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Standards Ontologies Notations
pulmonary fibrosis

Summary
Synonym
  • Fibrosis of lung
Definition
An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation.
Super Class
interstitial lung disease
Disease Ontology
DOID:3770
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
WikiPathways (from TogoID)
Related Genes
Displaying entries 1 - 10 of 69 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
182 JAG1 jagged canonical Notch ligand 1
183 AGT angiotensinogen
240 ALOX5 arachidonate 5-lipoxygenase
301 ANXA1 annexin A1
572 BAD BCL2 associated agonist of cell death
623 BDKRB1 bradykinin receptor B1
627 BDNF brain derived neurotrophic factor
847 CAT catalase
948 CD36 CD36 molecule (CD36 blood group)
Displaying entries 21 - 30 of 56 in total
Gene ID Gene Symbol Description Source
15516 Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1
15894 Icam1 intercellular adhesion molecule 1
16009 Igfbp3 insulin-like growth factor binding protein 3
16163 Il13 interleukin 13
16168 Il15 interleukin 15
16171 Il17a interleukin 17A
16175 Il1a interleukin 1 alpha
16181 Il1rn interleukin 1 receptor antagonist
16182 Il18r1 interleukin 18 receptor 1
16189 Il4 interleukin 4
Displaying entries 31 - 40 of 42 in total
Gene ID Gene Symbol Description Source
89824 Chi3l1 chitinase 3 like 1
114099 Cysltr1 cysteinyl leukotriene receptor 1
114114 Dnm1l dynamin 1-like
116510 Timp1 TIMP metallopeptidase inhibitor 1
116553 Il13 interleukin 13
116630 Csf2 colony stimulating factor 2
117029 Ccr5 C-C motif chemokine receptor 5
117108 B3gat1 beta-1,3-glucuronyltransferase 1
192155 Sftpb surfactant protein B
287287 Il4 interleukin 4
Displaying entries 1 - 10 of 16 in total
Gene ID Gene Symbol Description Source
31293 N Notch
31926 Idgf4 Imaginal disc growth factor 4
34189 Acer Angiotensin-converting enzyme-related
34282 GlcAT-S Glucuronyltransferase S
34805 Ance Angiotensin converting enzyme
34978 Idgf1 Imaginal disc growth factor 1
34979 Idgf2 Imaginal disc growth factor 2
34981 Idgf3 Imaginal disc growth factor 3
36868 Idgf6 Imaginal disc growth factor 6
37104 Idgf5 Imaginal disc growth factor 5
Displaying all 8 entries
Gene ID Gene Symbol Description Source
30718 notch1a notch receptor 1a
58133 ngfb nerve growth factor b (beta polypeptide)
114424 cdh1 cadherin 1, type 1, E-cadherin (epithelial)
140421 jag1a jagged canonical Notch ligand 1a
386856 pdgfra platelet-derived growth factor receptor, alpha polypeptide
548607 b3gat1a beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) a
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
100332644 b3gat1b beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) b
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
397778 tgfb1.L transforming growth factor beta 1 L homeolog Xenopus laevis (African clawed frog)
100037842 notch1 notch 1 receptor Xenopus tropicalis (tropical clawed frog)
100037907 b3gat1 beta-1,3-glucuronyltransferase 1 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100337618 cdh1.S cadherin 1, type 1 S homeolog Xenopus laevis (African clawed frog)
108709389 ngf.S nerve growth factor S homeolog Xenopus laevis (African clawed frog)
Displaying entries 11 - 15 of 15 in total
Gene ID Gene Symbol Description Source
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180628 cht-1 putative endochitinase
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
180812 scav-1 SCAVenger receptor (CD36 family) related
Displaying all 2 entries
Gene ID Gene Symbol Description Source
851977 CTS2 putative chitinase
853177 APL6 Apl6p
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024