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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
amyotrophic lateral sclerosis
Summary
- Synonym
-
- ALS
- Lou Gehrig's disease
- motor neuron disease, bulbar
- Definition
- A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing.
- Super Class
- motor neuron disease
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 348 | APOE | apolipoprotein E | |
| 361 | AQP4 | aquaporin 4 | |
| 718 | C3 | complement C3 | |
| 728 | C5AR1 | complement C5a receptor 1 | |
| 842 | CASP9 | caspase 9 | |
| 1639 | DCTN1 | dynactin subunit 1 | |
| 1804 | DPP6 | dipeptidyl peptidase like 6 | |
| 2056 | EPO | erythropoietin | |
| 2130 | EWSR1 | EWS RNA binding protein 1 | |
| 2186 | BPTF | bromodomain PHD finger transcription factor |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 56637 | Gsk3b | glycogen synthase kinase 3 beta | |
| 74018 | Als2 | alsin Rho guanine nucleotide exchange factor | |
| 74772 | Atp13a2 | ATPase type 13A2 | |
| 83995 | Mmp1a | matrix metallopeptidase 1a (interstitial collagenase) | |
| 94232 | Ubqln4 | ubiquilin 4 | |
| 208727 | Hdac4 | histone deacetylase 4 | |
| 224088 | Atp13a3 | ATPase type 13A3 | |
| 233908 | Fus | fused in sarcoma | |
| 237868 | Sarm1 | sterile alpha and HEAT/Armadillo motif containing 1 | |
| 268878 | Atp13a5 | ATPase type 13A5 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 24232 | C3 | complement C3 | |
| 24335 | Epo | erythropoietin | |
| 24401 | Got1 | glutamic-oxaloacetic transaminase 1 | |
| 24588 | Nefm | neurofilament medium chain | |
| 25293 | Aqp4 | aquaporin 4 | |
| 25352 | Sod3 | superoxide dismutase 3 | |
| 25453 | Gdnf | glial cell derived neurotrophic factor | |
| 25459 | Hmgb1 | high mobility group box 1 | |
| 25589 | Kdr | kinase insert domain receptor | |
| 25613 | Ptprz1 | protein tyrosine phosphatase, receptor type Z1 |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 31248 | sgg | shaggy | |
| 36232 | Sod3 | Superoxide dismutase 3 | |
| 38657 | vn | vein | |
| 38895 | Sarm | Sterile alpha and Armadillo motif | |
| 42490 | Mvl | Malvolio | |
| 42549 | InR | Insulin-like receptor | |
| 43223 | Lerp | lysosomal enzyme receptor protein | |
| 43469 | Ptp99A | Protein tyrosine phosphatase 99A | |
| 44811 | E(bx) | Enhancer of bithorax |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 30682 | vegfaa | vascular endothelial growth factor Aa | |
| 403143 | sarm1 | sterile alpha and TIR motif containing 1 | |
| 447803 | pon1 | paraoxonase 1 | |
| 554230 | kdr | kinase insert domain receptor (a type III receptor tyrosine kinase) | |
| 798441 | mstnb | myostatin b | |
| 100004455 | epoa | erythropoietin a |
| Gene ID | Gene Symbol | Description | Source | Organism |
|---|---|---|---|---|
| 380341 | pon2.L | paraoxonase 2 L homeolog | Xenopus laevis (African clawed frog) | |
| 432039 | pon2.S | paraoxonase 2 S homeolog | Xenopus laevis (African clawed frog) | |
| 448598 | pon2 | paraoxonase 2 | Xenopus tropicalis (tropical clawed frog) | |
| 779087 | gdnf.L | glial cell derived neurotrophic factor L homeolog | Xenopus laevis (African clawed frog) |
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 175182 | ver-1 | Protein ver-1 | |
| 175237 | daf-7 | Dauer larva development regulatory growth factor daf-7 | |
| 175410 | daf-2 | Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase | |
| 175502 | tir-1 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;NAD(+) hydrolase tir-1;Sterile alpha and TIR motif-containing protein 1 | |
| 177044 | smf-3 | NRAMP-like transporter smf-3 | |
| 177343 | skn-1 | BZIP domain-containing protein;Protein skinhead-1 | |
| 177882 | glt-3 | Putative sodium-dependent excitatory amino acid transporter glt-3 | |
| 178748 | zmp-3 | Matrix metalloproteinase-C | |
| 179991 | zmp-4 | Hemopexin;Peptidase metallopeptidase domain-containing protein | |
| 180042 | dpf-1 | Dipeptidyl peptidase family member 1 |
