Paget's disease of bone

Summary
Synonym
  • Paget disease of bone
  • Paget's bone disease
  • osseous Paget's disease
  • osteitis deformans
Definition
A bone formation disease that has_material_basis_in hyperactive osteoclast which results_in abnormal osteoblast bone formation located_in skull, located_in pelvis, located_in vertebral column, located_in set of limbs.
Super Class
hyperostosis
Disease Ontology
DOID:5408
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
ORDO
OMIM
GARD
MGI genotype (from TogoID)
Related Genes
Displaying all 6 entries
Gene ID Gene Symbol Description Source
3635 INPP5D inositol polyphosphate-5-phosphatase D
4982 TNFRSF11B TNF receptor superfamily member 11b
7415 VCP valosin containing protein
8792 TNFRSF11A TNF receptor superfamily member 11a
8878 SQSTM1 sequestosome 1
10133 OPTN optineurin
Displaying all 3 entries
Gene ID Gene Symbol Description Source
18383 Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
18412 Sqstm1 sequestosome 1
21934 Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Displaying 1 entry
Gene ID Gene Symbol Description Source
25341 Tnfrsf11b TNF receptor superfamily member 11B

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024