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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
asthma
Summary
- Synonym
-
- bronchial hyperreactivity
- chronic obstructive asthma
- chronic obstructive asthma with acute exacerbation
- chronic obstructive asthma with status asthmaticus
- Definition
- A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing.
- Super Class
- bronchial disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 3371 | TNC | tenascin C | |
| 3383 | ICAM1 | intercellular adhesion molecule 1 | |
| 3458 | IFNG | interferon gamma | |
| 3459 | IFNGR1 | interferon gamma receptor 1 | |
| 3552 | IL1A | interleukin 1 alpha | |
| 3557 | IL1RN | interleukin 1 receptor antagonist | |
| 3558 | IL2 | interleukin 2 | |
| 3559 | IL2RA | interleukin 2 receptor subunit alpha | |
| 3560 | IL2RB | interleukin 2 receptor subunit beta | |
| 3562 | IL3 | interleukin 3 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 11421 | Ace | angiotensin I converting enzyme | |
| 11501 | Adam8 | a disintegrin and metallopeptidase domain 8 | |
| 11539 | Adora1 | adenosine A1 receptor | |
| 11540 | Adora2a | adenosine A2a receptor | |
| 11555 | Adrb2 | adrenergic receptor, beta 2 | |
| 11596 | Ager | advanced glycosylation end product-specific receptor | |
| 11607 | Agtr1a | angiotensin II receptor, type 1a | |
| 11609 | Agtr2 | angiotensin II receptor, type 2 | |
| 11699 | Ambp | alpha 1 microglobulin/bikunin precursor | |
| 12062 | Bdkrb2 | bradykinin receptor, beta 2 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 296504 | Abo2 | histo-blood group ABO system transferase 2 | |
| 304966 | Fcgr3a | Fc gamma receptor 3A | |
| 309212 | Ptgdr2 | prostaglandin D2 receptor 2 | |
| 309465 | Gsto2 | glutathione S-transferase omega 2 | |
| 310738 | Ngf | nerve growth factor | |
| 311061 | Itgb6 | integrin subunit beta 6 | |
| 312896 | Trpa1 | transient receptor potential cation channel, subfamily A, member 1 | |
| 363972 | Dpp10 | dipeptidyl peptidase like 10 | |
| 365769 | Il21 | interleukin 21 | |
| 498276 | Fcgr2al1 | Fc gamma receptor 2A like 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 58133 | ngfb | nerve growth factor b (beta polypeptide) | |
| 114424 | cdh1 | cadherin 1, type 1, E-cadherin (epithelial) | |
| 387303 | gbgt1l4 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4 | |
| 394082 | slc18a3b | solute carrier family 18 member 3b | |
| 406411 | rhoaa | ras homolog gene family, member Aa | |
| 406659 | rhoac | ras homolog gene family, member Ac | |
| 436718 | rhocb | ras homolog family member Cb | |
| 447881 | gbgt1l3 | globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 373580 | crhr1.2.S | corticotropin releasing hormone receptor 1, gene 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 397750 | hmgcr.L | 3-hydroxy-3-methylglutaryl-CoA reductase L homeolog | Xenopus laevis (African clawed frog) | |
| 397778 | tgfb1.L | transforming growth factor beta 1 L homeolog | Xenopus laevis (African clawed frog) | |
| 399298 | ntf3.L | neurotrophin 3 L homeolog | Xenopus laevis (African clawed frog) | |
| 495825 | abo.3.L | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog | Xenopus laevis (African clawed frog) | |
| 549437 | abo.3 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 | Xenopus tropicalis (tropical clawed frog) | |
| 549858 | abo.2 | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 | Xenopus tropicalis (tropical clawed frog) | |
| 550054 | abo | ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 | Xenopus tropicalis (tropical clawed frog) | |
| 100144634 | ace | angiotensin I converting enzyme | Xenopus tropicalis (tropical clawed frog) | |
| 100337618 | cdh1.S | cadherin 1, type 1 S homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 172841 | 45566 | Organic cation transporter 1 | |
| 174044 | sma-6 | Serine/threonine-protein kinase receptor sma-6 | |
| 174462 | let-23 | Receptor tyrosine-protein kinase let-23;receptor protein-tyrosine kinase | |
| 175182 | ver-1 | Protein ver-1 | |
| 175383 | zmp-2 | Matrix metalloproteinase-B | |
| 175504 | pat-3 | Integrin beta pat-3 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 178118 | trpa-1 | Ion transport domain-containing protein;Transient receptor potential cation channel subfamily A member 1 homolog | |
| 178215 | pgp-1 | Multidrug resistance protein pgp-1 | |
| 178274 | cho-1 | High-affinity choline transporter 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 850462 | GIT1 | Git1p | |
| 851171 | HMG2 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG2 | |
| 851977 | CTS2 | putative chitinase | |
| 853671 | STE6 | ATP-binding cassette a-factor transporter STE6 | |
| 853978 | NFT1 | putative multidrug transporter NFT1 | |
| 854394 | STE13 | Ste13p | |
| 854900 | HMG1 | hydroxymethylglutaryl-CoA reductase (NADPH) HMG1 | |
| 856294 | RHO1 | Rho family GTPase RHO1 |
- The Human Phenotype Ontology
| HPO ID | HPO Term |
|---|---|
| HP:0001426 | Non-Mendelian inheritance |
| HP:0000006 | Autosomal dominant inheritance |
| HP:0002099 | Asthma |
