, and difficulty breathing develop over 1 to 2 weeks, typically progressing to acute respiratory failure.
Super Class
idiopathic interstitial pneumonia
External Links
Disease Ontology
DOID:2800
Mondo Disease Ontology
UMLS
NCI Thesaurus
ORDO
GARD
Related Genes
Displaying entries 11 - 18 of 18 in total
Gene ID Gene Symbol Description Source
6385 SDC4 syndecan 4
6440 SFTPC surfactant protein C
6441 SFTPD surfactant protein D
8434 RECK reversion inducing cysteine rich protein with kazal motifs
8560 DEGS1 delta 4-desaturase, sphingolipid 1
23583 SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
653509 SFTPA1 surfactant protein A1
729238 SFTPA2 surfactant protein A2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024