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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
amyotrophic lateral sclerosis
Summary
- Synonym
-
- ALS
- Lou Gehrig's disease
- motor neuron disease, bulbar
- Definition
- A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- Super Class
- motor neuron disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 17758 | Map4 | microtubule-associated protein 4 | |
| 17762 | Mapt | microtubule-associated protein tau | |
| 18024 | Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | |
| 18039 | Nefl | neurofilament, light polypeptide | |
| 18040 | Nefm | neurofilament, medium polypeptide | |
| 18174 | Slc11a2 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | |
| 18412 | Sqstm1 | sequestosome 1 | |
| 18654 | Pgf | placental growth factor | |
| 19017 | Ppargc1a | peroxisome proliferative activated receptor, gamma, coactivator 1 alpha | |
| 19184 | Psmc5 | protease (prosome, macropain) 26S subunit, ATPase 5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 81687 | Mmp9 | matrix metallopeptidase 9 | |
| 83516 | Ppargc1a | PPARG coactivator 1 alpha | |
| 83613 | Nefl | neurofilament light chain | |
| 83619 | Nfe2l2 | NFE2 like bZIP transcription factor 2 | |
| 83785 | Vegfa | vascular endothelial growth factor A | |
| 84027 | Gsk3b | glycogen synthase kinase 3 beta | |
| 94203 | Pgf | placental growth factor | |
| 113959 | C5ar1 | complement C5a receptor 1 | |
| 170496 | Lcn2 | lipocalin 2 | |
| 287545 | Sarm1 | sterile alpha and TIR motif containing 1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38657 | vn | vein | |
| 38895 | Sarm | Sterile alpha and Armadillo motif | |
| 42490 | Mvl | Malvolio | |
| 42549 | InR | Insulin-like receptor | |
| 43223 | Lerp | lysosomal enzyme receptor protein | |
| 43469 | Ptp99A | Protein tyrosine phosphatase 99A | |
| 44811 | E(bx) | Enhancer of bithorax |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 447803 | pon1 | paraoxonase 1 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 798441 | mstnb | myostatin b | |
| 100004455 | epoa | erythropoietin a |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380341 | pon2.L | paraoxonase 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 432039 | pon2.S | paraoxonase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175182 | ver-1 | Protein ver-1 | |
| 175237 | daf-7 | Dauer larva development regulatory growth factor daf-7 | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175502 | tir-1 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 177882 | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180042 | dpf-1 | Dipeptidyl peptidase family member 1 |
